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The map label for this gene is trpG [H]

Identifier: 78223697

GI number: 78223697

Start: 2838519

End: 2839088

Strand: Reverse

Name: trpG [H]

Synonym: Gmet_2496

Alternate gene names: 78223697

Gene position: 2839088-2838519 (Counterclockwise)

Preceding gene: 78223698

Following gene: 78223696

Centisome position: 71.02

GC content: 63.51

Gene sequence:

>570_bases
ATGTTGCTCATGATCGACAATTACGACTCCTTCACCTACAACATCGTCCAGTACTTTGGCGAACTGGGGGAGGATGTGCG
GGTCTTCCGCAACGACGGCATTACCCTGGAGGAGATCGAACGGCTGGCGCCCGAGCGCCTCGTCATTTCCCCCGGCCCTT
GCTCCCCCGAGGAGGCGGGGATTTCCGTCGCCGCCATCCGCCACTTTGCCGGCAAGATCCCGATCCTCGGGGTCTGCCTC
GGCCATCAGTCAATCGGCGCCGCCTTCGGCGGGAAGGTGGTCCGCAGCTCCACCCTCATGCACGGCAAGACTTCCCCGAT
CCACCACAACGGCCAGGGGCTCTTCCGGGGGCTCCCCAATCCCTTCAATGCCACCCGATACCACTCGCTGGTGGTGGAGC
GGGCCACGTTCCCCGACTGCCTTGAGATCACCGCCTGGGTGGAGGAGGGGGAGGTCATGGGGCTCGCCCACAGGGAGCTG
CCGATCTGGGGGGTCCAGTTCCATCCCGAGTCGATCCTCACCGAGGGGGGGATGGACATCCTCAAGAATTTCCTGGAGAT
GACACAATGA

Upstream 100 bases:

>100_bases
GTGGCCGACTCGGACCCGGCCGCGGAATACCAGGAGACCGTCAACAAGGCCATGGCTGCGGTTAAGGCCATCGAGACCGC
GGAAAAGGGATTGGACTGAC

Downstream 100 bases:

>100_bases
TCAAAAAAGCAATTGCAAAGGTAGTTGAGCGCATCGACCTCACGGAAGCGGAGATGATCGAGGTCATGGACCAGATCATG
TCCGGCGAGGCCACCCCGGC

Product: anthranilate synthase component II

Products: NA

Alternate protein names: Glutamine amido-transferase [H]

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MLLMIDNYDSFTYNIVQYFGELGEDVRVFRNDGITLEEIERLAPERLVISPGPCSPEEAGISVAAIRHFAGKIPILGVCL
GHQSIGAAFGGKVVRSSTLMHGKTSPIHHNGQGLFRGLPNPFNATRYHSLVVERATFPDCLEITAWVEEGEVMGLAHREL
PIWGVQFHPESILTEGGMDILKNFLEMTQ

Sequences:

>Translated_189_residues
MLLMIDNYDSFTYNIVQYFGELGEDVRVFRNDGITLEEIERLAPERLVISPGPCSPEEAGISVAAIRHFAGKIPILGVCL
GHQSIGAAFGGKVVRSSTLMHGKTSPIHHNGQGLFRGLPNPFNATRYHSLVVERATFPDCLEITAWVEEGEVMGLAHREL
PIWGVQFHPESILTEGGMDILKNFLEMTQ
>Mature_189_residues
MLLMIDNYDSFTYNIVQYFGELGEDVRVFRNDGITLEEIERLAPERLVISPGPCSPEEAGISVAAIRHFAGKIPILGVCL
GHQSIGAAFGGKVVRSSTLMHGKTSPIHHNGQGLFRGLPNPFNATRYHSLVVERATFPDCLEITAWVEEGEVMGLAHREL
PIWGVQFHPESILTEGGMDILKNFLEMTQ

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=185, Percent_Identity=63.7837837837838, Blast_Score=264, Evalue=3e-72,
Organism=Escherichia coli, GI1787517, Length=191, Percent_Identity=43.455497382199, Blast_Score=147, Evalue=6e-37,
Organism=Escherichia coli, GI1786215, Length=175, Percent_Identity=26.2857142857143, Blast_Score=67, Evalue=6e-13,
Organism=Escherichia coli, GI1788854, Length=190, Percent_Identity=27.3684210526316, Blast_Score=64, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6322638, Length=188, Percent_Identity=47.3404255319149, Blast_Score=196, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6324361, Length=211, Percent_Identity=31.2796208530806, Blast_Score=94, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 20903; Mature: 20903

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLMIDNYDSFTYNIVQYFGELGEDVRVFRNDGITLEEIERLAPERLVISPGPCSPEEAG
CEEEEECCCCHHHHHHHHHHHHCHHHEEHHCCCCCHHHHHHCCCCEEEECCCCCCHHHHC
ISVAAIRHFAGKIPILGVCLGHQSIGAAFGGKVVRSSTLMHGKTSPIHHNGQGLFRGLPN
CHHHHHHHHHCCCCEEEEEECCHHHHHHHCCHHHHHHHHCCCCCCCCEECCCHHCCCCCC
PFNATRYHSLVVERATFPDCLEITAWVEEGEVMGLAHRELPIWGVQFHPESILTEGGMDI
CCCCHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEEECCCCCEEEEEECCHHHHHCCCHHH
LKNFLEMTQ
HHHHHHHCC
>Mature Secondary Structure
MLLMIDNYDSFTYNIVQYFGELGEDVRVFRNDGITLEEIERLAPERLVISPGPCSPEEAG
CEEEEECCCCHHHHHHHHHHHHCHHHEEHHCCCCCHHHHHHCCCCEEEECCCCCCHHHHC
ISVAAIRHFAGKIPILGVCLGHQSIGAAFGGKVVRSSTLMHGKTSPIHHNGQGLFRGLPN
CHHHHHHHHHCCCCEEEEEECCHHHHHHHCCHHHHHHHHCCCCCCCCEECCCHHCCCCCC
PFNATRYHSLVVERATFPDCLEITAWVEEGEVMGLAHRELPIWGVQFHPESILTEGGMDI
CCCCHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEEECCCCCEEEEEECCHHHHHCCCHHH
LKNFLEMTQ
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2404959; 659439 [H]