BacMap

Definition	Burkholderia sp. 383 chromosome 1, complete genome.
Accession	NC_007510
Length	3,694,126

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The map label for this gene is fadB1 [H]

Identifier: 78065107

GI number: 78065107

Start: 506019

End: 506795

Strand: Direct

Name: fadB1 [H]

Synonym: Bcep18194_A3631

Alternate gene names: 78065107

Gene position: 506019-506795 (Clockwise)

Preceding gene: 78065101

Following gene: 78065108

Centisome position: 13.7

GC content: 64.22

Gene sequence:

>777_bases
ATGGCTTACGAGAACATCCTGGTGGAGACCCGGGGGCGTGTCGGGCTGGTTACGCTGAACCGTCCGAAGGCGCTGAATGC
GCTGAACGATGCGCTGATGGATGAGCTGGGTGACGCGCTGAAGGCGTTCGATGCGGACGATGGTATCGGTGCAATCGTCG
TGACCGGGAGCGAGAAGGCGTTCGCGGCCGGCGCAGATATCGGCATGATGGCGACCTACTCCTATATGGATGCCTACCGG
GGCGACTACATCACGCGCAACTGGGAGACGGTCCGCGAAATTCGCAAGCCGATCATTGCGGCGGTTTCTGGCTTTGCGCT
GGGTGGCGGCTGCGAGCTGGCCATGATGTGCGACATCATCTTCGCGGCGGACACGGCCAAGTTCGGCCAGCCGGAAATCA
AGCTGGGCGTCATGCCGGGGGCGGGCGGCACGCAGCGCCTGCCGCGCGCGGTGTCTAAGGCGAAGGCGATGGACATGTGC
CTGACCGCGCGTTTCATGGATGCTGCCGAAGCGGAGCGCGCGGGGCTCGTGTCGCGCGTATTGCCGGCCGACACGCTGCT
TGATGAGGCGCTTGCCGCCGCGGCGACGATCGCCGAGTTTTCGCTGCCGGCGGTCATGATGGTCAAGGAGTCGGTGAACC
GCGCGTACGAGACGACGCTGGCCGAAGGCGTCCACTTCGAGCGTCGGCTGTTTCATTCGCTGTTCGCGACCGAAGACCAG
AAGGAAGGGATGGCGGCATTCGTCGAGAAACGGAAGCCGGTGTTCAAGCACCGCTGA

Upstream 100 bases:

>100_bases
TTGGATCGATTAATTAACCGACCGGTTGGTCGGAGAATGGTAGCATCAAACTATTCGCATGTGCGAGGCGTTTCTCATTT
CATTGATCGAGGAGAAATAG

Downstream 100 bases:

>100_bases
TCGGGCTACTTGGGTAGTTGGCCGGCGACTGGTGGGTATCGGTTGTCGGCGTGATTGCCGGGCCCGCCGAGCCCCAAGCC
CCCGTGCGCGTCAGCGCACG

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MAYENILVETRGRVGLVTLNRPKALNALNDALMDELGDALKAFDADDGIGAIVVTGSEKAFAAGADIGMMATYSYMDAYR
GDYITRNWETVREIRKPIIAAVSGFALGGGCELAMMCDIIFAADTAKFGQPEIKLGVMPGAGGTQRLPRAVSKAKAMDMC
LTARFMDAAEAERAGLVSRVLPADTLLDEALAAAATIAEFSLPAVMMVKESVNRAYETTLAEGVHFERRLFHSLFATEDQ
KEGMAAFVEKRKPVFKHR

Sequences:

>Translated_258_residues
MAYENILVETRGRVGLVTLNRPKALNALNDALMDELGDALKAFDADDGIGAIVVTGSEKAFAAGADIGMMATYSYMDAYR
GDYITRNWETVREIRKPIIAAVSGFALGGGCELAMMCDIIFAADTAKFGQPEIKLGVMPGAGGTQRLPRAVSKAKAMDMC
LTARFMDAAEAERAGLVSRVLPADTLLDEALAAAATIAEFSLPAVMMVKESVNRAYETTLAEGVHFERRLFHSLFATEDQ
KEGMAAFVEKRKPVFKHR
>Mature_257_residues
AYENILVETRGRVGLVTLNRPKALNALNDALMDELGDALKAFDADDGIGAIVVTGSEKAFAAGADIGMMATYSYMDAYRG
DYITRNWETVREIRKPIIAAVSGFALGGGCELAMMCDIIFAADTAKFGQPEIKLGVMPGAGGTQRLPRAVSKAKAMDMCL
TARFMDAAEAERAGLVSRVLPADTLLDEALAAAATIAEFSLPAVMMVKESVNRAYETTLAEGVHFERRLFHSLFATEDQK
EGMAAFVEKRKPVFKHR

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=259, Percent_Identity=55.984555984556, Blast_Score=295, Evalue=3e-80,
Organism=Homo sapiens, GI4502327, Length=256, Percent_Identity=36.328125, Blast_Score=121, Evalue=7e-28,
Organism=Homo sapiens, GI70995211, Length=266, Percent_Identity=33.4586466165414, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI31542718, Length=245, Percent_Identity=30.2040816326531, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI20127408, Length=177, Percent_Identity=36.7231638418079, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI68989263, Length=203, Percent_Identity=33.9901477832512, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI150378541, Length=244, Percent_Identity=31.5573770491803, Blast_Score=95, Evalue=5e-20,
Organism=Homo sapiens, GI37594471, Length=214, Percent_Identity=29.4392523364486, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI37594469, Length=214, Percent_Identity=29.4392523364486, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI45643119, Length=246, Percent_Identity=28.4552845528455, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI260275230, Length=246, Percent_Identity=28.4552845528455, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI260274832, Length=246, Percent_Identity=28.4552845528455, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI4757968, Length=257, Percent_Identity=25.2918287937743, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI49355787, Length=257, Percent_Identity=25.2918287937743, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI25453481, Length=256, Percent_Identity=25, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI51538573, Length=256, Percent_Identity=25, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI4757966, Length=211, Percent_Identity=27.4881516587678, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI51538581, Length=211, Percent_Identity=27.4881516587678, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI213417737, Length=228, Percent_Identity=25, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI157694516, Length=228, Percent_Identity=25, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI221136756, Length=256, Percent_Identity=24.609375, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI221136753, Length=256, Percent_Identity=24.609375, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI221307494, Length=210, Percent_Identity=28.0952380952381, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI116235487, Length=211, Percent_Identity=27.4881516587678, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI261878539, Length=108, Percent_Identity=34.2592592592593, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1787659, Length=253, Percent_Identity=46.2450592885375, Blast_Score=221, Evalue=3e-59,
Organism=Escherichia coli, GI221142681, Length=260, Percent_Identity=36.1538461538462, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1788597, Length=261, Percent_Identity=32.9501915708812, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1787660, Length=266, Percent_Identity=32.7067669172932, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI87082183, Length=265, Percent_Identity=32.0754716981132, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788682, Length=207, Percent_Identity=30.9178743961353, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1790281, Length=180, Percent_Identity=29.4444444444444, Blast_Score=91, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17554946, Length=260, Percent_Identity=55.3846153846154, Blast_Score=293, Evalue=5e-80,
Organism=Caenorhabditis elegans, GI25145438, Length=243, Percent_Identity=53.9094650205761, Blast_Score=261, Evalue=2e-70,
Organism=Caenorhabditis elegans, GI17540714, Length=223, Percent_Identity=31.8385650224215, Blast_Score=120, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17560910, Length=259, Percent_Identity=33.976833976834, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17540306, Length=237, Percent_Identity=32.4894514767932, Blast_Score=116, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI17558304, Length=182, Percent_Identity=36.2637362637363, Blast_Score=108, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17534483, Length=256, Percent_Identity=27.734375, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI25144276, Length=182, Percent_Identity=35.7142857142857, Blast_Score=103, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17508951, Length=182, Percent_Identity=35.7142857142857, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17508953, Length=182, Percent_Identity=35.7142857142857, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17536985, Length=266, Percent_Identity=30.8270676691729, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI25144157, Length=218, Percent_Identity=30.7339449541284, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI25144160, Length=218, Percent_Identity=30.7339449541284, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17549921, Length=213, Percent_Identity=32.3943661971831, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17535521, Length=259, Percent_Identity=24.3243243243243, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI25141363, Length=178, Percent_Identity=30.3370786516854, Blast_Score=71, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6320241, Length=194, Percent_Identity=27.319587628866, Blast_Score=89, Evalue=9e-19,
Organism=Drosophila melanogaster, GI20129971, Length=258, Percent_Identity=58.1395348837209, Blast_Score=298, Evalue=2e-81,
Organism=Drosophila melanogaster, GI24653477, Length=258, Percent_Identity=58.1395348837209, Blast_Score=298, Evalue=2e-81,
Organism=Drosophila melanogaster, GI24653139, Length=266, Percent_Identity=37.593984962406, Blast_Score=156, Evalue=1e-38,
Organism=Drosophila melanogaster, GI21357171, Length=260, Percent_Identity=32.6923076923077, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24650670, Length=213, Percent_Identity=34.7417840375587, Blast_Score=118, Evalue=4e-27,
Organism=Drosophila melanogaster, GI19920382, Length=255, Percent_Identity=34.1176470588235, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI19922422, Length=253, Percent_Identity=27.6679841897233, Blast_Score=104, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24654903, Length=191, Percent_Identity=28.2722513089005, Blast_Score=94, Evalue=7e-20,
Organism=Drosophila melanogaster, GI19921000, Length=170, Percent_Identity=35.2941176470588, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24583077, Length=170, Percent_Identity=35.2941176470588, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24583079, Length=170, Percent_Identity=35.2941176470588, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28571730, Length=241, Percent_Identity=26.5560165975104, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI28571729, Length=241, Percent_Identity=26.5560165975104, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 27869; Mature: 27737

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYENILVETRGRVGLVTLNRPKALNALNDALMDELGDALKAFDADDGIGAIVVTGSEKA
CCCCCEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCC
FAAGADIGMMATYSYMDAYRGDYITRNWETVREIRKPIIAAVSGFALGGGCELAMMCDII
EECCCCHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
FAADTAKFGQPEIKLGVMPGAGGTQRLPRAVSKAKAMDMCLTARFMDAAEAERAGLVSRV
HHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPADTLLDEALAAAATIAEFSLPAVMMVKESVNRAYETTLAEGVHFERRLFHSLFATEDQ
CCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCH
KEGMAAFVEKRKPVFKHR
HHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AYENILVETRGRVGLVTLNRPKALNALNDALMDELGDALKAFDADDGIGAIVVTGSEKA
CCCCEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCC
FAAGADIGMMATYSYMDAYRGDYITRNWETVREIRKPIIAAVSGFALGGGCELAMMCDII
EECCCCHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
FAADTAKFGQPEIKLGVMPGAGGTQRLPRAVSKAKAMDMCLTARFMDAAEAERAGLVSRV
HHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPADTLLDEALAAAATIAEFSLPAVMMVKESVNRAYETTLAEGVHFERRLFHSLFATEDQ
CCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCH
KEGMAAFVEKRKPVFKHR
HHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7751302; 11481430 [H]