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The map label for this gene is resA [H]

Identifier: 78189966

GI number: 78189966

Start: 2553185

End: 2553715

Strand: Reverse

Name: resA [H]

Synonym: Cag_2013

Alternate gene names: 78189966

Gene position: 2553715-2553185 (Counterclockwise)

Preceding gene: 78189972

Following gene: 78189965

Centisome position: 99.29

GC content: 41.43

Gene sequence:

>531_bases
ATGAAACTTTTGCGCTCACTTACTGCCACAATTGTTTGTAGTTTGCTGTTCCTTTCAGTCCCTGCGGTAATGCAAGCTGC
CCCAAAAGCGCCAGCTTTTAGTGCCGTATCAGTAACGGGTAAAGCTACTGATACAAAGCAGCTTGCAGGTAAAACTTATA
TTGTTAATTTTTTTGCATCGTGGTGTCCGCCCTGCCGTGCTGAAATTCCTGATATGGTGGCATTACAAAATAAGTACAGT
AAAAAAGGGTTTACCTTTGTTGGTATTGCCGTTAATGAGGATGCTGAAAACATTCGTTCCTTTATCACAAAAAATAACAT
TAACTATCCCGTTGTTATGGCAACGCCCGAATTAGTTGATTCCTATAATCGCTACGTGCAAGGTGGGTTACGTGGTATTC
CCACTTCGTTTGTGGTAAATAGCTCGGGTGAAATAACGCAGGTAATTTCAGGTGGACGTAGTTATGCGGAGTTTGAGAAA
ATTATTCTTGGTGCCATGAAAAAATCAACGGTTGCCGCACCTAAAAAGTAA

Upstream 100 bases:

>100_bases
CGAAACTTTTGCTCTCTTCTCTCTCTTTTTTAAAAATTCTTGGTATTCCCCAACTGTTCTTCCCTATTGTTATAAATAAT
TCTTTAAAATTTTGTTTGTA

Downstream 100 bases:

>100_bases
CGGATTGCCCCTCTTCTTCTTATTATGACCAAATGGTTCCACGCTTGTGGAGCGTTCATGCCACGCCGCAATACCTCTCT
TTTTCTGCACGTCCGCAGGG

Product: thiol:disulfide interchange protein, thioredoxin family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MKLLRSLTATIVCSLLFLSVPAVMQAAPKAPAFSAVSVTGKATDTKQLAGKTYIVNFFASWCPPCRAEIPDMVALQNKYS
KKGFTFVGIAVNEDAENIRSFITKNNINYPVVMATPELVDSYNRYVQGGLRGIPTSFVVNSSGEITQVISGGRSYAEFEK
IILGAMKKSTVAAPKK

Sequences:

>Translated_176_residues
MKLLRSLTATIVCSLLFLSVPAVMQAAPKAPAFSAVSVTGKATDTKQLAGKTYIVNFFASWCPPCRAEIPDMVALQNKYS
KKGFTFVGIAVNEDAENIRSFITKNNINYPVVMATPELVDSYNRYVQGGLRGIPTSFVVNSSGEITQVISGGRSYAEFEK
IILGAMKKSTVAAPKK
>Mature_176_residues
MKLLRSLTATIVCSLLFLSVPAVMQAAPKAPAFSAVSVTGKATDTKQLAGKTYIVNFFASWCPPCRAEIPDMVALQNKYS
KKGFTFVGIAVNEDAENIRSFITKNNINYPVVMATPELVDSYNRYVQGGLRGIPTSFVVNSSGEITQVISGGRSYAEFEK
IILGAMKKSTVAAPKK

Specific function: Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalent

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein. Note=The thioredoxin-like motif is exposed on the outside of the membrane (By similarity) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00578 AhpC-TSA [H]

EC number: NA

Molecular weight: Translated: 18993; Mature: 18993

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLRSLTATIVCSLLFLSVPAVMQAAPKAPAFSAVSVTGKATDTKQLAGKTYIVNFFAS
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHCCHHHHHHHHH
WCPPCRAEIPDMVALQNKYSKKGFTFVGIAVNEDAENIRSFITKNNINYPVVMATPELVD
HCCCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHCCCCCCCEEEECHHHHH
SYNRYVQGGLRGIPTSFVVNSSGEITQVISGGRSYAEFEKIILGAMKKSTVAAPKK
HHHHHHHCCCCCCCCEEEECCCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKLLRSLTATIVCSLLFLSVPAVMQAAPKAPAFSAVSVTGKATDTKQLAGKTYIVNFFAS
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHCCHHHHHHHHH
WCPPCRAEIPDMVALQNKYSKKGFTFVGIAVNEDAENIRSFITKNNINYPVVMATPELVD
HCCCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHCCCCCCCEEEECHHHHH
SYNRYVQGGLRGIPTSFVVNSSGEITQVISGGRSYAEFEKIILGAMKKSTVAAPKK
HHHHHHHCCCCCCCCEEEECCCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]