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The map label for this gene is sucD [H]

Identifier: 78221950

GI number: 78221950

Start: 802382

End: 803257

Strand: Direct

Name: sucD [H]

Synonym: Gmet_0730

Alternate gene names: 78221950

Gene position: 802382-803257 (Clockwise)

Preceding gene: 78221949

Following gene: 78221951

Centisome position: 20.07

GC content: 65.75

Gene sequence:

>876_bases
ATGTCCATACTCATCAACAAGGATTCAAAGATAGTCGTCCAGGGAATCACGGGCCGCAGCGGCCTCTTCCACACCCAGCA
GTGCCGGGACTATGGCTCCAGGATCGTGGCCGGCGTCACCCCGGGCAAGGGGGGGATCCACATCGAGGGGATTCCGGTCT
TCAATACGGTGGAGGAGGCGGTGCGGTACACCGGCGCCAATGTCTCCATGATTTTCGTTCCACCCCCTGGGGCCGCCGAC
GCCATCCTTGAGGCGGCCGACGCGGGGGTCGACCTGGCGGTCTGCATCACCGAAGGGATCCCGGTGCGCGACATGGTGCC
GGTGAAGCGGATTCTCCAGGGGAGCAAGACCCGCCTCGTGGGGCCCAACTGCCCCGGCGTCATCACCCCGGGCGAGTGCA
AGGTGGGGATCATGCCCGGCTACATCCACAAGCCCGGCAAGATCGGCGTCGTCTCCCGCAGCGGCACCCTCACCTACGAG
GCGGTGAAGCAGATCACCGAGGCGGGGCTCGGCCAGTCCACCTGTGTCGGCATCGGCGGCGACCCCATCATCGGCATGCA
GTTCATCGATGTCCTGAAGCTTTTCAACGAGGACAAGCAAACCGAGGCGGTCTTCATGATCGGCGAGATCGGCGGGAGCG
CCGAAGAGGACGCCGCCGAGTGGATCCGGGAGAACATGAAGAAGCCCGTGGCCGCCTTCATCGCCGGGGTCACCGCCCCC
CCGGGAAAGCGGATGGGCCATGCCGGCGCCATCATCACCGGCGGGAAGGGAAAGGCGGAGGACAAGATTCGCACCCTGGG
CGAGTGCGGCGTGGTCGTGGCCCCGAGCCCCACGAAAATGGGGGCGGCCATGCTGGAGGCCCTTGGCAAGAAGTAA

Upstream 100 bases:

>100_bases
TCAACGTCCAGACCGCCGACTCCCTCGGTGAGGGGGCGGAGCGGATCGTGCAGATGCTGGGCTGACGGCCATTACATTAC
AGACAACACGGAGATCATCA

Downstream 100 bases:

>100_bases
GGAGTTCCGTTCCGTTATTGATTGGGAAGGGCTATGGCCAGGAAGGCATGGCCCTTCTTTTTTGCCGGGATTTTGTGTAT
CCTCCCTGGAGGCAAACACT

Product: succinyl-CoA synthetase (ADP-forming) subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MSILINKDSKIVVQGITGRSGLFHTQQCRDYGSRIVAGVTPGKGGIHIEGIPVFNTVEEAVRYTGANVSMIFVPPPGAAD
AILEAADAGVDLAVCITEGIPVRDMVPVKRILQGSKTRLVGPNCPGVITPGECKVGIMPGYIHKPGKIGVVSRSGTLTYE
AVKQITEAGLGQSTCVGIGGDPIIGMQFIDVLKLFNEDKQTEAVFMIGEIGGSAEEDAAEWIRENMKKPVAAFIAGVTAP
PGKRMGHAGAIITGGKGKAEDKIRTLGECGVVVAPSPTKMGAAMLEALGKK

Sequences:

>Translated_291_residues
MSILINKDSKIVVQGITGRSGLFHTQQCRDYGSRIVAGVTPGKGGIHIEGIPVFNTVEEAVRYTGANVSMIFVPPPGAAD
AILEAADAGVDLAVCITEGIPVRDMVPVKRILQGSKTRLVGPNCPGVITPGECKVGIMPGYIHKPGKIGVVSRSGTLTYE
AVKQITEAGLGQSTCVGIGGDPIIGMQFIDVLKLFNEDKQTEAVFMIGEIGGSAEEDAAEWIRENMKKPVAAFIAGVTAP
PGKRMGHAGAIITGGKGKAEDKIRTLGECGVVVAPSPTKMGAAMLEALGKK
>Mature_290_residues
SILINKDSKIVVQGITGRSGLFHTQQCRDYGSRIVAGVTPGKGGIHIEGIPVFNTVEEAVRYTGANVSMIFVPPPGAADA
ILEAADAGVDLAVCITEGIPVRDMVPVKRILQGSKTRLVGPNCPGVITPGECKVGIMPGYIHKPGKIGVVSRSGTLTYEA
VKQITEAGLGQSTCVGIGGDPIIGMQFIDVLKLFNEDKQTEAVFMIGEIGGSAEEDAAEWIRENMKKPVAAFIAGVTAPP
GKRMGHAGAIITGGKGKAEDKIRTLGECGVVVAPSPTKMGAAMLEALGKK

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=294, Percent_Identity=59.5238095238095, Blast_Score=302, Evalue=3e-82,
Organism=Homo sapiens, GI38569423, Length=309, Percent_Identity=29.126213592233, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI38569421, Length=309, Percent_Identity=29.126213592233, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI1786949, Length=288, Percent_Identity=62.1527777777778, Blast_Score=360, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI17550194, Length=295, Percent_Identity=58.9830508474576, Blast_Score=328, Evalue=3e-90,
Organism=Caenorhabditis elegans, GI17553126, Length=292, Percent_Identity=58.5616438356164, Blast_Score=323, Evalue=6e-89,
Organism=Caenorhabditis elegans, GI17557344, Length=303, Percent_Identity=25.4125412541254, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17551266, Length=303, Percent_Identity=24.4224422442244, Blast_Score=76, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6324716, Length=298, Percent_Identity=50.3355704697987, Blast_Score=280, Evalue=2e-76,
Organism=Drosophila melanogaster, GI21356559, Length=292, Percent_Identity=53.0821917808219, Blast_Score=312, Evalue=1e-85,
Organism=Drosophila melanogaster, GI28574296, Length=294, Percent_Identity=56.8027210884354, Blast_Score=307, Evalue=4e-84,
Organism=Drosophila melanogaster, GI281363477, Length=314, Percent_Identity=26.4331210191083, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI281363475, Length=314, Percent_Identity=26.4331210191083, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI281363473, Length=314, Percent_Identity=26.4331210191083, Blast_Score=85, Evalue=6e-17,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 30217; Mature: 30085

Theoretical pI: Translated: 8.12; Mature: 8.12

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILINKDSKIVVQGITGRSGLFHTQQCRDYGSRIVAGVTPGKGGIHIEGIPVFNTVEEA
CEEEEECCCEEEEEECCCCCCCCCHHHHHHHCCEEEEEECCCCCCEEEECCCHHHHHHHH
VRYTGANVSMIFVPPPGAADAILEAADAGVDLAVCITEGIPVRDMVPVKRILQGSKTRLV
HHHCCCCEEEEEECCCCHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCEEE
GPNCPGVITPGECKVGIMPGYIHKPGKIGVVSRSGTLTYEAVKQITEAGLGQSTCVGIGG
CCCCCCEECCCCEEEEECCCCEECCCCEEEEECCCCCHHHHHHHHHHHCCCCCEEEECCC
DPIIGMQFIDVLKLFNEDKQTEAVFMIGEIGGSAEEDAAEWIRENMKKPVAAFIAGVTAP
CCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCHHHHHHHCCCCC
PGKRMGHAGAIITGGKGKAEDKIRTLGECGVVVAPSPTKMGAAMLEALGKK
CCCCCCCCCEEEECCCCCCHHHHHHHHCCCEEECCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SILINKDSKIVVQGITGRSGLFHTQQCRDYGSRIVAGVTPGKGGIHIEGIPVFNTVEEA
EEEEECCCEEEEEECCCCCCCCCHHHHHHHCCEEEEEECCCCCCEEEECCCHHHHHHHH
VRYTGANVSMIFVPPPGAADAILEAADAGVDLAVCITEGIPVRDMVPVKRILQGSKTRLV
HHHCCCCEEEEEECCCCHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCEEE
GPNCPGVITPGECKVGIMPGYIHKPGKIGVVSRSGTLTYEAVKQITEAGLGQSTCVGIGG
CCCCCCEECCCCEEEEECCCCEECCCCEEEEECCCCCHHHHHHHHHHHCCCCCEEEECCC
DPIIGMQFIDVLKLFNEDKQTEAVFMIGEIGGSAEEDAAEWIRENMKKPVAAFIAGVTAP
CCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCHHHHHHHCCCCC
PGKRMGHAGAIITGGKGKAEDKIRTLGECGVVVAPSPTKMGAAMLEALGKK
CCCCCCCCCEEEECCCCCCHHHHHHHHCCCEEECCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA