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The map label for this gene is yycG [H]

Identifier: 78066053

GI number: 78066053

Start: 1557240

End: 1559627

Strand: Direct

Name: yycG [H]

Synonym: Bcep18194_A4582

Alternate gene names: 78066053

Gene position: 1557240-1559627 (Clockwise)

Preceding gene: 78066052

Following gene: 78066054

Centisome position: 42.15

GC content: 69.51

Gene sequence:

>2388_bases
ATGAAACCCGACTCCGTTTCTCCACGGCGGCGCCTCGGCCGCCGATTCCTGATCGAATGGATCGCGATCGGCTGCCTCGG
GGTCGCCGTGATCCTCGCGTGCGCGGTCGGCCGCATGTCGGCGAGCGTCGACGGCCTGATCTACGACCGGCTGCTGATGC
TGCGCAGTCTGCCGTTGTCACCCGACGTGGTCGTCGTCGACATCGACAACCAGAGCGTGTCCGCGCTCGGCCGCTGGCCG
TGGCCGCGCGACGTGCATGCGCGGCTGCTCGACACGCTGGCGCGCGCGCAACCGGCCGCCGTCGTCTACGACGTGCTGTT
TACCGAACCGTCGCCGGAAGATCGCGCGTTCGCGGACGCAATGACCCACGTGCCGACCTTCCTGCCCGTGCTGTTGAGTC
CCGAGCAGGCCGACGGCACGCGCGCGGTCGATCCGCCGGTGGCCGCGCTCGCGGCGCGCGCGGTCGGGCTCGGCCACATC
AACCTCGAAGTCGATCGCGACGGCATCGTCCGCAGCGTGGCGCTGTACGAAAGCGACGGCCGCGTGCGCTGGCCGCAGCT
GATGGTGCCCGTGTATCGCGCGATCCAGGGCGGCCAGCTGCATCCGGTCGGCGGTGCGCCCGGCGCGCATGCGCACGACC
TGTCGCGCGACGCGACCGGCGAGGGCCGCTACCTGATCCCGTTCAGCCGCAACACACCCGCGTATCCGACCTTGTCGTTC
GACGACGTGCTCGAAGGGCGCGTGAAGCCCGACGCGCTGCGCGGCAAGATCGTCGTCGTCGGTGTGACGGCGTCGGGGCT
GTACGACCGCTTCGCGACGCCCGTGTCCGGCGAATTCGGGCCGCTCGCCGGCGTGTATATCCACGCCAACGTGCTCGACA
TGCTGGCGACCGGCAGCGCGATCTCGCCCGCGTCGCGCGCCGGGCTGTTCGTCGCGTCGCTGCTGCCGCTCGCCGCGCTG
CTGGGCGGGTTCCTGATGCTGTCGCCGTGGCGTGCGCTGCTGCTGACGCTGAGCCTTGCCGCGCTGTCGGTCGTCGCGAG
CATGGCGCTGCTGTTCGAGGCGCGCATCTGGCTGTCGCCGGCGCCTGCGATCTTCGGGCTGGTCGCCGTCTACCCGATCT
GGAACTGGCGGCGTCTGGAAATGACGATGTCGTACCTGCGTCGCGAACTGCAGCGGCTCGCCGACGAGCCGCACCTGCTG
CCCGAGGCGCCGCGTACGCGTAGCGTCGGCGGCGACGTGCTCGAGCGGCAGATGGCCCTGATGGCACAGGCCGCGCAGCG
CGTGCAGGACATGAAGCGCTTCGTGTGGGACAGCCTCGACAGCATGCCCGAGCCGATCTTCGTGACCGACCTGGCCGGCA
CGGTGCTGATCGCGAACCACGCGGCCAAGCGTTACGGGTCGCGCCTGTCGCTGCCGCTGCCGGAAGGGCGGCCGCTGCGC
ACGGCGCTCGGCGAGCTGACCTTCATGAAGACCGTCGACGGCAACGCCGAACACGACGTGGCGATCCGCGAACACTGGCC
GGCCGTACTCGACCCGACGCTCGAAGCCGAGCACGATGCGATGGCGCGCGGCATCGAGGTGCGCGATCGCGACGGGCTCG
ACCATCTGCTACGCTACGCGGCGTGCACGAACGCGCAGGGCCGCGTGACGGGCTGGATCGCCGGCCTTGTCGACGTGACC
GAACTGCACGCGGCCGAGCGGCAGCGCGAGGAAGCGCTGCACCTGCTGTCGCACGACATGCGCTCGCCGCAATCGTCGAT
TCTCGCGCTCGTCGAGATCGAGCGCGACCGCGCCGAGACCGACGCGATGCGCGGGCTGCTCGCGCGGATCGAGCGCTATG
CGCACCGCGCGCTGTCGCTGGCCGACGAGTTCGTGCAGCTGGCGCGTGCGGAGTCGCAGGTGTACCAGCTCGAGGCGACG
AGCCTCGTCGACGTGCTGATCGATGCGAGCGACGAAGTGTGGCCGCAGGCGCAGGCGAAGCACATTCGCGTCGACACCGA
CGTCGGCACCGAGATGTGCTGGGTGCGCGCCGACCGCTCGCTGATTACGCGCGCGTTCGTGAACCTGCTGAACAATGCAG
TCAAATACAGTCCGTCCGCTACCGTGATCACGTGTACGCTGGCGGTCGAGCACGCGTCGAAACGGATGTTCTGTACGATT
CGCGATCAGGGTTACGGCATTGCGCCGGAAGATCAGCGGCATCTGTTCGAGCGTTTCAAGCGATTCCATGCCGGCGAGCG
GCCCGAAATCTCGGGTTCCGGGCTCGGCATGGCATTCGTGAAGACGGTCGTCACGCGCCATGGGGGCAGCGTGTCGGTCG
ACAGCGAGGTGGGTGTCGGCACCGCGGTGACGGTGTCGCTGCCCGCGATCGACGAGCCGTCCGCCTGA

Upstream 100 bases:

>100_bases
TATTTCTGGGCCGTGACCGTCGAGGAGTTCGAAGGCGGCAAGTTCTACGAGAAGACCAGTCCGGTCAGCGCGTTCACGCT
GTCGCGCTGATTCGCGGCGC

Downstream 100 bases:

>100_bases
CAGGGCCGGGCGCGACGGCAGGCATTTGGGGAAAGCCATGAGAAAGGAATGGGCAGCGACCGCGCTGGCGGCGTCGCTGT
TGACGGGTTGCGCCGGCGTG

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 795; Mature: 795

Protein sequence:

>795_residues
MKPDSVSPRRRLGRRFLIEWIAIGCLGVAVILACAVGRMSASVDGLIYDRLLMLRSLPLSPDVVVVDIDNQSVSALGRWP
WPRDVHARLLDTLARAQPAAVVYDVLFTEPSPEDRAFADAMTHVPTFLPVLLSPEQADGTRAVDPPVAALAARAVGLGHI
NLEVDRDGIVRSVALYESDGRVRWPQLMVPVYRAIQGGQLHPVGGAPGAHAHDLSRDATGEGRYLIPFSRNTPAYPTLSF
DDVLEGRVKPDALRGKIVVVGVTASGLYDRFATPVSGEFGPLAGVYIHANVLDMLATGSAISPASRAGLFVASLLPLAAL
LGGFLMLSPWRALLLTLSLAALSVVASMALLFEARIWLSPAPAIFGLVAVYPIWNWRRLEMTMSYLRRELQRLADEPHLL
PEAPRTRSVGGDVLERQMALMAQAAQRVQDMKRFVWDSLDSMPEPIFVTDLAGTVLIANHAAKRYGSRLSLPLPEGRPLR
TALGELTFMKTVDGNAEHDVAIREHWPAVLDPTLEAEHDAMARGIEVRDRDGLDHLLRYAACTNAQGRVTGWIAGLVDVT
ELHAAERQREEALHLLSHDMRSPQSSILALVEIERDRAETDAMRGLLARIERYAHRALSLADEFVQLARAESQVYQLEAT
SLVDVLIDASDEVWPQAQAKHIRVDTDVGTEMCWVRADRSLITRAFVNLLNNAVKYSPSATVITCTLAVEHASKRMFCTI
RDQGYGIAPEDQRHLFERFKRFHAGERPEISGSGLGMAFVKTVVTRHGGSVSVDSEVGVGTAVTVSLPAIDEPSA

Sequences:

>Translated_795_residues
MKPDSVSPRRRLGRRFLIEWIAIGCLGVAVILACAVGRMSASVDGLIYDRLLMLRSLPLSPDVVVVDIDNQSVSALGRWP
WPRDVHARLLDTLARAQPAAVVYDVLFTEPSPEDRAFADAMTHVPTFLPVLLSPEQADGTRAVDPPVAALAARAVGLGHI
NLEVDRDGIVRSVALYESDGRVRWPQLMVPVYRAIQGGQLHPVGGAPGAHAHDLSRDATGEGRYLIPFSRNTPAYPTLSF
DDVLEGRVKPDALRGKIVVVGVTASGLYDRFATPVSGEFGPLAGVYIHANVLDMLATGSAISPASRAGLFVASLLPLAAL
LGGFLMLSPWRALLLTLSLAALSVVASMALLFEARIWLSPAPAIFGLVAVYPIWNWRRLEMTMSYLRRELQRLADEPHLL
PEAPRTRSVGGDVLERQMALMAQAAQRVQDMKRFVWDSLDSMPEPIFVTDLAGTVLIANHAAKRYGSRLSLPLPEGRPLR
TALGELTFMKTVDGNAEHDVAIREHWPAVLDPTLEAEHDAMARGIEVRDRDGLDHLLRYAACTNAQGRVTGWIAGLVDVT
ELHAAERQREEALHLLSHDMRSPQSSILALVEIERDRAETDAMRGLLARIERYAHRALSLADEFVQLARAESQVYQLEAT
SLVDVLIDASDEVWPQAQAKHIRVDTDVGTEMCWVRADRSLITRAFVNLLNNAVKYSPSATVITCTLAVEHASKRMFCTI
RDQGYGIAPEDQRHLFERFKRFHAGERPEISGSGLGMAFVKTVVTRHGGSVSVDSEVGVGTAVTVSLPAIDEPSA
>Mature_795_residues
MKPDSVSPRRRLGRRFLIEWIAIGCLGVAVILACAVGRMSASVDGLIYDRLLMLRSLPLSPDVVVVDIDNQSVSALGRWP
WPRDVHARLLDTLARAQPAAVVYDVLFTEPSPEDRAFADAMTHVPTFLPVLLSPEQADGTRAVDPPVAALAARAVGLGHI
NLEVDRDGIVRSVALYESDGRVRWPQLMVPVYRAIQGGQLHPVGGAPGAHAHDLSRDATGEGRYLIPFSRNTPAYPTLSF
DDVLEGRVKPDALRGKIVVVGVTASGLYDRFATPVSGEFGPLAGVYIHANVLDMLATGSAISPASRAGLFVASLLPLAAL
LGGFLMLSPWRALLLTLSLAALSVVASMALLFEARIWLSPAPAIFGLVAVYPIWNWRRLEMTMSYLRRELQRLADEPHLL
PEAPRTRSVGGDVLERQMALMAQAAQRVQDMKRFVWDSLDSMPEPIFVTDLAGTVLIANHAAKRYGSRLSLPLPEGRPLR
TALGELTFMKTVDGNAEHDVAIREHWPAVLDPTLEAEHDAMARGIEVRDRDGLDHLLRYAACTNAQGRVTGWIAGLVDVT
ELHAAERQREEALHLLSHDMRSPQSSILALVEIERDRAETDAMRGLLARIERYAHRALSLADEFVQLARAESQVYQLEAT
SLVDVLIDASDEVWPQAQAKHIRVDTDVGTEMCWVRADRSLITRAFVNLLNNAVKYSPSATVITCTLAVEHASKRMFCTI
RDQGYGIAPEDQRHLFERFKRFHAGERPEISGSGLGMAFVKTVVTRHGGSVSVDSEVGVGTAVTVSLPAIDEPSA

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: COG4252

COG function: function code T; Predicted transmembrane sensor domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=377, Percent_Identity=26.525198938992, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI1786600, Length=236, Percent_Identity=28.3898305084746, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1786783, Length=222, Percent_Identity=27.9279279279279, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI1788549, Length=299, Percent_Identity=25.0836120401338, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI1786912, Length=237, Percent_Identity=26.1603375527426, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI1787894, Length=241, Percent_Identity=27.8008298755187, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1789149, Length=226, Percent_Identity=23.4513274336283, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI1790436, Length=232, Percent_Identity=28.448275862069, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI145693157, Length=230, Percent_Identity=22.1739130434783, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI1790346, Length=239, Percent_Identity=25.1046025104602, Blast_Score=66, Evalue=8e-12,
Organism=Escherichia coli, GI48994928, Length=257, Percent_Identity=24.9027237354086, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1788393, Length=235, Percent_Identity=22.9787234042553, Blast_Score=63, Evalue=6e-11,
Organism=Escherichia coli, GI1789808, Length=214, Percent_Identity=27.1028037383178, Blast_Score=63, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 86888; Mature: 86888

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPDSVSPRRRLGRRFLIEWIAIGCLGVAVILACAVGRMSASVDGLIYDRLLMLRSLPLS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PDVVVVDIDNQSVSALGRWPWPRDVHARLLDTLARAQPAAVVYDVLFTEPSPEDRAFADA
CCEEEEEECCCCHHHHCCCCCCHHHHHHHHHHHHHCCCHHEEEHHHCCCCCCCHHHHHHH
MTHVPTFLPVLLSPEQADGTRAVDPPVAALAARAVGLGHINLEVDRDGIVRSVALYESDG
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEEEECCCCCEEEEEEEECCC
RVRWPQLMVPVYRAIQGGQLHPVGGAPGAHAHDLSRDATGEGRYLIPFSRNTPAYPTLSF
CEECHHHHHHHHHHHCCCCEECCCCCCCCCHHHCCCCCCCCCCEEEEECCCCCCCCCCCH
DDVLEGRVKPDALRGKIVVVGVTASGLYDRFATPVSGEFGPLAGVYIHANVLDMLATGSA
HHHHCCCCCCHHHCCEEEEEEECCHHHHHHHCCCCCCCCCCCEEEEEEHHHHHHHHCCCC
ISPASRAGLFVASLLPLAALLGGFLMLSPWRALLLTLSLAALSVVASMALLFEARIWLSP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
APAIFGLVAVYPIWNWRRLEMTMSYLRRELQRLADEPHLLPEAPRTRSVGGDVLERQMAL
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHH
MAQAAQRVQDMKRFVWDSLDSMPEPIFVTDLAGTVLIANHAAKRYGSRLSLPLPEGRPLR
HHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHEEHHHHHHHCCCEECCCCCCCCCHH
TALGELTFMKTVDGNAEHDVAIREHWPAVLDPTLEAEHDAMARGIEVRDRDGLDHLLRYA
HHHHHHHEEEECCCCCCCCEEHHHCCCHHCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHH
ACTNAQGRVTGWIAGLVDVTELHAAERQREEALHLLSHDMRSPQSSILALVEIERDRAET
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEEEHHHHHHH
DAMRGLLARIERYAHRALSLADEFVQLARAESQVYQLEATSLVDVLIDASDEVWPQAQAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
HIRVDTDVGTEMCWVRADRSLITRAFVNLLNNAVKYSPSATVITCTLAVEHASKRMFCTI
EEEEECCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCEEEEEE
RDQGYGIAPEDQRHLFERFKRFHAGERPEISGSGLGMAFVKTVVTRHGGSVSVDSEVGVG
ECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCC
TAVTVSLPAIDEPSA
EEEEEEECCCCCCCC
>Mature Secondary Structure
MKPDSVSPRRRLGRRFLIEWIAIGCLGVAVILACAVGRMSASVDGLIYDRLLMLRSLPLS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PDVVVVDIDNQSVSALGRWPWPRDVHARLLDTLARAQPAAVVYDVLFTEPSPEDRAFADA
CCEEEEEECCCCHHHHCCCCCCHHHHHHHHHHHHHCCCHHEEEHHHCCCCCCCHHHHHHH
MTHVPTFLPVLLSPEQADGTRAVDPPVAALAARAVGLGHINLEVDRDGIVRSVALYESDG
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEEEECCCCCEEEEEEEECCC
RVRWPQLMVPVYRAIQGGQLHPVGGAPGAHAHDLSRDATGEGRYLIPFSRNTPAYPTLSF
CEECHHHHHHHHHHHCCCCEECCCCCCCCCHHHCCCCCCCCCCEEEEECCCCCCCCCCCH
DDVLEGRVKPDALRGKIVVVGVTASGLYDRFATPVSGEFGPLAGVYIHANVLDMLATGSA
HHHHCCCCCCHHHCCEEEEEEECCHHHHHHHCCCCCCCCCCCEEEEEEHHHHHHHHCCCC
ISPASRAGLFVASLLPLAALLGGFLMLSPWRALLLTLSLAALSVVASMALLFEARIWLSP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
APAIFGLVAVYPIWNWRRLEMTMSYLRRELQRLADEPHLLPEAPRTRSVGGDVLERQMAL
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHH
MAQAAQRVQDMKRFVWDSLDSMPEPIFVTDLAGTVLIANHAAKRYGSRLSLPLPEGRPLR
HHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHEEHHHHHHHCCCEECCCCCCCCCHH
TALGELTFMKTVDGNAEHDVAIREHWPAVLDPTLEAEHDAMARGIEVRDRDGLDHLLRYA
HHHHHHHEEEECCCCCCCCEEHHHCCCHHCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHH
ACTNAQGRVTGWIAGLVDVTELHAAERQREEALHLLSHDMRSPQSSILALVEIERDRAET
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEEEHHHHHHH
DAMRGLLARIERYAHRALSLADEFVQLARAESQVYQLEATSLVDVLIDASDEVWPQAQAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
HIRVDTDVGTEMCWVRADRSLITRAFVNLLNNAVKYSPSATVITCTLAVEHASKRMFCTI
EEEEECCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCEEEEEE
RDQGYGIAPEDQRHLFERFKRFHAGERPEISGSGLGMAFVKTVVTRHGGSVSVDSEVGVG
ECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCC
TAVTVSLPAIDEPSA
EEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]