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The map label for this gene is gcp [H]

Identifier: 78049546

GI number: 78049546

Start: 4579402

End: 4580463

Strand: Reverse

Name: gcp [H]

Synonym: XCV3990

Alternate gene names: 78049546

Gene position: 4580463-4579402 (Counterclockwise)

Preceding gene: 78049553

Following gene: 78049545

Centisome position: 88.45

GC content: 70.06

Gene sequence:

>1062_bases
GTGAAAGTCCTTGGGATCGAATCATCGTGCGATGAGACCGGTGTGGCGGTCTACGACACCGCATTGTCGGGCGTGCCGGC
GCTGCGCGCCCACGCGGTGTACAGCCAGATTGCGCTGCATGCCGAATACGGCGGCGTAGTGCCCGAGCTGGCCAGCCGCG
ACCATGTGCGCAAACTGCTGCCGCTGATCCGCCAGACCCTGGGCGAAGCCGGGTTGAGGATCGACGAACTCGATGGCGTG
GCCTACACCGCCGGTCCGGGCCTGGTCGGGGCCTTGCTGGTCGGTGCCGGGGTGGCGCGTTCGCTGGCCTGGGCACTGGA
TGTGCCGGCGATCGGCGTGCATCACATGGAAGGCCACCTGCTGGCGCCGTTGATGGAGGACGACCCGCCGCAGGCGCCGT
TCGTGGCCTTGCTGGTCTCCGGCGGGCATACCCAATTGGTGTCGGTGAAGGCGCTGGGCAGCTACGAAGTGCTGGGCGAG
ACGCTGGACGACGCGGCCGGCGAAGCCTTCGACAAGACCGCCAAGATGATGGGCCTGCCGTACCCGGGCGGCCCGCAGCT
GGCGGCCTTGGCCGAAACCGGTACGCCGGGGCGCTATAAGTTCGCGCGTCCGATGACCGACCGGCCCGGCCTGGATTTCA
GTTTCAGCGGGCTCAAGACCCAGGTGCTGCTGGCCTGGCGGTCCAGCGACCAGTCCGACACCACCCGCGCGGACATCGCG
CGTGGCTTCGAAGACGCGGTGGTGGAAACCCTGGCCATCAAGTGCCTGCGCGCGCTGGACGCGGCCGGCTGCAACACCTT
GGTGGTGGCCGGCGGCGTGGGCGCAAACAAGCGCTTGCGCGCGCGCCTGCAAGAGGCCGCCCAGCGCCGCGGCGGCCGGG
TCTGCTTCCCGCGCCCGGCCTTGTGCACCGACAACGGCGCGATGATCGCCTTCGCCGGCGCGCTGCGGCTGCAGGCCGGC
GAGCATGCGGATGCGGCGGTGCATGTGACGCCGCGGTGGGATATGGCGTGCTTGCCGCCGCTGGCGGCGGCGCGGGAATC
GGGAGTGGGGAATCGGGAATAG

Upstream 100 bases:

>100_bases
GCGGCCGGCACGGCAGGGCCGAGCAGCATCTGGGAATCGGCCGATCTGCGCAGTGCAAAAGCTGCGAAAATAGTGGCATC
TCCCTGCATGCCGAGCTGCC

Downstream 100 bases:

>100_bases
TGAAGATCTTTACGCCGATCCTGTCCGTACGTGCGCTGTTGCCTTTGCTCCTCCCCATTGCCTATTCCCGACTCCCGATT
CCCCATGGATAAAGTGTTTA

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MKVLGIESSCDETGVAVYDTALSGVPALRAHAVYSQIALHAEYGGVVPELASRDHVRKLLPLIRQTLGEAGLRIDELDGV
AYTAGPGLVGALLVGAGVARSLAWALDVPAIGVHHMEGHLLAPLMEDDPPQAPFVALLVSGGHTQLVSVKALGSYEVLGE
TLDDAAGEAFDKTAKMMGLPYPGGPQLAALAETGTPGRYKFARPMTDRPGLDFSFSGLKTQVLLAWRSSDQSDTTRADIA
RGFEDAVVETLAIKCLRALDAAGCNTLVVAGGVGANKRLRARLQEAAQRRGGRVCFPRPALCTDNGAMIAFAGALRLQAG
EHADAAVHVTPRWDMACLPPLAAARESGVGNRE

Sequences:

>Translated_353_residues
MKVLGIESSCDETGVAVYDTALSGVPALRAHAVYSQIALHAEYGGVVPELASRDHVRKLLPLIRQTLGEAGLRIDELDGV
AYTAGPGLVGALLVGAGVARSLAWALDVPAIGVHHMEGHLLAPLMEDDPPQAPFVALLVSGGHTQLVSVKALGSYEVLGE
TLDDAAGEAFDKTAKMMGLPYPGGPQLAALAETGTPGRYKFARPMTDRPGLDFSFSGLKTQVLLAWRSSDQSDTTRADIA
RGFEDAVVETLAIKCLRALDAAGCNTLVVAGGVGANKRLRARLQEAAQRRGGRVCFPRPALCTDNGAMIAFAGALRLQAG
EHADAAVHVTPRWDMACLPPLAAARESGVGNRE
>Mature_353_residues
MKVLGIESSCDETGVAVYDTALSGVPALRAHAVYSQIALHAEYGGVVPELASRDHVRKLLPLIRQTLGEAGLRIDELDGV
AYTAGPGLVGALLVGAGVARSLAWALDVPAIGVHHMEGHLLAPLMEDDPPQAPFVALLVSGGHTQLVSVKALGSYEVLGE
TLDDAAGEAFDKTAKMMGLPYPGGPQLAALAETGTPGRYKFARPMTDRPGLDFSFSGLKTQVLLAWRSSDQSDTTRADIA
RGFEDAVVETLAIKCLRALDAAGCNTLVVAGGVGANKRLRARLQEAAQRRGGRVCFPRPALCTDNGAMIAFAGALRLQAG
EHADAAVHVTPRWDMACLPPLAAARESGVGNRE

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=341, Percent_Identity=32.258064516129, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI8923380, Length=295, Percent_Identity=32.5423728813559, Blast_Score=127, Evalue=2e-29,
Organism=Escherichia coli, GI1789445, Length=339, Percent_Identity=66.0766961651917, Blast_Score=451, Evalue=1e-128,
Organism=Caenorhabditis elegans, GI17557464, Length=332, Percent_Identity=29.2168674698795, Blast_Score=135, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI71995670, Length=331, Percent_Identity=32.3262839879154, Blast_Score=129, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6320099, Length=343, Percent_Identity=32.6530612244898, Blast_Score=142, Evalue=8e-35,
Organism=Saccharomyces cerevisiae, GI6322891, Length=296, Percent_Identity=29.7297297297297, Blast_Score=115, Evalue=8e-27,
Organism=Drosophila melanogaster, GI20129063, Length=343, Percent_Identity=35.2769679300292, Blast_Score=176, Evalue=1e-44,
Organism=Drosophila melanogaster, GI21357207, Length=333, Percent_Identity=31.5315315315315, Blast_Score=139, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 36928; Mature: 36928

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLGIESSCDETGVAVYDTALSGVPALRAHAVYSQIALHAEYGGVVPELASRDHVRKLL
CEEECCCCCCCCCCEEEEEHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHCHHHHHHHH
PLIRQTLGEAGLRIDELDGVAYTAGPGLVGALLVGAGVARSLAWALDVPAIGVHHMEGHL
HHHHHHHHHHCCEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCE
LAPLMEDDPPQAPFVALLVSGGHTQLVSVKALGSYEVLGETLDDAAGEAFDKTAKMMGLP
ECCCCCCCCCCCCEEEEEEECCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCC
YPGGPQLAALAETGTPGRYKFARPMTDRPGLDFSFSGLKTQVLLAWRSSDQSDTTRADIA
CCCCCCEEEEECCCCCCCEEECCCCCCCCCCCEEECCCCEEEEEEECCCCCCCHHHHHHH
RGFEDAVVETLAIKCLRALDAAGCNTLVVAGGVGANKRLRARLQEAAQRRGGRVCFPRPA
HCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCEEECCCCC
LCTDNGAMIAFAGALRLQAGEHADAAVHVTPRWDMACLPPLAAARESGVGNRE
EECCCCCEEEEEEEHEECCCCCCCEEEEECCCCCCCCCCCHHHHHHCCCCCCC
>Mature Secondary Structure
MKVLGIESSCDETGVAVYDTALSGVPALRAHAVYSQIALHAEYGGVVPELASRDHVRKLL
CEEECCCCCCCCCCEEEEEHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHCHHHHHHHH
PLIRQTLGEAGLRIDELDGVAYTAGPGLVGALLVGAGVARSLAWALDVPAIGVHHMEGHL
HHHHHHHHHHCCEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCE
LAPLMEDDPPQAPFVALLVSGGHTQLVSVKALGSYEVLGETLDDAAGEAFDKTAKMMGLP
ECCCCCCCCCCCCEEEEEEECCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCC
YPGGPQLAALAETGTPGRYKFARPMTDRPGLDFSFSGLKTQVLLAWRSSDQSDTTRADIA
CCCCCCEEEEECCCCCCCEEECCCCCCCCCCCEEECCCCEEEEEEECCCCCCCHHHHHHH
RGFEDAVVETLAIKCLRALDAAGCNTLVVAGGVGANKRLRARLQEAAQRRGGRVCFPRPA
HCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCEEECCCCC
LCTDNGAMIAFAGALRLQAGEHADAAVHVTPRWDMACLPPLAAARESGVGNRE
EECCCCCEEEEEEEHEECCCCCCCEEEEECCCCCCCCCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA