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The map label for this gene is tas [H]

Identifier: 78066196

GI number: 78066196

Start: 1717198

End: 1718250

Strand: Direct

Name: tas [H]

Synonym: Bcep18194_A4726

Alternate gene names: 78066196

Gene position: 1717198-1718250 (Clockwise)

Preceding gene: 78066195

Following gene: 78066199

Centisome position: 46.48

GC content: 65.91

Gene sequence:

>1053_bases
ATGGAATACCGCACACTTGGCGATTCAGGCATCGAGGTCAGCCTGATCGGCCTGGGCACGATGACGTGGGGCGAGCAGAA
TTCGGAGCGCGATGCGCACGAGCAGATCGACTACGCGATCGGGCAGGGCGTGACGCTGATCGATGCCGCGGAGATGTATC
CGGTGCCGCCGAAGCCCGATACGCAGGGGCGCACCGAGGAGTACATCGGCACCTGGCTCGCGCAGCATCGCGCGCAGCGC
GAGCGTATCGTGCTCGCGACGAAAATCGCGGGGCCGGCGCGGCAGCCGCACAATCCGCGCCATATTCGCGGCGAAGGCAA
CCAGTTCGACCGCAAGAACCTGACCGAAGCGCTCGACGGCAGCCTCAAGCGCCTGCAGACCGACTACGTCGATCTCTACC
AGTTGCACTGGCCCGATCGCAGCACGACGACGTTCGGCCGTCCCGCCTATCCGTGGGTCGACGATACCTATACGGTGCCG
ATCGAGGAAACCCTCGGCGTGCTCGCGGAATTCGTGAAGGCCGGCAAGGTGCGCGCGATCGGCGTGTCGAACGAAACGCC
GTGGGGCGTCGCGCAGTTCCTGCACGCGGCCGAGAAGCTCGGGCTGCCGCGTATCGCGAGCATCCAGAATCCGTACAGCC
TGCTGAACCGCACGTTCGAAAACGGCCTGTCGGAATTCTCGCATCGCGACGGCGTCGGTCTGCTCGCGTATTCGCCGCTT
GCGTTCGGCTGGCTGTCCGGCAAGTACGAGAACGGCGCGCGTCCGGCCGGCGCACGCATCACGTTGTTCGAACGCTTCCA
GCGTTACAGCAAGCCGCAGGCCGTCGAGGCGACGTCGCGCTATGTCGCGCTCGCACGGCGTCACGGGCTGTCGCCCGCGC
AGCTCGCGCTGGCGTTCGTCAACAGCCGGCCGTTCACGCACAGCAACCTGGTCGGGGCGACGTCGCTCGAGCAGTTGAAG
GAGAACATCGGCAGCATCGACGTGAAGCTGTCCGACGAGATCCTCGCCGAGATCGACGCGCTGCACGAACTGCAGCCGAA
CCCTGCGCCGTAA

Upstream 100 bases:

>100_bases
CCGGTGTCGAAGGCCGCCTGTAAGCGTATGCGGCGCGTGTCTGAAGCGGCCGCTTCAATGTGATAGCGTTCCTGCTTTCC
ACCGACGCGACAGGAACAGC

Downstream 100 bases:

>100_bases
ATGACGCGCGGCCCGCGCGGCAGCGATGCCGCGACGGGCCGCACCGGCGGCGCATCGCCGCGCCGTCGTTTCTTCCGTTA
TCGCATCTTGAGCCGTGTGC

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MEYRTLGDSGIEVSLIGLGTMTWGEQNSERDAHEQIDYAIGQGVTLIDAAEMYPVPPKPDTQGRTEEYIGTWLAQHRAQR
ERIVLATKIAGPARQPHNPRHIRGEGNQFDRKNLTEALDGSLKRLQTDYVDLYQLHWPDRSTTTFGRPAYPWVDDTYTVP
IEETLGVLAEFVKAGKVRAIGVSNETPWGVAQFLHAAEKLGLPRIASIQNPYSLLNRTFENGLSEFSHRDGVGLLAYSPL
AFGWLSGKYENGARPAGARITLFERFQRYSKPQAVEATSRYVALARRHGLSPAQLALAFVNSRPFTHSNLVGATSLEQLK
ENIGSIDVKLSDEILAEIDALHELQPNPAP

Sequences:

>Translated_350_residues
MEYRTLGDSGIEVSLIGLGTMTWGEQNSERDAHEQIDYAIGQGVTLIDAAEMYPVPPKPDTQGRTEEYIGTWLAQHRAQR
ERIVLATKIAGPARQPHNPRHIRGEGNQFDRKNLTEALDGSLKRLQTDYVDLYQLHWPDRSTTTFGRPAYPWVDDTYTVP
IEETLGVLAEFVKAGKVRAIGVSNETPWGVAQFLHAAEKLGLPRIASIQNPYSLLNRTFENGLSEFSHRDGVGLLAYSPL
AFGWLSGKYENGARPAGARITLFERFQRYSKPQAVEATSRYVALARRHGLSPAQLALAFVNSRPFTHSNLVGATSLEQLK
ENIGSIDVKLSDEILAEIDALHELQPNPAP
>Mature_350_residues
MEYRTLGDSGIEVSLIGLGTMTWGEQNSERDAHEQIDYAIGQGVTLIDAAEMYPVPPKPDTQGRTEEYIGTWLAQHRAQR
ERIVLATKIAGPARQPHNPRHIRGEGNQFDRKNLTEALDGSLKRLQTDYVDLYQLHWPDRSTTTFGRPAYPWVDDTYTVP
IEETLGVLAEFVKAGKVRAIGVSNETPWGVAQFLHAAEKLGLPRIASIQNPYSLLNRTFENGLSEFSHRDGVGLLAYSPL
AFGWLSGKYENGARPAGARITLFERFQRYSKPQAVEATSRYVALARRHGLSPAQLALAFVNSRPFTHSNLVGATSLEQLK
ENIGSIDVKLSDEILAEIDALHELQPNPAP

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=360, Percent_Identity=30.8333333333333, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI27436969, Length=360, Percent_Identity=31.3888888888889, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI27436962, Length=360, Percent_Identity=30.8333333333333, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI4504825, Length=356, Percent_Identity=30.8988764044944, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI27436966, Length=360, Percent_Identity=30.5555555555556, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI27436971, Length=362, Percent_Identity=30.3867403314917, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI41152114, Length=239, Percent_Identity=30.9623430962343, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI41327764, Length=329, Percent_Identity=27.0516717325228, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI223718702, Length=327, Percent_Identity=27.5229357798165, Blast_Score=76, Evalue=5e-14,
Organism=Escherichia coli, GI1789199, Length=350, Percent_Identity=58.5714285714286, Blast_Score=423, Evalue=1e-120,
Organism=Escherichia coli, GI87081735, Length=356, Percent_Identity=29.4943820224719, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1788070, Length=343, Percent_Identity=30.3206997084548, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1789375, Length=348, Percent_Identity=31.6091954022989, Blast_Score=118, Evalue=7e-28,
Organism=Escherichia coli, GI1788081, Length=359, Percent_Identity=27.2980501392758, Blast_Score=82, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6325169, Length=355, Percent_Identity=26.4788732394366, Blast_Score=101, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6323998, Length=352, Percent_Identity=27.5568181818182, Blast_Score=96, Evalue=7e-21,
Organism=Saccharomyces cerevisiae, GI6319958, Length=329, Percent_Identity=27.355623100304, Blast_Score=94, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6319951, Length=338, Percent_Identity=26.3313609467456, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6322615, Length=269, Percent_Identity=25.6505576208178, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324694, Length=248, Percent_Identity=30.6451612903226, Blast_Score=80, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6320576, Length=311, Percent_Identity=26.3665594855305, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320079, Length=235, Percent_Identity=29.7872340425532, Blast_Score=69, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24646159, Length=334, Percent_Identity=28.1437125748503, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24646155, Length=356, Percent_Identity=27.5280898876405, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 38884; Mature: 38884

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYRTLGDSGIEVSLIGLGTMTWGEQNSERDAHEQIDYAIGQGVTLIDAAEMYPVPPKPD
CCCCCCCCCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEHHHHCCCCCCCC
TQGRTEEYIGTWLAQHRAQRERIVLATKIAGPARQPHNPRHIRGEGNQFDRKNLTEALDG
CCCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCEECCCCCCCCHHHHHHHHHH
SLKRLQTDYVDLYQLHWPDRSTTTFGRPAYPWVDDTYTVPIEETLGVLAEFVKAGKVRAI
HHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHHCCCEEEE
GVSNETPWGVAQFLHAAEKLGLPRIASIQNPYSLLNRTFENGLSEFSHRDGVGLLAYSPL
ECCCCCCHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCH
AFGWLSGKYENGARPAGARITLFERFQRYSKPQAVEATSRYVALARRHGLSPAQLALAFV
HHHHHCCCCCCCCCCCCCEEHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHH
NSRPFTHSNLVGATSLEQLKENIGSIDVKLSDEILAEIDALHELQPNPAP
CCCCCCCCCCCCHHHHHHHHHHHCCEEEEECHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MEYRTLGDSGIEVSLIGLGTMTWGEQNSERDAHEQIDYAIGQGVTLIDAAEMYPVPPKPD
CCCCCCCCCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEHHHHCCCCCCCC
TQGRTEEYIGTWLAQHRAQRERIVLATKIAGPARQPHNPRHIRGEGNQFDRKNLTEALDG
CCCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCEECCCCCCCCHHHHHHHHHH
SLKRLQTDYVDLYQLHWPDRSTTTFGRPAYPWVDDTYTVPIEETLGVLAEFVKAGKVRAI
HHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHHCCCEEEE
GVSNETPWGVAQFLHAAEKLGLPRIASIQNPYSLLNRTFENGLSEFSHRDGVGLLAYSPL
ECCCCCCHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCH
AFGWLSGKYENGARPAGARITLFERFQRYSKPQAVEATSRYVALARRHGLSPAQLALAFV
HHHHHCCCCCCCCCCCCCEEHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHH
NSRPFTHSNLVGATSLEQLKENIGSIDVKLSDEILAEIDALHELQPNPAP
CCCCCCCCCCCCHHHHHHHHHHHCCEEEEECHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9560382; 9278503 [H]