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The map label for this gene is etfA [H]

Identifier: 78223461

GI number: 78223461

Start: 2556130

End: 2557458

Strand: Reverse

Name: etfA [H]

Synonym: Gmet_2257

Alternate gene names: 78223461

Gene position: 2557458-2556130 (Counterclockwise)

Preceding gene: 78223462

Following gene: 78223459

Centisome position: 63.98

GC content: 64.03

Gene sequence:

>1329_bases
ATGACCGAAGCGAAGAGACCGATGAAGAAACCCCGTGGCGTGGCCCAGTTGATCGCCGGTGCCTGCATCGCCTGCGGCGC
CCGCTGCCAGAGCGTCTGTCCGGTCAACTGCGTCGACATGAACGATGCGGGGGAGCCGGTTGTCAACAGCGCCAAATGCA
TCGGCTGCCAGAAATGCGTCAAGATCTGCCCGGCCACCGCCCTGGAGATGTACTTCACCCCCGAAGAGCGGAAGATATTG
GACGAGCTGGCGGCACAGGGTGACCCCGTGGAAGAGGAGATCGATCCGGAAGCGGCCGCCCTGGCGGAGAAACTGGCTGC
CTACCGGGGGGTCTGGGTCTTCATCGAACAGACCGAGGGGGAGCCGGTCCGGGTCTCCTGGGAACTGCTCGGCGTCGGGA
AAGAACTGGCGGCCAAGCTGGGGGTGGAACTGTGCGCCATGGTCATCGGCGAGAACGTAGAGCACCTCTGCCGGGAGGCC
TTCGCCTACGGTGCCCGGAAAGCCTACCTGGTGGATGCGCCGGTCTTTAAACACTACCGCACCGAATCCTATGTGGAGGC
CTGCTGTCACCTCATCGCCAAGTACAAGCCGGAGGTGATCCTTATGGGGGCCACCGGCATGGGGCGGGACCTGGCGGGTG
CCGTCGCCACCCGGGTCTCCACCGGCCTTACCGCCGACTGCACCGGCCTGGATATCGACGGCAAAAGGAACCTCATGCAG
ACCCGCCCGGCGTTTGGCGGCAACATCATGGCCACCATCATGTGCGACAAGTTCCGGCCCCAGATGGCCACCGTCCGCCC
CAACGTCATGCCCATGCCGGAACACACCGGCAGCACCGCGGGGGAAATCGTCCGGGAAGAGTTCAGTGTCCCGGAAGCGA
ACATCTTCACCAAGGTCATCGAAATCATCCGGGACGCCAAGAGCAAGAGCCACGTGGACATAGCCGGGGCCGACTTCATC
GTCTCCGGCGGGCGGGGGGTGATGGCCCCCGAGAACTTCGCCATGCTACAGGAACTGGCCGACGAACTGTGCGGCGTGGT
GGGGGCATCAAGAAGTGCCGTCGATGCGGGATGGATGCCCCAGGAGCGGCAGGTGGGGCAGACGGGGAAAACGGTGCGTC
CCAAGATCTACATCGCCTGCGGGATCAGCGGTGCCATCCAGCACCTGGTGGGGATGCAGGACTCGGACGTCGTCATCGCC
ATCAACCGGGACCGCAACGCCCCCATCTTCGAGGTCGCCACCTACGGCATCGTCGGCGACCTGTTCCAGATCGTCCCCAT
GCTCACGGAACAGATCCGCGACCTGAAACTGCAGAAAAACAGGGACTAG

Upstream 100 bases:

>100_bases
TACGCCTCCGCGGCATTCCTTGGGCGCCTTGACCTTGCACGAAATCGACAGCCGGTAAACAATACATGTTTATTTTCTAT
CTGTTACCTGAGGTTTTCAA

Downstream 100 bases:

>100_bases
CAAAGAACAGGGACTAGGGGCTAGGTGTTGAGTGCCACGACATCGTGGACAACTTTTTGTGCCATGACATCGTGGACACT
CATCTGAATCACCGCAGTTT

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MTEAKRPMKKPRGVAQLIAGACIACGARCQSVCPVNCVDMNDAGEPVVNSAKCIGCQKCVKICPATALEMYFTPEERKIL
DELAAQGDPVEEEIDPEAAALAEKLAAYRGVWVFIEQTEGEPVRVSWELLGVGKELAAKLGVELCAMVIGENVEHLCREA
FAYGARKAYLVDAPVFKHYRTESYVEACCHLIAKYKPEVILMGATGMGRDLAGAVATRVSTGLTADCTGLDIDGKRNLMQ
TRPAFGGNIMATIMCDKFRPQMATVRPNVMPMPEHTGSTAGEIVREEFSVPEANIFTKVIEIIRDAKSKSHVDIAGADFI
VSGGRGVMAPENFAMLQELADELCGVVGASRSAVDAGWMPQERQVGQTGKTVRPKIYIACGISGAIQHLVGMQDSDVVIA
INRDRNAPIFEVATYGIVGDLFQIVPMLTEQIRDLKLQKNRD

Sequences:

>Translated_442_residues
MTEAKRPMKKPRGVAQLIAGACIACGARCQSVCPVNCVDMNDAGEPVVNSAKCIGCQKCVKICPATALEMYFTPEERKIL
DELAAQGDPVEEEIDPEAAALAEKLAAYRGVWVFIEQTEGEPVRVSWELLGVGKELAAKLGVELCAMVIGENVEHLCREA
FAYGARKAYLVDAPVFKHYRTESYVEACCHLIAKYKPEVILMGATGMGRDLAGAVATRVSTGLTADCTGLDIDGKRNLMQ
TRPAFGGNIMATIMCDKFRPQMATVRPNVMPMPEHTGSTAGEIVREEFSVPEANIFTKVIEIIRDAKSKSHVDIAGADFI
VSGGRGVMAPENFAMLQELADELCGVVGASRSAVDAGWMPQERQVGQTGKTVRPKIYIACGISGAIQHLVGMQDSDVVIA
INRDRNAPIFEVATYGIVGDLFQIVPMLTEQIRDLKLQKNRD
>Mature_441_residues
TEAKRPMKKPRGVAQLIAGACIACGARCQSVCPVNCVDMNDAGEPVVNSAKCIGCQKCVKICPATALEMYFTPEERKILD
ELAAQGDPVEEEIDPEAAALAEKLAAYRGVWVFIEQTEGEPVRVSWELLGVGKELAAKLGVELCAMVIGENVEHLCREAF
AYGARKAYLVDAPVFKHYRTESYVEACCHLIAKYKPEVILMGATGMGRDLAGAVATRVSTGLTADCTGLDIDGKRNLMQT
RPAFGGNIMATIMCDKFRPQMATVRPNVMPMPEHTGSTAGEIVREEFSVPEANIFTKVIEIIRDAKSKSHVDIAGADFIV
SGGRGVMAPENFAMLQELADELCGVVGASRSAVDAGWMPQERQVGQTGKTVRPKIYIACGISGAIQHLVGMQDSDVVIAI
NRDRNAPIFEVATYGIVGDLFQIVPMLTEQIRDLKLQKNRD

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=302, Percent_Identity=36.7549668874172, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI189181759, Length=281, Percent_Identity=37.3665480427046, Blast_Score=171, Evalue=1e-42,
Organism=Escherichia coli, GI1787990, Length=332, Percent_Identity=32.5301204819277, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1786226, Length=258, Percent_Identity=31.7829457364341, Blast_Score=119, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17506929, Length=296, Percent_Identity=36.8243243243243, Blast_Score=169, Evalue=3e-42,
Organism=Saccharomyces cerevisiae, GI6325261, Length=196, Percent_Identity=39.7959183673469, Blast_Score=147, Evalue=4e-36,
Organism=Drosophila melanogaster, GI17136898, Length=301, Percent_Identity=36.5448504983389, Blast_Score=174, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24652801, Length=301, Percent_Identity=36.5448504983389, Blast_Score=174, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 47829; Mature: 47698

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS00198 4FE4S_FERREDOXIN ; PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
7.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEAKRPMKKPRGVAQLIAGACIACGARCQSVCPVNCVDMNDAGEPVVNSAKCIGCQKCV
CCCCCCCHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCHHCCHHHHHHHHHH
KICPATALEMYFTPEERKILDELAAQGDPVEEEIDPEAAALAEKLAAYRGVWVFIEQTEG
HHCCCHHHHEEECCHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHCCEEEEEECCCC
EPVRVSWELLGVGKELAAKLGVELCAMVIGENVEHLCREAFAYGARKAYLVDAPVFKHYR
CCEEEEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEECCHHHHHHC
TESYVEACCHLIAKYKPEVILMGATGMGRDLAGAVATRVSTGLTADCTGLDIDGKRNLMQ
HHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHH
TRPAFGGNIMATIMCDKFRPQMATVRPNVMPMPEHTGSTAGEIVREEFSVPEANIFTKVI
CCCCCCCCEEEEEEECCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHH
EIIRDAKSKSHVDIAGADFIVSGGRGVMAPENFAMLQELADELCGVVGASRSAVDAGWMP
HHHHHCCCCCCEEEECCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
QERQVGQTGKTVRPKIYIACGISGAIQHLVGMQDSDVVIAINRDRNAPIFEVATYGIVGD
CHHHCCCCCCCCCCEEEEEECCHHHHHHHHCCCCCCEEEEEECCCCCCEEHHHHHHHHHH
LFQIVPMLTEQIRDLKLQKNRD
HHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TEAKRPMKKPRGVAQLIAGACIACGARCQSVCPVNCVDMNDAGEPVVNSAKCIGCQKCV
CCCCCCHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCHHCCHHHHHHHHHH
KICPATALEMYFTPEERKILDELAAQGDPVEEEIDPEAAALAEKLAAYRGVWVFIEQTEG
HHCCCHHHHEEECCHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHCCEEEEEECCCC
EPVRVSWELLGVGKELAAKLGVELCAMVIGENVEHLCREAFAYGARKAYLVDAPVFKHYR
CCEEEEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEECCHHHHHHC
TESYVEACCHLIAKYKPEVILMGATGMGRDLAGAVATRVSTGLTADCTGLDIDGKRNLMQ
HHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHH
TRPAFGGNIMATIMCDKFRPQMATVRPNVMPMPEHTGSTAGEIVREEFSVPEANIFTKVI
CCCCCCCCEEEEEEECCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHH
EIIRDAKSKSHVDIAGADFIVSGGRGVMAPENFAMLQELADELCGVVGASRSAVDAGWMP
HHHHHCCCCCCEEEECCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
QERQVGQTGKTVRPKIYIACGISGAIQHLVGMQDSDVVIAINRDRNAPIFEVATYGIVGD
CHHHCCCCCCCCCCEEEEEECCHHHHHHHHCCCCCCEEEEEECCCCCCEEHHHHHHHHHH
LFQIVPMLTEQIRDLKLQKNRD
HHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA