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The map label for this gene is sucC

Identifier: 78221949

GI number: 78221949

Start: 801189

End: 802346

Strand: Direct

Name: sucC

Synonym: Gmet_0729

Alternate gene names: 78221949

Gene position: 801189-802346 (Clockwise)

Preceding gene: 78221945

Following gene: 78221950

Centisome position: 20.04

GC content: 64.51

Gene sequence:

>1158_bases
ATGAACATTCATGAGTACCAGGCAAAGGAGATCCTGAGCTCGTACAGCATCCCGGTCCCGCGGGGGCGGGTGGCACTCAC
GTCCGACCAGGTGGAGCGGGCTGCCAAGGAGATGGGGGGGCGCTGCGTCATCAAGGCCCAGATCTACGCCGGTGGCCGCG
GCAAGGCCGGCGGGGTGAAGCTGGTCCATCACCCGGAGCAGGCTCAGGATTACGGCAAGGAGCTCTTTGGCAAGCGTCTC
GTGACTCCCCAGACCGGCCCCGAGGGGCTGAAGGTCCGCCGCATCCTCGTGGAGGAGGCGGTGGAGATCGCCCGGGAGTT
CTACCTCTCCATCACTCTGGACCGGGCAACCTCCCGTTATTGCCTCATCGCCTCCGCCGAAGGGGGGGTAGACATTGAGG
AAGTGGCCCAGAAGTCCCCCGAGAAGATCCACGTCCTCACCATCGACCCCTACACGGGCCTTCGCCCCTACCTGGCCCGC
AAGATCGCCCTGGCCCTGGGGCTCACGGGGAGCCTCTGCGAGGACTGCGTGGAGCTGATGCTGAACCTCTACAAGGTCGT
GCTCGACAAGGACTGCTCCCTGGTGGAGATCAACCCCCTGGTGGTGACCCGGGCCGGCTGGCTCATGGCCATGGACGCCA
AGATCAACTTCGACGACAACGCCGTCTTCCGGCACCGGGAATACCCCGACATGATGGATTACTCCCAGCTGGACACCCTG
GAGATCAATGCCGGCAAGTACGATCTCTCCTACATCAAGCTCTCCGGCAACATCGGCTGCATGGTGAACGGCGCCGGCCT
GGCCATGGCCACCCTCGACGTGCTGAAGGAATACGGCGGCGAGCCGGCCAACTTCCTGGACGTGGGGGGCGGCGCCACCC
GCGAGAAGGTGGCCGAGGCCTTCAAGATCATCCTGGAGGATGCGGACGTGAAGGGGGTCTTTGTCAACATCTTCGGCGGG
ATCATGCGCTGCGACGTCATCGCCCAAGGGATCATCGAGGCGGCAAGCGAGGTCCACTGCACCCTTCCCATCGTGGTCCG
GATGGACGGGAGCAAGGTGCTGGAGGGGAAGCAACTCTTGGTGGATTCGGGGCTCAACGTCCAGACCGCCGACTCCCTCG
GTGAGGGGGCGGAGCGGATCGTGCAGATGCTGGGCTGA

Upstream 100 bases:

>100_bases
TGGTTATACGGAGAAGCGGTATATTGAATTTTATTCTTAACCACTGTTTTATTTTGTGGTATACCTAAAATACTTTTATT
TAAACTAAAAAGGAGGGGGC

Downstream 100 bases:

>100_bases
CGGCCATTACATTACAGACAACACGGAGATCATCAATGTCCATACTCATCAACAAGGATTCAAAGATAGTCGTCCAGGGA
ATCACGGGCCGCAGCGGCCT

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MNIHEYQAKEILSSYSIPVPRGRVALTSDQVERAAKEMGGRCVIKAQIYAGGRGKAGGVKLVHHPEQAQDYGKELFGKRL
VTPQTGPEGLKVRRILVEEAVEIAREFYLSITLDRATSRYCLIASAEGGVDIEEVAQKSPEKIHVLTIDPYTGLRPYLAR
KIALALGLTGSLCEDCVELMLNLYKVVLDKDCSLVEINPLVVTRAGWLMAMDAKINFDDNAVFRHREYPDMMDYSQLDTL
EINAGKYDLSYIKLSGNIGCMVNGAGLAMATLDVLKEYGGEPANFLDVGGGATREKVAEAFKIILEDADVKGVFVNIFGG
IMRCDVIAQGIIEAASEVHCTLPIVVRMDGSKVLEGKQLLVDSGLNVQTADSLGEGAERIVQMLG

Sequences:

