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The map label for this gene is sdaA [H]

Identifier: 78064798

GI number: 78064798

Start: 166108

End: 167496

Strand: Reverse

Name: sdaA [H]

Synonym: Bcep18194_A3321

Alternate gene names: 78064798

Gene position: 167496-166108 (Counterclockwise)

Preceding gene: 78064799

Following gene: 78064795

Centisome position: 4.53

GC content: 68.25

Gene sequence:

>1389_bases
ATGGCAGTCAGCGTCTTTGACCTCTTCAAGATCGGTATCGGTCCGTCCAGCTCGCATACGGTCGGGCCGATGCGCGCGGC
GCTGATGTTCGTCCAGGGCCTCGAGCGCGACGGACAACTCGACGCAACGGCACACGTGAAGGTCGAGCTGTACGGCTCGC
TCGGCGCGACCGGCAAAGGCCACGGCACCGACCGCGGCGTGATGCTCGGCCTGCTCGGTGACGCGCCCGACACCGTCGAT
CCCGAAACCATCGACGCGCGGCTGGAAGACATCCGCAAATCGAAGAAGCTCGCGCTGCTCGGCACGCATCCGGTGCCGTT
CGTGCTGAAGGAGAACATCGCGTTCTACCGCCAGGCGCTGCCCGAGCACCCGAACGGGATGAAGCTGCGCGCGTCCGACG
CGAGCGGCAACGTGCTGGTCGAGCGCACCTACCTGTCGGTCGGCGGCGGCTTCGTCGTGACGGCCGGCGCACCGAACACG
AAGGTGCTGAGCGCGGCCGAGCAGATGACGCACCCGTTCCGCACCGGCGCCGAGCTGCTCGCGCTGACCGAGTCGACCGG
CAAGTCGATCGCGCAGCTGATGTGGGAAAACGAGCGCGCGTGGCACACCGAGGAAGAGACGCGCGACGGCCTGCTGAAGA
TCTGGGCCGTGATGCAGTCGTGCGTGTCGCGCGGCTGCGGAATCGGCAACCCGGAAGCCGACGGCAACCTGCCCGGCCCG
TTCCAGGTCAAGCGCCGCGCGCCGCAGCTGTACCGCACGCTGACGGGCAGCCCGGAGCGCGCGCTGCAGGACCCGCTGTC
GATGATCGACTGGATCAACCTGTACGCGATCGCGGTCAACGAGGAAAACGCGGCCGGCGGCCGCGTCGTCACCGCGCCGA
CCAACGGCGCGGCCGGCATCATCCCGGCCGTGCTGCACTACTACACGCGCTTCACGCCCGGCGCGAACGAACAGGGCGTG
ATCGACTTCCTGCTGACGGCCGCCGCGATCGGCATTCTTTACAAGCTGAATGCGTCGATCTCCGGTGCGGAAGTCGGCTG
CCAGGGCGAAGTGGGCGTCGCGTGCTCGATGGCGGCCGGCGCGCTCGCGGCCGTGCTCGGCGGCACGCCGCACCAGGTCG
AGAACGCAGCCGAGATCGGGATGGAACACAACCTCGGCCTTACCTGCGACCCGGTCGGCGGGATGGTGCAGATCCCGTGC
ATCGAGCGCAACGCGATGGCGTCGGTGAAGGCGGTCAACGCGGCGCGCATGGCGCTGCGCGGCGACGGCTCGCACTACGT
GTCGCTCGACTCCGTGATCAAGACGATGCGCGAGACGGGTGCCGACATGAAGACGAAGTACAAGGAAACGTCGCGCGGCG
GGCTGGCGGTCAATATCGTCGAGTGCTGA

Upstream 100 bases:

>100_bases
CGTCGCGCAGCAGCTTTCCCCAACGCCGCCCGCATGGCTCGCCGCGTGCCTGCCATTGCAGGCGCGCTAGCATTATTCTT
AAAGCAAGGCAGGAATCAAC

Downstream 100 bases:

>100_bases
TGCCGGATCCGGCGGTCGCGCGGGACGGATCAATCTCCCGCATGACCGCCGGACACGGTACCCGGCACTAGTCGTTCAGC
CAGTTTTCCAGCCGCAATCC

Product: L-serine ammonia-lyase

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 462; Mature: 461

Protein sequence:

>462_residues
MAVSVFDLFKIGIGPSSSHTVGPMRAALMFVQGLERDGQLDATAHVKVELYGSLGATGKGHGTDRGVMLGLLGDAPDTVD
PETIDARLEDIRKSKKLALLGTHPVPFVLKENIAFYRQALPEHPNGMKLRASDASGNVLVERTYLSVGGGFVVTAGAPNT
KVLSAAEQMTHPFRTGAELLALTESTGKSIAQLMWENERAWHTEEETRDGLLKIWAVMQSCVSRGCGIGNPEADGNLPGP
FQVKRRAPQLYRTLTGSPERALQDPLSMIDWINLYAIAVNEENAAGGRVVTAPTNGAAGIIPAVLHYYTRFTPGANEQGV
IDFLLTAAAIGILYKLNASISGAEVGCQGEVGVACSMAAGALAAVLGGTPHQVENAAEIGMEHNLGLTCDPVGGMVQIPC
IERNAMASVKAVNAARMALRGDGSHYVSLDSVIKTMRETGADMKTKYKETSRGGLAVNIVEC

Sequences:

>Translated_462_residues
MAVSVFDLFKIGIGPSSSHTVGPMRAALMFVQGLERDGQLDATAHVKVELYGSLGATGKGHGTDRGVMLGLLGDAPDTVD
PETIDARLEDIRKSKKLALLGTHPVPFVLKENIAFYRQALPEHPNGMKLRASDASGNVLVERTYLSVGGGFVVTAGAPNT
KVLSAAEQMTHPFRTGAELLALTESTGKSIAQLMWENERAWHTEEETRDGLLKIWAVMQSCVSRGCGIGNPEADGNLPGP
FQVKRRAPQLYRTLTGSPERALQDPLSMIDWINLYAIAVNEENAAGGRVVTAPTNGAAGIIPAVLHYYTRFTPGANEQGV
IDFLLTAAAIGILYKLNASISGAEVGCQGEVGVACSMAAGALAAVLGGTPHQVENAAEIGMEHNLGLTCDPVGGMVQIPC
IERNAMASVKAVNAARMALRGDGSHYVSLDSVIKTMRETGADMKTKYKETSRGGLAVNIVEC
>Mature_461_residues
AVSVFDLFKIGIGPSSSHTVGPMRAALMFVQGLERDGQLDATAHVKVELYGSLGATGKGHGTDRGVMLGLLGDAPDTVDP
ETIDARLEDIRKSKKLALLGTHPVPFVLKENIAFYRQALPEHPNGMKLRASDASGNVLVERTYLSVGGGFVVTAGAPNTK
VLSAAEQMTHPFRTGAELLALTESTGKSIAQLMWENERAWHTEEETRDGLLKIWAVMQSCVSRGCGIGNPEADGNLPGPF
QVKRRAPQLYRTLTGSPERALQDPLSMIDWINLYAIAVNEENAAGGRVVTAPTNGAAGIIPAVLHYYTRFTPGANEQGVI
DFLLTAAAIGILYKLNASISGAEVGCQGEVGVACSMAAGALAAVLGGTPHQVENAAEIGMEHNLGLTCDPVGGMVQIPCI
ERNAMASVKAVNAARMALRGDGSHYVSLDSVIKTMRETGADMKTKYKETSRGGLAVNIVEC

Specific function: Deaminates Also Threonine, Particularly When It Is Present In High Concentration. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1788116, Length=463, Percent_Identity=52.9157667386609, Blast_Score=473, Evalue=1e-134,
Organism=Escherichia coli, GI48994925, Length=461, Percent_Identity=54.4468546637744, Blast_Score=469, Evalue=1e-133,
Organism=Escherichia coli, GI1789161, Length=461, Percent_Identity=53.1453362255965, Blast_Score=463, Evalue=1e-131,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 48804; Mature: 48673

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVSVFDLFKIGIGPSSSHTVGPMRAALMFVQGLERDGQLDATAHVKVELYGSLGATGKG
CEEEHEEHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEECCCCCCCC
HGTDRGVMLGLLGDAPDTVDPETIDARLEDIRKSKKLALLGTHPVPFVLKENIAFYRQAL
CCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHC
PEHPNGMKLRASDASGNVLVERTYLSVGGGFVVTAGAPNTKVLSAAEQMTHPFRTGAELL
CCCCCCCEEEECCCCCCEEEEEEEEEECCCEEEECCCCCHHHHHHHHHHCCCHHCCCCEE
ALTESTGKSIAQLMWENERAWHTEEETRDGLLKIWAVMQSCVSRGCGIGNPEADGNLPGP
EEEHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
FQVKRRAPQLYRTLTGSPERALQDPLSMIDWINLYAIAVNEENAAGGRVVTAPTNGAAGI
HHHHHHCHHHHHHHCCCHHHHHHHHHHHHHHEEEEEEEEECCCCCCCEEEECCCCCCCHH
IPAVLHYYTRFTPGANEQGVIDFLLTAAAIGILYKLNASISGAEVGCQGEVGVACSMAAG
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCHHHHHHHH
ALAAVLGGTPHQVENAAEIGMEHNLGLTCDPVGGMVQIPCIERNAMASVKAVNAARMALR
HHHHHHCCCHHHHHHHHHCCCCCCCCEEECCCCCEEEEEEECCCHHHHHHHHHHHHHEEE
GDGSHYVSLDSVIKTMRETGADMKTKYKETSRGGLAVNIVEC
CCCCCEEEHHHHHHHHHHCCCCHHHHHHHCCCCCEEEEEEEC
>Mature Secondary Structure 
AVSVFDLFKIGIGPSSSHTVGPMRAALMFVQGLERDGQLDATAHVKVELYGSLGATGKG
EEEHEEHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEECCCCCCCC
HGTDRGVMLGLLGDAPDTVDPETIDARLEDIRKSKKLALLGTHPVPFVLKENIAFYRQAL
CCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHC
PEHPNGMKLRASDASGNVLVERTYLSVGGGFVVTAGAPNTKVLSAAEQMTHPFRTGAELL
CCCCCCCEEEECCCCCCEEEEEEEEEECCCEEEECCCCCHHHHHHHHHHCCCHHCCCCEE
ALTESTGKSIAQLMWENERAWHTEEETRDGLLKIWAVMQSCVSRGCGIGNPEADGNLPGP
EEEHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
FQVKRRAPQLYRTLTGSPERALQDPLSMIDWINLYAIAVNEENAAGGRVVTAPTNGAAGI
HHHHHHCHHHHHHHCCCHHHHHHHHHHHHHHEEEEEEEEECCCCCCCEEEECCCCCCCHH
IPAVLHYYTRFTPGANEQGVIDFLLTAAAIGILYKLNASISGAEVGCQGEVGVACSMAAG
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCHHHHHHHH
ALAAVLGGTPHQVENAAEIGMEHNLGLTCDPVGGMVQIPCIERNAMASVKAVNAARMALR
HHHHHHCCCHHHHHHHHHCCCCCCCCEEECCCCCEEEEEEECCCHHHHHHHHHHHHHEEE
GDGSHYVSLDSVIKTMRETGADMKTKYKETSRGGLAVNIVEC
CCCCCEEEHHHHHHHHHHCCCCHHHHHHHCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]