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The map label for this gene is ackA [H]

Identifier: 78221376

GI number: 78221376

Start: 180613

End: 181827

Strand: Direct

Name: ackA [H]

Synonym: Gmet_0149

Alternate gene names: 78221376

Gene position: 180613-181827 (Clockwise)

Preceding gene: 78221375

Following gene: 78221377

Centisome position: 4.52

GC content: 67.08

Gene sequence:

>1215_bases
ATGATTATCCTTATCCTGAACTGCCGGGGCTTTTCCATCCATTTCCAACTCTTCGACTGGTCCACCCGCACCATCCTCGC
CCGGGGGGACGTGGACCGGATCGAGCTGGGCGATTCCTTCATTGTCATGGAAGTCCCGGGCCGGGACCCCTACCATCTGG
ACTCGGACTGCTCCAGCTTCGGAGCCGCTGTGGCCCTCATCCTCTCCACCCTCACCCATCCCCTGGAGGGACCCCTTGAC
CGGGTCGAACAGATTGCCGCCGTGGGGCATCGGGTTGCCCATGGCGGCGAGCGGTTCACCTCGTCGGTCACCATCAACGA
AGAGATCATTGCGGCGGTCCGGGGATTCGAGGAGCTGGCACCGCTCCACATTCCCGCGAACCTGGCGGGGATCGAGGGGG
CCATGGCAACCCTTCCCCGCACCCCCCACGTGGCAGTCTTCGACTCGGCCTTCCATCAGACGATGCCCCTCCACGCCTAC
ATCTACCCCCTCCCCTGGGAGTGGTACGAAAAGCACGGCGTGCGACGCTATGGCTTCCACGGCGCACCCCACTGCTACGC
GGCGCAGCGGGGTGCGGCCCTCTTGGGGCGCGATCCGGCGGCATGCAACCTGGTCACCGTCCACATCGGCAATGGCACCT
CCCTCTGCGCCGTGGAGGGGGGACGCTCCATCGACACGAGCATGGGGCTCACCCCCCTGGAGGGGACCATGATGGGGACC
CGCTGCGGCTCCATCGATCCCGGCATCCCCCCCTTCATGATGCAGGAGGAGCAGCTTGCTCCCCGGGACATGGACCGGAT
CCTCAACCAGCGGAGCGGGGCAGCGGGAATCACCGGGCTGAAGCTGGATCGGGCTGCGTTCCTGGCCCGGGCCGCAGAAG
GAAACGAGCGGTGCCTCCTGGCCCTGGAGATGGAGGCCTACCGCCTCAAGAAGCACATCGGCGGCTACGCCGCGGCTCTC
GGCCGGCTCGACGCCGTGGTCTTCAGCACCGCCTCGGGGGAAGGGGAATGGCTCGTGCGGGAGAAGACCCTCGCCGACAT
GGAAATCTTCGGCATCCGGCTCGACCGGGAGCGGAACCGGGCGGCCCGTTCCGTGGAGCGGGAGGAGCGGATCAGCGCCG
ACGACTCCCCCGTGGCGGTCTACGTGGTCCACACCGAAGAAGAGATGGTCTATGCCGAGGAGGTGGCGGCCCTCCTGAAC
GGCGCCGGGGGATGA

Upstream 100 bases:

>100_bases
CGCCGCCGAGGAGAAAATCCAGGAGGCCATCGACGCCTGCCCGGTCTCCTGCATCCACTGGGGGTAGCCGGGCGCCAAAT
CCCATGAAACAGGAAGACCA

Downstream 100 bases:

>100_bases
CAAACGCCTGAAACGGGGTAAACTGTTTTTCTCACCGAATTCCATCCACCAAGGAGAGACTTATGTCGCTGGAAGGCAAA
CAAGCCCCCGACTTCACCCT

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase [H]

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MIILILNCRGFSIHFQLFDWSTRTILARGDVDRIELGDSFIVMEVPGRDPYHLDSDCSSFGAAVALILSTLTHPLEGPLD
RVEQIAAVGHRVAHGGERFTSSVTINEEIIAAVRGFEELAPLHIPANLAGIEGAMATLPRTPHVAVFDSAFHQTMPLHAY
IYPLPWEWYEKHGVRRYGFHGAPHCYAAQRGAALLGRDPAACNLVTVHIGNGTSLCAVEGGRSIDTSMGLTPLEGTMMGT
RCGSIDPGIPPFMMQEEQLAPRDMDRILNQRSGAAGITGLKLDRAAFLARAAEGNERCLLALEMEAYRLKKHIGGYAAAL
GRLDAVVFSTASGEGEWLVREKTLADMEIFGIRLDRERNRAARSVEREERISADDSPVAVYVVHTEEEMVYAEEVAALLN
GAGG

Sequences:

>Translated_404_residues
MIILILNCRGFSIHFQLFDWSTRTILARGDVDRIELGDSFIVMEVPGRDPYHLDSDCSSFGAAVALILSTLTHPLEGPLD
RVEQIAAVGHRVAHGGERFTSSVTINEEIIAAVRGFEELAPLHIPANLAGIEGAMATLPRTPHVAVFDSAFHQTMPLHAY
IYPLPWEWYEKHGVRRYGFHGAPHCYAAQRGAALLGRDPAACNLVTVHIGNGTSLCAVEGGRSIDTSMGLTPLEGTMMGT
RCGSIDPGIPPFMMQEEQLAPRDMDRILNQRSGAAGITGLKLDRAAFLARAAEGNERCLLALEMEAYRLKKHIGGYAAAL
GRLDAVVFSTASGEGEWLVREKTLADMEIFGIRLDRERNRAARSVEREERISADDSPVAVYVVHTEEEMVYAEEVAALLN
GAGG
>Mature_404_residues
MIILILNCRGFSIHFQLFDWSTRTILARGDVDRIELGDSFIVMEVPGRDPYHLDSDCSSFGAAVALILSTLTHPLEGPLD
RVEQIAAVGHRVAHGGERFTSSVTINEEIIAAVRGFEELAPLHIPANLAGIEGAMATLPRTPHVAVFDSAFHQTMPLHAY
IYPLPWEWYEKHGVRRYGFHGAPHCYAAQRGAALLGRDPAACNLVTVHIGNGTSLCAVEGGRSIDTSMGLTPLEGTMMGT
RCGSIDPGIPPFMMQEEQLAPRDMDRILNQRSGAAGITGLKLDRAAFLARAAEGNERCLLALEMEAYRLKKHIGGYAAAL
GRLDAVVFSTASGEGEWLVREKTLADMEIFGIRLDRERNRAARSVEREERISADDSPVAVYVVHTEEEMVYAEEVAALLN
GAGG

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family [H]

Homologues:

Organism=Escherichia coli, GI145693184, Length=391, Percent_Identity=40.153452685422, Blast_Score=287, Evalue=9e-79,
Organism=Escherichia coli, GI1788633, Length=404, Percent_Identity=37.6237623762376, Blast_Score=264, Evalue=7e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000890
- InterPro:   IPR004372 [H]

Pfam domain/function: PF00871 Acetate_kinase [H]

EC number: =2.7.2.1 [H]

Molecular weight: Translated: 44002; Mature: 44002

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIILILNCRGFSIHFQLFDWSTRTILARGDVDRIELGDSFIVMEVPGRDPYHLDSDCSSF
CEEEEEECCCEEEEEEEEECCCEEEEEECCCCEEEECCEEEEEECCCCCCCCCCCCHHHH
GAAVALILSTLTHPLEGPLDRVEQIAAVGHRVAHGGERFTSSVTINEEIIAAVRGFEELA
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHEEEEEECHHHHHHHHCHHHHC
PLHIPANLAGIEGAMATLPRTPHVAVFDSAFHQTMPLHAYIYPLPWEWYEKHGVRRYGFH
CEECCCCCCCCCCHHHHCCCCCCEEEECHHHHHCCCCEEEEECCCHHHHHHCCCEECCCC
GAPHCYAAQRGAALLGRDPAACNLVTVHIGNGTSLCAVEGGRSIDTSMGLTPLEGTMMGT
CCCCHHHHHCCCEEECCCCCCEEEEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCEEEC
RCGSIDPGIPPFMMQEEQLAPRDMDRILNQRSGAAGITGLKLDRAAFLARAAEGNERCLL
CCCCCCCCCCCCCCCHHHCCHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHCCCCCEEEE
ALEMEAYRLKKHIGGYAAALGRLDAVVFSTASGEGEWLVREKTLADMEIFGIRLDRERNR
EEEHHHHHHHHHHCHHHHHHHHHEEEEEEECCCCCCEEEEECCCCCEEEEEEEECCHHHH
AARSVEREERISADDSPVAVYVVHTEEEMVYAEEVAALLNGAGG
HHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIILILNCRGFSIHFQLFDWSTRTILARGDVDRIELGDSFIVMEVPGRDPYHLDSDCSSF
CEEEEEECCCEEEEEEEEECCCEEEEEECCCCEEEECCEEEEEECCCCCCCCCCCCHHHH
GAAVALILSTLTHPLEGPLDRVEQIAAVGHRVAHGGERFTSSVTINEEIIAAVRGFEELA
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHEEEEEECHHHHHHHHCHHHHC
PLHIPANLAGIEGAMATLPRTPHVAVFDSAFHQTMPLHAYIYPLPWEWYEKHGVRRYGFH
CEECCCCCCCCCCHHHHCCCCCCEEEECHHHHHCCCCEEEEECCCHHHHHHCCCEECCCC
GAPHCYAAQRGAALLGRDPAACNLVTVHIGNGTSLCAVEGGRSIDTSMGLTPLEGTMMGT
CCCCHHHHHCCCEEECCCCCCEEEEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCEEEC
RCGSIDPGIPPFMMQEEQLAPRDMDRILNQRSGAAGITGLKLDRAAFLARAAEGNERCLL
CCCCCCCCCCCCCCCHHHCCHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHCCCCCEEEE
ALEMEAYRLKKHIGGYAAALGRLDAVVFSTASGEGEWLVREKTLADMEIFGIRLDRERNR
EEEHHHHHHHHHHCHHHHHHHHHEEEEEEECCCCCCEEEEECCCCCEEEEEEEECCHHHH
AARSVEREERISADDSPVAVYVVHTEEEMVYAEEVAALLNGAGG
HHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA