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The map label for this gene is rpfG [H]

Identifier: 78223756

GI number: 78223756

Start: 2905684

End: 2907345

Strand: Direct

Name: rpfG [H]

Synonym: Gmet_2559

Alternate gene names: 78223756

Gene position: 2905684-2907345 (Clockwise)

Preceding gene: 78223746

Following gene: 78223758

Centisome position: 72.69

GC content: 62.09

Gene sequence:

>1662_bases
ATGATCGACACGTTCAACGCGGTTATCGAGGGAAGTGAGCGTCTGAGCGGTCTCGCCGACGTGGACGAGGTAGTGAAGGA
CCTGTCCCGGCTGCTCAAGAGGCTGGTCAAGAGCAGATGGATTGCCGTTTATTTCTTCGACCGGGAGCGACGCGATTTCG
CACCGGCCAGAAGCTACGGCCTTCCTGCCCGCTTCGTCCCCATCTTCCGGGATATGCCCCTTGTCCCCGACAAGATCCCC
CTTCTCAAGGGGCTGCTCCAGAAGAAACAGCATCTGCTCCTGTCCGACCCGAGCGTGTCGCACCTCATTCCCCAGAAGTT
GAGAAAGCTCCTGCGCAACCTGACGCTGCTGGCCGTGCCGATGGTGGCCCGCAACCAGGTAATCGGGGCGGTATTCGTGG
CCCGGGCCAGGGAACTCCCCCCCTTTTCCCCCGATGAAGTGGCGGTGATCCGCGACATGATCTCCCACGCGGCCCTTATC
GTCTCCCACATCCAACTCTTCGACGAATCCCTCGACATGGCCCTGGATCTGGCGGGGCGAATCGACGTGATCCTTACCCT
CGACGAAATCAACAAGGCGATCTCGTCGTCCCTTTCCAGCGACAAGGTCCTGGGAACCGCCATGGAGCATGTGGAGCGGA
TAACGGGGTGCGAATTCGTGGCGATCCTCCAGGTGGAGGGGAGTAAAATGGCGATCATGGCATCCCACGCCGGAGAGCTT
CCGGTCCCCGACATTCTCCGCGCCGGTTCACGACTCCCCCGGGGGCGATGCGCCGCGTGGAATGCCCGTCGCAACGGACG
CAGCACGAGCGTCGTCTTCATGGAGAAAACCGAGGGGATGCCCCCCGTGGATCAGGCACTCTACTCCCTTGGCATCCGGT
CGGTTCTGGCCATTCCGCTGGTGGTCCGGAATGAGGTAAAGGGGGTACTCCTTCTGGGGGACACCGAGGCGGGGAAATTC
GCCCGGGGCGAGACCTTCACCATCGAGAAGATCGCATCCCAGATGGCGGTGGCTCTGGAAAACGCCCGGCTCTACGAAGA
CATGCGGAGCCTCTTCATCAACACCGTGGCGAGCCTCGCCAACGCCATCGATGCCAAGAGCCCCTGGACCAAGGGGCACT
CGGAGCGGGTCATGCACATCGCGGCCCGCATCGCGAAGGAAATGGGGTTTTCCGAACAGGAGGTGGAGAAGGTGCGGCTC
GGCGGCCTCCTCCACGACATCGGCAAGATCGGGGTAATCGAGGCGGTCCTGGAAAAACCGGCGGTCCTCTCCGACGACGA
GTTCCCCCCGCTTCGGGCCCACCCGGAGAAGGGGGTTGCGATTCTCTCTCCCATCGCCCAGTTGAATGACGTTCTCCCCG
CCATCCTCCACCACCACGAGCGCTATGATGGCAAAGGCTATCCCAAGGGGCTCAAGGGTGAGGAAATCCCCCTCTCGGCA
CGGATCGTTTCGGTTGCCGACTCCTTTGACGCCATGGTGTCGGAGCGCCCCTACAAGAAAGGGTATACCATCGGCGAGGC
CATTGCCGAGTTGCGCAGGGAGGCGGGGAGACAGTTCGACCCGAAGGTGGTGGAGTGCTTCTGCCGTTACCTTGAACGGA
CCATGGGGAGGGAACTCTCCGGAGACTTTCCGGAGGCGTTCAAGAAGGTTGCGGGAGGGTAG

Upstream 100 bases:

>100_bases
TCGGGCGCCACAACAACAGAGGGGGATAGTAATAAAAAAACCTATTTTTGGCAAGACATATGGGGTATTTGGTGGCAAAC
TACTCGGAGGGGTAATCACC

Downstream 100 bases:

>100_bases
CCCTCGCCCTTCATTGCCGGACCTCCTCCCGAAGCCGATCCTCGATGGCGGCAAGGCGCCGGTCGATGGATTCCAGGAGC
ACATGGTTCTGTTCCACCTT

Product: metal dependent phosphohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 553; Mature: 553

Protein sequence:

>553_residues
MIDTFNAVIEGSERLSGLADVDEVVKDLSRLLKRLVKSRWIAVYFFDRERRDFAPARSYGLPARFVPIFRDMPLVPDKIP
LLKGLLQKKQHLLLSDPSVSHLIPQKLRKLLRNLTLLAVPMVARNQVIGAVFVARARELPPFSPDEVAVIRDMISHAALI
VSHIQLFDESLDMALDLAGRIDVILTLDEINKAISSSLSSDKVLGTAMEHVERITGCEFVAILQVEGSKMAIMASHAGEL
PVPDILRAGSRLPRGRCAAWNARRNGRSTSVVFMEKTEGMPPVDQALYSLGIRSVLAIPLVVRNEVKGVLLLGDTEAGKF
ARGETFTIEKIASQMAVALENARLYEDMRSLFINTVASLANAIDAKSPWTKGHSERVMHIAARIAKEMGFSEQEVEKVRL
GGLLHDIGKIGVIEAVLEKPAVLSDDEFPPLRAHPEKGVAILSPIAQLNDVLPAILHHHERYDGKGYPKGLKGEEIPLSA
RIVSVADSFDAMVSERPYKKGYTIGEAIAELRREAGRQFDPKVVECFCRYLERTMGRELSGDFPEAFKKVAGG

Sequences:

>Translated_553_residues
MIDTFNAVIEGSERLSGLADVDEVVKDLSRLLKRLVKSRWIAVYFFDRERRDFAPARSYGLPARFVPIFRDMPLVPDKIP
LLKGLLQKKQHLLLSDPSVSHLIPQKLRKLLRNLTLLAVPMVARNQVIGAVFVARARELPPFSPDEVAVIRDMISHAALI
VSHIQLFDESLDMALDLAGRIDVILTLDEINKAISSSLSSDKVLGTAMEHVERITGCEFVAILQVEGSKMAIMASHAGEL
PVPDILRAGSRLPRGRCAAWNARRNGRSTSVVFMEKTEGMPPVDQALYSLGIRSVLAIPLVVRNEVKGVLLLGDTEAGKF
ARGETFTIEKIASQMAVALENARLYEDMRSLFINTVASLANAIDAKSPWTKGHSERVMHIAARIAKEMGFSEQEVEKVRL
GGLLHDIGKIGVIEAVLEKPAVLSDDEFPPLRAHPEKGVAILSPIAQLNDVLPAILHHHERYDGKGYPKGLKGEEIPLSA
RIVSVADSFDAMVSERPYKKGYTIGEAIAELRREAGRQFDPKVVECFCRYLERTMGRELSGDFPEAFKKVAGG
>Mature_553_residues
MIDTFNAVIEGSERLSGLADVDEVVKDLSRLLKRLVKSRWIAVYFFDRERRDFAPARSYGLPARFVPIFRDMPLVPDKIP
LLKGLLQKKQHLLLSDPSVSHLIPQKLRKLLRNLTLLAVPMVARNQVIGAVFVARARELPPFSPDEVAVIRDMISHAALI
VSHIQLFDESLDMALDLAGRIDVILTLDEINKAISSSLSSDKVLGTAMEHVERITGCEFVAILQVEGSKMAIMASHAGEL
PVPDILRAGSRLPRGRCAAWNARRNGRSTSVVFMEKTEGMPPVDQALYSLGIRSVLAIPLVVRNEVKGVLLLGDTEAGKF
ARGETFTIEKIASQMAVALENARLYEDMRSLFINTVASLANAIDAKSPWTKGHSERVMHIAARIAKEMGFSEQEVEKVRL
GGLLHDIGKIGVIEAVLEKPAVLSDDEFPPLRAHPEKGVAILSPIAQLNDVLPAILHHHERYDGKGYPKGLKGEEIPLSA
RIVSVADSFDAMVSERPYKKGYTIGEAIAELRREAGRQFDPKVVECFCRYLERTMGRELSGDFPEAFKKVAGG

