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The map label for this gene is trpD

Identifier: 78223696

GI number: 78223696

Start: 2837470

End: 2838522

Strand: Reverse

Name: trpD

Synonym: Gmet_2495

Alternate gene names: 78223696

Gene position: 2838522-2837470 (Counterclockwise)

Preceding gene: 78223697

Following gene: 78223695

Centisome position: 71.01

GC content: 65.62

Gene sequence:

>1053_bases
ATGATCAAAAAAGCAATTGCAAAGGTAGTTGAGCGCATCGACCTCACGGAAGCGGAGATGATCGAGGTCATGGACCAGAT
CATGTCCGGCGAGGCCACCCCGGCCCAGATCGCTTCCTTCATCACCGCCCTCCGAATGAAGGGGGAGACGGTGGAGGAGA
TCACCGGCGCAGCCCGAGTCATGCGGGATCGGGCCACCCCCATCCGGGTCGGCAAGGGGGTCCTCGATATCGACCGGGAT
GACATCAACATCGATCAGGAGACGATCCTGGACGTGGTCGGCACCGGGGGGGACGGCACCAACACCTTCAATATCTCCAC
CACCGTCTCCTTCGTGGTGGCATCCTGCGGGGTGAAGGTGGCCAAGCACGGCAACCGGGCGGTTTCGTCCGCCTGCGGGA
GTGCCGACGTCCTGGAGTCCCTGGGGGTCAGCCTGGACGTGACCCCGGAGACGGTGGAGAACGCCATCGCGAGGATCGGC
ATCGGCTTCCTCTTCGCCCCGGCCCTCCACGGCGCCATGAAACACGCCATCGGCCCCCGGAAGGAGATCGGCATCCGGAC
CATCTTCAATATCCTCGGGCCCCTCACGAACCCGGCCGGCGCCGACTGCCAGGTCCTCGGCGTTTACCGGGAGGATCTCG
TGGAGCCCCTGGCCCATGTCCTTCACAAGCTTGGCTGCAAGCGCGGCTTTGTGGTCTTCGGCATGGACGGCATGGACGAG
ATTACCCTTACCCGTGAGACCCGCGTTGCCGAGGTGACCCGGGAGGGGGTGACGGTGCGGACCATCACGCCGGAGGAGTT
CGGCTTTGCCTCCTGTCCTCCCGGTGATCTCCGGGGGGGCGACGCCGCCGGCAACGCTCGCATCGTTCGCAGCATCCTGG
ACGGGGCCACGGGGCCCAGGCGGGACGTGGTGCTCCTGAACGCCGCCTATGCCCTCGTGGCCGCCGGCAAGGCCACGGAC
CCGGCCGAGGGGATCCGTCTCGCCGCCGAGGCCATCGATTCGGGCCGCGCCCTGGCAAAGCTGGAAGAGCTGATTGCATT
GACAAATGAATAA

Upstream 100 bases:

>100_bases
CCCACAGGGAGCTGCCGATCTGGGGGGTCCAGTTCCATCCCGAGTCGATCCTCACCGAGGGGGGGATGGACATCCTCAAG
AATTTCCTGGAGATGACACA

Downstream 100 bases:

>100_bases
TGTTGTAGGGGCGGACTGTGTCCGCCCGATTCTGAAATTTGGAAACCCACTATGCCCACAACCCCTGACATCCTGAAAAA
GATAGTCGAACACAAGCGCC

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MIKKAIAKVVERIDLTEAEMIEVMDQIMSGEATPAQIASFITALRMKGETVEEITGAARVMRDRATPIRVGKGVLDIDRD
DINIDQETILDVVGTGGDGTNTFNISTTVSFVVASCGVKVAKHGNRAVSSACGSADVLESLGVSLDVTPETVENAIARIG
IGFLFAPALHGAMKHAIGPRKEIGIRTIFNILGPLTNPAGADCQVLGVYREDLVEPLAHVLHKLGCKRGFVVFGMDGMDE
ITLTRETRVAEVTREGVTVRTITPEEFGFASCPPGDLRGGDAAGNARIVRSILDGATGPRRDVVLLNAAYALVAAGKATD
PAEGIRLAAEAIDSGRALAKLEELIALTNE

Sequences:

>Translated_350_residues
MIKKAIAKVVERIDLTEAEMIEVMDQIMSGEATPAQIASFITALRMKGETVEEITGAARVMRDRATPIRVGKGVLDIDRD
DINIDQETILDVVGTGGDGTNTFNISTTVSFVVASCGVKVAKHGNRAVSSACGSADVLESLGVSLDVTPETVENAIARIG
IGFLFAPALHGAMKHAIGPRKEIGIRTIFNILGPLTNPAGADCQVLGVYREDLVEPLAHVLHKLGCKRGFVVFGMDGMDE
ITLTRETRVAEVTREGVTVRTITPEEFGFASCPPGDLRGGDAAGNARIVRSILDGATGPRRDVVLLNAAYALVAAGKATD
PAEGIRLAAEAIDSGRALAKLEELIALTNE
>Mature_350_residues
MIKKAIAKVVERIDLTEAEMIEVMDQIMSGEATPAQIASFITALRMKGETVEEITGAARVMRDRATPIRVGKGVLDIDRD
DINIDQETILDVVGTGGDGTNTFNISTTVSFVVASCGVKVAKHGNRAVSSACGSADVLESLGVSLDVTPETVENAIARIG
IGFLFAPALHGAMKHAIGPRKEIGIRTIFNILGPLTNPAGADCQVLGVYREDLVEPLAHVLHKLGCKRGFVVFGMDGMDE
ITLTRETRVAEVTREGVTVRTITPEEFGFASCPPGDLRGGDAAGNARIVRSILDGATGPRRDVVLLNAAYALVAAGKATD
PAEGIRLAAEAIDSGRALAKLEELIALTNE

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=294, Percent_Identity=37.4149659863946, Blast_Score=193, Evalue=1e-50,
Organism=Saccharomyces cerevisiae, GI6320561, Length=329, Percent_Identity=32.5227963525836, Blast_Score=143, Evalue=5e-35,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_GEOMG (Q39SQ6)

Other databases:

- EMBL:   CP000148
- RefSeq:   YP_385443.1
- ProteinModelPortal:   Q39SQ6
- SMR:   Q39SQ6
- STRING:   Q39SQ6
- GeneID:   3740171
- GenomeReviews:   CP000148_GR
- KEGG:   gme:Gmet_2495
- NMPDR:   fig|269799.3.peg.2661
- eggNOG:   COG0547
- HOGENOM:   HBG559996
- OMA:   LGVYSPE
- PhylomeDB:   Q39SQ6
- ProtClustDB:   PRK00188
- BioCyc:   GMET269799:GMET_2495-MONOMER
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 36898; Mature: 36898

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKKAIAKVVERIDLTEAEMIEVMDQIMSGEATPAQIASFITALRMKGETVEEITGAARV
CCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
MRDRATPIRVGKGVLDIDRDDINIDQETILDVVGTGGDGTNTFNISTTVSFVVASCGVKV
HHHCCCCEECCCCEEECCCCCCCCCHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHCHHH
AKHGNRAVSSACGSADVLESLGVSLDVTPETVENAIARIGIGFLFAPALHGAMKHAIGPR
HHCCCHHHHHHCCCHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KEIGIRTIFNILGPLTNPAGADCQVLGVYREDLVEPLAHVLHKLGCKRGFVVFGMDGMDE
HHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCC
ITLTRETRVAEVTREGVTVRTITPEEFGFASCPPGDLRGGDAAGNARIVRSILDGATGPR
EEEEHHHHHHHHHHCCEEEEEECHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCC
RDVVLLNAAYALVAAGKATDPAEGIRLAAEAIDSGRALAKLEELIALTNE
CCEEEEEHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIKKAIAKVVERIDLTEAEMIEVMDQIMSGEATPAQIASFITALRMKGETVEEITGAARV
CCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
MRDRATPIRVGKGVLDIDRDDINIDQETILDVVGTGGDGTNTFNISTTVSFVVASCGVKV
HHHCCCCEECCCCEEECCCCCCCCCHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHCHHH
AKHGNRAVSSACGSADVLESLGVSLDVTPETVENAIARIGIGFLFAPALHGAMKHAIGPR
HHCCCHHHHHHCCCHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KEIGIRTIFNILGPLTNPAGADCQVLGVYREDLVEPLAHVLHKLGCKRGFVVFGMDGMDE
HHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCC
ITLTRETRVAEVTREGVTVRTITPEEFGFASCPPGDLRGGDAAGNARIVRSILDGATGPR
EEEEHHHHHHHHHHCCEEEEEECHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCC
RDVVLLNAAYALVAAGKATDPAEGIRLAAEAIDSGRALAKLEELIALTNE
CCEEEEEHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA