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The map label for this gene is actP [H]

Identifier: 78049828

GI number: 78049828

Start: 4904973

End: 4906700

Strand: Reverse

Name: actP [H]

Synonym: XCV4272

Alternate gene names: 78049828

Gene position: 4906700-4904973 (Counterclockwise)

Preceding gene: 78049829

Following gene: 78049826

Centisome position: 94.75

GC content: 64.7

Gene sequence:

>1728_bases
ATGAGCAAGACTTCGCGCCTTCTCCTGATCCTGGCCGGCCTGGTGCCTGCCGGCATCGCGCTGGCCGCCGGCGGCGACCT
GGGCCAGGTCGACAAGCAGCCCACCAACTGGGTGGCGATTGCCATGTTCGGCTTCTTCGTGCTGGCCACCCTGTGGATCA
CCAAATGGGCGGCGGCCAAGACCAAGTCGGCCGCCGACTTCTATACCGCTGGCGGTGGCATCACCGGTTTCCAGAACGGC
CTGGCGATCGCTGGCGACTTCATGTCGGCGGCCTCGTTCCTGGGCATCACCGCTGCGGTGATGGCCAACGGCTACGACGG
CCTGATCTATGCGATCGGTTTTCTGGTCGGCTGGCCCATCCTGACCTTCCTGATGGCCGAACGCCTGCGCAACCTCGGCA
AGTACACCTTCGCCGACGTGGCCGGTTACCGCTTCGCGCCCACAGCGATCCGCAGCTTTGCGGCGTCGGGCACCTTGGTG
GTGGTGCTGTTCTATCTGATCGCACAGATGGTCGGTGCCGGTGCGCTGATCAAGTTGCTGTTCGGCCTGGACTACTGGGT
GGCGGTGACCCTGGTCGGCGTGCTGATGATGATCTACGTGTTGTTCGGCGGCATGACCGCAACGACCTGGGTGCAGATCA
TCAAGGCCGTGCTGCTGCTGACCGGCGTGACCTTCATGGCCGTGGCGATCATGTGGCATTTCAACTTCAGCTTCGAGGCG
CTGTTTGCCGAAGGCGTGCGGGTGAAAACCGCGGTCGCGGCCAGCGGTGGCGCTTCGCCCGAGGATGCGGCAAAAGCAGG
CTTGTCGATCATGGGGCCGGGCGGTTTCGTCAAGGACCCGATTTCGGCGATTTCCTTCGGCATGGCGCTGATGTTCGGTA
CCGCCGGCCTGCCGCACATCCTGATGCGCTTCTTCACCGTTCCCGATGCCAAGCAGGCACGCAAGTCGGTGCTGTGGGCC
ACCACCTGGATCGGGTACTTCTACATCCTGATCTTCATCATCGGCTTCGGTGCGATCGCACTGGTGTTGACCAACCCGCA
GTTCGCCGATGTCGCCACCGGCACCATCCACGGCGGCAAGGGCGCGGCCAACATGGCGGCGGTGCTGGTCGGCAACGCGG
TGGGCGGCAACGTGTTCATGGGCTTCATCTCGGCGGTGGCCTTCGCCACCATCCTGGCGGTGGTGGCCGGCCTGACCCTG
TCCGGCGCCTCGGCGGTGTCGCATGACCTGTATGCCACGGTGATCAAGAAGGGCAACCCGGCGCCTGGTTCGGAGCTCAA
GGTCTCGCGTGCCACCACCCTGGTGCTGGGCGTGATCGCGGTGCTGCTGGGCATCGTGTTCGAGAAGCAGAACGTTGCCT
TCATGGTGTCGCTGGCCTTCGCCATCGCCGCCTCGGCCAACTTCCCGGTGCTGATCCTGTCGTTGCTGTGGAAGAACTGC
ACCACCCGTGGTGCAGTGACCGGTGGTTTCCTCGGCCTGATCTCCTCGCTGGTGCTGACGATCCTGTCGCCGTCGGTGTG
GGTGGACACGCTGGGCAACGCGGCCGGCTCGGCGCCGTTCCCGTACACCTCGCCGGCGCTGTTCTCGATGACGATTGGTT
TTGTCGGCATCTGGTTGTTCTCGGTGCTGGATCGCAGCCCGCAGGCAGCCAACGAACGCGCTGCCTTCAAGGCGCAGCAG
ATCCGTGCCGAAACCGGCCTGGGTGCCAGTGGCGCCTCCGGTCACTGA

Upstream 100 bases:

>100_bases
GAGTGATGGTGTTCACCATCGTCATCACCGCCATCTACGTGCGTCGCGCCAACAACACCTACGACCAGCTGACCGCGCAG
ATCCTGGAGGAAGCCCGCAA

Downstream 100 bases:

>100_bases
TCGACGGGTTGATGGTTGCTGTGATCGCAGAACGCCGGCCCAGTGCCGGCGTTCTGCGTTTTGGCGATGCCGCCGCTGTT
GGGGCGGCCCGGCCAGGAAC

Product: acetate permease

Products: NA

Alternate protein names: Acetate permease; Acetate transporter ActP [H]

Number of amino acids: Translated: 575; Mature: 574

Protein sequence:

>575_residues
MSKTSRLLLILAGLVPAGIALAAGGDLGQVDKQPTNWVAIAMFGFFVLATLWITKWAAAKTKSAADFYTAGGGITGFQNG
LAIAGDFMSAASFLGITAAVMANGYDGLIYAIGFLVGWPILTFLMAERLRNLGKYTFADVAGYRFAPTAIRSFAASGTLV
VVLFYLIAQMVGAGALIKLLFGLDYWVAVTLVGVLMMIYVLFGGMTATTWVQIIKAVLLLTGVTFMAVAIMWHFNFSFEA
LFAEGVRVKTAVAASGGASPEDAAKAGLSIMGPGGFVKDPISAISFGMALMFGTAGLPHILMRFFTVPDAKQARKSVLWA
TTWIGYFYILIFIIGFGAIALVLTNPQFADVATGTIHGGKGAANMAAVLVGNAVGGNVFMGFISAVAFATILAVVAGLTL
SGASAVSHDLYATVIKKGNPAPGSELKVSRATTLVLGVIAVLLGIVFEKQNVAFMVSLAFAIAASANFPVLILSLLWKNC
TTRGAVTGGFLGLISSLVLTILSPSVWVDTLGNAAGSAPFPYTSPALFSMTIGFVGIWLFSVLDRSPQAANERAAFKAQQ
IRAETGLGASGASGH

Sequences:

>Translated_575_residues
MSKTSRLLLILAGLVPAGIALAAGGDLGQVDKQPTNWVAIAMFGFFVLATLWITKWAAAKTKSAADFYTAGGGITGFQNG
LAIAGDFMSAASFLGITAAVMANGYDGLIYAIGFLVGWPILTFLMAERLRNLGKYTFADVAGYRFAPTAIRSFAASGTLV
VVLFYLIAQMVGAGALIKLLFGLDYWVAVTLVGVLMMIYVLFGGMTATTWVQIIKAVLLLTGVTFMAVAIMWHFNFSFEA
LFAEGVRVKTAVAASGGASPEDAAKAGLSIMGPGGFVKDPISAISFGMALMFGTAGLPHILMRFFTVPDAKQARKSVLWA
TTWIGYFYILIFIIGFGAIALVLTNPQFADVATGTIHGGKGAANMAAVLVGNAVGGNVFMGFISAVAFATILAVVAGLTL
SGASAVSHDLYATVIKKGNPAPGSELKVSRATTLVLGVIAVLLGIVFEKQNVAFMVSLAFAIAASANFPVLILSLLWKNC
TTRGAVTGGFLGLISSLVLTILSPSVWVDTLGNAAGSAPFPYTSPALFSMTIGFVGIWLFSVLDRSPQAANERAAFKAQQ
IRAETGLGASGASGH
>Mature_574_residues
SKTSRLLLILAGLVPAGIALAAGGDLGQVDKQPTNWVAIAMFGFFVLATLWITKWAAAKTKSAADFYTAGGGITGFQNGL
AIAGDFMSAASFLGITAAVMANGYDGLIYAIGFLVGWPILTFLMAERLRNLGKYTFADVAGYRFAPTAIRSFAASGTLVV
VLFYLIAQMVGAGALIKLLFGLDYWVAVTLVGVLMMIYVLFGGMTATTWVQIIKAVLLLTGVTFMAVAIMWHFNFSFEAL
FAEGVRVKTAVAASGGASPEDAAKAGLSIMGPGGFVKDPISAISFGMALMFGTAGLPHILMRFFTVPDAKQARKSVLWAT
TWIGYFYILIFIIGFGAIALVLTNPQFADVATGTIHGGKGAANMAAVLVGNAVGGNVFMGFISAVAFATILAVVAGLTLS
GASAVSHDLYATVIKKGNPAPGSELKVSRATTLVLGVIAVLLGIVFEKQNVAFMVSLAFAIAASANFPVLILSLLWKNCT
TRGAVTGGFLGLISSLVLTILSPSVWVDTLGNAAGSAPFPYTSPALFSMTIGFVGIWLFSVLDRSPQAANERAAFKAQQI
RAETGLGASGASGH

Specific function: Transports acetate [H]

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=477, Percent_Identity=23.6897274633124, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1790503, Length=571, Percent_Identity=62.8721541155867, Blast_Score=677, Evalue=0.0,
Organism=Escherichia coli, GI1787251, Length=513, Percent_Identity=23.7816764132554, Blast_Score=66, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014083
- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 59743; Mature: 59612

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: PS00456 NA_SOLUT_SYMP_1 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SKTSRLLLILAGLVPAGIALAAGGDLGQVDKQPTNWVAIAMFGFFVLATLWITKWAAAK
CCHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
TKSAADFYTAGGGITGFQNGLAIAGDFMSAASFLGITAAVMANGYDGLIYAIGFLVGWPI
CCCCCHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LTFLMAERLRNLGKYTFADVAGYRFAPTAIRSFAASGTLVVVLFYLIAQMVGAGALIKLL
HHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHH
FGLDYWVAVTLVGVLMMIYVLFGGMTATTWVQIIKAVLLLTGVTFMAVAIMWHFNFSFEA
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LFAEGVRVKTAVAASGGASPEDAAKAGLSIMGPGGFVKDPISAISFGMALMFGTAGLPHI
HHHCCCEEEEEEECCCCCCCHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHH
LMRFFTVPDAKQARKSVLWATTWIGYFYILIFIIGFGAIALVLTNPQFADVATGTIHGGK
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHCCCCCHHHCCCCCCCCCC
GAANMAAVLVGNAVGGNVFMGFISAVAFATILAVVAGLTLSGASAVSHDLYATVIKKGNP
CHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCC
APGSELKVSRATTLVLGVIAVLLGIVFEKQNVAFMVSLAFAIAASANFPVLILSLLWKNC
CCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
TTRGAVTGGFLGLISSLVLTILSPSVWVDTLGNAAGSAPFPYTSPALFSMTIGFVGIWLF
CCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
SVLDRSPQAANERAAFKAQQIRAETGLGASGASGH
HHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA