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The map label for this gene is hflX [H]

Identifier: 78223754

GI number: 78223754

Start: 2902977

End: 2904527

Strand: Reverse

Name: hflX [H]

Synonym: Gmet_2557

Alternate gene names: 78223754

Gene position: 2904527-2902977 (Counterclockwise)

Preceding gene: 78223755

Following gene: 78223753

Centisome position: 72.66

GC content: 63.89

Gene sequence:

>1551_bases
ATGGTGGAGATCTCGCGGGAGATCCGGCGGCAGATCGGTGTTCTCATCGACCGTCACGGGGCCGTGGAGTATGTCATTAT
CGGCGACGAGAAAGGGATATTCATCCCCGAACTCTCCGATTACCCTTTGGGGCGCCGCCTGTTGCGGGGGCTCCGCTACA
TCCACACCCACCTCAAGGGGGAGTCCTTCTCCGAGGACGACCTGACCGACCTGGCGCTCCTGCGCTTCGACCTCATGGCG
ATCCTCCAGATTCACCCGGACGACCGCCGGGTCGCTATCCAGACCGCCTCCCTCACCCCCACCGCCGGCGCCGCTCATCC
CTACCGGGTGGAGGCGTCCGAACCCCTTGCCACCTTCCGCATGGATTTCGGTTCCTCGGTATCGCACCTGGAGCGGGAGC
TGGAGAAGGCGGTGGCCACCGAGGCGCGCGAGGTTGCTGCTTCGGGAGAGCGGGCCATTCTCATCTCGGTCACGAAAGAG
TCCCGCGAGGAGGCCGAGGACTCCCTGGAAGAGCTCAAGGAACTGGCCCGCACCGCCGGGGTTGCCGTCCTCGACGTGGT
GATCCAACGCCCCCGGCAGTTCAACCCCCGCTACCTCATGGGGGAGGGGAAAATGCGGGAGGTGGTGATCCGGGCGCTCC
AGTTGGGGGCGACGATCCTCATCTTCGACCAGGAGCTTTCCCCGGCCCAGGTTCGCTCCATCTCCGAGATGACCGAACTC
AAGGTCATCGACCGGAGCCAGCTCATCCTCGACATCTTCGCCCGCCGGGCCACGAGCCTCGACGGAAAGGTGCAGGTGGA
GCTGGCCCAGCTCAAATACATCCTCCCCCGCCTCACCGGGCGGGGAGTGCAGATGTCGCGCCTCATGGGGGGGATCGGCG
GCAGGGGCCCCGGCGAAACGAAGCTGGAGACGGATCGGCGGCGAATCCGCGATCGGATCGCGAAGCTGGAGCGGGAGCTT
GAAGAGTTGTCGCGGGGACGCCAGCAGCGCCGCCAGAAACGGGTGCGGGCCGGGCTCCCCATCGTCTCCATCGTCGGCTA
CACCAACGCCGGGAAATCGACCCTTCTCAATGCCCTCACCCGGAGCCACGTCTTCACCGAAAACCTCCTCTTCGCCACCC
TCGACACCTCGACCCGGCGGCTCCGCTTCCCCCGGGAACGGGAGGTGATCATCACTGATACGGTCGGCTTTATCCGCTCC
CTTCCCAAGTCCCTCATGGGAGCTTTCAAGGCTACCCTTGAGGAGCTGCAGGACGCTGACCTCCTGCTCCATCTGGTGGA
CTGTACCAATCCCCGCGTGGAGGAGCAGATCCACCAGGTGGAGACGATCCTGGAGGAACTGGACCTGGGGGACAAGCAAC
GGCTCATGGTCTTCAACAAAGTAGATATTCTACCGGAGTTGAAGAAAAAGAGCCCCCTCGGCTTCATGAAGGTCCGCCAG
CTATCCCGGCGCTTCAACGCCATCACCGTCAGCGCCACGAATCCGTCAAGCCTTGAGTCGCTTCTCCAGGAAATGGAGCG
CCGTTTCTGGCCTTCATCCCCCCAATCTTGA

Upstream 100 bases:

>100_bases
CCTCATCGGCCTGAAGCCGAATCAGATCGCATCCCTGGAGCGGCTCTACCGGCGCCGCGTCCCCCCCGACGAGCTCATCA
CCGCCGAGTTGGCAGGGCGG

Downstream 100 bases:

>100_bases
CACCAATGCCCCGATTCCCTATAATGCGGGTTCCGTCCGGCACTACTTCCCACATCCGGTCGTTATGGCCATGCGTGGAA
GGTTTCTCATGAAAAAAGCT

Product: small GTP-binding protein domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 516; Mature: 516

Protein sequence:

>516_residues
MVEISREIRRQIGVLIDRHGAVEYVIIGDEKGIFIPELSDYPLGRRLLRGLRYIHTHLKGESFSEDDLTDLALLRFDLMA
ILQIHPDDRRVAIQTASLTPTAGAAHPYRVEASEPLATFRMDFGSSVSHLERELEKAVATEAREVAASGERAILISVTKE
SREEAEDSLEELKELARTAGVAVLDVVIQRPRQFNPRYLMGEGKMREVVIRALQLGATILIFDQELSPAQVRSISEMTEL
KVIDRSQLILDIFARRATSLDGKVQVELAQLKYILPRLTGRGVQMSRLMGGIGGRGPGETKLETDRRRIRDRIAKLEREL
EELSRGRQQRRQKRVRAGLPIVSIVGYTNAGKSTLLNALTRSHVFTENLLFATLDTSTRRLRFPREREVIITDTVGFIRS
LPKSLMGAFKATLEELQDADLLLHLVDCTNPRVEEQIHQVETILEELDLGDKQRLMVFNKVDILPELKKKSPLGFMKVRQ
LSRRFNAITVSATNPSSLESLLQEMERRFWPSSPQS

Sequences:

>Translated_516_residues
MVEISREIRRQIGVLIDRHGAVEYVIIGDEKGIFIPELSDYPLGRRLLRGLRYIHTHLKGESFSEDDLTDLALLRFDLMA
ILQIHPDDRRVAIQTASLTPTAGAAHPYRVEASEPLATFRMDFGSSVSHLERELEKAVATEAREVAASGERAILISVTKE
SREEAEDSLEELKELARTAGVAVLDVVIQRPRQFNPRYLMGEGKMREVVIRALQLGATILIFDQELSPAQVRSISEMTEL
KVIDRSQLILDIFARRATSLDGKVQVELAQLKYILPRLTGRGVQMSRLMGGIGGRGPGETKLETDRRRIRDRIAKLEREL
EELSRGRQQRRQKRVRAGLPIVSIVGYTNAGKSTLLNALTRSHVFTENLLFATLDTSTRRLRFPREREVIITDTVGFIRS
LPKSLMGAFKATLEELQDADLLLHLVDCTNPRVEEQIHQVETILEELDLGDKQRLMVFNKVDILPELKKKSPLGFMKVRQ
LSRRFNAITVSATNPSSLESLLQEMERRFWPSSPQS
>Mature_516_residues
MVEISREIRRQIGVLIDRHGAVEYVIIGDEKGIFIPELSDYPLGRRLLRGLRYIHTHLKGESFSEDDLTDLALLRFDLMA
ILQIHPDDRRVAIQTASLTPTAGAAHPYRVEASEPLATFRMDFGSSVSHLERELEKAVATEAREVAASGERAILISVTKE
SREEAEDSLEELKELARTAGVAVLDVVIQRPRQFNPRYLMGEGKMREVVIRALQLGATILIFDQELSPAQVRSISEMTEL
KVIDRSQLILDIFARRATSLDGKVQVELAQLKYILPRLTGRGVQMSRLMGGIGGRGPGETKLETDRRRIRDRIAKLEREL
EELSRGRQQRRQKRVRAGLPIVSIVGYTNAGKSTLLNALTRSHVFTENLLFATLDTSTRRLRFPREREVIITDTVGFIRS
LPKSLMGAFKATLEELQDADLLLHLVDCTNPRVEEQIHQVETILEELDLGDKQRLMVFNKVDILPELKKKSPLGFMKVRQ
LSRRFNAITVSATNPSSLESLLQEMERRFWPSSPQS

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133116, Length=229, Percent_Identity=33.1877729257642, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI310133118, Length=239, Percent_Identity=32.6359832635983, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI310124269, Length=215, Percent_Identity=33.953488372093, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI310124267, Length=215, Percent_Identity=33.953488372093, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI310124171, Length=215, Percent_Identity=33.953488372093, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI310124169, Length=215, Percent_Identity=33.953488372093, Blast_Score=119, Evalue=6e-27,
Organism=Escherichia coli, GI1790615, Length=362, Percent_Identity=43.0939226519337, Blast_Score=294, Evalue=1e-80,
Organism=Caenorhabditis elegans, GI17561038, Length=316, Percent_Identity=28.4810126582279, Blast_Score=118, Evalue=8e-27,
Organism=Drosophila melanogaster, GI24650079, Length=291, Percent_Identity=35.0515463917526, Blast_Score=123, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 58439; Mature: 58439

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEISREIRRQIGVLIDRHGAVEYVIIGDEKGIFIPELSDYPLGRRLLRGLRYIHTHLKG
CCCCHHHHHHHHHHEEECCCCEEEEEEECCCCEECCCCCCCCHHHHHHHHHHHHHHHHCC
ESFSEDDLTDLALLRFDLMAILQIHPDDRRVAIQTASLTPTAGAAHPYRVEASEPLATFR
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCEEECCCCCHHHHH
MDFGSSVSHLERELEKAVATEAREVAASGERAILISVTKESREEAEDSLEELKELARTAG
HCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHH
VAVLDVVIQRPRQFNPRYLMGEGKMREVVIRALQLGATILIFDQELSPAQVRSISEMTEL
HHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHH
KVIDRSQLILDIFARRATSLDGKVQVELAQLKYILPRLTGRGVQMSRLMGGIGGRGPGET
HHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCC
KLETDRRRIRDRIAKLERELEELSRGRQQRRQKRVRAGLPIVSIVGYTNAGKSTLLNALT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHH
RSHVFTENLLFATLDTSTRRLRFPREREVIITDTVGFIRSLPKSLMGAFKATLEELQDAD
HHHHHHHHHEEEEECCCHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCHH
LLLHLVDCTNPRVEEQIHQVETILEELDLGDKQRLMVFNKVDILPELKKKSPLGFMKVRQ
HHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHEEEEHHHHHHHHHHHCCCCHHHHHHH
LSRRFNAITVSATNPSSLESLLQEMERRFWPSSPQS
HHHHCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MVEISREIRRQIGVLIDRHGAVEYVIIGDEKGIFIPELSDYPLGRRLLRGLRYIHTHLKG
CCCCHHHHHHHHHHEEECCCCEEEEEEECCCCEECCCCCCCCHHHHHHHHHHHHHHHHCC
ESFSEDDLTDLALLRFDLMAILQIHPDDRRVAIQTASLTPTAGAAHPYRVEASEPLATFR
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCEEECCCCCHHHHH
MDFGSSVSHLERELEKAVATEAREVAASGERAILISVTKESREEAEDSLEELKELARTAG
HCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHH
VAVLDVVIQRPRQFNPRYLMGEGKMREVVIRALQLGATILIFDQELSPAQVRSISEMTEL
HHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHH
KVIDRSQLILDIFARRATSLDGKVQVELAQLKYILPRLTGRGVQMSRLMGGIGGRGPGET
HHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCC
KLETDRRRIRDRIAKLERELEELSRGRQQRRQKRVRAGLPIVSIVGYTNAGKSTLLNALT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHH
RSHVFTENLLFATLDTSTRRLRFPREREVIITDTVGFIRSLPKSLMGAFKATLEELQDAD
HHHHHHHHHEEEEECCCHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCHH
LLLHLVDCTNPRVEEQIHQVETILEELDLGDKQRLMVFNKVDILPELKKKSPLGFMKVRQ
HHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHEEEEHHHHHHHHHHHCCCCHHHHHHH
LSRRFNAITVSATNPSSLESLLQEMERRFWPSSPQS
HHHHCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]