Specific function: Positively regulates the synthesis of extracellular enzymes and extracellular polysaccharides. The cell-cell signaling system encoded by rpf genes is required for full virulence and is implicated in regulation of the formation and dispersal of biofilms [H

COG id: COG2206

COG function: function code T; HD-GYP domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR003607
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 61080; Mature: 61080

Theoretical pI: Translated: 8.32; Mature: 8.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDTFNAVIEGSERLSGLADVDEVVKDLSRLLKRLVKSRWIAVYFFDRERRDFAPARSYG
CCCCHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCHHHCC
LPARFVPIFRDMPLVPDKIPLLKGLLQKKQHLLLSDPSVSHLIPQKLRKLLRNLTLLAVP
CCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHH
MVARNQVIGAVFVARARELPPFSPDEVAVIRDMISHAALIVSHIQLFDESLDMALDLAGR
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IDVILTLDEINKAISSSLSSDKVLGTAMEHVERITGCEFVAILQVEGSKMAIMASHAGEL
EEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEEEECCCCCC
PVPDILRAGSRLPRGRCAAWNARRNGRSTSVVFMEKTEGMPPVDQALYSLGIRSVLAIPL
CCHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
VVRNEVKGVLLLGDTEAGKFARGETFTIEKIASQMAVALENARLYEDMRSLFINTVASLA
HHHCCCCEEEEEECCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NAIDAKSPWTKGHSERVMHIAARIAKEMGFSEQEVEKVRLGGLLHDIGKIGVIEAVLEKP
HHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AVLSDDEFPPLRAHPEKGVAILSPIAQLNDVLPAILHHHERYDGKGYPKGLKGEEIPLSA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHH
RIVSVADSFDAMVSERPYKKGYTIGEAIAELRREAGRQFDPKVVECFCRYLERTMGRELS
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCC
GDFPEAFKKVAGG
CCHHHHHHHHCCC
>Mature Secondary Structure
MIDTFNAVIEGSERLSGLADVDEVVKDLSRLLKRLVKSRWIAVYFFDRERRDFAPARSYG
CCCCHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCHHHCC
LPARFVPIFRDMPLVPDKIPLLKGLLQKKQHLLLSDPSVSHLIPQKLRKLLRNLTLLAVP
CCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHH
MVARNQVIGAVFVARARELPPFSPDEVAVIRDMISHAALIVSHIQLFDESLDMALDLAGR
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IDVILTLDEINKAISSSLSSDKVLGTAMEHVERITGCEFVAILQVEGSKMAIMASHAGEL
EEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEEEECCCCCC
PVPDILRAGSRLPRGRCAAWNARRNGRSTSVVFMEKTEGMPPVDQALYSLGIRSVLAIPL
CCHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
VVRNEVKGVLLLGDTEAGKFARGETFTIEKIASQMAVALENARLYEDMRSLFINTVASLA
HHHCCCCEEEEEECCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NAIDAKSPWTKGHSERVMHIAARIAKEMGFSEQEVEKVRLGGLLHDIGKIGVIEAVLEKP
HHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AVLSDDEFPPLRAHPEKGVAILSPIAQLNDVLPAILHHHERYDGKGYPKGLKGEEIPLSA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHH
RIVSVADSFDAMVSERPYKKGYTIGEAIAELRREAGRQFDPKVVECFCRYLERTMGRELS
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCC
GDFPEAFKKVAGG
CCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11123673 [H]