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The map label for this gene is pfpI [H]

Identifier: 78223612

GI number: 78223612

Start: 2724289

End: 2724792

Strand: Reverse

Name: pfpI [H]

Synonym: Gmet_2409

Alternate gene names: 78223612

Gene position: 2724792-2724289 (Counterclockwise)

Preceding gene: 78223613

Following gene: 78223611

Centisome position: 68.16

GC content: 63.49

Gene sequence:

>504_bases
ATGAAAGCACTCATCATCAGCGTCGACCAGTTTGAGGACTCCGAACTTCTCGCCCCCTACTACCGCCTGCTGGAGGAGGG
GATCCCGGTGGACATTGCATCAATCCACCGCGGAACCATCACGGGGAAGCACGGCTACGAGGTGCAGGCGGACAAGTCTC
TCGCGGAGGTGAATCCCGAGGGGTATGCCCTCCTTGTCCTTCCGGGCGGGAAGGCGCCGGCTGCCGTCCGAAAGGAACCC
GCCGCCCTGGAGATCTGCCGCAGCTTCTTTGCCCATAACAAGCCCGTTGCCGCCATCTGCCATGGCCCCCAGATCCTTAT
CAGTGCCGGTCTCCTGTCGGGACGGCGGGCCACCTGCTACCAGTCCGTGGCCGACGAAATGCGGGGGGCCGGTGCCCTCT
ACGAGGACAGCGAGGTGGTGGTGGATGGCAACCTGATCACCTCACGGCAGCCGTCGGACATCCCCGCCTTCATGCGCGAG
CTCATGAAGAAGCTCAAGGGATAG

Upstream 100 bases:

>100_bases
AGGCTGCCGAGGCGCGGCTGAAGTAACCAGGCACAATACGGGATGTAACGTAGGGGCAATTCGTGAATTGCCCCTACGCC
GTTTTCAGGGAGGAAAAGCC

Downstream 100 bases:

>100_bases
GATGTTCTGTTCGGGCCGACACTTTACAGGAAAGCCGGAAGGGAGTCCGTCCCGACCGGCTTTTTTGTGGCCTCTTCCCC
TCTTCACACCATGGGTTACT

Product: peptidase C56, PfpI

Products: NA

Alternate protein names: Intracellular protease I [H]

Number of amino acids: Translated: 167; Mature: 167

Protein sequence:

>167_residues
MKALIISVDQFEDSELLAPYYRLLEEGIPVDIASIHRGTITGKHGYEVQADKSLAEVNPEGYALLVLPGGKAPAAVRKEP
AALEICRSFFAHNKPVAAICHGPQILISAGLLSGRRATCYQSVADEMRGAGALYEDSEVVVDGNLITSRQPSDIPAFMRE
LMKKLKG

Sequences:

>Translated_167_residues
MKALIISVDQFEDSELLAPYYRLLEEGIPVDIASIHRGTITGKHGYEVQADKSLAEVNPEGYALLVLPGGKAPAAVRKEP
AALEICRSFFAHNKPVAAICHGPQILISAGLLSGRRATCYQSVADEMRGAGALYEDSEVVVDGNLITSRQPSDIPAFMRE
LMKKLKG
>Mature_167_residues
MKALIISVDQFEDSELLAPYYRLLEEGIPVDIASIHRGTITGKHGYEVQADKSLAEVNPEGYALLVLPGGKAPAAVRKEP
AALEICRSFFAHNKPVAAICHGPQILISAGLLSGRRATCYQSVADEMRGAGALYEDSEVVVDGNLITSRQPSDIPAFMRE
LMKKLKG

Specific function: Unknown

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PfpI endopeptidase domain [H]

Homologues:

Organism=Escherichia coli, GI87082219, Length=167, Percent_Identity=41.3173652694611, Blast_Score=123, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI17558714, Length=156, Percent_Identity=25.6410256410256, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI28571932, Length=167, Percent_Identity=30.5389221556886, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006286
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 18036; Mature: 18036

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALIISVDQFEDSELLAPYYRLLEEGIPVDIASIHRGTITGKHGYEVQADKSLAEVNPE
CCEEEEEECCCCCCCHHHHHHHHHHCCCCEEHHHHCCCCCCCCCCCEEECCCHHHHCCCC
GYALLVLPGGKAPAAVRKEPAALEICRSFFAHNKPVAAICHGPQILISAGLLSGRRATCY
CEEEEEECCCCCCHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCEEEECCCCCCCHHHHH
QSVADEMRGAGALYEDSEVVVDGNLITSRQPSDIPAFMRELMKKLKG
HHHHHHHHCCCCCCCCCEEEEECCEECCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKALIISVDQFEDSELLAPYYRLLEEGIPVDIASIHRGTITGKHGYEVQADKSLAEVNPE
CCEEEEEECCCCCCCHHHHHHHHHHCCCCEEHHHHCCCCCCCCCCCEEECCCHHHHCCCC
GYALLVLPGGKAPAAVRKEPAALEICRSFFAHNKPVAAICHGPQILISAGLLSGRRATCY
CEEEEEECCCCCCHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCEEEECCCCCCCHHHHH
QSVADEMRGAGALYEDSEVVVDGNLITSRQPSDIPAFMRELMKKLKG
HHHHHHHHCCCCCCCCCEEEEECCEECCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]