Click here to switch to the map view.

The map label for this gene is hslO

Identifier: 78221269

GI number: 78221269

Start: 54005

End: 54910

Strand: Direct

Name: hslO

Synonym: Gmet_0041

Alternate gene names: 78221269

Gene position: 54005-54910 (Clockwise)

Preceding gene: 78221268

Following gene: 78221270

Centisome position: 1.35

GC content: 68.43

Gene sequence:

>906_bases
ATGGGAAACAGCACCGACTCGATCATCACCGACTATCTCGTCCGCGTCATCGCCAGGGACGGCAGCATCCGGGCTCTCGC
CTGCGTCACTACCGGCCTCGTGGGTGAGCTCTGCCGGCGCCACGGCACTTGGCCCACGGCCTCGGCGGCCCTGGGGCGGG
CCGTGACCGGCGGGGCCCTCATGGGAGCGCTCCTGAAGACCGGCCAGCGGGTGGCACTCCGCTTCGAGGGGAACGGCCCC
CTGAAGAATATCCTCGTGGAGGCCGACGCCAACGGCGCCGTCCGTGGCTGCGTGGGGAACCCGGAGGCGAACCCCCTGCG
GGAGGACGGCAAGCTGGATGTGGCCGCCGCCATCGGCCAGGCCGGGCTCCTCACCGTCACCAAGGACCTGGGGCTCAAGG
AGCCTTACACGGGGACGGTGCTCCTCTACACGAGCGAGATCGCCGAGGACCTCGCCTACTACCTGACCGACTCGGAGCAG
GTGCCGTCGGCGGTGGGGCTTGGGGTCTTCGTGGAGCCCGACGGCGCCGTCGCCGCTGCTGGCGGGTTCCTCATCCAGTC
GCTCCCCCCCCACAACGACGAAGCGGTGGACCGGCTCATGGAGCGGATCGGCGCCATGCCGCCGGTCACGGAGCTCCTCC
GGCAGGGGAAGAGCCCCGAGGGGCTCCTGGAGTACCTCTTCGAGGGGATCCCCTACGACACCCTGGAGAAGCGGGCACTG
GCCTTTGTCTGCTCCTGCAGTCGGGAGCGGATCGAGCGGGTTCTCATATCGCTTGGGCGTGACGACCTCGCCTCGCTCCT
GGCCGAACAGGGGGAGACCGAGGTGACCTGTGAGTTCTGTCGGGAGCACTACCATTTCGGCCGCGACGACCTTGAACGTC
TCCTTGCCGGGATTTCAGCAATGTAA

Upstream 100 bases:

>100_bases
CCCGGGAGCGGTGGCGCCCCATCCTCGACGCCCTTGCCCGGGGCGAGGGGGTGCCGGGGACGAGCGAATTCAACTTTGTC
ATGGGATTGGTATAGATACT

Downstream 100 bases:

>100_bases
CGCCCGTCCTCGCAAATTCCTCCGCCGCGGGTATACTTTTCGGTGATTCCCCCACGCAGCGGAGGCCAACCATGACAATC
CACGACATCACGGTTCCCCT

Product: Hsp33-like chaperonin

Products: NA

Alternate protein names: Heat shock protein 33 homolog; HSP33

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MGNSTDSIITDYLVRVIARDGSIRALACVTTGLVGELCRRHGTWPTASAALGRAVTGGALMGALLKTGQRVALRFEGNGP
LKNILVEADANGAVRGCVGNPEANPLREDGKLDVAAAIGQAGLLTVTKDLGLKEPYTGTVLLYTSEIAEDLAYYLTDSEQ
VPSAVGLGVFVEPDGAVAAAGGFLIQSLPPHNDEAVDRLMERIGAMPPVTELLRQGKSPEGLLEYLFEGIPYDTLEKRAL
AFVCSCSRERIERVLISLGRDDLASLLAEQGETEVTCEFCREHYHFGRDDLERLLAGISAM

Sequences:

>Translated_301_residues
MGNSTDSIITDYLVRVIARDGSIRALACVTTGLVGELCRRHGTWPTASAALGRAVTGGALMGALLKTGQRVALRFEGNGP
LKNILVEADANGAVRGCVGNPEANPLREDGKLDVAAAIGQAGLLTVTKDLGLKEPYTGTVLLYTSEIAEDLAYYLTDSEQ
VPSAVGLGVFVEPDGAVAAAGGFLIQSLPPHNDEAVDRLMERIGAMPPVTELLRQGKSPEGLLEYLFEGIPYDTLEKRAL
AFVCSCSRERIERVLISLGRDDLASLLAEQGETEVTCEFCREHYHFGRDDLERLLAGISAM
>Mature_300_residues
GNSTDSIITDYLVRVIARDGSIRALACVTTGLVGELCRRHGTWPTASAALGRAVTGGALMGALLKTGQRVALRFEGNGPL
KNILVEADANGAVRGCVGNPEANPLREDGKLDVAAAIGQAGLLTVTKDLGLKEPYTGTVLLYTSEIAEDLAYYLTDSEQV
PSAVGLGVFVEPDGAVAAAGGFLIQSLPPHNDEAVDRLMERIGAMPPVTELLRQGKSPEGLLEYLFEGIPYDTLEKRALA
FVCSCSRERIERVLISLGRDDLASLLAEQGETEVTCEFCREHYHFGRDDLERLLAGISAM

Specific function: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress

COG id: COG1281

COG function: function code O; Disulfide bond chaperones of the HSP33 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HSP33 family

Homologues:

Organism=Escherichia coli, GI87082260, Length=289, Percent_Identity=24.2214532871972, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSLO_GEOMG (Q39ZN3)

Other databases:

- EMBL:   CP000148
- RefSeq:   YP_383016.1
- ProteinModelPortal:   Q39ZN3
- SMR:   Q39ZN3
- STRING:   Q39ZN3
- GeneID:   3738529
- GenomeReviews:   CP000148_GR
- KEGG:   gme:Gmet_0041
- NMPDR:   fig|269799.3.peg.105
- eggNOG:   COG1281
- HOGENOM:   HBG286231
- OMA:   AMTIDQG
- PhylomeDB:   Q39ZN3
- ProtClustDB:   PRK00114
- BioCyc:   GMET269799:GMET_0041-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00117
- InterPro:   IPR000397
- InterPro:   IPR016154
- InterPro:   IPR016153
- Gene3D:   G3DSA:3.90.1280.10
- Gene3D:   G3DSA:3.55.30.10
- PIRSF:   PIRSF005261

Pfam domain/function: PF01430 HSP33; SSF64397 Heat_shock_Hsp33_N

EC number: NA

Molecular weight: Translated: 32104; Mature: 31973

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNSTDSIITDYLVRVIARDGSIRALACVTTGLVGELCRRHGTWPTASAALGRAVTGGAL
CCCCHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
MGALLKTGQRVALRFEGNGPLKNILVEADANGAVRGCVGNPEANPLREDGKLDVAAAIGQ
HHHHHHCCCEEEEEECCCCCHHHEEEECCCCCCEEECCCCCCCCCCCCCCCCHHHHHHCC
AGLLTVTKDLGLKEPYTGTVLLYTSEIAEDLAYYLTDSEQVPSAVGLGVFVEPDGAVAAA
CCCEEEHHHCCCCCCCCCEEEEEEHHHHHHHHHHHCCCHHCCHHHCCCEEECCCCCEECC
GGFLIQSLPPHNDEAVDRLMERIGAMPPVTELLRQGKSPEGLLEYLFEGIPYDTLEKRAL
CCHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHH
AFVCSCSRERIERVLISLGRDDLASLLAEQGETEVTCEFCREHYHFGRDDLERLLAGISA
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCC
M
C
>Mature Secondary Structure 
GNSTDSIITDYLVRVIARDGSIRALACVTTGLVGELCRRHGTWPTASAALGRAVTGGAL
CCCHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
MGALLKTGQRVALRFEGNGPLKNILVEADANGAVRGCVGNPEANPLREDGKLDVAAAIGQ
HHHHHHCCCEEEEEECCCCCHHHEEEECCCCCCEEECCCCCCCCCCCCCCCCHHHHHHCC
AGLLTVTKDLGLKEPYTGTVLLYTSEIAEDLAYYLTDSEQVPSAVGLGVFVEPDGAVAAA
CCCEEEHHHCCCCCCCCCEEEEEEHHHHHHHHHHHCCCHHCCHHHCCCEEECCCCCEECC
GGFLIQSLPPHNDEAVDRLMERIGAMPPVTELLRQGKSPEGLLEYLFEGIPYDTLEKRAL
CCHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHH
AFVCSCSRERIERVLISLGRDDLASLLAEQGETEVTCEFCREHYHFGRDDLERLLAGISA
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCC
M
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA