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The map label for this gene is fes [H]

Identifier: 78066919

GI number: 78066919

Start: 2525067

End: 2526848

Strand: Reverse

Name: fes [H]

Synonym: Bcep18194_A5450

Alternate gene names: 78066919

Gene position: 2526848-2525067 (Counterclockwise)

Preceding gene: 78066920

Following gene: 161702956

Centisome position: 68.4

GC content: 72.0

Gene sequence:

>1782_bases
ATGATGACTCTCCGGAACTGGGCGATGCGCATGGCGTGTACGTGGCGTGTCGGTGTGGCGCTGGCGGCGATCGGCATGTC
GACCGCGCACGCGGAAGGCACGTTCGCGACGGGCGAGGTGGTGACGGGCAATGTCGCGCGCGAGCAGACGGCGCACGCGC
TGGCGCTCGATGCCGGTACGTTCGTCCAGGGGCGCCTCGACGGCGCGGCGGCGAATGTCGATCTCGTGACGAGCGACGGG
CACCCCCTGCGGCGACTCGTGACGGCCGATGGCCAGTCGCGCGATTTCATGTTCGTCGCGCCGGCGGACGGTGGCTATGT
GTTGCAGGTGTCGGCGCCCGAGGCCGGCGCACTGTCGGCTGACGGACGGCGAGCGTACCGGCTCGCGATCGTAAGTCGCG
TACCGCGCGCGCAGCAGCACGCACCGGTGCCCGGCATCGCGAGCCCGCGCATCGCGACGCTCGCTGTCGAACTTGCGGCG
GGCGGGTCGACCGACGCGTTCTGGCGCGAGGTGGCGGCAAGCGGCACGCCGCTCGTCGAACCGGTGCCCGCGCAGCCGGC
GCGCAGCGACGCAACGATCGCGCGCGGCCTGAACCCGCCCGACGAAGCGATGCGGCTCGTCACGTTCCTGTGGCGCGGTG
CGCGCGACAACGTGCGGCTGCTCGGCAGCCCGTCGGGCGAGCACGACACGCTGCGGCACCTGCCGGGCAGCGACGTCTGG
TACCGCAGCTACGTGGTGCCGGCCACGACGCGCATCAGCTACCTGCTCGCGCCCGACGTACCCGAACTGGATCTCGACGA
CGGTGCGCGGCGCCGCGCGATTCTCGCGACCGCGCAGCGTGATCCGCTCAATCCGCACGCGTTCATGAATCCGGCGCCCG
ATCCGTTCCAGGGCAAGTCGGTGCTCGAGTTGCGCGACGCGCCGCCGCAGCCGTGGATCGCCCCGCGCGCGAACGTGCCG
GCCGGCTCGCTGGCCGCATACCGGTTCGCCAGCACCGTGCTCGGCAATACCCGCGACGTGTACCTGTATCGACCGGCCGG
CTACCGTGCGGACGATCCGGCGCGCGCGCTCGTCGTGGTGTTCGACGCACACGCGTACGTCGACACGGTGCCGACGCCGA
CGATCCTCGACAACCTGATCGCGGAAGGGCGCGTGCCGCGCACCGCTGCACTCATCGTCGGCAATCCGGACGGCGCGACG
CGCGGCCGGGAACTGCCGCCGAATCCCGCGTTCGCGCGCTTTCTCGCGGAAGAACTGATGCCGTGGGCGCGTCGCGAGGG
CGTGAGCGCGCCGGCGGCGCGCACCGTGATCGCGGGGTCGAGCTACGGCGGGCTCGCGTCGGCCTACGCGGCGCTGCGTC
ACCCGGAGCTGTTCGGCAACGTGCTGAGCCAGTCGGGTTCGTTCTGGTGGGCACCCGCGCAGGGCGATGCACGCACGCGT
GCCGCCGGATGGCTGACGCGCGAATATGCGTCGCGCGAGCGGTTGCCCGTGCGCTTCTATCTGGAGAGCGGCCGTTTCGA
GGACGGCAAGGGGCCGGGCGGCATCGGCACGACGAGCCGCCACATGCGCGACGTGCTGCAGGCGAAAGGCTATGCGGTGC
GCTATGCGTCGACGGCGAGCGGCCACGACTACCTGCATTGGCGCGGGTCGCTCGCGTGCGGGCTGGTCGCGTTGATCGGC
ACGCCGGGACAGGGGGAGCGAGCGCCATTCGCTGCCGCGTGCCCGTTCGAGCGGCCAGTCGAACCGAGCGACGGGTCAGG
CGCGACGGCCGAAGCATCCTGA

Upstream 100 bases:

>100_bases
ACCGCACGTTCTGGGCCGGCACCTTCAACGACGGCTACGTCACGCAGAATGCGCCGCGCACCTTCAAGGTGTCGGCCACC
ATCGACTTCTGAGGCGCACG

Downstream 100 bases:

>100_bases
CTGGCCGGCGAATGCGAGGCGAACCGATTCAGCGGTGTCGTTGTACATCCATGCTGGCGCCTGCCTCGCTACTTCCCGCT
CCTGAGGCCGTTCGGTCGAG

Product: putative esterase

Products: Fe [C]

Alternate protein names: Ferric enterobactin esterase [H]

Number of amino acids: Translated: 593; Mature: 593

Protein sequence:

>593_residues
MMTLRNWAMRMACTWRVGVALAAIGMSTAHAEGTFATGEVVTGNVAREQTAHALALDAGTFVQGRLDGAAANVDLVTSDG
HPLRRLVTADGQSRDFMFVAPADGGYVLQVSAPEAGALSADGRRAYRLAIVSRVPRAQQHAPVPGIASPRIATLAVELAA
GGSTDAFWREVAASGTPLVEPVPAQPARSDATIARGLNPPDEAMRLVTFLWRGARDNVRLLGSPSGEHDTLRHLPGSDVW
YRSYVVPATTRISYLLAPDVPELDLDDGARRRAILATAQRDPLNPHAFMNPAPDPFQGKSVLELRDAPPQPWIAPRANVP
AGSLAAYRFASTVLGNTRDVYLYRPAGYRADDPARALVVVFDAHAYVDTVPTPTILDNLIAEGRVPRTAALIVGNPDGAT
RGRELPPNPAFARFLAEELMPWARREGVSAPAARTVIAGSSYGGLASAYAALRHPELFGNVLSQSGSFWWAPAQGDARTR
AAGWLTREYASRERLPVRFYLESGRFEDGKGPGGIGTTSRHMRDVLQAKGYAVRYASTASGHDYLHWRGSLACGLVALIG
TPGQGERAPFAAACPFERPVEPSDGSGATAEAS

Sequences:

>Translated_593_residues
MMTLRNWAMRMACTWRVGVALAAIGMSTAHAEGTFATGEVVTGNVAREQTAHALALDAGTFVQGRLDGAAANVDLVTSDG
HPLRRLVTADGQSRDFMFVAPADGGYVLQVSAPEAGALSADGRRAYRLAIVSRVPRAQQHAPVPGIASPRIATLAVELAA
GGSTDAFWREVAASGTPLVEPVPAQPARSDATIARGLNPPDEAMRLVTFLWRGARDNVRLLGSPSGEHDTLRHLPGSDVW
YRSYVVPATTRISYLLAPDVPELDLDDGARRRAILATAQRDPLNPHAFMNPAPDPFQGKSVLELRDAPPQPWIAPRANVP
AGSLAAYRFASTVLGNTRDVYLYRPAGYRADDPARALVVVFDAHAYVDTVPTPTILDNLIAEGRVPRTAALIVGNPDGAT
RGRELPPNPAFARFLAEELMPWARREGVSAPAARTVIAGSSYGGLASAYAALRHPELFGNVLSQSGSFWWAPAQGDARTR
AAGWLTREYASRERLPVRFYLESGRFEDGKGPGGIGTTSRHMRDVLQAKGYAVRYASTASGHDYLHWRGSLACGLVALIG
TPGQGERAPFAAACPFERPVEPSDGSGATAEAS
>Mature_593_residues
MMTLRNWAMRMACTWRVGVALAAIGMSTAHAEGTFATGEVVTGNVAREQTAHALALDAGTFVQGRLDGAAANVDLVTSDG
HPLRRLVTADGQSRDFMFVAPADGGYVLQVSAPEAGALSADGRRAYRLAIVSRVPRAQQHAPVPGIASPRIATLAVELAA
GGSTDAFWREVAASGTPLVEPVPAQPARSDATIARGLNPPDEAMRLVTFLWRGARDNVRLLGSPSGEHDTLRHLPGSDVW
YRSYVVPATTRISYLLAPDVPELDLDDGARRRAILATAQRDPLNPHAFMNPAPDPFQGKSVLELRDAPPQPWIAPRANVP
AGSLAAYRFASTVLGNTRDVYLYRPAGYRADDPARALVVVFDAHAYVDTVPTPTILDNLIAEGRVPRTAALIVGNPDGAT
RGRELPPNPAFARFLAEELMPWARREGVSAPAARTVIAGSSYGGLASAYAALRHPELFGNVLSQSGSFWWAPAQGDARTR
AAGWLTREYASRERLPVRFYLESGRFEDGKGPGGIGTTSRHMRDVLQAKGYAVRYASTASGHDYLHWRGSLACGLVALIG
TPGQGERAPFAAACPFERPVEPSDGSGATAEAS

Specific function: Upon internalization, ferric enterobactin is processed via an exquisitely specific pathway that is dependent on FES activity, making iron available for metabolic use [H]

COG id: COG2382

COG function: function code P; Enterochelin esterase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fes family [H]

Homologues:

Organism=Escherichia coli, GI1786799, Length=343, Percent_Identity=30.6122448979592, Blast_Score=119, Evalue=6e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021764
- InterPro:   IPR000801
- InterPro:   IPR014756 [H]

Pfam domain/function: PF11806 DUF3327; PF00756 Esterase [H]

EC number: NA

Molecular weight: Translated: 63157; Mature: 63157

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTLRNWAMRMACTWRVGVALAAIGMSTAHAEGTFATGEVVTGNVAREQTAHALALDAGT
CCCHHHHHHHEEEHHHHHHHHHHHCCCCCCCCCCEECCCEEECCCHHHHHHEEEEECCCC
FVQGRLDGAAANVDLVTSDGHPLRRLVTADGQSRDFMFVAPADGGYVLQVSAPEAGALSA
EEEEECCCCCCCEEEEECCCCHHHHHEECCCCCCCEEEEEECCCCEEEEECCCCCCCCCC
DGRRAYRLAIVSRVPRAQQHAPVPGIASPRIATLAVELAAGGSTDAFWREVAASGTPLVE
CCCCEEEEEHHHHCCCHHHCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHCCCCCCCC
PVPAQPARSDATIARGLNPPDEAMRLVTFLWRGARDNVRLLGSPSGEHDTLRHLPGSDVW
CCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHCCCCCCCE
YRSYVVPATTRISYLLAPDVPELDLDDGARRRAILATAQRDPLNPHAFMNPAPDPFQGKS
EEEEECCCHHEEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCE
VLELRDAPPQPWIAPRANVPAGSLAAYRFASTVLGNTRDVYLYRPAGYRADDPARALVVV
EEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCEEEEE
FDAHAYVDTVPTPTILDNLIAEGRVPRTAALIVGNPDGATRGRELPPNPAFARFLAEELM
EECCEEECCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHH
PWARREGVSAPAARTVIAGSSYGGLASAYAALRHPELFGNVLSQSGSFWWAPAQGDARTR
HHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHCHHHHHHHHHCCCCEEEECCCCCCCHH
AAGWLTREYASRERLPVRFYLESGRFEDGKGPGGIGTTSRHMRDVLQAKGYAVRYASTAS
HHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEEECCCC
GHDYLHWRGSLACGLVALIGTPGQGERAPFAAACPFERPVEPSDGSGATAEAS
CCCEEEECCCHHEEEEEEECCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MMTLRNWAMRMACTWRVGVALAAIGMSTAHAEGTFATGEVVTGNVAREQTAHALALDAGT
CCCHHHHHHHEEEHHHHHHHHHHHCCCCCCCCCCEECCCEEECCCHHHHHHEEEEECCCC
FVQGRLDGAAANVDLVTSDGHPLRRLVTADGQSRDFMFVAPADGGYVLQVSAPEAGALSA
EEEEECCCCCCCEEEEECCCCHHHHHEECCCCCCCEEEEEECCCCEEEEECCCCCCCCCC
DGRRAYRLAIVSRVPRAQQHAPVPGIASPRIATLAVELAAGGSTDAFWREVAASGTPLVE
CCCCEEEEEHHHHCCCHHHCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHCCCCCCCC
PVPAQPARSDATIARGLNPPDEAMRLVTFLWRGARDNVRLLGSPSGEHDTLRHLPGSDVW
CCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHCCCCCCCE
YRSYVVPATTRISYLLAPDVPELDLDDGARRRAILATAQRDPLNPHAFMNPAPDPFQGKS
EEEEECCCHHEEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCE
VLELRDAPPQPWIAPRANVPAGSLAAYRFASTVLGNTRDVYLYRPAGYRADDPARALVVV
EEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCEEEEE
FDAHAYVDTVPTPTILDNLIAEGRVPRTAALIVGNPDGATRGRELPPNPAFARFLAEELM
EECCEEECCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHH
PWARREGVSAPAARTVIAGSSYGGLASAYAALRHPELFGNVLSQSGSFWWAPAQGDARTR
HHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHCHHHHHHHHHCCCCEEEECCCCCCCHH
AAGWLTREYASRERLPVRFYLESGRFEDGKGPGGIGTTSRHMRDVLQAKGYAVRYASTAS
HHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEEECCCC
GHDYLHWRGSLACGLVALIGTPGQGERAPFAAACPFERPVEPSDGSGATAEAS
CCCEEEECCCHHEEEEEEECCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ferrienterobactin [C]

Specific reaction: ferrienterobactin = Fe [C]

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA