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The map label for this gene is fmt

Identifier: 78067946

GI number: 78067946

Start: 3645208

End: 3646191

Strand: Reverse

Name: fmt

Synonym: Bcep18194_A6477

Alternate gene names: 78067946

Gene position: 3646191-3645208 (Counterclockwise)

Preceding gene: 78067947

Following gene: 78067945

Centisome position: 98.7

GC content: 71.54

Gene sequence:

>984_bases
ATGACCCATACGTTGCGCGTAGTTTTTGCCGGCACGCCGGAATTCGCCGCGGCTGCCCTCGCCGCGATCCACGAGGCCGG
TTTTCCGGTGCCGCTCGTGCTCACCCAGCCCGATCGCCCTGCCGGGCGCGGGATGAAATTGCAGGCCAGCGCGGTGAAGC
GCTACGCCGTCGAGCACGGGATGCCCGTTGCGCAACCGCCGTCGCTGCGCCGCGCGGGCAAGTACCCGGCGGAGGCGGCC
GACGCGATTGAGCTGCTGCGCTCGACCCCGCATGACGTGATGGTGGTCGCCGCATACGGCTTGCTACTGCCGCAGGAAGT
GCTCGACATTCCGCGTGACGGCTGCATCAACATTCACGCGTCGCTGCTGCCGCGCTGGCGCGGCGCCGCGCCGATCCACC
GCGCGATCGAGGCCGGCGACGCCGAAACGGGCGTCACGCTGATGCAGATGGACATCGGCCTCGACACCGGCGCGATGATC
GAGGAAGCGCGCATCGCGATCGCGCCCGACGAGACGACCGCAACGCTGCACGACCGGCTCGCCGCCGAAGGTGCGCGACT
GATCGTCGACGCGCTCGTGCAGCTCGAGCGCGACGGCGTGCTGCCGGCGACGCCGCAACCGGCCGACGGCGTGACCTATG
CGGAAAAGATCGGCAAGCACGAAGCGGCGCTCGACTGGCGCAAGCCGGCCGACGTGCTCGCGCGCCAGGTGCGTGCGTTC
GATCCGTTCCCGGGCGGCGTCGCGACGCTCGACGGCGCGGCGATCAAGCTGTGGGCAGCCGAGCCGGTGGCGGCGCGCGG
CGAAGCAGCGCCCGGCACGATCGTCGAAGCCGCGCCGGAAGGCGTGGTCGTTGCGTGCGGCAGCGGTGCGTTGCGCGTCA
CGCAGTTGCAGAAGCCGGGCGGCAAGCGGCTGCCCGCGCGCGAATTCCTGGCCGGCTCGCCGCTCGCCGCAGGCCAGCGC
TTCGCGCTGACTGACGTTGCCTGA

Upstream 100 bases:

>100_bases
TACCTGTCGCCGCTCAAGCAGACGCGCATCAAGACGAAGATGAAGAAACTCGAACGCGCGATGTAACGCGCGTTCGCCCA
GCCCGATCCCGAACGCTGTC

Downstream 100 bases:

>100_bases
CGCGGCCTGACCGCCATTCGACACGGCCTGCCGGGCGTGCGCAATCGGCCGGACGGCCGAGTCGCGCGGTGCGGCAGGCG
CGCGTAGAATTTCCCTGCGC

Product: methionyl-tRNA formyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MTHTLRVVFAGTPEFAAAALAAIHEAGFPVPLVLTQPDRPAGRGMKLQASAVKRYAVEHGMPVAQPPSLRRAGKYPAEAA
DAIELLRSTPHDVMVVAAYGLLLPQEVLDIPRDGCINIHASLLPRWRGAAPIHRAIEAGDAETGVTLMQMDIGLDTGAMI
EEARIAIAPDETTATLHDRLAAEGARLIVDALVQLERDGVLPATPQPADGVTYAEKIGKHEAALDWRKPADVLARQVRAF
DPFPGGVATLDGAAIKLWAAEPVAARGEAAPGTIVEAAPEGVVVACGSGALRVTQLQKPGGKRLPAREFLAGSPLAAGQR
FALTDVA

Sequences:

>Translated_327_residues
MTHTLRVVFAGTPEFAAAALAAIHEAGFPVPLVLTQPDRPAGRGMKLQASAVKRYAVEHGMPVAQPPSLRRAGKYPAEAA
DAIELLRSTPHDVMVVAAYGLLLPQEVLDIPRDGCINIHASLLPRWRGAAPIHRAIEAGDAETGVTLMQMDIGLDTGAMI
EEARIAIAPDETTATLHDRLAAEGARLIVDALVQLERDGVLPATPQPADGVTYAEKIGKHEAALDWRKPADVLARQVRAF
DPFPGGVATLDGAAIKLWAAEPVAARGEAAPGTIVEAAPEGVVVACGSGALRVTQLQKPGGKRLPAREFLAGSPLAAGQR
FALTDVA
>Mature_326_residues
THTLRVVFAGTPEFAAAALAAIHEAGFPVPLVLTQPDRPAGRGMKLQASAVKRYAVEHGMPVAQPPSLRRAGKYPAEAAD
AIELLRSTPHDVMVVAAYGLLLPQEVLDIPRDGCINIHASLLPRWRGAAPIHRAIEAGDAETGVTLMQMDIGLDTGAMIE
EARIAIAPDETTATLHDRLAAEGARLIVDALVQLERDGVLPATPQPADGVTYAEKIGKHEAALDWRKPADVLARQVRAFD
PFPGGVATLDGAAIKLWAAEPVAARGEAAPGTIVEAAPEGVVVACGSGALRVTQLQKPGGKRLPAREFLAGSPLAAGQRF
ALTDVA

Specific function: Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by:(I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-

COG id: COG0223

COG function: function code J; Methionyl-tRNA formyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fmt family [H]

Homologues:

Organism=Homo sapiens, GI238814322, Length=323, Percent_Identity=29.7213622291022, Blast_Score=138, Evalue=5e-33,
Organism=Homo sapiens, GI21614513, Length=321, Percent_Identity=27.7258566978193, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI164663775, Length=245, Percent_Identity=32.2448979591837, Blast_Score=100, Evalue=1e-21,
Organism=Escherichia coli, GI1789683, Length=310, Percent_Identity=49.3548387096774, Blast_Score=280, Evalue=7e-77,
Organism=Escherichia coli, GI1788589, Length=316, Percent_Identity=30.0632911392405, Blast_Score=142, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI133930964, Length=337, Percent_Identity=26.7062314540059, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI45550868, Length=316, Percent_Identity=29.4303797468354, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI28571984, Length=275, Percent_Identity=30.1818181818182, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24585660, Length=253, Percent_Identity=27.2727272727273, Blast_Score=79, Evalue=4e-15,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005794
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR001555
- InterPro:   IPR015518 [H]

Pfam domain/function: PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]

EC number: =2.1.2.9 [H]

Molecular weight: Translated: 34226; Mature: 34095

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHTLRVVFAGTPEFAAAALAAIHEAGFPVPLVLTQPDRPAGRGMKLQASAVKRYAVEHG
CCCEEEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEHHHHHHHHHHHCC
MPVAQPPSLRRAGKYPAEAADAIELLRSTPHDVMVVAAYGLLLPQEVLDIPRDGCINIHA
CCCCCCCCHHHCCCCCHHHHHHHHHHHCCCCCEEHHHHHHHHCCHHHHCCCCCCEEEEHH
SLLPRWRGAAPIHRAIEAGDAETGVTLMQMDIGLDTGAMIEEARIAIAPDETTATLHDRL
HHCCCCCCCCHHHHHHHCCCCCCCEEEEEEECCCCCCCHHCCCEEEECCCCCHHHHHHHH
AAEGARLIVDALVQLERDGVLPATPQPADGVTYAEKIGKHEAALDWRKPADVLARQVRAF
HHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCHHHHCCCCCCHHHHHHHHHHC
DPFPGGVATLDGAAIKLWAAEPVAARGEAAPGTIVEAAPEGVVVACGSGALRVTQLQKPG
CCCCCCEEEECCCEEEEEECCCCCCCCCCCCCCEEECCCCCEEEEECCCCEEEEEECCCC
GKRLPAREFLAGSPLAAGQRFALTDVA
CCCCCHHHHHCCCCCCCCCEEEEECCC
>Mature Secondary Structure 
THTLRVVFAGTPEFAAAALAAIHEAGFPVPLVLTQPDRPAGRGMKLQASAVKRYAVEHG
CCEEEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEHHHHHHHHHHHCC
MPVAQPPSLRRAGKYPAEAADAIELLRSTPHDVMVVAAYGLLLPQEVLDIPRDGCINIHA
CCCCCCCCHHHCCCCCHHHHHHHHHHHCCCCCEEHHHHHHHHCCHHHHCCCCCCEEEEHH
SLLPRWRGAAPIHRAIEAGDAETGVTLMQMDIGLDTGAMIEEARIAIAPDETTATLHDRL
HHCCCCCCCCHHHHHHHCCCCCCCEEEEEEECCCCCCCHHCCCEEEECCCCCHHHHHHHH
AAEGARLIVDALVQLERDGVLPATPQPADGVTYAEKIGKHEAALDWRKPADVLARQVRAF
HHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCHHHHCCCCCCHHHHHHHHHHC
DPFPGGVATLDGAAIKLWAAEPVAARGEAAPGTIVEAAPEGVVVACGSGALRVTQLQKPG
CCCCCCEEEECCCEEEEEECCCCCCCCCCCCCCEEECCCCCEEEEECCCCEEEEEECCCC
GKRLPAREFLAGSPLAAGQRFALTDVA
CCCCCHHHHHCCCCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA