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The map label for this gene is gltC [H]

Identifier: 78066199

GI number: 78066199

Start: 1721238

End: 1722191

Strand: Direct

Name: gltC [H]

Synonym: Bcep18194_A4729

Alternate gene names: 78066199

Gene position: 1721238-1722191 (Clockwise)

Preceding gene: 78066196

Following gene: 78066200

Centisome position: 46.59

GC content: 71.17

Gene sequence:

>954_bases
ATGGCGGCTTTCCTGCATGGCCTGGCGTTGCGGTATTTCGTCGAAGTGGCGCGCACCGGCTCGATCAGCGACGCGTCCGC
GCGGCTGCATGTGGCCGTATCGGCGATCAGCCGCCAGATCGCCAAACTGGAGAGCGAGCTCGGCGCACCGCTGTTCGAGC
GCCGGCCGCGCGGGATGGCGCTGTCGGAGGCCGGCGAGCGGCTCCTGGCGTTCGCGCAGCGCAGCCTGCTGGAGGCCGAG
CACGTGATGAAGGACATCGGCGGGCTCGATGCGCTGCACGGCAGCCTGCTGAAGATCGCGTGCTCGGAAGGGTTCGCGAT
CGACTTCCTGCCCGGCACGCTCGCCAGCTTCAAGGCGCGTCATCCGGGCGTCGATTTCTCCGTGTGGGTGGTGTCGCCGG
CGGACGCGACGCGGCGCGTGCGCGACGGCGATGTCGACATCGCGTTGAGTTTCAGCCTCGCGCCGGAGAAGGGCGTGCGC
GTCGACCACACCGAGCGCGCGCCGATCTTCGCGCTGGTGCGGCACGACCATCCGCTCGCGACGCGCGAAGCGGTGTCGCT
CGCCGATGTCGCGCGTCACCCGCACGTGCTGCCCGAGGCCGGCACGACAGTGCGCCAGCTGATCGACATCGCGTGCGCGC
TCGACGGGCTGCTGCTCGAGCCCGAACTGACGAGCAACAACACGGCGGCGATGTACGGCTACGCGCGGCGCACGGGCGCG
GTGATGTTCACGGGGCTGCTGTCGGTGCGCGACCGCTGCGCCGCGGACGGCTTCGTCGTCGTGCCCGTGACGAACCCGCA
GCTGCGCGAGCGCAGCATCCAGGTGCAGACGATGGCGGGGCGCGATCTGCCGGCGTCGGTCCGCGCGTTCCGCGACCATC
TGATCGACGCGATGCAGACTGCATCGGCGCCGCCGGCAGCCGCGCGCGGCCCGAGACGCCGGCCCGTGAGATAA

Upstream 100 bases:

>100_bases
TTCTAGAAAGCCGTTTTTTTTGTCACAATGATCGAATTTCGAACCTTTCTTTGCCGAAAAGGCAAAGCAGCGCGGCCAGC
AGCCGGGCGGAGACAGAACG

Downstream 100 bases:

>100_bases
TCGTCAATCCGCCTTCCGTGCCCATGCGGCTTATCGAGCCGCATCGCCCCTGTTCGACGCCAAATTGAAGAACCTGATTG
TCACCCTCGATCGCGCCGGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MAAFLHGLALRYFVEVARTGSISDASARLHVAVSAISRQIAKLESELGAPLFERRPRGMALSEAGERLLAFAQRSLLEAE
HVMKDIGGLDALHGSLLKIACSEGFAIDFLPGTLASFKARHPGVDFSVWVVSPADATRRVRDGDVDIALSFSLAPEKGVR
VDHTERAPIFALVRHDHPLATREAVSLADVARHPHVLPEAGTTVRQLIDIACALDGLLLEPELTSNNTAAMYGYARRTGA
VMFTGLLSVRDRCAADGFVVVPVTNPQLRERSIQVQTMAGRDLPASVRAFRDHLIDAMQTASAPPAAARGPRRRPVR

Sequences:

>Translated_317_residues
MAAFLHGLALRYFVEVARTGSISDASARLHVAVSAISRQIAKLESELGAPLFERRPRGMALSEAGERLLAFAQRSLLEAE
HVMKDIGGLDALHGSLLKIACSEGFAIDFLPGTLASFKARHPGVDFSVWVVSPADATRRVRDGDVDIALSFSLAPEKGVR
VDHTERAPIFALVRHDHPLATREAVSLADVARHPHVLPEAGTTVRQLIDIACALDGLLLEPELTSNNTAAMYGYARRTGA
VMFTGLLSVRDRCAADGFVVVPVTNPQLRERSIQVQTMAGRDLPASVRAFRDHLIDAMQTASAPPAAARGPRRRPVR
>Mature_316_residues
AAFLHGLALRYFVEVARTGSISDASARLHVAVSAISRQIAKLESELGAPLFERRPRGMALSEAGERLLAFAQRSLLEAEH
VMKDIGGLDALHGSLLKIACSEGFAIDFLPGTLASFKARHPGVDFSVWVVSPADATRRVRDGDVDIALSFSLAPEKGVRV
DHTERAPIFALVRHDHPLATREAVSLADVARHPHVLPEAGTTVRQLIDIACALDGLLLEPELTSNNTAAMYGYARRTGAV
MFTGLLSVRDRCAADGFVVVPVTNPQLRERSIQVQTMAGRDLPASVRAFRDHLIDAMQTASAPPAAARGPRRRPVR

Specific function: Positive regulator of glutamate biosynthesis (gltAB genes). Negatively regulates its own expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=272, Percent_Identity=29.7794117647059, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI145693105, Length=201, Percent_Identity=23.3830845771144, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788748, Length=214, Percent_Identity=27.1028037383178, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787879, Length=293, Percent_Identity=26.6211604095563, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1790208, Length=141, Percent_Identity=36.1702127659575, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788296, Length=235, Percent_Identity=29.3617021276596, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787530, Length=236, Percent_Identity=27.9661016949153, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1787601, Length=141, Percent_Identity=30.4964539007092, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87081904, Length=202, Percent_Identity=27.2277227722772, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788297, Length=217, Percent_Identity=27.1889400921659, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1788887, Length=186, Percent_Identity=29.0322580645161, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1789173, Length=195, Percent_Identity=32.3076923076923, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1789639, Length=131, Percent_Identity=32.0610687022901, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789204, Length=205, Percent_Identity=26.3414634146341, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787806, Length=119, Percent_Identity=34.453781512605, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790262, Length=182, Percent_Identity=24.7252747252747, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34228; Mature: 34097

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAFLHGLALRYFVEVARTGSISDASARLHVAVSAISRQIAKLESELGAPLFERRPRGMA
CHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCC
LSEAGERLLAFAQRSLLEAEHVMKDIGGLDALHGSLLKIACSEGFAIDFLPGTLASFKAR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHEEECCCCCEEEECCCHHHHHHCC
HPGVDFSVWVVSPADATRRVRDGDVDIALSFSLAPEKGVRVDHTERAPIFALVRHDHPLA
CCCCCEEEEEECCCCHHHHCCCCCEEEEEEEEECCCCCCCCCCCCCCCEEEEEECCCCCH
TREAVSLADVARHPHVLPEAGTTVRQLIDIACALDGLLLEPELTSNNTAAMYGYARRTGA
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCEEECCCCCCCCCEEEEHHHHHCCH
VMFTGLLSVRDRCAADGFVVVPVTNPQLRERSIQVQTMAGRDLPASVRAFRDHLIDAMQT
HHHHHHHHHHHHHCCCCEEEEECCCCHHHHHCEEEEEECCCCCCHHHHHHHHHHHHHHHH
ASAPPAAARGPRRRPVR
CCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AAFLHGLALRYFVEVARTGSISDASARLHVAVSAISRQIAKLESELGAPLFERRPRGMA
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCC
LSEAGERLLAFAQRSLLEAEHVMKDIGGLDALHGSLLKIACSEGFAIDFLPGTLASFKAR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHEEECCCCCEEEECCCHHHHHHCC
HPGVDFSVWVVSPADATRRVRDGDVDIALSFSLAPEKGVRVDHTERAPIFALVRHDHPLA
CCCCCEEEEEECCCCHHHHCCCCCEEEEEEEEECCCCCCCCCCCCCCCEEEEEECCCCCH
TREAVSLADVARHPHVLPEAGTTVRQLIDIACALDGLLLEPELTSNNTAAMYGYARRTGA
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCEEECCCCCCCCCEEEEHHHHHCCH
VMFTGLLSVRDRCAADGFVVVPVTNPQLRERSIQVQTMAGRDLPASVRAFRDHLIDAMQT
HHHHHHHHHHHHHCCCCEEEEECCCCHHHHHCEEEEEECCCCCCHHHHHHHHHHHHHHHH
ASAPPAAARGPRRRPVR
CCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2548995; 9384377 [H]