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The map label for this gene is arnC [H]

Identifier: 78221810

GI number: 78221810

Start: 655692

End: 656372

Strand: Direct

Name: arnC [H]

Synonym: Gmet_0589

Alternate gene names: 78221810

Gene position: 655692-656372 (Clockwise)

Preceding gene: 78221809

Following gene: 78221811

Centisome position: 16.4

GC content: 56.68

Gene sequence:

>681_bases
ATGAAACTGTCGGTGGTGATGCCGGTTTACAACGAGAAGGCAACCCTTCGTGCCATCTATGAACAGGTGGCGGCGGTGAC
GATCGACAAGGAGATAATTCTTGTGGATGACTGCTCCACCGACGGCACCCGGGAGATCGTCAGGGAACTGGGTGCCACTG
GGGCCACGGTGGTTCTCCATGACCGGAACATGGGGAAGGGGGCTGCCTTGAGGAGCGGCTTCCGGCATGTTACGGGGGAC
GTGGTTCTCATTCAGGATGCCGATCTTGAGTACGATCCGGGACAGTACCCGCTGCTGATCCAGCCGATTCTGAACGGCGA
GGTCGATGTGGTCTATGGCTCCCGGTTCCTCTCCGGGGAACGCAGCCTCGGCATGTCGTTCTGGAACAGGGCCGGGAACA
GGATACTGACATATCTTTCCAACACGCTGACAAAACTGGAGCTGACCGACGTCGAAACCTGTTACAAGGTCTTCAGCAGG
GACGTCCTGGAGCGGATCACCATAGAAGAGAACCGGTTCGGCTGTGAACCGGAGATCACCGCAAAGCTGGCGAAACTGGG
GGTGAGAATACGTGAGGTCGGGATATCATATCGCGGCAGAACATCCGCCGAGGGGAAGAAAATCGGCTGGAGGGATTTCA
TTTCGTCGGTGAGATGCATAGCCAAGTATACTTTGACGTGA

Upstream 100 bases:

>100_bases
GCGGAACAATGCTGGAAGATAGGATGCTTGTGACGATGATACGTGGTGCCGGATGGCGATGCGATGAGCCCTGTTATTTA
TCCTTGGCGGATTTCGAATC

Downstream 100 bases:

>100_bases
TGGGTTGATAACGTCACGGAAGCGTACTGCCGTTTCACGCTAAAGATCGGGGGTGAGTTGCTTGAAGAACAAAATGATCG
GCTTTTTCCTGATGGTGTTT

Product: glycosyl transferase family protein

Products: NA

Alternate protein names: Undecaprenyl-phosphate Ara4FN transferase; Ara4FN transferase [H]

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MKLSVVMPVYNEKATLRAIYEQVAAVTIDKEIILVDDCSTDGTREIVRELGATGATVVLHDRNMGKGAALRSGFRHVTGD
VVLIQDADLEYDPGQYPLLIQPILNGEVDVVYGSRFLSGERSLGMSFWNRAGNRILTYLSNTLTKLELTDVETCYKVFSR
DVLERITIEENRFGCEPEITAKLAKLGVRIREVGISYRGRTSAEGKKIGWRDFISSVRCIAKYTLT

Sequences:

>Translated_226_residues
MKLSVVMPVYNEKATLRAIYEQVAAVTIDKEIILVDDCSTDGTREIVRELGATGATVVLHDRNMGKGAALRSGFRHVTGD
VVLIQDADLEYDPGQYPLLIQPILNGEVDVVYGSRFLSGERSLGMSFWNRAGNRILTYLSNTLTKLELTDVETCYKVFSR
DVLERITIEENRFGCEPEITAKLAKLGVRIREVGISYRGRTSAEGKKIGWRDFISSVRCIAKYTLT
>Mature_226_residues
MKLSVVMPVYNEKATLRAIYEQVAAVTIDKEIILVDDCSTDGTREIVRELGATGATVVLHDRNMGKGAALRSGFRHVTGD
VVLIQDADLEYDPGQYPLLIQPILNGEVDVVYGSRFLSGERSLGMSFWNRAGNRILTYLSNTLTKLELTDVETCYKVFSR
DVLERITIEENRFGCEPEITAKLAKLGVRIREVGISYRGRTSAEGKKIGWRDFISSVRCIAKYTLT

Specific function: Catalyzes the transfer of 4-deoxy-4-formamido-L- arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides [H]

COG id: COG0463

COG function: function code M; Glycosyltransferases involved in cell wall biogenesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family [H]

Homologues:

Organism=Homo sapiens, GI4503363, Length=230, Percent_Identity=27.8260869565217, Blast_Score=93, Evalue=2e-19,
Organism=Escherichia coli, GI1788588, Length=212, Percent_Identity=27.8301886792453, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788692, Length=179, Percent_Identity=30.7262569832402, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71999402, Length=213, Percent_Identity=27.2300469483568, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24585265, Length=215, Percent_Identity=29.3023255813954, Blast_Score=94, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022857
- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: =2.7.8.30 [H]

Molecular weight: Translated: 25244; Mature: 25244

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLSVVMPVYNEKATLRAIYEQVAAVTIDKEIILVDDCSTDGTREIVRELGATGATVVLH
CCEEEEECCCCCHHHHHHHHHHHHHEEECCEEEEEECCCCCCHHHHHHHHCCCCCEEEEE
DRNMGKGAALRSGFRHVTGDVVLIQDADLEYDPGQYPLLIQPILNGEVDVVYGSRFLSGE
CCCCCCCHHHHHCCHHCCCCEEEEECCCCCCCCCCCCEEEEECCCCCEEEEECCEEECCC
RSLGMSFWNRAGNRILTYLSNTLTKLELTDVETCYKVFSRDVLERITIEENRFGCEPEIT
HHHHHHHHHHCCHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
AKLAKLGVRIREVGISYRGRTSAEGKKIGWRDFISSVRCIAKYTLT
HHHHHHCHHHEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKLSVVMPVYNEKATLRAIYEQVAAVTIDKEIILVDDCSTDGTREIVRELGATGATVVLH
CCEEEEECCCCCHHHHHHHHHHHHHEEECCEEEEEECCCCCCHHHHHHHHCCCCCEEEEE
DRNMGKGAALRSGFRHVTGDVVLIQDADLEYDPGQYPLLIQPILNGEVDVVYGSRFLSGE
CCCCCCCHHHHHCCHHCCCCEEEEECCCCCCCCCCCCEEEEECCCCCEEEEECCEEECCC
RSLGMSFWNRAGNRILTYLSNTLTKLELTDVETCYKVFSRDVLERITIEENRFGCEPEIT
HHHHHHHHHHCCHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
AKLAKLGVRIREVGISYRGRTSAEGKKIGWRDFISSVRCIAKYTLT
HHHHHHCHHHEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA