Click here to switch to the map view.

The map label for this gene is pckG [H]

Identifier: 78189965

GI number: 78189965

Start: 2551059

End: 2552951

Strand: Reverse

Name: pckG [H]

Synonym: Cag_2012

Alternate gene names: 78189965

Gene position: 2552951-2551059 (Counterclockwise)

Preceding gene: 78189966

Following gene: 78189963

Centisome position: 99.26

GC content: 48.71

Gene sequence:

>1893_bases
ATGAGCCTTATGAGTTCAATTTCCTTAAACCTTCCTGATTACATTCAGCACAAAAAGTTGATTCAGTGGGTGCAAGAAAC
TGCTGACCACTGCCAACCCGATGCTATCCATTGGTGCGATGGTTCGCAAGAGGAGTACGATTATTTGTGTGAGCAAATGG
TAGCAAGTGGCACCTTTATCAAGCTTTCCGAAGAGAAGCGTCCAAACAGCTACCTTTGCCGCTCCGACCCCAGCGATGTT
GCGCGTGTTGAGGATCGCACCTTTATTTGCAGTATTCGCCGTCAAGATGCTGGTCCTACCAACAACTGGGTGGCACCAAA
AGAGATGAAAGAGCAGTTGCATGAGCTTTTCCGCAATTGCATGAAAGGGCGCACGATGTATGTGATTCCTTTTAGCATGG
GACCGCTTGGCTCGCCGATTGCGCATATTGGTGTGGAAATTACTGATTCGCCTTACGTGGTAACCAACATGCGCATTATG
ACGCGCATGGGGCGAAAGGTGATGGATATACTTGGCGATAAAGGGGAGTTTGTGCCTTGCTTGCACTCGGTTGGTGCTCC
GCTTGAGCCCGGTCAGCAAGATGTGGCTTGGCCTTGCAATTCGACCAAATATATTACCCACTTTCCTGAGGAGCGTTCCA
TTATCTCCTTTGGTAGCGGCTACGGTGGTAATGCATTGCTTGGCAAAAAGTGCTTTGCTTTGCGCATTGCATCCTCAATG
GCACGCGATGAAGGGTGGCTTGCTGAGCATATGCTTATTCTTGGTGTAGAATCGCCCGATGGTGAAAAAACCTACGTTGG
TGCTGCTTTCCCAAGTGCGTGTGGTAAAACCAATTTTGCCATGCTTATTCCCCCAAAATCATTTGATGGGTGGAAAATTA
CCACCATTGGCGACGACATTGCATGGATTAAGCAAGGTGAAGATGGCTACCTTTATGCCATTAATCCCGAACATGGCTTT
TTTGGCGTAGCGCCCGGTACTTCAGAGAAATCGAATCCTAACGCTATGGCAACGTTGCGTGCAAACTGCATTTATACCAA
CGTGGCATTAACGCCCGATGGCGATGTGTGGTGGGAAGGCATGACGGATGAAAAACCTGAGCGTCTTATTGATTGGCAGG
GGTATGAGTGGACACCTGATTGCGGACGTCTTGCAGCGCATCCCAATGCTCGCTTTACCTCACCCGCAAGCCAGTGCCCA
TCGCTTGACCCTGCATGGGAAGACCCCAATGGTGTACAAATTAGCGCCTTTATTTTTGGTGGTCGTCGTGGTTCTACGGT
GCCACTTGTCTATCAATCACCCAACTGGATGTTTGGCGTTTATCTTGCAGCCACTATGGGGTCCGAAAAAACCGCTGCGG
CTGCGGGCAAAGTGGGCGAAGTTCGCCGCGATCCTTATGCCATGCTACCATTCTGCGGCTATCACATGGGCGATTACTTT
AACCATTGGCTTCACATTGGGCGCACGTTACCTGAGTTGCCTCGTATTTTTGGGGTAAACTGGTTCCGTAAAGATGAAAA
TGGCAATTTCCTATGGCCTGGTTTTGGCGAAAATATGCGCGTCTTAAAATGGATGATTGATCGTGTGCGTGGCAATGCTG
GTGCTGTTGAAAGTCCGCTTGGTTGGATGCCGAAGTATGATATGATTGATTGGACAGGGCTTGAAGAGATGACCGAAGAG
AAATTTGCTGAGCTGATGTCGGTTGATAGGGAAGCGTGGAAAAAAGAGCTGTTGTCGCACGAAGCACTCTTTGAAATGAT
TTACGATCGCTTACCAAAAGAGTTTAGCCACATTCGTGAGCTGATGCTTTCAACGCTTTGGATGTCGCCCGCAAAATGGT
CGTTAGCGCCAGAACACTACTCAGCAGATCACGATGTTGAAGATGAAGAGTAA

Upstream 100 bases:

>100_bases
TTTTTTTTGTACAGGTTTGTAGCGCTGCCTTGTTTTCTGCATTGTTCCCTCATTGTTTTTCTTTTCTTCATCAACCAAAT
GCCTTAGCGCACTTATCCCC

Downstream 100 bases:

>100_bases
GGGAATTTCCTTTATTACTACAACAAAAAGGCGCCTACTGTGGGCGCCTTTTTGTATTGCATGAACAAGAGGTTGAATTA
CAACGTCTCATTTTCTTCAA

Product: phosphoenolpyruvate carboxykinase

Products: NA

Alternate protein names: PEP carboxykinase; PEPCK; Phosphoenolpyruvate carboxylase [H]

Number of amino acids: Translated: 630; Mature: 629

Protein sequence:

>630_residues
MSLMSSISLNLPDYIQHKKLIQWVQETADHCQPDAIHWCDGSQEEYDYLCEQMVASGTFIKLSEEKRPNSYLCRSDPSDV
ARVEDRTFICSIRRQDAGPTNNWVAPKEMKEQLHELFRNCMKGRTMYVIPFSMGPLGSPIAHIGVEITDSPYVVTNMRIM
TRMGRKVMDILGDKGEFVPCLHSVGAPLEPGQQDVAWPCNSTKYITHFPEERSIISFGSGYGGNALLGKKCFALRIASSM
ARDEGWLAEHMLILGVESPDGEKTYVGAAFPSACGKTNFAMLIPPKSFDGWKITTIGDDIAWIKQGEDGYLYAINPEHGF
FGVAPGTSEKSNPNAMATLRANCIYTNVALTPDGDVWWEGMTDEKPERLIDWQGYEWTPDCGRLAAHPNARFTSPASQCP
SLDPAWEDPNGVQISAFIFGGRRGSTVPLVYQSPNWMFGVYLAATMGSEKTAAAAGKVGEVRRDPYAMLPFCGYHMGDYF
NHWLHIGRTLPELPRIFGVNWFRKDENGNFLWPGFGENMRVLKWMIDRVRGNAGAVESPLGWMPKYDMIDWTGLEEMTEE
KFAELMSVDREAWKKELLSHEALFEMIYDRLPKEFSHIRELMLSTLWMSPAKWSLAPEHYSADHDVEDEE

Sequences:

>Translated_630_residues
MSLMSSISLNLPDYIQHKKLIQWVQETADHCQPDAIHWCDGSQEEYDYLCEQMVASGTFIKLSEEKRPNSYLCRSDPSDV
ARVEDRTFICSIRRQDAGPTNNWVAPKEMKEQLHELFRNCMKGRTMYVIPFSMGPLGSPIAHIGVEITDSPYVVTNMRIM
TRMGRKVMDILGDKGEFVPCLHSVGAPLEPGQQDVAWPCNSTKYITHFPEERSIISFGSGYGGNALLGKKCFALRIASSM
ARDEGWLAEHMLILGVESPDGEKTYVGAAFPSACGKTNFAMLIPPKSFDGWKITTIGDDIAWIKQGEDGYLYAINPEHGF
FGVAPGTSEKSNPNAMATLRANCIYTNVALTPDGDVWWEGMTDEKPERLIDWQGYEWTPDCGRLAAHPNARFTSPASQCP
SLDPAWEDPNGVQISAFIFGGRRGSTVPLVYQSPNWMFGVYLAATMGSEKTAAAAGKVGEVRRDPYAMLPFCGYHMGDYF
NHWLHIGRTLPELPRIFGVNWFRKDENGNFLWPGFGENMRVLKWMIDRVRGNAGAVESPLGWMPKYDMIDWTGLEEMTEE
KFAELMSVDREAWKKELLSHEALFEMIYDRLPKEFSHIRELMLSTLWMSPAKWSLAPEHYSADHDVEDEE
>Mature_629_residues
SLMSSISLNLPDYIQHKKLIQWVQETADHCQPDAIHWCDGSQEEYDYLCEQMVASGTFIKLSEEKRPNSYLCRSDPSDVA
RVEDRTFICSIRRQDAGPTNNWVAPKEMKEQLHELFRNCMKGRTMYVIPFSMGPLGSPIAHIGVEITDSPYVVTNMRIMT
RMGRKVMDILGDKGEFVPCLHSVGAPLEPGQQDVAWPCNSTKYITHFPEERSIISFGSGYGGNALLGKKCFALRIASSMA
RDEGWLAEHMLILGVESPDGEKTYVGAAFPSACGKTNFAMLIPPKSFDGWKITTIGDDIAWIKQGEDGYLYAINPEHGFF
GVAPGTSEKSNPNAMATLRANCIYTNVALTPDGDVWWEGMTDEKPERLIDWQGYEWTPDCGRLAAHPNARFTSPASQCPS
LDPAWEDPNGVQISAFIFGGRRGSTVPLVYQSPNWMFGVYLAATMGSEKTAAAAGKVGEVRRDPYAMLPFCGYHMGDYFN
HWLHIGRTLPELPRIFGVNWFRKDENGNFLWPGFGENMRVLKWMIDRVRGNAGAVESPLGWMPKYDMIDWTGLEEMTEEK
FAELMSVDREAWKKELLSHEALFEMIYDRLPKEFSHIRELMLSTLWMSPAKWSLAPEHYSADHDVEDEE

Specific function: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle [H]

COG id: COG1274

COG function: function code C; Phosphoenolpyruvate carboxykinase (GTP)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family [H]

Homologues:

Organism=Homo sapiens, GI187281517, Length=596, Percent_Identity=51.8456375838926, Blast_Score=605, Evalue=1e-173,
Organism=Homo sapiens, GI66346721, Length=587, Percent_Identity=52.6405451448041, Blast_Score=599, Evalue=1e-171,
Organism=Homo sapiens, GI66346723, Length=374, Percent_Identity=54.8128342245989, Blast_Score=399, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI71989645, Length=592, Percent_Identity=49.6621621621622, Blast_Score=565, Evalue=1e-161,
Organism=Caenorhabditis elegans, GI71989658, Length=592, Percent_Identity=49.6621621621622, Blast_Score=564, Evalue=1e-161,
Organism=Caenorhabditis elegans, GI71989653, Length=579, Percent_Identity=50.259067357513, Blast_Score=558, Evalue=1e-159,
Organism=Caenorhabditis elegans, GI17555492, Length=585, Percent_Identity=49.2307692307692, Blast_Score=555, Evalue=1e-158,
Organism=Caenorhabditis elegans, GI32564411, Length=554, Percent_Identity=50.1805054151625, Blast_Score=540, Evalue=1e-153,
Organism=Caenorhabditis elegans, GI32564407, Length=493, Percent_Identity=51.9269776876268, Blast_Score=500, Evalue=1e-142,
Organism=Caenorhabditis elegans, GI71989649, Length=483, Percent_Identity=51.75983436853, Blast_Score=491, Evalue=1e-139,
Organism=Caenorhabditis elegans, GI32564409, Length=338, Percent_Identity=48.5207100591716, Blast_Score=321, Evalue=8e-88,
Organism=Caenorhabditis elegans, GI17540956, Length=517, Percent_Identity=25.3384912959381, Blast_Score=154, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24655085, Length=575, Percent_Identity=51.6521739130435, Blast_Score=600, Evalue=1e-171,
Organism=Drosophila melanogaster, GI24655082, Length=596, Percent_Identity=50.503355704698, Blast_Score=587, Evalue=1e-167,
Organism=Drosophila melanogaster, GI161077226, Length=565, Percent_Identity=51.3274336283186, Blast_Score=560, Evalue=1e-159,
Organism=Drosophila melanogaster, GI24655088, Length=480, Percent_Identity=53.75, Blast_Score=522, Evalue=1e-148,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018091
- InterPro:   IPR013035
- InterPro:   IPR008209
- InterPro:   IPR008210 [H]

Pfam domain/function: PF00821 PEPCK [H]

EC number: =4.1.1.32 [H]

Molecular weight: Translated: 71140; Mature: 71008

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00505 PEPCK_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLMSSISLNLPDYIQHKKLIQWVQETADHCQPDAIHWCDGSQEEYDYLCEQMVASGTFI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHCCCEE
KLSEEKRPNSYLCRSDPSDVARVEDRTFICSIRRQDAGPTNNWVAPKEMKEQLHELFRNC
EECCCCCCCCCCCCCCCHHHHHHCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHH
MKGRTMYVIPFSMGPLGSPIAHIGVEITDSPYVVTNMRIMTRMGRKVMDILGDKGEFVPC
HCCCEEEEEEECCCCCCCCHHHEEEEECCCCEEEEHHHHHHHHHHHHHHHHCCCCCCHHH
LHSVGAPLEPGQQDVAWPCNSTKYITHFPEERSIISFGSGYGGNALLGKKCFALRIASSM
HHHCCCCCCCCCCCCCCCCCCCCEEEECCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHH
ARDEGWLAEHMLILGVESPDGEKTYVGAAFPSACGKTNFAMLIPPKSFDGWKITTIGDDI
HHCCCHHEEEEEEEEECCCCCCCEEEECCCCCCCCCCCEEEEECCCCCCCEEEEEECCCE
AWIKQGEDGYLYAINPEHGFFGVAPGTSEKSNPNAMATLRANCIYTNVALTPDGDVWWEG
EEEEECCCCEEEEECCCCCEEECCCCCCCCCCCCEEEEEEEEEEEEEEEECCCCCEEECC
MTDEKPERLIDWQGYEWTPDCGRLAAHPNARFTSPASQCPSLDPAWEDPNGVQISAFIFG
CCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCEEEEEEEE
GRRGSTVPLVYQSPNWMFGVYLAATMGSEKTAAAAGKVGEVRRDPYAMLPFCGYHMGDYF
CCCCCEEEEEECCCCEEEEEEEEECCCCCHHHHHHCCHHHHCCCCCEECCHHHHHHHHHH
NHWLHIGRTLPELPRIFGVNWFRKDENGNFLWPGFGENMRVLKWMIDRVRGNAGAVESPL
HHHHHHHCHHHHHHHHHCCCEEEECCCCCEECCCCCCCHHHHHHHHHHHCCCCCCCCCCC
GWMPKYDMIDWTGLEEMTEEKFAELMSVDREAWKKELLSHEALFEMIYDRLPKEFSHIRE
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
LMLSTLWMSPAKWSLAPEHYSADHDVEDEE
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SLMSSISLNLPDYIQHKKLIQWVQETADHCQPDAIHWCDGSQEEYDYLCEQMVASGTFI
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHCCCEE
KLSEEKRPNSYLCRSDPSDVARVEDRTFICSIRRQDAGPTNNWVAPKEMKEQLHELFRNC
EECCCCCCCCCCCCCCCHHHHHHCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHH
MKGRTMYVIPFSMGPLGSPIAHIGVEITDSPYVVTNMRIMTRMGRKVMDILGDKGEFVPC
HCCCEEEEEEECCCCCCCCHHHEEEEECCCCEEEEHHHHHHHHHHHHHHHHCCCCCCHHH
LHSVGAPLEPGQQDVAWPCNSTKYITHFPEERSIISFGSGYGGNALLGKKCFALRIASSM
HHHCCCCCCCCCCCCCCCCCCCCEEEECCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHH
ARDEGWLAEHMLILGVESPDGEKTYVGAAFPSACGKTNFAMLIPPKSFDGWKITTIGDDI
HHCCCHHEEEEEEEEECCCCCCCEEEECCCCCCCCCCCEEEEECCCCCCCEEEEEECCCE
AWIKQGEDGYLYAINPEHGFFGVAPGTSEKSNPNAMATLRANCIYTNVALTPDGDVWWEG
EEEEECCCCEEEEECCCCCEEECCCCCCCCCCCCEEEEEEEEEEEEEEEECCCCCEEECC
MTDEKPERLIDWQGYEWTPDCGRLAAHPNARFTSPASQCPSLDPAWEDPNGVQISAFIFG
CCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCEEEEEEEE
GRRGSTVPLVYQSPNWMFGVYLAATMGSEKTAAAAGKVGEVRRDPYAMLPFCGYHMGDYF
CCCCCEEEEEECCCCEEEEEEEEECCCCCHHHHHHCCHHHHCCCCCEECCHHHHHHHHHH
NHWLHIGRTLPELPRIFGVNWFRKDENGNFLWPGFGENMRVLKWMIDRVRGNAGAVESPL
HHHHHHHCHHHHHHHHHCCCEEEECCCCCEECCCCCCCHHHHHHHHHHHCCCCCCCCCCC
GWMPKYDMIDWTGLEEMTEEKFAELMSVDREAWKKELLSHEALFEMIYDRLPKEFSHIRE
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
LMLSTLWMSPAKWSLAPEHYSADHDVEDEE
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]