Click here to switch to the map view.

The map label for this gene is aroA

Identifier: 78189589

GI number: 78189589

Start: 2129790

End: 2131097

Strand: Reverse

Name: aroA

Synonym: Cag_1631

Alternate gene names: 78189589

Gene position: 2131097-2129790 (Counterclockwise)

Preceding gene: 78189590

Following gene: 78189583

Centisome position: 82.86

GC content: 49.54

Gene sequence:

>1308_bases
ATGCGAGTTTTTCGAGGTGAAGTAACCACCTTGCCGCCCGATAAATCCATTTCACATCGTGCAGCTATGATTGCTGCCCT
TTCGGAAGGCACTACTGAAATCACCAATTTCTCAGCAGGTTTCGATAACCAATCCACGCTTGGCGTGTTGCGCAATGCGG
GCATTGTGGTGCAGCAAGAGGAAGTGCAAGGCGCACACGGTCGTACCATGCGGCGCGTTGTAATTACCTCCAATGGATTG
TGGAGTTTTACACCACCAACGGCACCGTTGCAATGCAACAATTCGGGTAGCACCATGCGTATGATGTCGGGCATTCTTGC
CGCTCAGCCCTTTCAATGCACCTTAATTGGTGATGCATCGCTCATGAAGCGCCCCATGAAGCGCGTTGCCGATCCACTTC
GCCAAATGGGTGCCACCATTGAGCTTTCGCCCGATGGCACAGCGCCAATCCATATCAGTGGCACTAAAGAGCTTCGCTCT
CTTGAATACCGCCTTCCCGTTGCATCAGCGCAAGTAAAATCGCTTATTGCTTTTGCGGCACTGCACGCAGAGGGCGAAAC
ACGCATTATTGAGCCGCTGCAATCGCGAGACCACACGGAAGTGATGCTTGGGCTTGAAACGATTGTAAAAAAAGATGAGC
GCATTATTGTGGTGCCCGGTCAGCAACGCATTGCAGCAAAACCATTTTTTATTCCAGCCGACCCAAGTGCCGCATGTTTT
ATTATTGCTTTAGGATTGCTGGCTCGTGGCTCTGAAATCGTTATTCGCGATGTTTGCCTCAATCCAACCCGTGCCGCTTA
TCTTGATCTTTTAGCGGAAGCGAAAGCTGGTATTGGTGTTGATAATCAGCGCGTTATTGGGGGAGAAATTATTGGCGATA
TTCTTATTGACAACCTCAATGGCATTGAGCCACTCCACATTAGCGATCCACAGCTTGTTGCCTTTATTATTGATGAAATT
CCCATGTTAGCTGTGCTATCAGCCTTTGCAACAGGCTCCTTTGAGCTGCATAATGCTGCCGAGCTTCGCACCAAAGAGAG
CGACCGCATTGAAGCCTTAGTGGTAAATTTGCAACGGCTTGGTTTTGCATGCGAACAATATCCCGATGGCTTTGTGGTCA
AAAAGCGCACCGAAGTGCCGCAGGGCAAGGTTACCATTGAAAGCTTTGATGACCACCGCATTGCCATGAGCTTTGCTATT
GCCGCACAAGCTACCGGCGAAGCGCTCGATATTAGCGATATTGAAGTGGTTGGTGTCTCCTTCCCCAACTTTTTTTCGCT
CCTTGAAGAGCTTTCAAGCGAAGCGTAA

Upstream 100 bases:

>100_bases
AGCGTAACTCTTAAGCTGGTTTTTACTTTTGATTCTATCTCTAAAAAAAGCAACTTTGTTATGAGGTTGCTTTTTTTATT
AACTCATAGTTTTTCAACCC

Downstream 100 bases:

>100_bases
CTAATTCCCCCACATTCTCCCTTCCCCCCAAAAAAAAGCGCTGCCGTTCACGTATGATGGCAGCGCTTTGGTGGAAATGA
TTTGTATAGCGTGGTTACTT

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MRVFRGEVTTLPPDKSISHRAAMIAALSEGTTEITNFSAGFDNQSTLGVLRNAGIVVQQEEVQGAHGRTMRRVVITSNGL
WSFTPPTAPLQCNNSGSTMRMMSGILAAQPFQCTLIGDASLMKRPMKRVADPLRQMGATIELSPDGTAPIHISGTKELRS
LEYRLPVASAQVKSLIAFAALHAEGETRIIEPLQSRDHTEVMLGLETIVKKDERIIVVPGQQRIAAKPFFIPADPSAACF
IIALGLLARGSEIVIRDVCLNPTRAAYLDLLAEAKAGIGVDNQRVIGGEIIGDILIDNLNGIEPLHISDPQLVAFIIDEI
PMLAVLSAFATGSFELHNAAELRTKESDRIEALVVNLQRLGFACEQYPDGFVVKKRTEVPQGKVTIESFDDHRIAMSFAI
AAQATGEALDISDIEVVGVSFPNFFSLLEELSSEA

Sequences:

>Translated_435_residues
MRVFRGEVTTLPPDKSISHRAAMIAALSEGTTEITNFSAGFDNQSTLGVLRNAGIVVQQEEVQGAHGRTMRRVVITSNGL
WSFTPPTAPLQCNNSGSTMRMMSGILAAQPFQCTLIGDASLMKRPMKRVADPLRQMGATIELSPDGTAPIHISGTKELRS
LEYRLPVASAQVKSLIAFAALHAEGETRIIEPLQSRDHTEVMLGLETIVKKDERIIVVPGQQRIAAKPFFIPADPSAACF
IIALGLLARGSEIVIRDVCLNPTRAAYLDLLAEAKAGIGVDNQRVIGGEIIGDILIDNLNGIEPLHISDPQLVAFIIDEI
PMLAVLSAFATGSFELHNAAELRTKESDRIEALVVNLQRLGFACEQYPDGFVVKKRTEVPQGKVTIESFDDHRIAMSFAI
AAQATGEALDISDIEVVGVSFPNFFSLLEELSSEA
>Mature_435_residues
MRVFRGEVTTLPPDKSISHRAAMIAALSEGTTEITNFSAGFDNQSTLGVLRNAGIVVQQEEVQGAHGRTMRRVVITSNGL
WSFTPPTAPLQCNNSGSTMRMMSGILAAQPFQCTLIGDASLMKRPMKRVADPLRQMGATIELSPDGTAPIHISGTKELRS
LEYRLPVASAQVKSLIAFAALHAEGETRIIEPLQSRDHTEVMLGLETIVKKDERIIVVPGQQRIAAKPFFIPADPSAACF
IIALGLLARGSEIVIRDVCLNPTRAAYLDLLAEAKAGIGVDNQRVIGGEIIGDILIDNLNGIEPLHISDPQLVAFIIDEI
PMLAVLSAFATGSFELHNAAELRTKESDRIEALVVNLQRLGFACEQYPDGFVVKKRTEVPQGKVTIESFDDHRIAMSFAI
AAQATGEALDISDIEVVGVSFPNFFSLLEELSSEA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family

Homologues:

Organism=Escherichia coli, GI1787137, Length=440, Percent_Identity=25.2272727272727, Blast_Score=92, Evalue=9e-20,
Organism=Saccharomyces cerevisiae, GI6320332, Length=458, Percent_Identity=24.235807860262, Blast_Score=87, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROA_CHLCH (Q3AQ41)

Other databases:

- EMBL:   CP000108
- RefSeq:   YP_379927.1
- STRING:   Q3AQ41
- GeneID:   3747939
- GenomeReviews:   CP000108_GR
- KEGG:   cch:Cag_1631
- eggNOG:   COG0128
- HOGENOM:   HBG646626
- OMA:   LSRNHTE
- ProtClustDB:   PRK02427
- BioCyc:   CCHL340177:CAG_1631-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00210
- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792
- Gene3D:   G3DSA:3.65.10.10
- PIRSF:   PIRSF000505
- TIGRFAMs:   TIGR01356

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.19

Molecular weight: Translated: 47023; Mature: 47023

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00104 EPSP_SYNTHASE_1; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVFRGEVTTLPPDKSISHRAAMIAALSEGTTEITNFSAGFDNQSTLGVLRNAGIVVQQE
CCEECCCCEECCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHCCCEEEEHH
EVQGAHGRTMRRVVITSNGLWSFTPPTAPLQCNNSGSTMRMMSGILAAQPFQCTLIGDAS
HCCCCCCCEEEEEEEECCCEEEECCCCCCEEECCCCCHHHHHHHHHHCCCEEEEEECCHH
LMKRPMKRVADPLRQMGATIELSPDGTAPIHISGTKELRSLEYRLPVASAQVKSLIAFAA
HHHHHHHHHHHHHHHCCCEEEECCCCCCCEEECCHHHHHHHHEECCCHHHHHHHHHHHHH
LHAEGETRIIEPLQSRDHTEVMLGLETIVKKDERIIVVPGQQRIAAKPFFIPADPSAACF
HHCCCCCHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCHHCCCCEEEECCCCHHHH
IIALGLLARGSEIVIRDVCLNPTRAAYLDLLAEAKAGIGVDNQRVIGGEIIGDILIDNLN
HHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCEEECHHHHHHHHHHCCC
GIEPLHISDPQLVAFIIDEIPMLAVLSAFATGSFELHNAAELRTKESDRIEALVVNLQRL
CCCCEECCCCHHHHHHHHCCHHHHHHHHHHCCCEEECCHHHHCCCCCHHHHHHHHHHHHH
GFACEQYPDGFVVKKRTEVPQGKVTIESFDDHRIAMSFAIAAQATGEALDISDIEVVGVS
CCHHHHCCCCEEEEECCCCCCCCEEEECCCCCEEEEEEEEEECCCCCEECCCCEEEEEEC
FPNFFSLLEELSSEA
CHHHHHHHHHHHCCC
>Mature Secondary Structure
MRVFRGEVTTLPPDKSISHRAAMIAALSEGTTEITNFSAGFDNQSTLGVLRNAGIVVQQE
CCEECCCCEECCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHCCCEEEEHH
EVQGAHGRTMRRVVITSNGLWSFTPPTAPLQCNNSGSTMRMMSGILAAQPFQCTLIGDAS
HCCCCCCCEEEEEEEECCCEEEECCCCCCEEECCCCCHHHHHHHHHHCCCEEEEEECCHH
LMKRPMKRVADPLRQMGATIELSPDGTAPIHISGTKELRSLEYRLPVASAQVKSLIAFAA
HHHHHHHHHHHHHHHCCCEEEECCCCCCCEEECCHHHHHHHHEECCCHHHHHHHHHHHHH
LHAEGETRIIEPLQSRDHTEVMLGLETIVKKDERIIVVPGQQRIAAKPFFIPADPSAACF
HHCCCCCHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCHHCCCCEEEECCCCHHHH
IIALGLLARGSEIVIRDVCLNPTRAAYLDLLAEAKAGIGVDNQRVIGGEIIGDILIDNLN
HHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCEEECHHHHHHHHHHCCC
GIEPLHISDPQLVAFIIDEIPMLAVLSAFATGSFELHNAAELRTKESDRIEALVVNLQRL
CCCCEECCCCHHHHHHHHCCHHHHHHHHHHCCCEEECCHHHHCCCCCHHHHHHHHHHHHH
GFACEQYPDGFVVKKRTEVPQGKVTIESFDDHRIAMSFAIAAQATGEALDISDIEVVGVS
CCHHHHCCCCEEEEECCCCCCCCEEEECCCCCEEEEEEEEEECCCCCEECCCCEEEEEEC
FPNFFSLLEELSSEA
CHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA