Click here to switch to the map view.

The map label for this gene is lolC [H]

Identifier: 78188887

GI number: 78188887

Start: 1250109

End: 1251350

Strand: Reverse

Name: lolC [H]

Synonym: Cag_0919

Alternate gene names: 78188887

Gene position: 1251350-1250109 (Counterclockwise)

Preceding gene: 78188888

Following gene: 78188885

Centisome position: 48.65

GC content: 47.67

Gene sequence:

>1242_bases
ATGTGCATGAAACCTGCCCTTTGGATTGCCCTCCGCTTTAGCTTTGCCCGCAAACGCTTTCGCATTATTAACTTTATATC
GGCAATTACCCTTGCAGGCATTACCATAGGCGTAGCAACGCTGTTGGTGGTTTTGAGTGTTTTGAACGGTTTTCAAGAAC
TGGCTCGCACCTTTTTTCTCTCTCTTGAAAGCCCCGTGCAGCTTGTTAGCTCTCACAACAACGCCATTACCGTAACACCC
GCACTTTTAGCAAGCATTCGCACCCTTGAGGGCGTTGCCACTGCCGAGCCGTATGCCGAAGGTGAAGCGTTGCTTGCCAC
TCAAAATAAGAGCGAATTAGTGATGCTTAAAGGGTTATCGCCAACGGCTCATCAACATTTACAGAACTACATTAATGCTC
CGCAACCTCTCTTTACCGATAGCACTATAGCGGTAGGGGAGCTGCTTGCCTTGCGCTCTTCACTCTATCCAAACCAACCA
ATACAACTCTTTAGCCCCGAATTACTCTCGCTGGGGCTGGAGTCGCTTACCCAACCCTACTTGATTGCAGCACTTACCAT
TCCTCGCACTTCACTGCACACCATCTTTTCAATCCACAAACTTTTTGACGACCGCTACGCTCTCAGCAGTTTGCCACTTG
CTCGCCAAGTGCTGCTTCTCGGCGATAATAACTATACAGGGATTGAGATTCGAGGAAAGCACGGAGTGAAGGGAGAAACC
TTGCAGCGCACTCTTCAGCAGTGGCTTACAAAAGAGGGAGTGGAAAAAAGCTACCGCATCCGCACGCTTGAGGAAAAATA
CCAAAGCGTTTTTTCGGTGATGCAGCTTGAAAAATGGATAACCTTCAGCATTCTCATGTTAGTGATTGTGCTTGCTTCAC
TTAGCCTAACGGGATCGCTTGCTATGACCGTTGTTGAAAAACAGCAAGAGCTTTTTTATCTCCGCTGCCTTGGCTTCAAC
ACCCCATCATTTACAGCACTTTTTGTAATGCAAGGAGCAATAACGGGCATTACAGGCACCACACTTGGTACCGCACTTGG
ATGGGGAATTTGTGCAGCGCAGCAACATTTTGGATTTGTACAATTGCCCTCACGCACCGCATTTATTATTGATGCCTATC
CAGTCGCCATGCAACTAAGCGACTTTTTTGTTGTGGGAGGAGCAGCAATTGCACTCTGCCTTATTGTAAGCTTATATCCT
GCTCGAAAAGCTGCCCTTATTGCAAGTAGCCGCACGGTTTGA

Upstream 100 bases:

>100_bases
CGTTTTAGCGCTCTGCCTCCTTTTTGCATGGCTACCTTCAACCATTGCAGCCTCCCTAAAACCAGCTCGTGCGTTAGACG
CATAAACTTTTTGTTTGTTA

Downstream 100 bases:

>100_bases
GGGAGAATATGGATAAACTTATAATGCCCACACGATTGAGAGACGTGGTATCATCATCAATCGTATAGGCATTATTTTGT
GGAAATAGCTTCTTACAAAC

Product: ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MCMKPALWIALRFSFARKRFRIINFISAITLAGITIGVATLLVVLSVLNGFQELARTFFLSLESPVQLVSSHNNAITVTP
ALLASIRTLEGVATAEPYAEGEALLATQNKSELVMLKGLSPTAHQHLQNYINAPQPLFTDSTIAVGELLALRSSLYPNQP
IQLFSPELLSLGLESLTQPYLIAALTIPRTSLHTIFSIHKLFDDRYALSSLPLARQVLLLGDNNYTGIEIRGKHGVKGET
LQRTLQQWLTKEGVEKSYRIRTLEEKYQSVFSVMQLEKWITFSILMLVIVLASLSLTGSLAMTVVEKQQELFYLRCLGFN
TPSFTALFVMQGAITGITGTTLGTALGWGICAAQQHFGFVQLPSRTAFIIDAYPVAMQLSDFFVVGGAAIALCLIVSLYP
ARKAALIASSRTV

