Click here to switch to the map view.

The map label for this gene is htpX [H]

Identifier: 78067944

GI number: 78067944

Start: 3643494

End: 3644351

Strand: Reverse

Name: htpX [H]

Synonym: Bcep18194_A6475

Alternate gene names: 78067944

Gene position: 3644351-3643494 (Counterclockwise)

Preceding gene: 78067945

Following gene: 78067943

Centisome position: 98.65

GC content: 65.62

Gene sequence:

>858_bases
ATGTTCAATTGGGTCAAAACGGCGATGCTGATGGCCGCGATCACGGCCCTGTTCATCGTGATCGGCGGGATGATCGGCGG
CTCGCGGGGCATGACGATCGCGCTGCTGTTCGCGCTCGGCATGAATTTCTTCTCTTACTGGTTCTCGGACAAGATGGTGC
TGCGCATGTACAACGCGCAGGAAGTCGACGAGAACACGGCGCCGCAGTTCTACCGGATGGTGCGCGAGCTGGCTACGCGC
GCGAACTTGCCGATGCCGCGCGTCTACCTGATCAACGAGGATGCGCCGAACGCATTTGCGACCGGCCGCAACCCGGAGCA
CGCGGCAGTCGCCGCGACGACGGGCATCCTGCGCGTGCTGTCGGAGCGCGAGATGCGCGGCGTGATGGCGCACGAGCTCG
CACACGTGAAGCACCGCGACATCCTGATCTCGACGATCACCGCGACGATGGCAGGCGCGATCTCGGCAATCGCGAACTTC
GCGATGTTCTTCGGCGGGCGCGACGAGAATGGCCGGCCGGCCAACCCGATCGCGGGTATCGCGGTCGCGCTGCTCGCGCC
GATCGCCGGCGCGCTGATCCAGATGGCGATTTCGCGGGCTCGCGAGTTCGAGGCCGATCGCGGTGGCGCGCAGATCTCCG
GCGATCCGCAGTCGCTTGCGACTGCGCTCGACAAGATCCATCGCTATGCGGCGGGCATCCCGTTCCAGGCAGCCGAGCAG
CATCCGGCCACCGCGCAGATGATGATCATGAATCCGCTGCACGGCGGCGGCCTGCAGAATCTGTTCTCGACGCACCCGGC
CACCGAGGAACGGATCGCGCGCCTGATGGAGATGGCGCGTACCGGTCGCTTCGACTAA

Upstream 100 bases:

>100_bases
GATTGAATTTTTCCGGCAAGACCTTATCTAACAAATCGCTTACAATTTTCCGCCGCGCCCTTTGATGCGCGGCGGGCCCC
CTGACGGATAAGGAGTGGGT

Downstream 100 bases:

>100_bases
GCCAAAGCTACGGCACACCGTGCGGCAGTTGCCGCGCGGGAGCCGCCATGCCACCCCGCACGCTTTGCGCTGCGGGGTGT
TTCATTTGTGCGCGCCGTAA

Product: M48 family peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MFNWVKTAMLMAAITALFIVIGGMIGGSRGMTIALLFALGMNFFSYWFSDKMVLRMYNAQEVDENTAPQFYRMVRELATR
ANLPMPRVYLINEDAPNAFATGRNPEHAAVAATTGILRVLSEREMRGVMAHELAHVKHRDILISTITATMAGAISAIANF
AMFFGGRDENGRPANPIAGIAVALLAPIAGALIQMAISRAREFEADRGGAQISGDPQSLATALDKIHRYAAGIPFQAAEQ
HPATAQMMIMNPLHGGGLQNLFSTHPATEERIARLMEMARTGRFD

Sequences:

>Translated_285_residues
MFNWVKTAMLMAAITALFIVIGGMIGGSRGMTIALLFALGMNFFSYWFSDKMVLRMYNAQEVDENTAPQFYRMVRELATR
ANLPMPRVYLINEDAPNAFATGRNPEHAAVAATTGILRVLSEREMRGVMAHELAHVKHRDILISTITATMAGAISAIANF
AMFFGGRDENGRPANPIAGIAVALLAPIAGALIQMAISRAREFEADRGGAQISGDPQSLATALDKIHRYAAGIPFQAAEQ
HPATAQMMIMNPLHGGGLQNLFSTHPATEERIARLMEMARTGRFD
>Mature_285_residues
MFNWVKTAMLMAAITALFIVIGGMIGGSRGMTIALLFALGMNFFSYWFSDKMVLRMYNAQEVDENTAPQFYRMVRELATR
ANLPMPRVYLINEDAPNAFATGRNPEHAAVAATTGILRVLSEREMRGVMAHELAHVKHRDILISTITATMAGAISAIANF
AMFFGGRDENGRPANPIAGIAVALLAPIAGALIQMAISRAREFEADRGGAQISGDPQSLATALDKIHRYAAGIPFQAAEQ
HPATAQMMIMNPLHGGGLQNLFSTHPATEERIARLMEMARTGRFD

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=269, Percent_Identity=32.7137546468402, Blast_Score=102, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 31011; Mature: 31011

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
7.0 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
7.0 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNWVKTAMLMAAITALFIVIGGMIGGSRGMTIALLFALGMNFFSYWFSDKMVLRMYNAQ
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHCHH
EVDENTAPQFYRMVRELATRANLPMPRVYLINEDAPNAFATGRNPEHAAVAATTGILRVL
HCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHH
SEREMRGVMAHELAHVKHRDILISTITATMAGAISAIANFAMFFGGRDENGRPANPIAGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
AVALLAPIAGALIQMAISRAREFEADRGGAQISGDPQSLATALDKIHRYAAGIPFQAAEQ
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
HPATAQMMIMNPLHGGGLQNLFSTHPATEERIARLMEMARTGRFD
CCCCCCEEEECCCCCCCHHHHHHCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MFNWVKTAMLMAAITALFIVIGGMIGGSRGMTIALLFALGMNFFSYWFSDKMVLRMYNAQ
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHCHH
EVDENTAPQFYRMVRELATRANLPMPRVYLINEDAPNAFATGRNPEHAAVAATTGILRVL
HCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHH
SEREMRGVMAHELAHVKHRDILISTITATMAGAISAIANFAMFFGGRDENGRPANPIAGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
AVALLAPIAGALIQMAISRAREFEADRGGAQISGDPQSLATALDKIHRYAAGIPFQAAEQ
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
HPATAQMMIMNPLHGGGLQNLFSTHPATEERIARLMEMARTGRFD
CCCCCCEEEECCCCCCCHHHHHHCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA