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The map label for this gene is atoS [H]

Identifier: 78223759

GI number: 78223759

Start: 2908697

End: 2909788

Strand: Direct

Name: atoS [H]

Synonym: Gmet_2562

Alternate gene names: 78223759

Gene position: 2908697-2909788 (Clockwise)

Preceding gene: 78223758

Following gene: 78223760

Centisome position: 72.76

GC content: 65.48

Gene sequence:

>1092_bases
ATGAGCCCGGAAAGCCCCAACGAAGCGTTCCTTGCCACCATCATCGACAGCGTCGGCGACGGGGTCATCGTCATCGACCT
GGGGGGGCGGATCACCCTCATGAACCCTGCGGCCGAGGAGATCATCGCCATCTCCCGGCGCCAGGCCATGGGGCACCCCT
TCGCGGCCCTCCTCGGCAGTCAGGAGATTCTGGTGGATATGGTCGCCAAGACCGCCGCCACCGGCATGACCATCTCCGAC
AACGAGAACATCGTCATCAGGAAGGCGAAGCAGCTTACCCCGGTCGCGGTCACCACGTTTCCGCTCCTGCGGCAGGACGG
CGAGCCCATCGGCACCATCCTCATGCTGCGGGACCTGACGAACATCCGGGAACTGGAAGATGCGGTCCGCCACGCCGACC
GGCTCTCCACCCTCGGCACCCTGGCGGCGGGCCTGGCCCACGAGATCAAGAACCCTCTGGGGGGGATCAAGGGGGCGGCC
CAGCTTCTGGAAATGGAGCTCCCCCCCGAGAGCGAACTGCGGGACAACGTCCGGGTCGTGGTCAGGGAGGTGGACCGGGT
CAACCGGATCGTGGAGGAGCTCCTGGCACTCTCATCGCCCCGCAAGCTCCAACTCACCAAGGTGAACCTCCACAAGATCC
TCGGCGACATTGTCACTCTCAGGAAACGGGCCACGGAAGGGAAGTCCGTCACGTTCCAGCAGCAGTTCGACCCGAGCATC
CCGCCGATCCTGGCCGACGAGGGGCTCCTGACCCAGCTCTTCCTGAACCTGATCAAGAACGCCGTGGAGGCGGTGGACGA
GCGGGGCACCATCCGGGTCGCGAGCCGGGTCCTCTCCGACTACAGCATGACCCCGAAGGGGGAGCGCCGCTCCCGCATGG
TGGCCGTCGATGTCCGCGACGACGGCCCCGGTATCCCCAGGGAGCAACTGGAGCAGCTCTTCACCCCCTTCTTCACCACC
AAGGCCAAGGGGACCGGACTCGGCCTCGCCATCTGCCAGAAGATCGTCACAGAGCACCGGGGCATGCTCAAGGTGGAATC
GGACCCGGGCACGGGGACGACGTTCACGGTGATGCTGCCGTTAATTCAGTAA

Upstream 100 bases:

>100_bases
GTCTCTCCGGCGCGGCCCAGTTCCGCAAGGCCGTCAACATCATCGAGGGAAAGGAAGCCCTTCTCGAAGCGCTGCACCGC
TTCTTCGCGCCGGAGGCGCC

Downstream 100 bases:

>100_bases
CCAGGGACCAGGAACCGGGGACCAGTGGAATCAAAGTCAAGCGACTTTCGGTTTTACCGGTCCCCGGTCCCCGGTCCCGG
ATTTCCGAGGTTTTATCATG

Product: signal transduction histidine kinase, nitrogen specific, NtrB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MSPESPNEAFLATIIDSVGDGVIVIDLGGRITLMNPAAEEIIAISRRQAMGHPFAALLGSQEILVDMVAKTAATGMTISD
NENIVIRKAKQLTPVAVTTFPLLRQDGEPIGTILMLRDLTNIRELEDAVRHADRLSTLGTLAAGLAHEIKNPLGGIKGAA
QLLEMELPPESELRDNVRVVVREVDRVNRIVEELLALSSPRKLQLTKVNLHKILGDIVTLRKRATEGKSVTFQQQFDPSI
PPILADEGLLTQLFLNLIKNAVEAVDERGTIRVASRVLSDYSMTPKGERRSRMVAVDVRDDGPGIPREQLEQLFTPFFTT
KAKGTGLGLAICQKIVTEHRGMLKVESDPGTGTTFTVMLPLIQ

Sequences:

>Translated_363_residues
MSPESPNEAFLATIIDSVGDGVIVIDLGGRITLMNPAAEEIIAISRRQAMGHPFAALLGSQEILVDMVAKTAATGMTISD
NENIVIRKAKQLTPVAVTTFPLLRQDGEPIGTILMLRDLTNIRELEDAVRHADRLSTLGTLAAGLAHEIKNPLGGIKGAA
QLLEMELPPESELRDNVRVVVREVDRVNRIVEELLALSSPRKLQLTKVNLHKILGDIVTLRKRATEGKSVTFQQQFDPSI
PPILADEGLLTQLFLNLIKNAVEAVDERGTIRVASRVLSDYSMTPKGERRSRMVAVDVRDDGPGIPREQLEQLFTPFFTT
KAKGTGLGLAICQKIVTEHRGMLKVESDPGTGTTFTVMLPLIQ
>Mature_362_residues
SPESPNEAFLATIIDSVGDGVIVIDLGGRITLMNPAAEEIIAISRRQAMGHPFAALLGSQEILVDMVAKTAATGMTISDN
ENIVIRKAKQLTPVAVTTFPLLRQDGEPIGTILMLRDLTNIRELEDAVRHADRLSTLGTLAAGLAHEIKNPLGGIKGAAQ
LLEMELPPESELRDNVRVVVREVDRVNRIVEELLALSSPRKLQLTKVNLHKILGDIVTLRKRATEGKSVTFQQQFDPSIP
PILADEGLLTQLFLNLIKNAVEAVDERGTIRVASRVLSDYSMTPKGERRSRMVAVDVRDDGPGIPREQLEQLFTPFFTTK
AKGTGLGLAICQKIVTEHRGMLKVESDPGTGTTFTVMLPLIQ

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=354, Percent_Identity=36.1581920903955, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI1790436, Length=245, Percent_Identity=38.7755102040816, Blast_Score=171, Evalue=5e-44,
Organism=Escherichia coli, GI1790300, Length=352, Percent_Identity=32.6704545454545, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI48994928, Length=274, Percent_Identity=28.1021897810219, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI145693157, Length=265, Percent_Identity=29.811320754717, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1790567, Length=362, Percent_Identity=26.5193370165746, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1789149, Length=236, Percent_Identity=30.5084745762712, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1786600, Length=356, Percent_Identity=24.438202247191, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788393, Length=238, Percent_Identity=26.890756302521, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1790346, Length=234, Percent_Identity=26.4957264957265, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789808, Length=226, Percent_Identity=26.1061946902655, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788713, Length=264, Percent_Identity=23.8636363636364, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1786912, Length=247, Percent_Identity=27.1255060728745, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI87081816, Length=238, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1790861, Length=206, Percent_Identity=28.6407766990291, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1786783, Length=241, Percent_Identity=25.7261410788382, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87082128, Length=244, Percent_Identity=25.8196721311475, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788279, Length=267, Percent_Identity=23.2209737827715, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 39583; Mature: 39451

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPESPNEAFLATIIDSVGDGVIVIDLGGRITLMNPAAEEIIAISRRQAMGHPFAALLGS
CCCCCCCHHHHHHHHHHHCCCEEEEECCCEEEEECCHHHHHHHHHHHHHCCCCHHHHHCC
QEILVDMVAKTAATGMTISDNENIVIRKAKQLTPVAVTTFPLLRQDGEPIGTILMLRDLT
HHHHHHHHHHHHHCCCEECCCCCEEEEECCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHH
NIRELEDAVRHADRLSTLGTLAAGLAHEIKNPLGGIKGAAQLLEMELPPESELRDNVRVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHH
VREVDRVNRIVEELLALSSPRKLQLTKVNLHKILGDIVTLRKRATEGKSVTFQQQFDPSI
HHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCEEEHHCCCCCC
PPILADEGLLTQLFLNLIKNAVEAVDERGTIRVASRVLSDYSMTPKGERRSRMVAVDVRD
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEECC
DGPGIPREQLEQLFTPFFTTKAKGTGLGLAICQKIVTEHRGMLKVESDPGTGTTFTVMLP
CCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEEE
LIQ
CCC
>Mature Secondary Structure 
SPESPNEAFLATIIDSVGDGVIVIDLGGRITLMNPAAEEIIAISRRQAMGHPFAALLGS
CCCCCCHHHHHHHHHHHCCCEEEEECCCEEEEECCHHHHHHHHHHHHHCCCCHHHHHCC
QEILVDMVAKTAATGMTISDNENIVIRKAKQLTPVAVTTFPLLRQDGEPIGTILMLRDLT
HHHHHHHHHHHHHCCCEECCCCCEEEEECCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHH
NIRELEDAVRHADRLSTLGTLAAGLAHEIKNPLGGIKGAAQLLEMELPPESELRDNVRVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHH
VREVDRVNRIVEELLALSSPRKLQLTKVNLHKILGDIVTLRKRATEGKSVTFQQQFDPSI
HHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCEEEHHCCCCCC
PPILADEGLLTQLFLNLIKNAVEAVDERGTIRVASRVLSDYSMTPKGERRSRMVAVDVRD
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEECC
DGPGIPREQLEQLFTPFFTTKAKGTGLGLAICQKIVTEHRGMLKVESDPGTGTTFTVMLP
CCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEEE
LIQ
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]