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The map label for this gene is bioD [H]

Identifier: 78222791

GI number: 78222791

Start: 1782811

End: 1783536

Strand: Reverse

Name: bioD [H]

Synonym: Gmet_1581

Alternate gene names: 78222791

Gene position: 1783536-1782811 (Counterclockwise)

Preceding gene: 78222792

Following gene: 78222790

Centisome position: 44.62

GC content: 59.09

Gene sequence:

>726_bases
GTGAGTAACGCAATCTTCATCACGGGGACTGACACCGGAGTCGGGAAAACGATAGTAACGGCGACTCTGGCGTGCCTTTT
GCGGAAACAAGGGATCAACGTGGGTGTCATGAAGCCGGTCACCAGCGGTTGCGTCGAGCAGAACGGCTCACTCGTCTCCG
AGGATGCGGAACTGCTTGCCTGGGCAGCAGGAGTACCTCTCGATGAAGAGTGCGCCCCCTATTGTCTCCGCACTCCCATT
GCTCCGTCAGTGGCCGCCTCCAGGGAGAACGTCCGGATCGATTTCTCGCGAATACGGAACGCATACGAGAGCCTTCTGGC
CCGCCATGACTTCGTGCTTGTGGAGGGAGCCGGAGGGCTTATGGTCCCCCTTTCGGGAGGGCTCATGGTGGCGGATCTGG
CGCTTGCACTGAAGCTTCCGCTTCTGGTGGTGGCACGCCCCAACCTCGGGACCATCAACCACACGGTGCTTACCTGCTTC
GCCGCGAAACAGCTCGGCATCGAGGTGCGGGGGACCATCATCAATTCTTACCCCGACAGACCCGACACAGCTGAAGAGTA
CGCACCACACCTTATTGACTCGTTGTCCGGCGCTCCCCTGCTCGGCGTATTCCCCAAGGTGGAAGCGGCCGACCAGCGGA
CCATTGTCGAAACCCTGACCAACCACCTGTCTGGCCAAGGCACCACAAAAATTCTATTGCGGGAGATTGGCATTGAATAC
ATCTGA

Upstream 100 bases:

>100_bases
AGCGGAACCATGATCGGCAACTACCTGACCACCACCGGCCGCCCCGCCGAGCAGGACTGGCAGATGCTCAGGGACCTGGA
ACTGGCTGTCGGAGGTTGTT

Downstream 100 bases:

>100_bases
CACCAAAACACTTCGTGAGTACGACCGCGCCCATGTCTGGCACCCCTTCACCCAGATGAAGGAGTGGGAGGAGAGTGACC
CTGTCGTCATTGTCAGGGGC

Product: dethiobiotin synthase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MSNAIFITGTDTGVGKTIVTATLACLLRKQGINVGVMKPVTSGCVEQNGSLVSEDAELLAWAAGVPLDEECAPYCLRTPI
APSVAASRENVRIDFSRIRNAYESLLARHDFVLVEGAGGLMVPLSGGLMVADLALALKLPLLVVARPNLGTINHTVLTCF
AAKQLGIEVRGTIINSYPDRPDTAEEYAPHLIDSLSGAPLLGVFPKVEAADQRTIVETLTNHLSGQGTTKILLREIGIEY
I

Sequences:

>Translated_241_residues
MSNAIFITGTDTGVGKTIVTATLACLLRKQGINVGVMKPVTSGCVEQNGSLVSEDAELLAWAAGVPLDEECAPYCLRTPI
APSVAASRENVRIDFSRIRNAYESLLARHDFVLVEGAGGLMVPLSGGLMVADLALALKLPLLVVARPNLGTINHTVLTCF
AAKQLGIEVRGTIINSYPDRPDTAEEYAPHLIDSLSGAPLLGVFPKVEAADQRTIVETLTNHLSGQGTTKILLREIGIEY
I
>Mature_240_residues
SNAIFITGTDTGVGKTIVTATLACLLRKQGINVGVMKPVTSGCVEQNGSLVSEDAELLAWAAGVPLDEECAPYCLRTPIA
PSVAASRENVRIDFSRIRNAYESLLARHDFVLVEGAGGLMVPLSGGLMVADLALALKLPLLVVARPNLGTINHTVLTCFA
AKQLGIEVRGTIINSYPDRPDTAEEYAPHLIDSLSGAPLLGVFPKVEAADQRTIVETLTNHLSGQGTTKILLREIGIEYI

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=206, Percent_Identity=33.0097087378641, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI87081944, Length=220, Percent_Identity=32.7272727272727, Blast_Score=87, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472
- InterPro:   IPR002586 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 25575; Mature: 25444

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNAIFITGTDTGVGKTIVTATLACLLRKQGINVGVMKPVTSGCVEQNGSLVSEDAELLA
CCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHCCCCEECCCHHHHH
WAAGVPLDEECAPYCLRTPIAPSVAASRENVRIDFSRIRNAYESLLARHDFVLVEGAGGL
HHCCCCCCCCCCCHHHCCCCCCHHHCCCCCEEEEHHHHHHHHHHHHHHCCEEEEECCCCE
MVPLSGGLMVADLALALKLPLLVVARPNLGTINHTVLTCFAAKQLGIEVRGTIINSYPDR
EEEECCCCHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHCCEEEEEEEEECCCCC
PDTAEEYAPHLIDSLSGAPLLGVFPKVEAADQRTIVETLTNHLSGQGTTKILLREIGIEY
CCCHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCC
I
C
>Mature Secondary Structure 
SNAIFITGTDTGVGKTIVTATLACLLRKQGINVGVMKPVTSGCVEQNGSLVSEDAELLA
CCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHCCCCEECCCHHHHH
WAAGVPLDEECAPYCLRTPIAPSVAASRENVRIDFSRIRNAYESLLARHDFVLVEGAGGL
HHCCCCCCCCCCCHHHCCCCCCHHHCCCCCEEEEHHHHHHHHHHHHHHCCEEEEECCCCE
MVPLSGGLMVADLALALKLPLLVVARPNLGTINHTVLTCFAAKQLGIEVRGTIINSYPDR
EEEECCCCHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHCCEEEEEEEEECCCCC
PDTAEEYAPHLIDSLSGAPLLGVFPKVEAADQRTIVETLTNHLSGQGTTKILLREIGIEY
CCCHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCC
I
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA