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The map label for this gene is dinB [H]

Identifier: 161702956

GI number: 161702956

Start: 2522910

End: 2524049

Strand: Reverse

Name: dinB [H]

Synonym: Bcep18194_A5448

Alternate gene names: 161702956

Gene position: 2524049-2522910 (Counterclockwise)

Preceding gene: 78066919

Following gene: 78066912

Centisome position: 68.33

GC content: 68.95

Gene sequence:

>1140_bases
GTGAACCCGACCATCATTCCGCCTGCCGATCCGCACGTGCCGCTGCCGGGCGACGCGCTGCCGCGCATGCGCAAGATCAT
TCACTGCGACTGCGACTGCTTCTACGCGTCGGTCGAGATGCGCGACGACCCGTCGCTGCGCAACCGGCCGCTCGCGGTCG
GCGGCCGGCCCGACCAGCGTGGCGTGATCGCGACCTGTAATTACGAGGCGCGGCGCTACGGCGTGCATTCGGCGATGTCG
TCGGCGCTGGCGATGCGCAAGTGCCCGGATCTGCTGATCCTGCCGACCGCAATGGACAAATACCGCGCGGCGTCGCGGCA
GATCATGGCGATCTATCGCGACTACACGCCCGACGTCGAGCCGTTGTCGCTCGACGAGGCGTACCTCGACGTCAGCGGGT
CGGAGCGGTGCCAGGGCAGTGCGACGCTGATTGCGCGCGAGATCCGTCAGCGCGTGTTCGACACGGTCGGCGTGACCGTG
TCGGCCGGTGTCGCGCCGAACAAGTTCATCGCGAAGATCGCGTCCGACTGGAACAAGCCCGACGGGCTGTTCGTCGTGCG
GCCGCACGAGATCGACGCGTTCGTCGCGGCGCTGCCGGTGCGCAAGCTGCACGGCGTCGGCAAGGTAACGGCCACGCGGC
TCGACCGGCTCGGCATCCAGACCTGCGCGCAGTTGCGCGACTGGCCGCTGATCGACCTGCACCGCGAATTCGGCGCGTTC
GGGAAGCGGCTGTACGAACTGTCGCGCGGGATCGACGAGCGGCGCGTGCAGGCCGACCAGGGGCGCAAGTCGGTCAGCGT
CGAGACGACCTACGTGACCGACCTGACGACGCTCGAGCAGTGCGCGGAGGAAATCCGCCGCCTCGTCGTGCAACTCGACG
CGCGGATCGAACGGGCGGGCGCCGCGCGCTCGATCCGCAAGCTGTACGTGAAGATCCGCTTCGCCGATTTCCAGCGCACG
ACGGTCGAGTGCGTGGCCGATGCGACGAATGCGGACACGGCCGTCACGCTGCTCGCGAAGGGGCTGCAACGGCGTGCGCA
GGCGGTGCGGCTGCTCGGCGTCGGCGTGCGCATCGACGAGGATACGGCCGAGCGCCACGGGCAGTTCTCGCTATTCGACG
ACGCATCGCCCGCGCCATGA

Upstream 100 bases:

>100_bases
GCCGGTACGATCCGCGCAAAGCGGGCCAGTACGGCGCCGCCGGGCCCGGCCGCACGCGACAGTTGAAACCGGCACTGTGT
TTTTGTACAGTATCGGCACC

Downstream 100 bases:

>100_bases
AAAAAGGCACCGCCGAAGCGGTGCCTTTGCTTGCATGCAGCCGGAAGGGCCGGGCGGCACTCAGTGCGCGGGCGTGGCCA
TCCCGTTGTGGCGCAGCAGC

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MNPTIIPPADPHVPLPGDALPRMRKIIHCDCDCFYASVEMRDDPSLRNRPLAVGGRPDQRGVIATCNYEARRYGVHSAMS
SALAMRKCPDLLILPTAMDKYRAASRQIMAIYRDYTPDVEPLSLDEAYLDVSGSERCQGSATLIAREIRQRVFDTVGVTV
SAGVAPNKFIAKIASDWNKPDGLFVVRPHEIDAFVAALPVRKLHGVGKVTATRLDRLGIQTCAQLRDWPLIDLHREFGAF
GKRLYELSRGIDERRVQADQGRKSVSVETTYVTDLTTLEQCAEEIRRLVVQLDARIERAGAARSIRKLYVKIRFADFQRT
TVECVADATNADTAVTLLAKGLQRRAQAVRLLGVGVRIDEDTAERHGQFSLFDDASPAP

Sequences:

>Translated_379_residues
MNPTIIPPADPHVPLPGDALPRMRKIIHCDCDCFYASVEMRDDPSLRNRPLAVGGRPDQRGVIATCNYEARRYGVHSAMS
SALAMRKCPDLLILPTAMDKYRAASRQIMAIYRDYTPDVEPLSLDEAYLDVSGSERCQGSATLIAREIRQRVFDTVGVTV
SAGVAPNKFIAKIASDWNKPDGLFVVRPHEIDAFVAALPVRKLHGVGKVTATRLDRLGIQTCAQLRDWPLIDLHREFGAF
GKRLYELSRGIDERRVQADQGRKSVSVETTYVTDLTTLEQCAEEIRRLVVQLDARIERAGAARSIRKLYVKIRFADFQRT
TVECVADATNADTAVTLLAKGLQRRAQAVRLLGVGVRIDEDTAERHGQFSLFDDASPAP
>Mature_379_residues
MNPTIIPPADPHVPLPGDALPRMRKIIHCDCDCFYASVEMRDDPSLRNRPLAVGGRPDQRGVIATCNYEARRYGVHSAMS
SALAMRKCPDLLILPTAMDKYRAASRQIMAIYRDYTPDVEPLSLDEAYLDVSGSERCQGSATLIAREIRQRVFDTVGVTV
SAGVAPNKFIAKIASDWNKPDGLFVVRPHEIDAFVAALPVRKLHGVGKVTATRLDRLGIQTCAQLRDWPLIDLHREFGAF
GKRLYELSRGIDERRVQADQGRKSVSVETTYVTDLTTLEQCAEEIRRLVVQLDARIERAGAARSIRKLYVKIRFADFQRT
TVECVADATNADTAVTLLAKGLQRRAQAVRLLGVGVRIDEDTAERHGQFSLFDDASPAP

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=341, Percent_Identity=27.5659824046921, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI7706681, Length=342, Percent_Identity=27.4853801169591, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI154350220, Length=314, Percent_Identity=30.2547770700637, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI7705344, Length=107, Percent_Identity=48.5981308411215, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI5729982, Length=366, Percent_Identity=28.4153005464481, Blast_Score=110, Evalue=2e-24,
Organism=Escherichia coli, GI1786425, Length=346, Percent_Identity=48.5549132947977, Blast_Score=321, Evalue=4e-89,
Organism=Escherichia coli, GI1787432, Length=232, Percent_Identity=29.3103448275862, Blast_Score=90, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17537959, Length=293, Percent_Identity=29.3515358361775, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI193205700, Length=425, Percent_Identity=27.0588235294118, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI193205702, Length=370, Percent_Identity=26.4864864864865, Blast_Score=101, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI115534089, Length=125, Percent_Identity=38.4, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6324921, Length=206, Percent_Identity=29.126213592233, Blast_Score=77, Evalue=6e-15,
Organism=Drosophila melanogaster, GI19923006, Length=344, Percent_Identity=27.0348837209302, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI21355641, Length=290, Percent_Identity=29.3103448275862, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24644984, Length=290, Percent_Identity=29.3103448275862, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24668444, Length=238, Percent_Identity=26.4705882352941, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 42114; Mature: 42114

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPTIIPPADPHVPLPGDALPRMRKIIHCDCDCFYASVEMRDDPSLRNRPLAVGGRPDQR
CCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCEEECCCCCCC
GVIATCNYEARRYGVHSAMSSALAMRKCPDLLILPTAMDKYRAASRQIMAIYRDYTPDVE
CEEEEECCHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCC
PLSLDEAYLDVSGSERCQGSATLIAREIRQRVFDTVGVTVSAGVAPNKFIAKIASDWNKP
CCCCCHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHCCCCC
DGLFVVRPHEIDAFVAALPVRKLHGVGKVTATRLDRLGIQTCAQLRDWPLIDLHREFGAF
CCEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHH
GKRLYELSRGIDERRVQADQGRKSVSVETTYVTDLTTLEQCAEEIRRLVVQLDARIERAG
HHHHHHHHCCHHHHHHHHHCCCCEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AARSIRKLYVKIRFADFQRTTVECVADATNADTAVTLLAKGLQRRAQAVRLLGVGVRIDE
HHHHHHHHEEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEECC
DTAERHGQFSLFDDASPAP
HHHHHCCCEEEECCCCCCC
>Mature Secondary Structure
MNPTIIPPADPHVPLPGDALPRMRKIIHCDCDCFYASVEMRDDPSLRNRPLAVGGRPDQR
CCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCEEECCCCCCC
GVIATCNYEARRYGVHSAMSSALAMRKCPDLLILPTAMDKYRAASRQIMAIYRDYTPDVE
CEEEEECCHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCC
PLSLDEAYLDVSGSERCQGSATLIAREIRQRVFDTVGVTVSAGVAPNKFIAKIASDWNKP
CCCCCHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHCCCCC
DGLFVVRPHEIDAFVAALPVRKLHGVGKVTATRLDRLGIQTCAQLRDWPLIDLHREFGAF
CCEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHH
GKRLYELSRGIDERRVQADQGRKSVSVETTYVTDLTTLEQCAEEIRRLVVQLDARIERAG
HHHHHHHHCCHHHHHHHHHCCCCEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AARSIRKLYVKIRFADFQRTTVECVADATNADTAVTLLAKGLQRRAQAVRLLGVGVRIDE
HHHHHHHHEEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEECC
DTAERHGQFSLFDDASPAP
HHHHHCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]