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The map label for this gene is mat [H]

Identifier: 78223746

GI number: 78223746

Start: 2894375

End: 2895577

Strand: Direct

Name: mat [H]

Synonym: Gmet_2549

Alternate gene names: 78223746

Gene position: 2894375-2895577 (Clockwise)

Preceding gene: 78223745

Following gene: 78223756

Centisome position: 72.41

GC content: 62.51

Gene sequence:

>1203_bases
ATGATAACCATCGAAGCATTCAAGGGGAACTCTGTTCAGGAGCAGCAGGTGGAAATCGTGGAGCGGAAGGGGAAAGGCCA
TCCCGACTTCATCTGTGACGCGGCCATGGACGCCGTCTCCGTGGCCCTGTCCCAGGAGTATATCCGGCAGTTCGGCCGCA
TTCTCCACCACAACATCGACAAGAGCCTCCTTGCGGCGGGAAGCGTGGAAAAGCGCTTCGGCGGCGGCCGGGTAATCCGT
CCCATGGAGCTCATCATCGGTGACCGGGCCACGTTTTCCGTGGGAGATCGGCAGATTCCGGTGACGGAGATCGCCCTGGG
CGCCGCCCGTGAGTGGTTCAGAAAGAACCTCCGTTTCGTGGACCCGGAGCTGCACGTAAATTTCCGTGTGGTGCTGGCGC
CGGGATCTGAAGAACTCACCGACATCTTCGCCCGGCCGGGGGAAGTCATGGCAGCCAACGACACCTCGGCAGCCGTGGGC
TACTGGCCCCTCTCGCCGACGGAACTGGCGGTCCTCGCCCTGGAACAGCACCTGAATTCCCGGGAGTTCAAGGAGCACTT
TCCCGAAACCGGCGAAGACATCAAGGTCATGGGCCTACGCTCGGGGAAAGATCTCGAGCTGACCGTGGCAATGCCGTTCC
TGGCGCGGTTCATCGAATCAGAAGGGGAATACTTCGCCAGAAAGGGCGTGGTTGAGAGAGAGATTGGTGAGTTTCTCACG
GGACTCCCCGGTTTCGGCCGAAAAGGGGTTCGCCTCAACGCCCTTGACGAACCGGGACGGGGACTTGGAGGCGTCTACCT
GAGCCTCCTGGGCACCTCGGCGGAAGACGCCGATTCGGGCCAGGTTGGTCGCGGCAACCGGGTCAACGGGATCATTGCCC
TGGGGCGGCCCCTCGGCACCGAGGCCGCCGCCGGCAAGAACCCGGTGAGCCATGTGGGAAAAATCTACAACATCCTTGCC
CACCGGCTCGCCCAGGAGATTTGCGAGGAACTGGAGGGGGTCAGAGAGGCCCACGTTCTCTTGTTGAGCCGGATCGGCAC
CCCCATCGACCGCCCCCGGATGGCGGCGGCCCAGCTGCTGCTGGAAAAGGGAATTCGGCTCGGCAATGTTTCGGCAAAGG
CCGAGGAGATCATCGGCCAGAGGCTGGCTGGTATCAACGGATTCTGCATGGAACTGGCGGCTGGCCGCTATCCGGTCTGC
TGA

Upstream 100 bases:

>100_bases
TTCACGGCTTCAAGAGCCGTCCCCGGGCAGCGGGGACGGCTTTCTTGTTTCCAGTGTCCGCCTCCGTGAAATTGCGCGCC
GGTATGATACAGTGTAATCC

Downstream 100 bases:

>100_bases
AGGGAATCACATCAGTAAGGACAAAAGCACCTGGACAATGAGTATCTTCCCGATGGTTGCGACCGGGTAGACCGAGGCGT
AGCCGATGTTGGGGAGATCG

Product: S-adenosylmethionine synthetase

Products: NA

Alternate protein names: AdoMet synthase; Methionine adenosyltransferase [H]

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MITIEAFKGNSVQEQQVEIVERKGKGHPDFICDAAMDAVSVALSQEYIRQFGRILHHNIDKSLLAAGSVEKRFGGGRVIR
PMELIIGDRATFSVGDRQIPVTEIALGAAREWFRKNLRFVDPELHVNFRVVLAPGSEELTDIFARPGEVMAANDTSAAVG
YWPLSPTELAVLALEQHLNSREFKEHFPETGEDIKVMGLRSGKDLELTVAMPFLARFIESEGEYFARKGVVEREIGEFLT
GLPGFGRKGVRLNALDEPGRGLGGVYLSLLGTSAEDADSGQVGRGNRVNGIIALGRPLGTEAAAGKNPVSHVGKIYNILA
HRLAQEICEELEGVREAHVLLLSRIGTPIDRPRMAAAQLLLEKGIRLGNVSAKAEEIIGQRLAGINGFCMELAAGRYPVC

Sequences:

>Translated_400_residues
MITIEAFKGNSVQEQQVEIVERKGKGHPDFICDAAMDAVSVALSQEYIRQFGRILHHNIDKSLLAAGSVEKRFGGGRVIR
PMELIIGDRATFSVGDRQIPVTEIALGAAREWFRKNLRFVDPELHVNFRVVLAPGSEELTDIFARPGEVMAANDTSAAVG
YWPLSPTELAVLALEQHLNSREFKEHFPETGEDIKVMGLRSGKDLELTVAMPFLARFIESEGEYFARKGVVEREIGEFLT
GLPGFGRKGVRLNALDEPGRGLGGVYLSLLGTSAEDADSGQVGRGNRVNGIIALGRPLGTEAAAGKNPVSHVGKIYNILA
HRLAQEICEELEGVREAHVLLLSRIGTPIDRPRMAAAQLLLEKGIRLGNVSAKAEEIIGQRLAGINGFCMELAAGRYPVC
>Mature_400_residues
MITIEAFKGNSVQEQQVEIVERKGKGHPDFICDAAMDAVSVALSQEYIRQFGRILHHNIDKSLLAAGSVEKRFGGGRVIR
PMELIIGDRATFSVGDRQIPVTEIALGAAREWFRKNLRFVDPELHVNFRVVLAPGSEELTDIFARPGEVMAANDTSAAVG
YWPLSPTELAVLALEQHLNSREFKEHFPETGEDIKVMGLRSGKDLELTVAMPFLARFIESEGEYFARKGVVEREIGEFLT
GLPGFGRKGVRLNALDEPGRGLGGVYLSLLGTSAEDADSGQVGRGNRVNGIIALGRPLGTEAAAGKNPVSHVGKIYNILA
HRLAQEICEELEGVREAHVLLLSRIGTPIDRPRMAAAQLLLEKGIRLGNVSAKAEEIIGQRLAGINGFCMELAAGRYPVC

Specific function: Catalyzes the formation of S-adenosylmethionine from methionine and ATP [H]

COG id: COG1812

COG function: function code E; Archaeal S-adenosylmethionine synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AdoMet synthase 2 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002795
- ProDom:   PD011777 [H]

Pfam domain/function: PF01941 AdoMet_Synthase [H]

EC number: =2.5.1.6 [H]

Molecular weight: Translated: 43526; Mature: 43526

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITIEAFKGNSVQEQQVEIVERKGKGHPDFICDAAMDAVSVALSQEYIRQFGRILHHNID
CEEEEECCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
KSLLAAGSVEKRFGGGRVIRPMELIIGDRATFSVGDRQIPVTEIALGAAREWFRKNLRFV
HHHHHCCCHHHHCCCCCEECHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCEE
DPELHVNFRVVLAPGSEELTDIFARPGEVMAANDTSAAVGYWPLSPTELAVLALEQHLNS
CCCEEEEEEEEECCCCHHHHHHHCCCCCEEEECCCCCEEEECCCCHHHHHHHHHHHHCCH
REFKEHFPETGEDIKVMGLRSGKDLELTVAMPFLARFIESEGEYFARKGVVEREIGEFLT
HHHHHHCCCCCCCEEEEEECCCCCEEEEEHHHHHHHHHHCCCHHHHHHCHHHHHHHHHHH
GLPGFGRKGVRLNALDEPGRGLGGVYLSLLGTSAEDADSGQVGRGNRVNGIIALGRPLGT
CCCCCCCCCCEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCC
EAAAGKNPVSHVGKIYNILAHRLAQEICEELEGVREAHVLLLSRIGTPIDRPRMAAAQLL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
LEKGIRLGNVSAKAEEIIGQRLAGINGFCMELAAGRYPVC
HHCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCC
>Mature Secondary Structure
MITIEAFKGNSVQEQQVEIVERKGKGHPDFICDAAMDAVSVALSQEYIRQFGRILHHNID
CEEEEECCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
KSLLAAGSVEKRFGGGRVIRPMELIIGDRATFSVGDRQIPVTEIALGAAREWFRKNLRFV
HHHHHCCCHHHHCCCCCEECHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCEE
DPELHVNFRVVLAPGSEELTDIFARPGEVMAANDTSAAVGYWPLSPTELAVLALEQHLNS
CCCEEEEEEEEECCCCHHHHHHHCCCCCEEEECCCCCEEEECCCCHHHHHHHHHHHHCCH
REFKEHFPETGEDIKVMGLRSGKDLELTVAMPFLARFIESEGEYFARKGVVEREIGEFLT
HHHHHHCCCCCCCEEEEEECCCCCEEEEEHHHHHHHHHHCCCHHHHHHCHHHHHHHHHHH
GLPGFGRKGVRLNALDEPGRGLGGVYLSLLGTSAEDADSGQVGRGNRVNGIIALGRPLGT
CCCCCCCCCCEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCC
EAAAGKNPVSHVGKIYNILAHRLAQEICEELEGVREAHVLLLSRIGTPIDRPRMAAAQLL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
LEKGIRLGNVSAKAEEIIGQRLAGINGFCMELAAGRYPVC
HHCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]