Sequences:

>Translated_413_residues
MCMKPALWIALRFSFARKRFRIINFISAITLAGITIGVATLLVVLSVLNGFQELARTFFLSLESPVQLVSSHNNAITVTP
ALLASIRTLEGVATAEPYAEGEALLATQNKSELVMLKGLSPTAHQHLQNYINAPQPLFTDSTIAVGELLALRSSLYPNQP
IQLFSPELLSLGLESLTQPYLIAALTIPRTSLHTIFSIHKLFDDRYALSSLPLARQVLLLGDNNYTGIEIRGKHGVKGET
LQRTLQQWLTKEGVEKSYRIRTLEEKYQSVFSVMQLEKWITFSILMLVIVLASLSLTGSLAMTVVEKQQELFYLRCLGFN
TPSFTALFVMQGAITGITGTTLGTALGWGICAAQQHFGFVQLPSRTAFIIDAYPVAMQLSDFFVVGGAAIALCLIVSLYP
ARKAALIASSRTV
>Mature_413_residues
MCMKPALWIALRFSFARKRFRIINFISAITLAGITIGVATLLVVLSVLNGFQELARTFFLSLESPVQLVSSHNNAITVTP
ALLASIRTLEGVATAEPYAEGEALLATQNKSELVMLKGLSPTAHQHLQNYINAPQPLFTDSTIAVGELLALRSSLYPNQP
IQLFSPELLSLGLESLTQPYLIAALTIPRTSLHTIFSIHKLFDDRYALSSLPLARQVLLLGDNNYTGIEIRGKHGVKGET
LQRTLQQWLTKEGVEKSYRIRTLEEKYQSVFSVMQLEKWITFSILMLVIVLASLSLTGSLAMTVVEKQQELFYLRCLGFN
TPSFTALFVMQGAITGITGTTLGTALGWGICAAQQHFGFVQLPSRTAFIIDAYPVAMQLSDFFVVGGAAIALCLIVSLYP
ARKAALIASSRTV

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=437, Percent_Identity=25.629290617849, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1787360, Length=409, Percent_Identity=26.4058679706601, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 45259; Mature: 45259

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCMKPALWIALRFSFARKRFRIINFISAITLAGITIGVATLLVVLSVLNGFQELARTFFL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLESPVQLVSSHNNAITVTPALLASIRTLEGVATAEPYAEGEALLATQNKSELVMLKGLS
HCCCHHHHHHCCCCEEEECHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCEEEEECCC
PTAHQHLQNYINAPQPLFTDSTIAVGELLALRSSLYPNQPIQLFSPELLSLGLESLTQPY
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHCCCE
LIAALTIPRTSLHTIFSIHKLFDDRYALSSLPLARQVLLLGDNNYTGIEIRGKHGVKGET
EEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEECCCEEEEEEECCCCCCCHH
LQRTLQQWLTKEGVEKSYRIRTLEEKYQSVFSVMQLEKWITFSILMLVIVLASLSLTGSL
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
AMTVVEKQQELFYLRCLGFNTPSFTALFVMQGAITGITGTTLGTALGWGICAAQQHFGFV
HHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEE
QLPSRTAFIIDAYPVAMQLSDFFVVGGAAIALCLIVSLYPARKAALIASSRTV
ECCCCEEEEEECCHHHHHHHHHHEEHHHHHHHHHHHHHCCCHHHHHHHCCCCC
>Mature Secondary Structure
MCMKPALWIALRFSFARKRFRIINFISAITLAGITIGVATLLVVLSVLNGFQELARTFFL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLESPVQLVSSHNNAITVTPALLASIRTLEGVATAEPYAEGEALLATQNKSELVMLKGLS
HCCCHHHHHHCCCCEEEECHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCEEEEECCC
PTAHQHLQNYINAPQPLFTDSTIAVGELLALRSSLYPNQPIQLFSPELLSLGLESLTQPY
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHCCCE
LIAALTIPRTSLHTIFSIHKLFDDRYALSSLPLARQVLLLGDNNYTGIEIRGKHGVKGET
EEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEECCCEEEEEEECCCCCCCHH
LQRTLQQWLTKEGVEKSYRIRTLEEKYQSVFSVMQLEKWITFSILMLVIVLASLSLTGSL
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
AMTVVEKQQELFYLRCLGFNTPSFTALFVMQGAITGITGTTLGTALGWGICAAQQHFGFV
HHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEE
QLPSRTAFIIDAYPVAMQLSDFFVVGGAAIALCLIVSLYPARKAALIASSRTV
ECCCCEEEEEECCHHHHHHHHHHEEHHHHHHHHHHHHHCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]