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The map label for this gene is leuE [H]

Identifier: 78067945

GI number: 78067945

Start: 3644452

End: 3645087

Strand: Reverse

Name: leuE [H]

Synonym: Bcep18194_A6476

Alternate gene names: 78067945

Gene position: 3645087-3644452 (Counterclockwise)

Preceding gene: 78067946

Following gene: 78067944

Centisome position: 98.67

GC content: 66.67

Gene sequence:

>636_bases
ATGTTCGGCATCACCCATTTCGGCTTCTTCGTGCTGGCAGTCTTCCTGCTGAACGTCACGCCCGGCCCCGATACGGCCTA
TATCGTTGGCCGCAGCGTCGCGCAGGGCCGCGGCGCGGGGCTGATGTCGGCGTTCGGCATTTCGGCCGGCTGCTGCGTTC
ACGCGCTCGCCTGCGCATTCGGCCTGACCGCGCTGCTTGCGGCGTCGGCTGCCGCATTCACGGTGATCAAGCTGGTCGGC
GCCGCCTACCTGATCTACCTCGGCGTGCGGATGATCTTCGCGAAGCAGGCGGCCGAGCCGTCGGGCAAGGCGGCCACCCA
AGCCGCGAAGCCGCTGCGCCAGCTGTTCATGCAGGGCTTCTGGACCAACGTGCTGAACCCGAAGGTCGTGCTGTTCTTCG
TGTCGTTCTTCCCGCAGTTCGTGTCGGCCGACAGCCCGCACAAGGCATTGGCGTTCCTGACCCTCGGCGGCGTGTTTGTC
GCGATGAGCACGGTGTGGACCAGTCTCGTCGCGTGGGTCGCGGGCAGTGTCACGGAGCGCTTCTCCGGCAAGCCGGGCGT
CAAGAAGTGGCTCGACCGCACGGTCGGCAGCGCGTTCGTCGGCCTCGGCCTTCGTCTTGCAACATCGCAACGCTGA

Upstream 100 bases:

>100_bases
ACACGGCCTGCCGGGCGTGCGCAATCGGCCGGACGGCCGAGTCGCGCGGTGCGGCAGGCGCGCGTAGAATTTCCCTGCGC
TCTCCGGTTTCGAGGTTCTC

Downstream 100 bases:

>100_bases
GATTGAATTTTTCCGGCAAGACCTTATCTAACAAATCGCTTACAATTTTCCGCCGCGCCCTTTGATGCGCGGCGGGCCCC
CTGACGGATAAGGAGTGGGT

Product: lysine exporter protein LysE/YggA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MFGITHFGFFVLAVFLLNVTPGPDTAYIVGRSVAQGRGAGLMSAFGISAGCCVHALACAFGLTALLAASAAAFTVIKLVG
AAYLIYLGVRMIFAKQAAEPSGKAATQAAKPLRQLFMQGFWTNVLNPKVVLFFVSFFPQFVSADSPHKALAFLTLGGVFV
AMSTVWTSLVAWVAGSVTERFSGKPGVKKWLDRTVGSAFVGLGLRLATSQR

Sequences:

>Translated_211_residues
MFGITHFGFFVLAVFLLNVTPGPDTAYIVGRSVAQGRGAGLMSAFGISAGCCVHALACAFGLTALLAASAAAFTVIKLVG
AAYLIYLGVRMIFAKQAAEPSGKAATQAAKPLRQLFMQGFWTNVLNPKVVLFFVSFFPQFVSADSPHKALAFLTLGGVFV
AMSTVWTSLVAWVAGSVTERFSGKPGVKKWLDRTVGSAFVGLGLRLATSQR
>Mature_211_residues
MFGITHFGFFVLAVFLLNVTPGPDTAYIVGRSVAQGRGAGLMSAFGISAGCCVHALACAFGLTALLAASAAAFTVIKLVG
AAYLIYLGVRMIFAKQAAEPSGKAATQAAKPLRQLFMQGFWTNVLNPKVVLFFVSFFPQFVSADSPHKALAFLTLGGVFV
AMSTVWTSLVAWVAGSVTERFSGKPGVKKWLDRTVGSAFVGLGLRLATSQR

Specific function: Exporter of leucine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI1788099, Length=209, Percent_Identity=27.2727272727273, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI48994979, Length=210, Percent_Identity=28.0952380952381, Blast_Score=85, Evalue=3e-18,
Organism=Escherichia coli, GI48994978, Length=197, Percent_Identity=28.4263959390863, Blast_Score=70, Evalue=9e-14,
Organism=Escherichia coli, GI1786522, Length=160, Percent_Identity=29.375, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 22220; Mature: 22220

Theoretical pI: Translated: 10.93; Mature: 10.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGITHFGFFVLAVFLLNVTPGPDTAYIVGRSVAQGRGAGLMSAFGISAGCCVHALACAF
CCCHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHHCCCCCCHHHHHCCCHHHHHHHHHHHH
GLTALLAASAAAFTVIKLVGAAYLIYLGVRMIFAKQAAEPSGKAATQAAKPLRQLFMQGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
WTNVLNPKVVLFFVSFFPQFVSADSPHKALAFLTLGGVFVAMSTVWTSLVAWVAGSVTER
HHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSGKPGVKKWLDRTVGSAFVGLGLRLATSQR
HCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MFGITHFGFFVLAVFLLNVTPGPDTAYIVGRSVAQGRGAGLMSAFGISAGCCVHALACAF
CCCHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHHCCCCCCHHHHHCCCHHHHHHHHHHHH
GLTALLAASAAAFTVIKLVGAAYLIYLGVRMIFAKQAAEPSGKAATQAAKPLRQLFMQGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
WTNVLNPKVVLFFVSFFPQFVSADSPHKALAFLTLGGVFVAMSTVWTSLVAWVAGSVTER
HHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSGKPGVKKWLDRTVGSAFVGLGLRLATSQR
HCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA