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The map label for this gene is pilC [H]

Identifier: 78065138

GI number: 78065138

Start: 547813

End: 549024

Strand: Reverse

Name: pilC [H]

Synonym: Bcep18194_A3662

Alternate gene names: 78065138

Gene position: 549024-547813 (Counterclockwise)

Preceding gene: 78065139

Following gene: 78065137

Centisome position: 14.86

GC content: 72.61

Gene sequence:

>1212_bases
ATGAGCATGCGCACGCCGCCGCGCGAAACCCGCTTCGCGTGGCGCGGCCGCCGTCGCGACGGCACGTCGCGCCGAGGGAA
CGTCATCGCATTCGACGCCGCGAGCGCACGTGCCGCGCTCGCACGCGACGGCATCGCCGTGCTGTCGCTCGACGTCCGCG
GGCCGGCCCGGGCGCCAACGGCCAGCGCGCGGGACGTCACGCGCTTCACGCGCCAGCTCGCGAGCCTGCTGCAGGCCGGA
TTGCCGCTCGCGCCGTCGCTCGAGATGCTCGCGCGTACGCGGCCGCACGACGGCCTGCCGCGCATCGCCGCCGGTCTCGC
GCGCGAAATCGTCGGCGGCCGGCGCTTCGCCGAGGCACTCGCACGCTATCCATCCCAGTTCGGCACGCTGTATCGCCAGC
TGATCGAGGTCGGCGAAGCGTCCGGCTCGCTTGGCATCGTGCTGACACGGCTTGCGGAACACCGCGAGCGCACCGACGCG
CAGTGGCGCAAGCTGCGCGCCGCGCTCGCCTATCCTGCGGCCGTCATCCTGTTCGGGCTCGCGATCTCGGCGGCGTTGAT
GGTGTGGGTCGTGCCGACGTTCCGCCAGATCTTCGACGGTTTTGGCGCCGCACTGCCGGCGCCGACTCGCGCGCTGCTCG
CGCTGTCCTCCGCGCTGTCGGCGTGGGGCGGTGTGCTCGCTGCCGGTATGGCAGCAGCCGGGCTGGCTGCACATCACGCG
CTGCGGCGGTCGGCGCCGCTGCGCCAAGCTGTCGCGCGGCACCTGCTGCACGCGCCGCTCGCGGGTGGTGCGCTCAGCCG
GTACGCAGCCGCACGCTGGTGCCGCTCGCTTGCGACGCTGCTCGGCGCCGGCGTGCCGCTCGCCGACGCCTTTGCCACGC
TCGAGCGCACCGCCGGCCATCCTGTGTTCGAGCATGCCACCGCGCACATCGCAGCCCGCGTGCTGCGCGGCGCGCGTCTC
GCTGATGCAATGCAGTCGGCCGGTTGCTTTCCGGACGACGTCGTGCAGCCGATCGCCGTCGCCGAGGAGACGGGGGCGCT
CGACATGATGCTCGCCGACATCGCCGCGTTGTGCGAACGCCAGCTCGACGCGCGTCTCGACGCACTCGCCGCGCTCGGCG
AACCGCTGATCGTGATCGTACTGGGTGCACTCGTCGGCGGCCTCGTGATCGCGATGTACCTGCCCATCCTTCAGCTCGGC
AACGTGGTGTAG

Upstream 100 bases:

>100_bases
TGGCGGCCGAAGGCGTGCGCAGTCTGCGCGACGCGGCGCTCGCGCGCGTTCACGACGGCACGACCAGCATCGCGGAAGCC
CTCGCCGCGACACCTGCCAC

Downstream 100 bases:

>100_bases
CATCGCAACCGATTCTGTCGCCTTTTAGTCCGAACCTTGAGCCTCATGACGCCAGCGCCCCTGTCCGCCGTTCCCGATTC
GCCCGAGAGCACGCTGCTCG

Product: type II secretion system protein F

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MSMRTPPRETRFAWRGRRRDGTSRRGNVIAFDAASARAALARDGIAVLSLDVRGPARAPTASARDVTRFTRQLASLLQAG
LPLAPSLEMLARTRPHDGLPRIAAGLAREIVGGRRFAEALARYPSQFGTLYRQLIEVGEASGSLGIVLTRLAEHRERTDA
QWRKLRAALAYPAAVILFGLAISAALMVWVVPTFRQIFDGFGAALPAPTRALLALSSALSAWGGVLAAGMAAAGLAAHHA
LRRSAPLRQAVARHLLHAPLAGGALSRYAAARWCRSLATLLGAGVPLADAFATLERTAGHPVFEHATAHIAARVLRGARL
ADAMQSAGCFPDDVVQPIAVAEETGALDMMLADIAALCERQLDARLDALAALGEPLIVIVLGALVGGLVIAMYLPILQLG
NVV

Sequences:

>Translated_403_residues
MSMRTPPRETRFAWRGRRRDGTSRRGNVIAFDAASARAALARDGIAVLSLDVRGPARAPTASARDVTRFTRQLASLLQAG
LPLAPSLEMLARTRPHDGLPRIAAGLAREIVGGRRFAEALARYPSQFGTLYRQLIEVGEASGSLGIVLTRLAEHRERTDA
QWRKLRAALAYPAAVILFGLAISAALMVWVVPTFRQIFDGFGAALPAPTRALLALSSALSAWGGVLAAGMAAAGLAAHHA
LRRSAPLRQAVARHLLHAPLAGGALSRYAAARWCRSLATLLGAGVPLADAFATLERTAGHPVFEHATAHIAARVLRGARL
ADAMQSAGCFPDDVVQPIAVAEETGALDMMLADIAALCERQLDARLDALAALGEPLIVIVLGALVGGLVIAMYLPILQLG
NVV
>Mature_402_residues
SMRTPPRETRFAWRGRRRDGTSRRGNVIAFDAASARAALARDGIAVLSLDVRGPARAPTASARDVTRFTRQLASLLQAGL
PLAPSLEMLARTRPHDGLPRIAAGLAREIVGGRRFAEALARYPSQFGTLYRQLIEVGEASGSLGIVLTRLAEHRERTDAQ
WRKLRAALAYPAAVILFGLAISAALMVWVVPTFRQIFDGFGAALPAPTRALLALSSALSAWGGVLAAGMAAAGLAAHHAL
RRSAPLRQAVARHLLHAPLAGGALSRYAAARWCRSLATLLGAGVPLADAFATLERTAGHPVFEHATAHIAARVLRGARLA
DAMQSAGCFPDDVVQPIAVAEETGALDMMLADIAALCERQLDARLDALAALGEPLIVIVLGALVGGLVIAMYLPILQLGN
VV

Specific function: Involved in the translocation of the type IV pilin (pilA) [H]

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1789724, Length=399, Percent_Identity=28.0701754385965, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1786295, Length=390, Percent_Identity=27.9487179487179, Blast_Score=124, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 42518; Mature: 42387

Theoretical pI: Translated: 11.63; Mature: 11.63

Prosite motif: PS00874 T2SP_F

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMRTPPRETRFAWRGRRRDGTSRRGNVIAFDAASARAALARDGIAVLSLDVRGPARAPT
CCCCCCCHHHHHHHCCCCCCCCCCCCCEEEEECHHHHHHHHHCCEEEEEEECCCCCCCCC
ASARDVTRFTRQLASLLQAGLPLAPSLEMLARTRPHDGLPRIAAGLAREIVGGRRFAEAL
CCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ARYPSQFGTLYRQLIEVGEASGSLGIVLTRLAEHRERTDAQWRKLRAALAYPAAVILFGL
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AISAALMVWVVPTFRQIFDGFGAALPAPTRALLALSSALSAWGGVLAAGMAAAGLAAHHA
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRRSAPLRQAVARHLLHAPLAGGALSRYAAARWCRSLATLLGAGVPLADAFATLERTAGH
HHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
PVFEHATAHIAARVLRGARLADAMQSAGCFPDDVVQPIAVAEETGALDMMLADIAALCER
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
QLDARLDALAALGEPLIVIVLGALVGGLVIAMYLPILQLGNVV
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SMRTPPRETRFAWRGRRRDGTSRRGNVIAFDAASARAALARDGIAVLSLDVRGPARAPT
CCCCCCHHHHHHHCCCCCCCCCCCCCEEEEECHHHHHHHHHCCEEEEEEECCCCCCCCC
ASARDVTRFTRQLASLLQAGLPLAPSLEMLARTRPHDGLPRIAAGLAREIVGGRRFAEAL
CCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ARYPSQFGTLYRQLIEVGEASGSLGIVLTRLAEHRERTDAQWRKLRAALAYPAAVILFGL
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AISAALMVWVVPTFRQIFDGFGAALPAPTRALLALSSALSAWGGVLAAGMAAAGLAAHHA
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRRSAPLRQAVARHLLHAPLAGGALSRYAAARWCRSLATLLGAGVPLADAFATLERTAGH
HHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
PVFEHATAHIAARVLRGARLADAMQSAGCFPDDVVQPIAVAEETGALDMMLADIAALCER
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
QLDARLDALAALGEPLIVIVLGALVGGLVIAMYLPILQLGNVV
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1971619; 10984043 [H]