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The map label for this gene is kynB [H]

Identifier: 78221270

GI number: 78221270

Start: 54982

End: 55662

Strand: Direct

Name: kynB [H]

Synonym: Gmet_0042

Alternate gene names: 78221270

Gene position: 54982-55662 (Clockwise)

Preceding gene: 78221269

Following gene: 78221271

Centisome position: 1.38

GC content: 67.84

Gene sequence:

>681_bases
ATGACAATCCACGACATCACGGTTCCCCTTTCTCCCGACCTCCCCGTCTACCCCGGCGACCCACCGGTCACCTGCGAGCC
GGTCACCCGCATCGCCCGGGGAGACACAGCCAACGTCACCCGCATTACCATGACCACCCACAGCGGCACCCACCTGGACG
TGCCGGGCCACTGCCGCGATGGCGGCGCCACCGTGGACCACCTCCCCCTCTCCCTTCTCATGGGGAAGGCCCGGGTGCTG
GACATCCGCGGCGAGCGGGCCATCGGCCGCCGTGAGCTTTCCCGTCTTCCGGTGCGGGGAGAGGAGCGGCTCCTCCTGCG
GACCGACAATTCCCTCCTCTGGGAGAGCCCCGGCTTCCAGGACGATTTTGCCCACCTCACCGAGGAGGGAGCCGCGTTTC
TCATCGAGGCGGGAGTCCGGCTTGTGGGGATCGACTACCTCTCCATCGAGGGAATCGCAAGCGGCATCACCGTCCACCGG
ATGCTCCTGGACGCGGGGGTTGTGATCCTGGAGGGGATCACCCTTGCCGAGGTGGAACCGGGTGAGTACGAACTGGTTTG
CCTTCCCCTTAAGATTGCCGGCGGGGACGGCGCTCCGGCCCGGGCCATCCTCCGGGGGAGGGAACCGAAGGGGGGAGAAA
CCCCCTTCGACCCCCACACGACCCGTTGGCCCGTGGCCTGA

Upstream 100 bases:

>100_bases
GTCTCCTTGCCGGGATTTCAGCAATGTAACGCCCGTCCTCGCAAATTCCTCCGCCGCGGGTATACTTTTCGGTGATTCCC
CCACGCAGCGGAGGCCAACC

Downstream 100 bases:

>100_bases
CAGGGGGCGTCATGGCAGGATCACGGAAGATCGTCAGCGCCCGGGAGCTGGACCTCCTGCGCCGCCTTCTCCGGGAACGG
ACCGAGGAGCTGGAGCGGGC

Product: putative cyclase

Products: NA

Alternate protein names: KFA; N-formylkynurenine formamidase [H]

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MTIHDITVPLSPDLPVYPGDPPVTCEPVTRIARGDTANVTRITMTTHSGTHLDVPGHCRDGGATVDHLPLSLLMGKARVL
DIRGERAIGRRELSRLPVRGEERLLLRTDNSLLWESPGFQDDFAHLTEEGAAFLIEAGVRLVGIDYLSIEGIASGITVHR
MLLDAGVVILEGITLAEVEPGEYELVCLPLKIAGGDGAPARAILRGREPKGGETPFDPHTTRWPVA

Sequences:

>Translated_226_residues
MTIHDITVPLSPDLPVYPGDPPVTCEPVTRIARGDTANVTRITMTTHSGTHLDVPGHCRDGGATVDHLPLSLLMGKARVL
DIRGERAIGRRELSRLPVRGEERLLLRTDNSLLWESPGFQDDFAHLTEEGAAFLIEAGVRLVGIDYLSIEGIASGITVHR
MLLDAGVVILEGITLAEVEPGEYELVCLPLKIAGGDGAPARAILRGREPKGGETPFDPHTTRWPVA
>Mature_225_residues
TIHDITVPLSPDLPVYPGDPPVTCEPVTRIARGDTANVTRITMTTHSGTHLDVPGHCRDGGATVDHLPLSLLMGKARVLD
IRGERAIGRRELSRLPVRGEERLLLRTDNSLLWESPGFQDDFAHLTEEGAAFLIEAGVRLVGIDYLSIEGIASGITVHRM
LLDAGVVILEGITLAEVEPGEYELVCLPLKIAGGDGAPARAILRGREPKGGETPFDPHTTRWPVA

Specific function: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine [H]

COG id: COG1878

COG function: function code R; Predicted metal-dependent hydrolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kynB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017484
- InterPro:   IPR007325 [H]

Pfam domain/function: PF04199 Cyclase [H]

EC number: =3.5.1.9 [H]

Molecular weight: Translated: 24367; Mature: 24236

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIHDITVPLSPDLPVYPGDPPVTCEPVTRIARGDTANVTRITMTTHSGTHLDVPGHCRD
CEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHCCCCCCEEEEEEEECCCCEECCCCCCCC
GGATVDHLPLSLLMGKARVLDIRGERAIGRRELSRLPVRGEERLLLRTDNSLLWESPGFQ
CCCCHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHCCCCCCCEEEEEECCCEEECCCCCC
DDFAHLTEEGAAFLIEAGVRLVGIDYLSIEGIASGITVHRMLLDAGVVILEGITLAEVEP
HHHHHHHHCCCEEEEECCCEEEEEEEEEECCHHCCHHHHHHHHHCCEEEECCEEEEEECC
GEYELVCLPLKIAGGDGAPARAILRGREPKGGETPFDPHTTRWPVA
CCEEEEEEEEEEECCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TIHDITVPLSPDLPVYPGDPPVTCEPVTRIARGDTANVTRITMTTHSGTHLDVPGHCRD
EEEEEEEECCCCCCCCCCCCCCCCHHHHHHHCCCCCCEEEEEEEECCCCEECCCCCCCC
GGATVDHLPLSLLMGKARVLDIRGERAIGRRELSRLPVRGEERLLLRTDNSLLWESPGFQ
CCCCHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHCCCCCCCEEEEEECCCEEECCCCCC
DDFAHLTEEGAAFLIEAGVRLVGIDYLSIEGIASGITVHRMLLDAGVVILEGITLAEVEP
HHHHHHHHCCCEEEEECCCEEEEEEEEEECCHHCCHHHHHHHHHCCEEEECCEEEEEECC
GEYELVCLPLKIAGGDGAPARAILRGREPKGGETPFDPHTTRWPVA
CCEEEEEEEEEEECCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA