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The map label for this gene is xylB [H]

Identifier: 78067386

GI number: 78067386

Start: 3039756

End: 3041237

Strand: Direct

Name: xylB [H]

Synonym: Bcep18194_A5917

Alternate gene names: 78067386

Gene position: 3039756-3041237 (Clockwise)

Preceding gene: 78067385

Following gene: 78067387

Centisome position: 82.29

GC content: 71.79

Gene sequence:

>1482_bases
ATGTATCTCGGCATCGACCTCGGCACCTCGGAAGTGAAGGTGCTGCTGCTCGCCCCGGACGGCACGGTCGTCGGCACCGC
CGGCTCGCCGTTCAGCGTGTCGCGGCCGCACCCGCGCTGGGCCGAGCAGCATCCGGACGACTGGTGGCAAGGCACGCTCG
CCGCGCTCGCGACCCTGCGCGAGCGGCACCGCGAGGCGTTCGCGGCCGTGCGCGGCATCGGCCTGTCGGGCCAGATGCAC
GGCGCCGTGCTGCTCGGGCGCGACGATCGCGTGCTGCGCCCCGCGATCCTGTGGAACGACATGCGCAGCGCCGACGAATG
TGCGCTGCTCACCGACCGCGCGCCCGATCTCCACGCACTGGCCGGCAATCTCGCGATGCCGGGCTTCACCGCGCCGAAAC
TGCTGTGGGTCGCGAAGCACGAGCCCGACGTGTTCGCGGCGACCGCGTGCGTGTTGATGCCGAAGGATTACCTGCGGTTC
CGGCTGACCGGCGCGAAGGTGTCCGATCCGTCGGACGCGGCCGGCACGCTGTGGCTCGACGTCGCACGCCGCGACTGGTC
CGACGCGCTGCTCGCCGCATGCGGAATGACACGTGACCAGATGCCGCGCATCGTCGAAGGCAATGCGCCGTCCGGCACGC
TGCGCGCGGACATCGCACGCGAACTCGGGCTGTCGGAAGCCGTCGTGGTGGCCGGCGGCGGCGGCGACAACGCGACGAGC
GCGCTCGGCATCGGCGCGATCCATGCAGGCGACGGCTTCGTATCGCTCGGCACGTCCGGCGTGCTGAGCGTGGTCGGCGA
TCGCTTCATGCCGAACCCTTCATCGGCCGTGCATGCGTTCTGCCACGCGATTCCCGATCGCTGGCAATTGATGAGCGTCG
TGCTGTCGGCCGCGAGCTGCCTGCGCTGGGTCTGCAAGCTGACCGGTACCGACGAGCCCGCGCTGCTCGCCGAAGTCGAG
GCGCTCGACGCCGACGCGCTCGCGACGGCGCCGCTGTTCCTGCCCTACCTGTCCGGCGAGCGCACGCCGCACAACGATCC
GTACGCGCAGGGCGTGTTCTTCGGAATGACGCATGCGACCGAACGCGCACACCTCGGCTACGCGGTGCTCGAAGGCGTGA
CGCTCGGCCTCGCCGACGGTCTCGACGCGCTGCATGCGGCCGGTGTCGAAACCGATCAGCTGTCGCTGATCGGCGGCGGC
GCGCGCAGCGCGTTCTGGGCGCAACTGATCGCCGATGCGCTGAACGTGCGCACGCGCCAGCACGGCGGCGGCGAAACGGG
CGCGGCGCTCGGCGCGGCCCGGCTTGGCTGGCTGGCCGTCGGCGGCGATCCGCATGCGGTGCTGACCAAGCCGCCGGTGC
GCGCCGAGTACGCGCCGGATGCCGCCCGCCATGCGCTGCTGCGCGAACGCCTCGACGCGTTCCGCGCGCTGTACCGTCAC
GTGCAGCCGCTGTACGAACCGTCGCGCGCGCGGCTCGCGTAA

Upstream 100 bases:

>100_bases
GGCTCGCGGCACGCTGACGCGCATCCGGGCGAACCTGCCTTGGCACGGGCGCGGCCGCGCGGCTAAAGTAGCGACTCCCC
ACTGACGGAACGGATCGCTC

Downstream 100 bases:

>100_bases
GCGCCGCACGTCACGCGTGGCGGCCGCCGGCCGCGCGCGCGACATGCGGTACAGTGGATGCCGTCATGCGGCCCGCCGGC
CGGCCCGCGGGGCGGCCCCC

Product: xylulokinase

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 493; Mature: 493

Protein sequence:

>493_residues
MYLGIDLGTSEVKVLLLAPDGTVVGTAGSPFSVSRPHPRWAEQHPDDWWQGTLAALATLRERHREAFAAVRGIGLSGQMH
GAVLLGRDDRVLRPAILWNDMRSADECALLTDRAPDLHALAGNLAMPGFTAPKLLWVAKHEPDVFAATACVLMPKDYLRF
RLTGAKVSDPSDAAGTLWLDVARRDWSDALLAACGMTRDQMPRIVEGNAPSGTLRADIARELGLSEAVVVAGGGGDNATS
ALGIGAIHAGDGFVSLGTSGVLSVVGDRFMPNPSSAVHAFCHAIPDRWQLMSVVLSAASCLRWVCKLTGTDEPALLAEVE
ALDADALATAPLFLPYLSGERTPHNDPYAQGVFFGMTHATERAHLGYAVLEGVTLGLADGLDALHAAGVETDQLSLIGGG
ARSAFWAQLIADALNVRTRQHGGGETGAALGAARLGWLAVGGDPHAVLTKPPVRAEYAPDAARHALLRERLDAFRALYRH
VQPLYEPSRARLA

Sequences:

>Translated_493_residues
MYLGIDLGTSEVKVLLLAPDGTVVGTAGSPFSVSRPHPRWAEQHPDDWWQGTLAALATLRERHREAFAAVRGIGLSGQMH
GAVLLGRDDRVLRPAILWNDMRSADECALLTDRAPDLHALAGNLAMPGFTAPKLLWVAKHEPDVFAATACVLMPKDYLRF
RLTGAKVSDPSDAAGTLWLDVARRDWSDALLAACGMTRDQMPRIVEGNAPSGTLRADIARELGLSEAVVVAGGGGDNATS
ALGIGAIHAGDGFVSLGTSGVLSVVGDRFMPNPSSAVHAFCHAIPDRWQLMSVVLSAASCLRWVCKLTGTDEPALLAEVE
ALDADALATAPLFLPYLSGERTPHNDPYAQGVFFGMTHATERAHLGYAVLEGVTLGLADGLDALHAAGVETDQLSLIGGG
ARSAFWAQLIADALNVRTRQHGGGETGAALGAARLGWLAVGGDPHAVLTKPPVRAEYAPDAARHALLRERLDAFRALYRH
VQPLYEPSRARLA
>Mature_493_residues
MYLGIDLGTSEVKVLLLAPDGTVVGTAGSPFSVSRPHPRWAEQHPDDWWQGTLAALATLRERHREAFAAVRGIGLSGQMH
GAVLLGRDDRVLRPAILWNDMRSADECALLTDRAPDLHALAGNLAMPGFTAPKLLWVAKHEPDVFAATACVLMPKDYLRF
RLTGAKVSDPSDAAGTLWLDVARRDWSDALLAACGMTRDQMPRIVEGNAPSGTLRADIARELGLSEAVVVAGGGGDNATS
ALGIGAIHAGDGFVSLGTSGVLSVVGDRFMPNPSSAVHAFCHAIPDRWQLMSVVLSAASCLRWVCKLTGTDEPALLAEVE
ALDADALATAPLFLPYLSGERTPHNDPYAQGVFFGMTHATERAHLGYAVLEGVTLGLADGLDALHAAGVETDQLSLIGGG
ARSAFWAQLIADALNVRTRQHGGGETGAALGAARLGWLAVGGDPHAVLTKPPVRAEYAPDAARHALLRERLDAFRALYRH
VQPLYEPSRARLA

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI42794763, Length=438, Percent_Identity=22.3744292237443, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI189409120, Length=438, Percent_Identity=22.6027397260274, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI4504007, Length=438, Percent_Identity=22.6027397260274, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI41393575, Length=405, Percent_Identity=22.2222222222222, Blast_Score=91, Evalue=3e-18,
Organism=Escherichia coli, GI1789987, Length=487, Percent_Identity=52.3613963039014, Blast_Score=481, Evalue=1e-137,
Organism=Escherichia coli, GI1790005, Length=499, Percent_Identity=26.6533066132265, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1789168, Length=496, Percent_Identity=26.4112903225806, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1790361, Length=478, Percent_Identity=23.2217573221757, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1787789, Length=373, Percent_Identity=25.201072386059, Blast_Score=98, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17535599, Length=453, Percent_Identity=23.6203090507726, Blast_Score=93, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6321633, Length=336, Percent_Identity=25.5952380952381, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24657106, Length=467, Percent_Identity=22.9122055674518, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24657102, Length=467, Percent_Identity=22.9122055674518, Blast_Score=77, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 52220; Mature: 52220

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS00933 FGGY_KINASES_1 ; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLGIDLGTSEVKVLLLAPDGTVVGTAGSPFSVSRPHPRWAEQHPDDWWQGTLAALATLR
CEEEEECCCCCEEEEEECCCCCEEECCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHH
ERHREAFAAVRGIGLSGQMHGAVLLGRDDRVLRPAILWNDMRSADECALLTDRAPDLHAL
HHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCHHHHHHCCCCCCCEEEECCCCCCHHHH
AGNLAMPGFTAPKLLWVAKHEPDVFAATACVLMPKDYLRFRLTGAKVSDPSDAAGTLWLD
HCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCHHEEEEEECCCCCCCCCCCCEEEEE
VARRDWSDALLAACGMTRDQMPRIVEGNAPSGTLRADIARELGLSEAVVVAGGGGDNATS
EHHCCHHHHHHHHHCCCHHHCCCEEECCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCH
ALGIGAIHAGDGFVSLGTSGVLSVVGDRFMPNPSSAVHAFCHAIPDRWQLMSVVLSAASC
HHEEEEEECCCCEEECCCCHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHH
LRWVCKLTGTDEPALLAEVEALDADALATAPLFLPYLSGERTPHNDPYAQGVFFGMTHAT
HHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHH
ERAHLGYAVLEGVTLGLADGLDALHAAGVETDQLSLIGGGARSAFWAQLIADALNVRTRQ
HHHHCCHHHHHHHHHHHHCCHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHC
HGGGETGAALGAARLGWLAVGGDPHAVLTKPPVRAEYAPDAARHALLRERLDAFRALYRH
CCCCCCHHHHHHHHHCEEEECCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VQPLYEPSRARLA
HHHHCCCCCCCCC
>Mature Secondary Structure
MYLGIDLGTSEVKVLLLAPDGTVVGTAGSPFSVSRPHPRWAEQHPDDWWQGTLAALATLR
CEEEEECCCCCEEEEEECCCCCEEECCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHH
ERHREAFAAVRGIGLSGQMHGAVLLGRDDRVLRPAILWNDMRSADECALLTDRAPDLHAL
HHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCHHHHHHCCCCCCCEEEECCCCCCHHHH
AGNLAMPGFTAPKLLWVAKHEPDVFAATACVLMPKDYLRFRLTGAKVSDPSDAAGTLWLD
HCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCHHEEEEEECCCCCCCCCCCCEEEEE
VARRDWSDALLAACGMTRDQMPRIVEGNAPSGTLRADIARELGLSEAVVVAGGGGDNATS
EHHCCHHHHHHHHHCCCHHHCCCEEECCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCH
ALGIGAIHAGDGFVSLGTSGVLSVVGDRFMPNPSSAVHAFCHAIPDRWQLMSVVLSAASC
HHEEEEEECCCCEEECCCCHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHH
LRWVCKLTGTDEPALLAEVEALDADALATAPLFLPYLSGERTPHNDPYAQGVFFGMTHAT
HHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHH
ERAHLGYAVLEGVTLGLADGLDALHAAGVETDQLSLIGGGARSAFWAQLIADALNVRTRQ
HHHHCCHHHHHHHHHHHHCCHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHC
HGGGETGAALGAARLGWLAVGGDPHAVLTKPPVRAEYAPDAARHALLRERLDAFRALYRH
CCCCCCHHHHHHHHHCEEEECCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VQPLYEPSRARLA
HHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6320721; 8041620; 9278503 [H]