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The map label for this gene is xerD

Identifier: 78067360

GI number: 78067360

Start: 3011564

End: 3012514

Strand: Reverse

Name: xerD

Synonym: Bcep18194_A5891

Alternate gene names: 78067360

Gene position: 3012514-3011564 (Counterclockwise)

Preceding gene: 78067361

Following gene: 78067358

Centisome position: 81.55

GC content: 68.98

Gene sequence:

>951_bases
ATGAGTGAATCGCTGATTTCTCCCGAAGCCGACGGCGATGCCGCCGCGGCGTCACCCGCGCTGCTCGCGAGCCGTGCGTC
GATCGACGTGTTTTGCGATGCGCTGTGGCTCGAGCACGGGCTCGCGCGCAACACGCTCGACGCATACCGGCGCGATCTGG
TGCTGTTTTCCCAATGGCTGGCGGAGACGCACGACGCGCCGCTCGATTCGGTCGACGAAGCGATGGTGACGGGCTACATC
GCCGCGCGCAGCGACGGCAAGGCGACGTCGTCGAACCGGCGGCTGTCCGTGTTCCGGCGCTATTACGGCTGGGCCGTGCG
CGAGCATCGTGTGAGCGCCGACCCGACGCTGCGGATCACGTCCGCGAAACAGGCCGCCCGGTTTCCGTCGACGCTGTCGG
AGGCGCAGGTCGAGGCGCTGCTCGGCGCGCCCGACATCGGCACGCCGCTCGGCCTGCGCGATCGCACGATGCTCGAGCTG
ATGTATGCGAGCGGGTTGCGCGTGAGCGAGCTCGTGATGCTGAAGACCGTCGAGGTCGGGCTCAACGAGGGCGTCGTGCG
CGTGATGGGCAAGGGGTCGAAAGAGCGGCTCGTGCCGTTCGGCGAAGTCGCGCACGGCTGGATCGAGCGCTACCTGCGCG
ACGCGCGGCCGGCGCTGCTCGGCGCGCGCGCGGCCGACGCGCTGTTCGTGACCGCGCGCGGCGACGGGATGACGCGCCAG
CAGTTCTGGAACATCATCAAGCGCCACGCGCAGCACGCGGAAGTGCGCGCGCACCTGTCGCCGCATACGCTGCGGCACGC
GTTCGCGACGCACCTGCTGAATCATGGCGCCGACCTGCGCGTCGTGCAGTTGCTGCTCGGCCACAGCGACATCTCGACCA
CGCAGATCTATACGCACGTTGCACGCGAGCGCTTGAAGACGCTGCACGCGCAACACCATCCGCGCGGTTAG

Upstream 100 bases:

>100_bases
TCGCGGCGGGCGGCCTCGGCGGCTTCGCGAACCACGACGACAACGGTTATTACCAGAAAGTGAAGCGCTGGCTGCTGGCG
CACGAAGGCGTGCCGTACTG

Downstream 100 bases:

>100_bases
CGCATCCAGCGTGGCGCGCGCTGTGTCACGCGCCGAGCCGGCCCAGGTCAGACCAGTTCGCGCAGCTTGTGCTTCAGCAC
CTTGCCCGTCGACGCGGCCG

Product: site-specific tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MSESLISPEADGDAAAASPALLASRASIDVFCDALWLEHGLARNTLDAYRRDLVLFSQWLAETHDAPLDSVDEAMVTGYI
AARSDGKATSSNRRLSVFRRYYGWAVREHRVSADPTLRITSAKQAARFPSTLSEAQVEALLGAPDIGTPLGLRDRTMLEL
MYASGLRVSELVMLKTVEVGLNEGVVRVMGKGSKERLVPFGEVAHGWIERYLRDARPALLGARAADALFVTARGDGMTRQ
QFWNIIKRHAQHAEVRAHLSPHTLRHAFATHLLNHGADLRVVQLLLGHSDISTTQIYTHVARERLKTLHAQHHPRG

Sequences:

>Translated_316_residues
MSESLISPEADGDAAAASPALLASRASIDVFCDALWLEHGLARNTLDAYRRDLVLFSQWLAETHDAPLDSVDEAMVTGYI
AARSDGKATSSNRRLSVFRRYYGWAVREHRVSADPTLRITSAKQAARFPSTLSEAQVEALLGAPDIGTPLGLRDRTMLEL
MYASGLRVSELVMLKTVEVGLNEGVVRVMGKGSKERLVPFGEVAHGWIERYLRDARPALLGARAADALFVTARGDGMTRQ
QFWNIIKRHAQHAEVRAHLSPHTLRHAFATHLLNHGADLRVVQLLLGHSDISTTQIYTHVARERLKTLHAQHHPRG
>Mature_315_residues
SESLISPEADGDAAAASPALLASRASIDVFCDALWLEHGLARNTLDAYRRDLVLFSQWLAETHDAPLDSVDEAMVTGYIA
ARSDGKATSSNRRLSVFRRYYGWAVREHRVSADPTLRITSAKQAARFPSTLSEAQVEALLGAPDIGTPLGLRDRTMLELM
YASGLRVSELVMLKTVEVGLNEGVVRVMGKGSKERLVPFGEVAHGWIERYLRDARPALLGARAADALFVTARGDGMTRQQ
FWNIIKRHAQHAEVRAHLSPHTLRHAFATHLLNHGADLRVVQLLLGHSDISTTQIYTHVARERLKTLHAQHHPRG

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=294, Percent_Identity=56.1224489795918, Blast_Score=302, Evalue=2e-83,
Organism=Escherichia coli, GI1790244, Length=294, Percent_Identity=38.7755102040816, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1790768, Length=168, Percent_Identity=33.9285714285714, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790767, Length=172, Percent_Identity=27.906976744186, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 34927; Mature: 34796

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSESLISPEADGDAAAASPALLASRASIDVFCDALWLEHGLARNTLDAYRRDLVLFSQWL
CCCCCCCCCCCCCHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AETHDAPLDSVDEAMVTGYIAARSDGKATSSNRRLSVFRRYYGWAVREHRVSADPTLRIT
HHHCCCCCCHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEE
SAKQAARFPSTLSEAQVEALLGAPDIGTPLGLRDRTMLELMYASGLRVSELVMLKTVEVG
CHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHC
LNEGVVRVMGKGSKERLVPFGEVAHGWIERYLRDARPALLGARAADALFVTARGDGMTRQ
CCCCHHEECCCCCHHHCCCHHHHHHHHHHHHHHHCCHHHHHCCCCCEEEEEECCCCCCHH
QFWNIIKRHAQHAEVRAHLSPHTLRHAFATHLLNHGADLRVVQLLLGHSDISTTQIYTHV
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHH
ARERLKTLHAQHHPRG
HHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SESLISPEADGDAAAASPALLASRASIDVFCDALWLEHGLARNTLDAYRRDLVLFSQWL
CCCCCCCCCCCCHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AETHDAPLDSVDEAMVTGYIAARSDGKATSSNRRLSVFRRYYGWAVREHRVSADPTLRIT
HHHCCCCCCHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEE
SAKQAARFPSTLSEAQVEALLGAPDIGTPLGLRDRTMLELMYASGLRVSELVMLKTVEVG
CHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHC
LNEGVVRVMGKGSKERLVPFGEVAHGWIERYLRDARPALLGARAADALFVTARGDGMTRQ
CCCCHHEECCCCCHHHCCCHHHHHHHHHHHHHHHCCHHHHHCCCCCEEEEEECCCCCCHH
QFWNIIKRHAQHAEVRAHLSPHTLRHAFATHLLNHGADLRVVQLLLGHSDISTTQIYTHV
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHH
ARERLKTLHAQHHPRG
HHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]