>Translated_385_residues
MNIHEYQAKEILSSYSIPVPRGRVALTSDQVERAAKEMGGRCVIKAQIYAGGRGKAGGVKLVHHPEQAQDYGKELFGKRL
VTPQTGPEGLKVRRILVEEAVEIAREFYLSITLDRATSRYCLIASAEGGVDIEEVAQKSPEKIHVLTIDPYTGLRPYLAR
KIALALGLTGSLCEDCVELMLNLYKVVLDKDCSLVEINPLVVTRAGWLMAMDAKINFDDNAVFRHREYPDMMDYSQLDTL
EINAGKYDLSYIKLSGNIGCMVNGAGLAMATLDVLKEYGGEPANFLDVGGGATREKVAEAFKIILEDADVKGVFVNIFGG
IMRCDVIAQGIIEAASEVHCTLPIVVRMDGSKVLEGKQLLVDSGLNVQTADSLGEGAERIVQMLG
>Mature_385_residues
MNIHEYQAKEILSSYSIPVPRGRVALTSDQVERAAKEMGGRCVIKAQIYAGGRGKAGGVKLVHHPEQAQDYGKELFGKRL
VTPQTGPEGLKVRRILVEEAVEIAREFYLSITLDRATSRYCLIASAEGGVDIEEVAQKSPEKIHVLTIDPYTGLRPYLAR
KIALALGLTGSLCEDCVELMLNLYKVVLDKDCSLVEINPLVVTRAGWLMAMDAKINFDDNAVFRHREYPDMMDYSQLDTL
EINAGKYDLSYIKLSGNIGCMVNGAGLAMATLDVLKEYGGEPANFLDVGGGATREKVAEAFKIILEDADVKGVFVNIFGG
IMRCDVIAQGIIEAASEVHCTLPIVVRMDGSKVLEGKQLLVDSGLNVQTADSLGEGAERIVQMLG

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=391, Percent_Identity=45.2685421994885, Blast_Score=346, Evalue=3e-95,
Organism=Homo sapiens, GI157779135, Length=381, Percent_Identity=43.8320209973753, Blast_Score=314, Evalue=8e-86,
Organism=Homo sapiens, GI294862256, Length=359, Percent_Identity=44.2896935933148, Blast_Score=300, Evalue=1e-81,
Organism=Escherichia coli, GI1786948, Length=382, Percent_Identity=50.261780104712, Blast_Score=380, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI17567829, Length=390, Percent_Identity=46.1538461538462, Blast_Score=328, Evalue=2e-90,
Organism=Caenorhabditis elegans, GI17539378, Length=394, Percent_Identity=41.6243654822335, Blast_Score=303, Evalue=9e-83,
Organism=Saccharomyces cerevisiae, GI6321683, Length=394, Percent_Identity=43.1472081218274, Blast_Score=341, Evalue=1e-94,
Organism=Drosophila melanogaster, GI161078106, Length=391, Percent_Identity=46.2915601023018, Blast_Score=336, Evalue=1e-92,
Organism=Drosophila melanogaster, GI24645208, Length=391, Percent_Identity=46.2915601023018, Blast_Score=336, Evalue=1e-92,
Organism=Drosophila melanogaster, GI281361397, Length=392, Percent_Identity=46.4285714285714, Blast_Score=335, Evalue=4e-92,
Organism=Drosophila melanogaster, GI281361395, Length=392, Percent_Identity=46.4285714285714, Blast_Score=335, Evalue=4e-92,
Organism=Drosophila melanogaster, GI21356231, Length=396, Percent_Identity=40.4040404040404, Blast_Score=300, Evalue=8e-82,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 41914; Mature: 41914

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHEYQAKEILSSYSIPVPRGRVALTSDQVERAAKEMGGRCVIKAQIYAGGRGKAGGVK
CCCHHHHHHHHHHHCCCCCCCCCEEECHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCEE
LVHHPEQAQDYGKELFGKRLVTPQTGPEGLKVRRILVEEAVEIAREFYLSITLDRATSRY
EEECCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEECCCCCE
CLIASAEGGVDIEEVAQKSPEKIHVLTIDPYTGLRPYLARKIALALGLTGSLCEDCVELM
EEEEECCCCCCHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
LNLYKVVLDKDCSLVEINPLVVTRAGWLMAMDAKINFDDNAVFRHREYPDMMDYSQLDTL
HHHHHHHHCCCCCEEEECCEEEEECCEEEEEEEEECCCCCCEEECCCCCCCCCCCCCCEE
EINAGKYDLSYIKLSGNIGCMVNGAGLAMATLDVLKEYGGEPANFLDVGGGATREKVAEA
EECCCEEEEEEEEEECCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHH
FKIILEDADVKGVFVNIFGGIMRCDVIAQGIIEAASEVHCTLPIVVRMDGSKVLEGKQLL
HHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEECCCCCCCCCEEE
VDSGLNVQTADSLGEGAERIVQMLG
EECCCCEEEHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MNIHEYQAKEILSSYSIPVPRGRVALTSDQVERAAKEMGGRCVIKAQIYAGGRGKAGGVK
CCCHHHHHHHHHHHCCCCCCCCCEEECHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCEE
LVHHPEQAQDYGKELFGKRLVTPQTGPEGLKVRRILVEEAVEIAREFYLSITLDRATSRY
EEECCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEECCCCCE
CLIASAEGGVDIEEVAQKSPEKIHVLTIDPYTGLRPYLARKIALALGLTGSLCEDCVELM
EEEEECCCCCCHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
LNLYKVVLDKDCSLVEINPLVVTRAGWLMAMDAKINFDDNAVFRHREYPDMMDYSQLDTL
HHHHHHHHCCCCCEEEECCEEEEECCEEEEEEEEECCCCCCEEECCCCCCCCCCCCCCEE
EINAGKYDLSYIKLSGNIGCMVNGAGLAMATLDVLKEYGGEPANFLDVGGGATREKVAEA
EECCCEEEEEEEEEECCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHH
FKIILEDADVKGVFVNIFGGIMRCDVIAQGIIEAASEVHCTLPIVVRMDGSKVLEGKQLL
HHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEECCCCCCCCCEEE
VDSGLNVQTADSLGEGAERIVQMLG
EECCCCEEEHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA