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The map label for this gene is cotA [H]

Identifier: 78223780

GI number: 78223780

Start: 2933896

End: 2936100

Strand: Reverse

Name: cotA [H]

Synonym: Gmet_2583

Alternate gene names: 78223780

Gene position: 2936100-2933896 (Counterclockwise)

Preceding gene: 78223781

Following gene: 78223779

Centisome position: 73.45

GC content: 59.41

Gene sequence:

>2205_bases
ATGAACAAGATCAGCAGAAGGAAATTCCTGCAGATAAGCGGATTTGCGGCAGGCGCTACCATGCTACCGCTGCCGATGAA
GTGGCTCGGGCGGCGTGATGTCTTTGCTTTCTACCAGACGCCGGCCAACCAACTCGGACTCTTTAAAACCAAGCTGCGGG
GCGTTGGCCCGGCCGGCATCCCGCTGGCGACTCCGGATGGGTCGGCAGGTATAGGGGGGGCTGCCCATTACACTTTCAAT
ATCGGGCAGTTCACCGATCAGTTGCACCCCGCTCTTGGTCCGACGACCCTCTGGGGGTACAATCCACAGAATGCCTTGGG
CGTTACGGGGGTTCCGGCCCAGAAGCACCTGGGTGGAATCATTGTGGCAAATAAGGGGGTGCCGATCCAGCTCACGTTCA
CCAACAATCTTCCGAACAAGCATATCCTGCCTGTGGACAAGAGCGCCAATTTTCCCGATGCGGCGCAACATGTAAATGAC
GCTTCCGTGCACCTCCATGGCGGATTTGTCCCGTGGATCAGCGATGGCGGACCCATGGCCTATTTTGGCCCCCCGACCAT
CGCTAACCCCAATGGCGTTTACGGCCCGAGTGTTTCCGACGGAGTGAATCCGAACCTGTTTCAGCAGGTGTTGAACTCTA
ACCTGGATCCGGGGCAGGCCGAGTATTACTACCCCAACCAGCAGAGCGCCCGGATGATGTGGTATCACGACCACACCCAC
GACTGCACGCGTCTCAACGCGTACGCAGGACTTGCCTCCGTCTACCTCATTCGGGATACCTTCGAGGGGAACCTGAGGAA
CCTGGGACTTCCCGATTATATCGAAAACGGGGGATTCGAAATCCCCCTCGTCATTCAGGACAAGATCTTCGTCGGTTCGA
ATATTGGCCTCTATGACCCGACGTGGCCGGGGCCGAGAACGCCGGGAAGCCTCTGGTACCCCCATATTTACGAGAAGAAC
CGCTGGCACAAGGTTTACAGCCCCCTGCGGATGCCTGCCCCCTCAGCCGTTCCCGAGATGTTCGGAGATACCATGCTGGT
CAACGGTACGGTATTCCCAGAGGCCACAGTGGAGGCGCGTCCCTACCGTCTGCGGATTCTCAACGTCTGCAATGCCCGGT
TCATGAACCTGCAGCTCTATGTGGACGACGGCAGCCTGAATGGTGTTACCTTGAATCCCGTTACCGGCAATCCCCCGCCA
AGTGCCGCATTTGTGGACGGCACACAGAACCAGCCGGCCGTCCTCCAGCTCGGCACCGAGGGGGGCTTCCTGCCAACTCC
GGTGCTCGTCCCGACCAATGTGCCGTTCGGCTTCGATCCGGTGACCGGCGCCCCCACCGGGAGCATCCTCATGGGGCCGG
CGGAGCGGGTCGATCTCATCGTCGACTTCAAAAATTACATCGGGAAAAATGTTATCCTTTACTCCGATGCGCCGGCGCCG
TTCCCCTTGGGAGATCCGCGCAACGACTACTTCCCGCAGTGGAACACCGCAGGCAACCCGGCCAACGCCCTGACCAAGAA
CGGTTTCGGCCCCAATACCCGCGTCCTCATGCGATTCAAAGTGAAGGCGGCGACCAGCAGCGTCGCGGCTGTTTCGATCA
ATACGGCCACCGATCTGTCGGCCGGAAACGATCCCCTTCCGCTCCCCGGAGGAGCTCCGATCATCGGTGGTGCGCTGCAG
CTCCCTCCGGGAGTTCCTGTCAGACCGCTCACCCTGAACGAGGTTTTCGACAGCTACGGCCGTCTCCTCCAACTCCTCGG
GACGAACGTCCCCACTGCCAACGCCTTTGGCTTGGGCTACATGGACAATGCGACGGAGGTTGTCAATCTTGTGAATGGGG
AGAAGGTGGAGATATGGCAGATAGCCAACCTGACCGGCGACACCCATCCGATTCACTTCCACCTGGTGAACGCCCAGCTC
CTCGGGCGGCAGCCCTTTGACGTGGTGCACTATAACGGGACTCCCACGTATATCGGCCCGGCCCGCGGTCCCGACCCGAA
CGAAACGGGATTCAAGGAAACGATCCGGATGAACCCCGGCGAGGTCACGACGGTGATTATGAGGTTTAAATTCCCGACGG
TCCCGTTCACCGTCCCGAACAGCCTGAACCCGAACTTGGGGATAAGCGGGAAAGAGTACGTGTGGCATTGCCATATCCTC
GATCATGAGGAGCACGACATGATGAGGCCGCTGGTGGTCATCTAG

Upstream 100 bases:

>100_bases
CCTGGGAGTGTTCCTGTTCAGAAAAAGAATAACTGGAATCTCCTTTTAGACCGTTGAATGGACTTGTCTGGGCTTGCAGC
TAACAGAAAGGACGGACCAT

Downstream 100 bases:

>100_bases
AATGAGCCTCCAGGCGACGACAGCAACCCGGTGCGTTAGCGCCGGGTGAGGAGAAGCCCCGCGACGTTTTGCGGGGCTTC
TGTTTGGGATCACGGGAATC

Product: twin-arginine translocation pathway signal

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 734; Mature: 734

Protein sequence:

>734_residues
MNKISRRKFLQISGFAAGATMLPLPMKWLGRRDVFAFYQTPANQLGLFKTKLRGVGPAGIPLATPDGSAGIGGAAHYTFN
IGQFTDQLHPALGPTTLWGYNPQNALGVTGVPAQKHLGGIIVANKGVPIQLTFTNNLPNKHILPVDKSANFPDAAQHVND
ASVHLHGGFVPWISDGGPMAYFGPPTIANPNGVYGPSVSDGVNPNLFQQVLNSNLDPGQAEYYYPNQQSARMMWYHDHTH
DCTRLNAYAGLASVYLIRDTFEGNLRNLGLPDYIENGGFEIPLVIQDKIFVGSNIGLYDPTWPGPRTPGSLWYPHIYEKN
RWHKVYSPLRMPAPSAVPEMFGDTMLVNGTVFPEATVEARPYRLRILNVCNARFMNLQLYVDDGSLNGVTLNPVTGNPPP
SAAFVDGTQNQPAVLQLGTEGGFLPTPVLVPTNVPFGFDPVTGAPTGSILMGPAERVDLIVDFKNYIGKNVILYSDAPAP
FPLGDPRNDYFPQWNTAGNPANALTKNGFGPNTRVLMRFKVKAATSSVAAVSINTATDLSAGNDPLPLPGGAPIIGGALQ
LPPGVPVRPLTLNEVFDSYGRLLQLLGTNVPTANAFGLGYMDNATEVVNLVNGEKVEIWQIANLTGDTHPIHFHLVNAQL
LGRQPFDVVHYNGTPTYIGPARGPDPNETGFKETIRMNPGEVTTVIMRFKFPTVPFTVPNSLNPNLGISGKEYVWHCHIL
DHEEHDMMRPLVVI

Sequences:

>Translated_734_residues
MNKISRRKFLQISGFAAGATMLPLPMKWLGRRDVFAFYQTPANQLGLFKTKLRGVGPAGIPLATPDGSAGIGGAAHYTFN
IGQFTDQLHPALGPTTLWGYNPQNALGVTGVPAQKHLGGIIVANKGVPIQLTFTNNLPNKHILPVDKSANFPDAAQHVND
ASVHLHGGFVPWISDGGPMAYFGPPTIANPNGVYGPSVSDGVNPNLFQQVLNSNLDPGQAEYYYPNQQSARMMWYHDHTH
DCTRLNAYAGLASVYLIRDTFEGNLRNLGLPDYIENGGFEIPLVIQDKIFVGSNIGLYDPTWPGPRTPGSLWYPHIYEKN
RWHKVYSPLRMPAPSAVPEMFGDTMLVNGTVFPEATVEARPYRLRILNVCNARFMNLQLYVDDGSLNGVTLNPVTGNPPP
SAAFVDGTQNQPAVLQLGTEGGFLPTPVLVPTNVPFGFDPVTGAPTGSILMGPAERVDLIVDFKNYIGKNVILYSDAPAP
FPLGDPRNDYFPQWNTAGNPANALTKNGFGPNTRVLMRFKVKAATSSVAAVSINTATDLSAGNDPLPLPGGAPIIGGALQ
LPPGVPVRPLTLNEVFDSYGRLLQLLGTNVPTANAFGLGYMDNATEVVNLVNGEKVEIWQIANLTGDTHPIHFHLVNAQL
LGRQPFDVVHYNGTPTYIGPARGPDPNETGFKETIRMNPGEVTTVIMRFKFPTVPFTVPNSLNPNLGISGKEYVWHCHIL
DHEEHDMMRPLVVI
>Mature_734_residues
MNKISRRKFLQISGFAAGATMLPLPMKWLGRRDVFAFYQTPANQLGLFKTKLRGVGPAGIPLATPDGSAGIGGAAHYTFN
IGQFTDQLHPALGPTTLWGYNPQNALGVTGVPAQKHLGGIIVANKGVPIQLTFTNNLPNKHILPVDKSANFPDAAQHVND
ASVHLHGGFVPWISDGGPMAYFGPPTIANPNGVYGPSVSDGVNPNLFQQVLNSNLDPGQAEYYYPNQQSARMMWYHDHTH
DCTRLNAYAGLASVYLIRDTFEGNLRNLGLPDYIENGGFEIPLVIQDKIFVGSNIGLYDPTWPGPRTPGSLWYPHIYEKN
RWHKVYSPLRMPAPSAVPEMFGDTMLVNGTVFPEATVEARPYRLRILNVCNARFMNLQLYVDDGSLNGVTLNPVTGNPPP
SAAFVDGTQNQPAVLQLGTEGGFLPTPVLVPTNVPFGFDPVTGAPTGSILMGPAERVDLIVDFKNYIGKNVILYSDAPAP
FPLGDPRNDYFPQWNTAGNPANALTKNGFGPNTRVLMRFKVKAATSSVAAVSINTATDLSAGNDPLPLPGGAPIIGGALQ
LPPGVPVRPLTLNEVFDSYGRLLQLLGTNVPTANAFGLGYMDNATEVVNLVNGEKVEIWQIANLTGDTHPIHFHLVNAQL
LGRQPFDVVHYNGTPTYIGPARGPDPNETGFKETIRMNPGEVTTVIMRFKFPTVPFTVPNSLNPNLGISGKEYVWHCHIL
DHEEHDMMRPLVVI

Specific function: Involved in brown pigmentation during sporogenesis [H]

COG id: COG2132

COG function: function code Q; Putative multicopper oxidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To S.antibioticus phenoxazinone synthase (phsA) [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001117
- InterPro:   IPR011706
- InterPro:   IPR011707
- InterPro:   IPR008972 [H]

Pfam domain/function: PF00394 Cu-oxidase; PF07731 Cu-oxidase_2; PF07732 Cu-oxidase_3 [H]

EC number: NA

Molecular weight: Translated: 79590; Mature: 79590

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKISRRKFLQISGFAAGATMLPLPMKWLGRRDVFAFYQTPANQLGLFKTKLRGVGPAGI
CCCCCCCEEEEEECCCCCCEECCCCHHHCCCCCEEEEECCCCHHHCHHHHHHCCCCCCCC
PLATPDGSAGIGGAAHYTFNIGQFTDQLHPALGPTTLWGYNPQNALGVTGVPAQKHLGGI
EEECCCCCCCCCCEEEEEEEHHHHHHHHCCCCCCCEECCCCCCCCCCCCCCCHHHHCCEE
IVANKGVPIQLTFTNNLPNKHILPVDKSANFPDAAQHVNDASVHLHGGFVPWISDGGPMA
EEECCCCEEEEEECCCCCCCEEEECCCCCCCCHHHHHCCCCEEEEECCEEEEECCCCCEE
YFGPPTIANPNGVYGPSVSDGVNPNLFQQVLNSNLDPGQAEYYYPNQQSARMMWYHDHTH
EECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEECCCCCCCEEEEEECCCC
DCTRLNAYAGLASVYLIRDTFEGNLRNLGLPDYIENGGFEIPLVIQDKIFVGSNIGLYDP
CCHHHHHHHCCEEEEEEEECCCCCCCCCCCCHHHHCCCEEEEEEEECEEEECCCCCCCCC
TWPGPRTPGSLWYPHIYEKNRWHKVYSPLRMPAPSAVPEMFGDTMLVNGTVFPEATVEAR
CCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCHHHHHCCCEEEEECEECCCCCCCCC
PYRLRILNVCNARFMNLQLYVDDGSLNGVTLNPVTGNPPPSAAFVDGTQNQPAVLQLGTE
CEEEEEEEECCCEEEEEEEEEECCCCCCEEECCCCCCCCCCCEEECCCCCCCEEEEECCC
GGFLPTPVLVPTNVPFGFDPVTGAPTGSILMGPAERVDLIVDFKNYIGKNVILYSDAPAP
CCCCCCCEEEECCCCCCCCCCCCCCCCCEEECCHHHEEEEEEEHHHHCCEEEEECCCCCC
FPLGDPRNDYFPQWNTAGNPANALTKNGFGPNTRVLMRFKVKAATSSVAAVSINTATDLS
CCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCEEEEEEEEEECCCCEEEEEEECCCCCC
AGNDPLPLPGGAPIIGGALQLPPGVPVRPLTLNEVFDSYGRLLQLLGTNVPTANAFGLGY
CCCCCCCCCCCCCEECCEEECCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCCCEECCCC
MDNATEVVNLVNGEKVEIWQIANLTGDTHPIHFHLVNAQLLGRQPFDVVHYNGTPTYIGP
CCCHHHHHHHCCCCEEEEEEEECCCCCCCEEEEEEECHHHHCCCCCEEEEECCCCCEECC
ARGPDPNETGFKETIRMNPGEVTTVIMRFKFPTVPFTVPNSLNPNLGISGKEYVWHCHIL
CCCCCCCCCCCHHEEECCCCCEEEEEEEEECCCCCEECCCCCCCCCCCCCCCEEEEEEEE
DHEEHDMMRPLVVI
CCCCHHHCCCEEEC
>Mature Secondary Structure
MNKISRRKFLQISGFAAGATMLPLPMKWLGRRDVFAFYQTPANQLGLFKTKLRGVGPAGI
CCCCCCCEEEEEECCCCCCEECCCCHHHCCCCCEEEEECCCCHHHCHHHHHHCCCCCCCC
PLATPDGSAGIGGAAHYTFNIGQFTDQLHPALGPTTLWGYNPQNALGVTGVPAQKHLGGI
EEECCCCCCCCCCEEEEEEEHHHHHHHHCCCCCCCEECCCCCCCCCCCCCCCHHHHCCEE
IVANKGVPIQLTFTNNLPNKHILPVDKSANFPDAAQHVNDASVHLHGGFVPWISDGGPMA
EEECCCCEEEEEECCCCCCCEEEECCCCCCCCHHHHHCCCCEEEEECCEEEEECCCCCEE
YFGPPTIANPNGVYGPSVSDGVNPNLFQQVLNSNLDPGQAEYYYPNQQSARMMWYHDHTH
EECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEECCCCCCCEEEEEECCCC
DCTRLNAYAGLASVYLIRDTFEGNLRNLGLPDYIENGGFEIPLVIQDKIFVGSNIGLYDP
CCHHHHHHHCCEEEEEEEECCCCCCCCCCCCHHHHCCCEEEEEEEECEEEECCCCCCCCC
TWPGPRTPGSLWYPHIYEKNRWHKVYSPLRMPAPSAVPEMFGDTMLVNGTVFPEATVEAR
CCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCHHHHHCCCEEEEECEECCCCCCCCC
PYRLRILNVCNARFMNLQLYVDDGSLNGVTLNPVTGNPPPSAAFVDGTQNQPAVLQLGTE
CEEEEEEEECCCEEEEEEEEEECCCCCCEEECCCCCCCCCCCEEECCCCCCCEEEEECCC
GGFLPTPVLVPTNVPFGFDPVTGAPTGSILMGPAERVDLIVDFKNYIGKNVILYSDAPAP
CCCCCCCEEEECCCCCCCCCCCCCCCCCEEECCHHHEEEEEEEHHHHCCEEEEECCCCCC
FPLGDPRNDYFPQWNTAGNPANALTKNGFGPNTRVLMRFKVKAATSSVAAVSINTATDLS
CCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCEEEEEEEEEECCCCEEEEEEECCCCCC
AGNDPLPLPGGAPIIGGALQLPPGVPVRPLTLNEVFDSYGRLLQLLGTNVPTANAFGLGY
CCCCCCCCCCCCCEECCEEECCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCCCEECCCC
MDNATEVVNLVNGEKVEIWQIANLTGDTHPIHFHLVNAQLLGRQPFDVVHYNGTPTYIGP
CCCHHHHHHHCCCCEEEEEEEECCCCCCCEEEEEEECHHHHCCCCCEEEEECCCCCEECC
ARGPDPNETGFKETIRMNPGEVTTVIMRFKFPTVPFTVPNSLNPNLGISGKEYVWHCHIL
CCCCCCCCCCCHHEEECCCCCEEEEEEEEECCCCCEECCCCCCCCCCCCCCCEEEEEEEE
DHEEHDMMRPLVVI
CCCCHHHCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969499; 9455482; 9384377; 2821284; 3135411 [H]