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The map label for this gene is nuoA1

Identifier: 78221377

GI number: 78221377

Start: 182924

End: 183340

Strand: Direct

Name: nuoA1

Synonym: Gmet_0152

Alternate gene names: 78221377

Gene position: 182924-183340 (Clockwise)

Preceding gene: 78221376

Following gene: 78221378

Centisome position: 4.58

GC content: 64.27

Gene sequence:

>417_bases
ATGCAGCAAACCACCGTCGCAAACCATTCCCTCTTCCCGACCCTGCCGCCCGAGTTCCTCCCCCTGGCGCTCTATACCGT
TGCGGCAACCGTCCTGATCGGCGTCCTCCTCCTGGCCGCCTGGTGGCTCGGCGCGAAGACCACCAACCGCAACAAGGAAC
TCCCCTACGAATCCGGGGTCATCCCCACGGGAAGCGCCCGCCTCGCCTATCCGGTCCCCTTCTACCTCATCGCCATCTTC
TTCATCGTCTTCGACGTGGAGGCGGCCTTCATCTTCGCCTGGGCCACGGCCTGGCGCGAACTGGGTCTGGCGGGGCTCAT
CCATATCACCTTCTTCATCGTCATCCTCCTCCTGGGGCTCGTCTGGCTCTGGATGAAGGGAGGCCTCGACTGGGGCCCTT
CCCGTGAACGGAGGTGA

Upstream 100 bases:

>100_bases
ACCGGGCTGAATCGGCAGCCGTCCATTACGACCGTTGACATGAGTTCCTCGTGCGCTAGAGTTTGAACTTGGCATTTCAC
TCGACATCACGGAGAGTAGA

Downstream 100 bases:

>100_bases
GAAACGTGGCTTTTCCGCAATCTCTGCGTAAGTCTTCGGGACCGCTTGTGCGACGTAGCGCTGCTACGTCTCCGCGCAGT
CCTTCGACAGCCTTGATCTT

Product: NADH-ubiquinone/plastoquinone oxidoreductase, chain 3

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A 1; NDH-1 subunit A 1; NUO1 1

Number of amino acids: Translated: 138; Mature: 138

Protein sequence:

>138_residues
MQQTTVANHSLFPTLPPEFLPLALYTVAATVLIGVLLLAAWWLGAKTTNRNKELPYESGVIPTGSARLAYPVPFYLIAIF
FIVFDVEAAFIFAWATAWRELGLAGLIHITFFIVILLLGLVWLWMKGGLDWGPSRERR

Sequences:

>Translated_138_residues
MQQTTVANHSLFPTLPPEFLPLALYTVAATVLIGVLLLAAWWLGAKTTNRNKELPYESGVIPTGSARLAYPVPFYLIAIF
FIVFDVEAAFIFAWATAWRELGLAGLIHITFFIVILLLGLVWLWMKGGLDWGPSRERR
>Mature_138_residues
MQQTTVANHSLFPTLPPEFLPLALYTVAATVLIGVLLLAAWWLGAKTTNRNKELPYESGVIPTGSARLAYPVPFYLIAIF
FIVFDVEAAFIFAWATAWRELGLAGLIHITFFIVILLLGLVWLWMKGGLDWGPSRERR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family

Homologues:

Organism=Escherichia coli, GI1788625, Length=118, Percent_Identity=44.9152542372881, Blast_Score=114, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOA1_GEOMG (Q39ZC5)

Other databases:

- EMBL:   CP000148
- RefSeq:   YP_383124.1
- STRING:   Q39ZC5
- GeneID:   3739633
- GenomeReviews:   CP000148_GR
- KEGG:   gme:Gmet_0152
- NMPDR:   fig|269799.3.peg.50
- eggNOG:   COG0838
- HOGENOM:   HBG605540
- OMA:   FIEATIF
- PhylomeDB:   Q39ZC5
- ProtClustDB:   CLSK829284
- BioCyc:   GMET269799:GMET_0152-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01394
- InterPro:   IPR023043
- InterPro:   IPR000440
- PANTHER:   PTHR11058

Pfam domain/function: PF00507 Oxidored_q4

EC number: =1.6.99.5

Molecular weight: Translated: 15462; Mature: 15462

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xd61cfa4)-; HASH(0xb7d2434)-; HASH(0xb808b4c)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQTTVANHSLFPTLPPEFLPLALYTVAATVLIGVLLLAAWWLGAKTTNRNKELPYESGV
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
IPTGSARLAYPVPFYLIAIFFIVFDVEAAFIFAWATAWRELGLAGLIHITFFIVILLLGL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VWLWMKGGLDWGPSRERR
HHHHHHCCCCCCCCCCCH
>Mature Secondary Structure
MQQTTVANHSLFPTLPPEFLPLALYTVAATVLIGVLLLAAWWLGAKTTNRNKELPYESGV
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
IPTGSARLAYPVPFYLIAIFFIVFDVEAAFIFAWATAWRELGLAGLIHITFFIVILLLGL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VWLWMKGGLDWGPSRERR
HHHHHHCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA