Click here to switch to the map view.

The map label for this gene is lsrR [H]

Identifier: 78067387

GI number: 78067387

Start: 3041303

End: 3042316

Strand: Direct

Name: lsrR [H]

Synonym: Bcep18194_A5918

Alternate gene names: 78067387

Gene position: 3041303-3042316 (Clockwise)

Preceding gene: 78067386

Following gene: 78067390

Centisome position: 82.33

GC content: 69.72

Gene sequence:

>1014_bases
ATGCGGCCCGCCGGCCGGCCCGCGGGGCGGCCCCCAGATCCGAATCGAATCGCTATCGTGTCCAAGTCCTCAGAAAAACT
CGATCTCGCCACGCGTGCCGCGTGGCTCTACTACGTCGCGGGCGACACGCAGAACGAAATCGCGGAAAAGCTGCAGGTGT
CGCGCCCGGTCGCGCAGCGCCTCGTCGCGTTCGCGGTCGAGAAGAACCTGATCCGCGTGCGCGTCGACCACCAGCTCGCC
GACTGTCTCGATCTCGGCGCGCAGCTCTCGAAACGCTACGGCCTCGCGATGTGCGAAGTCGTACCCGTCGATGCCGACGC
GCCCGACGCGATCGACCGCAAGCTCGCGGTCGCCGGCGCGCAGGTGATGGAGCGCTACCTGAACGAAACGCGGCCGATGG
TGATCGCGGTCAGCAGCGGCCGGACGCTGAAGGCCGCGGTCGCGCAGATCGCGCAGATCGACCGGCCGCAGCACCGGCTC
GTGTCGATGGTCGGCGCGATCGCCGCCGACGGTTCGTCGAACCGCTACGACGTCGCGCAGTACATCTCCGAAAAAACCGG
CAGCAAGCACTTCCTGCTGCCCGCGCCGCTGTTCGCCGACAGCGATGCCGAGCGCGCGCAGTGGTGCAATCACCGGCTGT
ACCGGATCGTCGAGGCGCTGTCGGGCAAGGCCGACGTCGCGTTCGTCGGGATCGGCAACATCGGCCCGCACTGCCCGCTC
TACGAAGACGGCTTCATCACCGAACAGGAGCGCGACGAGATGACCGCGCTCGGCGCGGTGGCCGAACTGCTCGGCGTGCC
GATCGACGCGCAGGGTACGCAGATCGCCGTGTCGACGAGCGCGCGCGTGACGAGCGTGTCGCTCGCCACGCCGCCGAAGC
GCCCGACGATCGCGTTCGCCGGCGGCCCGAAGAAGCGCGATGCGGTGATCGCCGCGCTGCGTGGCGGCTGGCTGTCGGGC
CTCGTCACCGACGAAACCTGCGCGCGCGCCGCGCTCGACGCGAAGGCGGCCTGA

Upstream 100 bases:

>100_bases
CGCTGTACGAACCGTCGCGCGCGCGGCTCGCGTAAGCGCCGCACGTCACGCGTGGCGGCCGCCGGCCGCGCGCGCGACAT
GCGGTACAGTGGATGCCGTC

Downstream 100 bases:

>100_bases
CGCCGAAGCCGCGCACCGCGCGCGGCAGTCGAACGCTCAAGCCGCGTGCGGTGCCGGAAACGCATGCCAGCGCGCACGCC
ACGCGCCGACCCAGGCCGCC

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MRPAGRPAGRPPDPNRIAIVSKSSEKLDLATRAAWLYYVAGDTQNEIAEKLQVSRPVAQRLVAFAVEKNLIRVRVDHQLA
DCLDLGAQLSKRYGLAMCEVVPVDADAPDAIDRKLAVAGAQVMERYLNETRPMVIAVSSGRTLKAAVAQIAQIDRPQHRL
VSMVGAIAADGSSNRYDVAQYISEKTGSKHFLLPAPLFADSDAERAQWCNHRLYRIVEALSGKADVAFVGIGNIGPHCPL
YEDGFITEQERDEMTALGAVAELLGVPIDAQGTQIAVSTSARVTSVSLATPPKRPTIAFAGGPKKRDAVIAALRGGWLSG
LVTDETCARAALDAKAA

Sequences:

>Translated_337_residues
MRPAGRPAGRPPDPNRIAIVSKSSEKLDLATRAAWLYYVAGDTQNEIAEKLQVSRPVAQRLVAFAVEKNLIRVRVDHQLA
DCLDLGAQLSKRYGLAMCEVVPVDADAPDAIDRKLAVAGAQVMERYLNETRPMVIAVSSGRTLKAAVAQIAQIDRPQHRL
VSMVGAIAADGSSNRYDVAQYISEKTGSKHFLLPAPLFADSDAERAQWCNHRLYRIVEALSGKADVAFVGIGNIGPHCPL
YEDGFITEQERDEMTALGAVAELLGVPIDAQGTQIAVSTSARVTSVSLATPPKRPTIAFAGGPKKRDAVIAALRGGWLSG
LVTDETCARAALDAKAA
>Mature_337_residues
MRPAGRPAGRPPDPNRIAIVSKSSEKLDLATRAAWLYYVAGDTQNEIAEKLQVSRPVAQRLVAFAVEKNLIRVRVDHQLA
DCLDLGAQLSKRYGLAMCEVVPVDADAPDAIDRKLAVAGAQVMERYLNETRPMVIAVSSGRTLKAAVAQIAQIDRPQHRL
VSMVGAIAADGSSNRYDVAQYISEKTGSKHFLLPAPLFADSDAERAQWCNHRLYRIVEALSGKADVAFVGIGNIGPHCPL
YEDGFITEQERDEMTALGAVAELLGVPIDAQGTQIAVSTSARVTSVSLATPPKRPTIAFAGGPKKRDAVIAALRGGWLSG
LVTDETCARAALDAKAA

Specific function: Regulates transcription of many different genes. In the absence of autoinducer 2 (AI-2), represses transcription of the lsrACDBFG operon and its own transcription. In the presence of AI- 2, lsrR is inactivated by binding phospho-AI-2, leading to the trans

COG id: COG2390

COG function: function code K; Transcriptional regulator, contains sigma factor-related N-terminal domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sorC transcriptional regulatory family [H]

Homologues:

Organism=Escherichia coli, GI1787791, Length=307, Percent_Identity=29.3159609120521, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI87082414, Length=313, Percent_Identity=24.9201277955272, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04198 Sugar-bind [H]

EC number: NA

Molecular weight: Translated: 36059; Mature: 36059

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPAGRPAGRPPDPNRIAIVSKSSEKLDLATRAAWLYYVAGDTQNEIAEKLQVSRPVAQR
CCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHEEEEEEEECCCHHHHHHHHHHHHHHHHH
LVAFAVEKNLIRVRVDHQLADCLDLGAQLSKRYGLAMCEVVPVDADAPDAIDRKLAVAGA
HHHHHHHCCEEEEEECHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHH
QVMERYLNETRPMVIAVSSGRTLKAAVAQIAQIDRPQHRLVSMVGAIAADGSSNRYDVAQ
HHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHH
YISEKTGSKHFLLPAPLFADSDAERAQWCNHRLYRIVEALSGKADVAFVGIGNIGPHCPL
HHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCC
YEDGFITEQERDEMTALGAVAELLGVPIDAQGTQIAVSTSARVTSVSLATPPKRPTIAFA
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCEEEEEEECCCCCCCEEEEC
GGPKKRDAVIAALRGGWLSGLVTDETCARAALDAKAA
CCCCCHHHHHHHHHCCHHHCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MRPAGRPAGRPPDPNRIAIVSKSSEKLDLATRAAWLYYVAGDTQNEIAEKLQVSRPVAQR
CCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHEEEEEEEECCCHHHHHHHHHHHHHHHHH
LVAFAVEKNLIRVRVDHQLADCLDLGAQLSKRYGLAMCEVVPVDADAPDAIDRKLAVAGA
HHHHHHHCCEEEEEECHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHH
QVMERYLNETRPMVIAVSSGRTLKAAVAQIAQIDRPQHRLVSMVGAIAADGSSNRYDVAQ
HHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHH
YISEKTGSKHFLLPAPLFADSDAERAQWCNHRLYRIVEALSGKADVAFVGIGNIGPHCPL
HHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCC
YEDGFITEQERDEMTALGAVAELLGVPIDAQGTQIAVSTSARVTSVSLATPPKRPTIAFA
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCEEEEEEECCCCCCCEEEEC
GGPKKRDAVIAALRGGWLSGLVTDETCARAALDAKAA
CCCCCHHHHHHHHHCCHHHCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA