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The map label for this gene is yceE [C]

Identifier: 78222026

GI number: 78222026

Start: 885298

End: 886488

Strand: Direct

Name: yceE [C]

Synonym: Gmet_0806

Alternate gene names: 78222026

Gene position: 885298-886488 (Clockwise)

Preceding gene: 78222025

Following gene: 78222027

Centisome position: 22.15

GC content: 65.74

Gene sequence:

>1191_bases
ATGGAATCACGGGAACACCGGGCGGGAAAACTCCTGCTGCTCGCCTGCGTCATCAGCTTTGTCTGCTTCTTCGGCTCCTA
CATGAGGATACCGATCGTCCCCCTCTTTGCCACGTCGCTGGGGGCCGACACGGCGCAGGTGGGACTCATCAACAGCGCGT
TCATGCTGATGGCGGGAGCGCTCTCCATCCCCTCGGGACTCGTCTCGGATCGACTGGGGCGGCGGATACCGCTCCTGGGA
GGGCTGATCCTCCTGGCCGGCTCGTCGTTTCTCCTCTACTGGAGCAACACTCCCCTGCAAATGGGGGGGGTCTATCTCCT
CTTCGGCATCGGGCTGTCGGCCTTCTCGCCGACCCTCATGTCGTACGTGGCCGACGTTACCCCGCCGGAGGTCCTGGGCC
AGGCCTACGGCTGGTACACCATGGCTCTGTACGGCGGCATGACCCTCGGCCCCGCTGCCGGCGGTTTCCTCGGCACGGCG
CTGGGGCTTCGGCCGGTCTTTCTCGTGGCGGGGGGGCTGATCCTCGCCATGTTCGTCGTGGCGCTCATCTTTCTCCCCGC
GCCTTCCTCGGCCCAGCACCGCAGCGCAGTCCGTCCCGCCATCCTGCCGACCCTGGCAGGGCTCATGCACAACCGCCGGC
TCGTCGCCTGCCTCGTGGCAACCCTCGGCACCTGCTTCGGTTTCGGCATGTTCGTCACCTTCATGCCCCTCTATATCCGG
AGCCAGGGGATGCACTCGGGGCACGTGGGGTTTGTCTTCGCGGCCCAGGCCCTGGCTAACGCCATTTCACGCCTCCCCTC
GGGGAAACTGAGCGACCGGGTGGCTGACCGGAGTATCCTGGTAACTGGAGGGCTTGCCATTTTCGCCCTGGCGCTCGCCT
CCTTCGGCCTCTGCCGGTCCGTGGTCCCGCTCATGGGGGCCGCGGCGGTCATGGGGATAAGCATGGGGGTAGCCTTCACC
GCCGTCTGTGCGCTGATCGCCGATGTGGTGCCCCGGGAGCAGCGGGGGCTCGCCATGGGCTGCTACAATACCTGCGTTTA
TGTCGGGATGATGCTCTGCGCGGCCGGCATGGGGGCGTTCATCCGGGAGGAAGGCTTCAGGATCGGTTTTTTCCTGAATG
GCGTGGTCGGGGTGGCGACGTTACTGCTTTTCGTCACTCTCTACCGTCGGCCCGAGCCGGCAGCAGCATAA

Upstream 100 bases:

>100_bases
GCCATCGGGGTTACCACGGTGTTGGTCCGCTGCTGGGCAAGGCGCTTGCCGTGGGGAAAAAGCTATGAATTCGCCCAAGA
GGCTGAAGGGGTAGGTGCCC

Downstream 100 bases:

>100_bases
AGGAGGTCGAGATGGAGGAAGCACTACGTGCCGAGATCGGACGTTTTGTGGCGGAGAGCCCGGAAAACCGCTTCCCTGAT
GGCAGCGGACCCTACTTCGA

Product: major facilitator transporter

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MESREHRAGKLLLLACVISFVCFFGSYMRIPIVPLFATSLGADTAQVGLINSAFMLMAGALSIPSGLVSDRLGRRIPLLG
GLILLAGSSFLLYWSNTPLQMGGVYLLFGIGLSAFSPTLMSYVADVTPPEVLGQAYGWYTMALYGGMTLGPAAGGFLGTA
LGLRPVFLVAGGLILAMFVVALIFLPAPSSAQHRSAVRPAILPTLAGLMHNRRLVACLVATLGTCFGFGMFVTFMPLYIR
SQGMHSGHVGFVFAAQALANAISRLPSGKLSDRVADRSILVTGGLAIFALALASFGLCRSVVPLMGAAAVMGISMGVAFT
AVCALIADVVPREQRGLAMGCYNTCVYVGMMLCAAGMGAFIREEGFRIGFFLNGVVGVATLLLFVTLYRRPEPAAA

Sequences:

>Translated_396_residues
MESREHRAGKLLLLACVISFVCFFGSYMRIPIVPLFATSLGADTAQVGLINSAFMLMAGALSIPSGLVSDRLGRRIPLLG
GLILLAGSSFLLYWSNTPLQMGGVYLLFGIGLSAFSPTLMSYVADVTPPEVLGQAYGWYTMALYGGMTLGPAAGGFLGTA
LGLRPVFLVAGGLILAMFVVALIFLPAPSSAQHRSAVRPAILPTLAGLMHNRRLVACLVATLGTCFGFGMFVTFMPLYIR
SQGMHSGHVGFVFAAQALANAISRLPSGKLSDRVADRSILVTGGLAIFALALASFGLCRSVVPLMGAAAVMGISMGVAFT
AVCALIADVVPREQRGLAMGCYNTCVYVGMMLCAAGMGAFIREEGFRIGFFLNGVVGVATLLLFVTLYRRPEPAAA
>Mature_396_residues
MESREHRAGKLLLLACVISFVCFFGSYMRIPIVPLFATSLGADTAQVGLINSAFMLMAGALSIPSGLVSDRLGRRIPLLG
GLILLAGSSFLLYWSNTPLQMGGVYLLFGIGLSAFSPTLMSYVADVTPPEVLGQAYGWYTMALYGGMTLGPAAGGFLGTA
LGLRPVFLVAGGLILAMFVVALIFLPAPSSAQHRSAVRPAILPTLAGLMHNRRLVACLVATLGTCFGFGMFVTFMPLYIR
SQGMHSGHVGFVFAAQALANAISRLPSGKLSDRVADRSILVTGGLAIFALALASFGLCRSVVPLMGAAAVMGISMGVAFT
AVCALIADVVPREQRGLAMGCYNTCVYVGMMLCAAGMGAFIREEGFRIGFFLNGVVGVATLLLFVTLYRRPEPAAA

Specific function: Unknown

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001958 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 41491; Mature: 41491

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESREHRAGKLLLLACVISFVCFFGSYMRIPIVPLFATSLGADTAQVGLINSAFMLMAGA
CCCCHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
LSIPSGLVSDRLGRRIPLLGGLILLAGSSFLLYWSNTPLQMGGVYLLFGIGLSAFSPTLM
HHCCCHHHHHHHCCCCHHHHHHHHHHCCCEEEEECCCCCHHCCHHHHHHHCHHHHHHHHH
SYVADVTPPEVLGQAYGWYTMALYGGMTLGPAAGGFLGTALGLRPVFLVAGGLILAMFVV
HHHHHCCCHHHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ALIFLPAPSSAQHRSAVRPAILPTLAGLMHNRRLVACLVATLGTCFGFGMFVTFMPLYIR
HHHHCCCCCCHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SQGMHSGHVGFVFAAQALANAISRLPSGKLSDRVADRSILVTGGLAIFALALASFGLCRS
HCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHCCCEEEEECCHHHHHHHHHHHHHHHH
VVPLMGAAAVMGISMGVAFTAVCALIADVVPREQRGLAMGCYNTCVYVGMMLCAAGMGAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHCCHHH
IREEGFRIGFFLNGVVGVATLLLFVTLYRRPEPAAA
HHHCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MESREHRAGKLLLLACVISFVCFFGSYMRIPIVPLFATSLGADTAQVGLINSAFMLMAGA
CCCCHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
LSIPSGLVSDRLGRRIPLLGGLILLAGSSFLLYWSNTPLQMGGVYLLFGIGLSAFSPTLM
HHCCCHHHHHHHCCCCHHHHHHHHHHCCCEEEEECCCCCHHCCHHHHHHHCHHHHHHHHH
SYVADVTPPEVLGQAYGWYTMALYGGMTLGPAAGGFLGTALGLRPVFLVAGGLILAMFVV
HHHHHCCCHHHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ALIFLPAPSSAQHRSAVRPAILPTLAGLMHNRRLVACLVATLGTCFGFGMFVTFMPLYIR
HHHHCCCCCCHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SQGMHSGHVGFVFAAQALANAISRLPSGKLSDRVADRSILVTGGLAIFALALASFGLCRS
HCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHCCCEEEEECCHHHHHHHHHHHHHHHH
VVPLMGAAAVMGISMGVAFTAVCALIADVVPREQRGLAMGCYNTCVYVGMMLCAAGMGAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHCCHHH
IREEGFRIGFFLNGVVGVATLLLFVTLYRRPEPAAA
HHHCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]