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The map label for this gene is lolC [H]

Identifier: 78188888

GI number: 78188888

Start: 1251366

End: 1252634

Strand: Reverse

Name: lolC [H]

Synonym: Cag_0920

Alternate gene names: 78188888

Gene position: 1252634-1251366 (Counterclockwise)

Preceding gene: 78188889

Following gene: 78188887

Centisome position: 48.7

GC content: 47.12

Gene sequence:

>1269_bases
ATGAAACTTCTGTGGTACCTTGCAACCCGCTTTGCCTTAAAACAGCGCTCCAGCTCAAAACCAACCTTTGTGGTAGTTTT
AGCAGTTGCAGGTATTGCCGCAGGCACCGCGGCGTTGCTCTTAACGCTTGCCATTGTTAACGGTTTTGCGGCAACCATTT
CCCAAAAGTTAGTGAGCTTTAATGCCCATTTACAGCTTCGCCATAGTAGCCAAGAATTTTTTCAAGAGGAGCGCTCCGAA
CGTTTGCAACTTACCTCGCATCCCGAAATAACGCACTTCACCCCTTTTCTTGAACAACGCTTTGTGTTACGGTGTCGCAA
TAGTGCCCAGCAAGGGCGATGGTCAAGCAAAGCAGTGTTGGTAAAAGCTATGCCATCGGCTGAACGCCAAAATTTTATAA
AGCGCTATAGCGTAAGGGGAGAGGAGAAAGAATGCCGTGTGGCTGAAGGGATGGTTGGTATTTATCTTGGGCGCTCTTTA
GCGGAGGAACTGAATTGCAAGGTGGGGCAAAAAGTAATGCTGATTCGTGATAGCAATCAAGCCTCGCAGCGCCTACTTGC
TGATGCTACCAGCCTCCCCGAACTGCTTGCCTCGCTTGCTATTGAACCTGCCGTAGTGTGCGGTATTTACAGCACAGGTT
TGCAAGAGGGATTTGATGATTACCTCTTGCTTGCCGATTTATCGGCATTGGAGCAAAGCCGTAAAGGTTTTATTAGCGGC
TACGAAGCCAATGTTCGCCATATAGAGCGTTTGCCTACCACCGTGCAAGAGTTAACTGCTCTTACCAACAATCGCCTCTA
CGGCTACACGCTTTTTCAACGCTATGCTAATTTATTTGAATGGATTAAGTTACAGCAAAACATTATGCCACTCTTAATTG
TTACCATCACCGTTGTGGCAGTCTTTAATATTATGGCAACGCTTTTAGTGCTCATTATTGAAAAAACGGGCGAAATTGGA
ATGCTGAGCGCTCTTGGTTTAGCGCCGCAGCGCATTCAAGGGTTGTTTATGCTTCAAGCGCTCCTGCTTTCAATAACGGG
TATTACACTTGGCAACTTGCTGGCGTTGGGGCTGGCGTTGTTTGAACAGCACTACCACCTCATTCGCCTTCCTGAAAAAA
GTTACTTTATTACCGAAGTGCAGCTTTTACTTAACCCGATGGATAACGTTGTGGTGTCGCTGAGCGTTTTAGCGCTCTGC
CTCCTTTTTGCATGGCTACCTTCAACCATTGCAGCCTCCCTAAAACCAGCTCGTGCGTTAGACGCATAA

Upstream 100 bases:

>100_bases
TAGAATAAATTCTTGGGGAACTGAAGCGATAAAAAGCAGTTTCTTAGAAATTCATAAATCTTTTGTTATAACTTTTTGAG
CGCTTATTTATTCCCCCTCT

Downstream 100 bases:

>100_bases
ACTTTTTGTTTGTTAATGTGCATGAAACCTGCCCTTTGGATTGCCCTCCGCTTTAGCTTTGCCCGCAAACGCTTTCGCAT
TATTAACTTTATATCGGCAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MKLLWYLATRFALKQRSSSKPTFVVVLAVAGIAAGTAALLLTLAIVNGFAATISQKLVSFNAHLQLRHSSQEFFQEERSE
RLQLTSHPEITHFTPFLEQRFVLRCRNSAQQGRWSSKAVLVKAMPSAERQNFIKRYSVRGEEKECRVAEGMVGIYLGRSL
AEELNCKVGQKVMLIRDSNQASQRLLADATSLPELLASLAIEPAVVCGIYSTGLQEGFDDYLLLADLSALEQSRKGFISG
YEANVRHIERLPTTVQELTALTNNRLYGYTLFQRYANLFEWIKLQQNIMPLLIVTITVVAVFNIMATLLVLIIEKTGEIG
MLSALGLAPQRIQGLFMLQALLLSITGITLGNLLALGLALFEQHYHLIRLPEKSYFITEVQLLLNPMDNVVVSLSVLALC
LLFAWLPSTIAASLKPARALDA

Sequences:

>Translated_422_residues
MKLLWYLATRFALKQRSSSKPTFVVVLAVAGIAAGTAALLLTLAIVNGFAATISQKLVSFNAHLQLRHSSQEFFQEERSE
RLQLTSHPEITHFTPFLEQRFVLRCRNSAQQGRWSSKAVLVKAMPSAERQNFIKRYSVRGEEKECRVAEGMVGIYLGRSL
AEELNCKVGQKVMLIRDSNQASQRLLADATSLPELLASLAIEPAVVCGIYSTGLQEGFDDYLLLADLSALEQSRKGFISG
YEANVRHIERLPTTVQELTALTNNRLYGYTLFQRYANLFEWIKLQQNIMPLLIVTITVVAVFNIMATLLVLIIEKTGEIG
MLSALGLAPQRIQGLFMLQALLLSITGITLGNLLALGLALFEQHYHLIRLPEKSYFITEVQLLLNPMDNVVVSLSVLALC
LLFAWLPSTIAASLKPARALDA
>Mature_422_residues
MKLLWYLATRFALKQRSSSKPTFVVVLAVAGIAAGTAALLLTLAIVNGFAATISQKLVSFNAHLQLRHSSQEFFQEERSE
RLQLTSHPEITHFTPFLEQRFVLRCRNSAQQGRWSSKAVLVKAMPSAERQNFIKRYSVRGEEKECRVAEGMVGIYLGRSL
AEELNCKVGQKVMLIRDSNQASQRLLADATSLPELLASLAIEPAVVCGIYSTGLQEGFDDYLLLADLSALEQSRKGFISG
YEANVRHIERLPTTVQELTALTNNRLYGYTLFQRYANLFEWIKLQQNIMPLLIVTITVVAVFNIMATLLVLIIEKTGEIG
MLSALGLAPQRIQGLFMLQALLLSITGITLGNLLALGLALFEQHYHLIRLPEKSYFITEVQLLLNPMDNVVVSLSVLALC
LLFAWLPSTIAASLKPARALDA

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=437, Percent_Identity=24.0274599542334, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1787360, Length=431, Percent_Identity=24.1299303944316, Blast_Score=76, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 46896; Mature: 46896

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLWYLATRFALKQRSSSKPTFVVVLAVAGIAAGTAALLLTLAIVNGFAATISQKLVSF
CHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NAHLQLRHSSQEFFQEERSERLQLTSHPEITHFTPFLEQRFVLRCRNSAQQGRWSSKAVL
CCEEEEECCHHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHHCCHHCCCCCCCEEE
VKAMPSAERQNFIKRYSVRGEEKECRVAEGMVGIYLGRSLAEELNCKVGQKVMLIRDSNQ
EEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCH
ASQRLLADATSLPELLASLAIEPAVVCGIYSTGLQEGFDDYLLLADLSALEQSRKGFISG
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCC
YEANVRHIERLPTTVQELTALTNNRLYGYTLFQRYANLFEWIKLQQNIMPLLIVTITVVA
CHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFNIMATLLVLIIEKTGEIGMLSALGLAPQRIQGLFMLQALLLSITGITLGNLLALGLAL
HHHHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FEQHYHLIRLPEKSYFITEVQLLLNPMDNVVVSLSVLALCLLFAWLPSTIAASLKPARAL
HHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHC
DA
CC
>Mature Secondary Structure
MKLLWYLATRFALKQRSSSKPTFVVVLAVAGIAAGTAALLLTLAIVNGFAATISQKLVSF
CHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NAHLQLRHSSQEFFQEERSERLQLTSHPEITHFTPFLEQRFVLRCRNSAQQGRWSSKAVL
CCEEEEECCHHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHHCCHHCCCCCCCEEE
VKAMPSAERQNFIKRYSVRGEEKECRVAEGMVGIYLGRSLAEELNCKVGQKVMLIRDSNQ
EEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCH
ASQRLLADATSLPELLASLAIEPAVVCGIYSTGLQEGFDDYLLLADLSALEQSRKGFISG
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCC
YEANVRHIERLPTTVQELTALTNNRLYGYTLFQRYANLFEWIKLQQNIMPLLIVTITVVA
CHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFNIMATLLVLIIEKTGEIGMLSALGLAPQRIQGLFMLQALLLSITGITLGNLLALGLAL
HHHHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FEQHYHLIRLPEKSYFITEVQLLLNPMDNVVVSLSVLALCLLFAWLPSTIAASLKPARAL
HHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHC
DA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]