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The map label for this gene is argD [H]

Identifier: 78049100

GI number: 78049100

Start: 4060136

End: 4061362

Strand: Reverse

Name: argD [H]

Synonym: XCV3544

Alternate gene names: 78049100

Gene position: 4061362-4060136 (Counterclockwise)

Preceding gene: 78049102

Following gene: 78049098

Centisome position: 78.43

GC content: 67.89

Gene sequence:

>1227_bases
ATGAGCACCGCTGCCGATTCGCCCCTGTCCCTCGCGCACTACTACCTGCCGGTGTATCGCCCGCGCCAGGTGGTGCTGGA
GCGCGGCCAGGGCAGCCGCGTGTGGGACGATGCGGGCCGCGAGTATCTGGATCTGTCGTCGGGCATCGCGGTGAGCGGGC
TCGGCCATAACGATCCCGATCTGGTGGCTGCGCTCACCGAGCAGGCCGGCAAGCTGTGGCACACCAGTAACGTGTTTTTC
AGCGCGCCGCCGCTGAAACTGGCCGAAGAACTGGTGAGCGCCTCGCGTTTCGCGCACAAGGTGTTCCTGTGCAATTCCGG
CACCGAGGCCAACGAGGCGGCGATCAAGCTGGTGCGCAAGTGGGCCAGCAGCCAGGGCCGTCCGGCCGACAAGCGTGTCA
TCGTCACCTTCCGCGGCAGTTTTCATGGCCGTACGCTGGCATCGGTCACCGCCACTGCGCAGCCCAAGTATCAGGAAGGC
TACGAGCCGCTGCCGGGTGGATTTCGCTATGTGGATTTCAACGATGTCGCGGCGCTGGAAGCGGCGATGGCCGGCGGCGA
TGTGGCGGCGGTGATGGTCGAGCCGATCCAGGGCGAGGGCGGCGTGATGCCGGCCGCGCCGGGCTTTCTGAGCCGCGTGC
GCGCGCTGTGCGACCAGCATGATGCGCTGCTGGTGCTGGACGAAATTCAATGCGGCATGGGCCGCACCGGCACGCTGTTC
GCGCATTGGCAGGAGCAGGTGACGCCGGACATCGTGACCCTGGCCAAGGCCTTGGGTGGCGGTTTCCCGATCGGCGCGAT
GCTGGCCGGGCCCAAGGTCGCCGAAACCATGCAGTTCGGCGCGCACGGCACCACCTTCGGCGGCAACCCGCTGGCCGCGG
CAGTGGCGCGCGTGGCGCTGCGCAAGCTGGCCTCGCCGCAGATTGCCGATAACGTGGTGCGGCAATCTGCGGCATTGCGC
GCCGGGCTGGAAGCGCTCAATGCCGACTTTGGCCTGTTTGCGCAGATTCGTGGGCGTGGCCTGATGCTGGGCGCGGTACT
GGCTCCTGCGCACGCGGGGCAGGCCGGGGCGATCCTCGACCTGGCGGCCACGCATGGCTTGCTGCTGCTGCAGGCCGGCC
CGGATGTATTGCGCTTCGTGCCGGCACTCAATCTCACCGATGCCGAACTGGCCGATGGCCTGGCGCGCTTGCGTCTGGCC
ATTGCCGAGTATGTCGCCCAGGCGTGA

Upstream 100 bases:

>100_bases
TGAGTTGCGGATCGGAGAAGGGGCGCATGCGCGCATTGTGCCGCAGGCCGGCGAATGCGCGAGAATGCCGCTTCTCCCTC
CGCTTCTGCGACCCATCCTC

Downstream 100 bases:

>100_bases
TGTCGGGCGGTGCTTGCGCGCCCTCTGGCCGGCACCATGTCGGCTGGAAGGGCATTGGAGATGCGTGGTGTGTGGCATGT
AGCGCGCTGACGCAGTGCCC

Product: acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MSTAADSPLSLAHYYLPVYRPRQVVLERGQGSRVWDDAGREYLDLSSGIAVSGLGHNDPDLVAALTEQAGKLWHTSNVFF
SAPPLKLAEELVSASRFAHKVFLCNSGTEANEAAIKLVRKWASSQGRPADKRVIVTFRGSFHGRTLASVTATAQPKYQEG
YEPLPGGFRYVDFNDVAALEAAMAGGDVAAVMVEPIQGEGGVMPAAPGFLSRVRALCDQHDALLVLDEIQCGMGRTGTLF
AHWQEQVTPDIVTLAKALGGGFPIGAMLAGPKVAETMQFGAHGTTFGGNPLAAAVARVALRKLASPQIADNVVRQSAALR
AGLEALNADFGLFAQIRGRGLMLGAVLAPAHAGQAGAILDLAATHGLLLLQAGPDVLRFVPALNLTDAELADGLARLRLA
IAEYVAQA

Sequences:

>Translated_408_residues
MSTAADSPLSLAHYYLPVYRPRQVVLERGQGSRVWDDAGREYLDLSSGIAVSGLGHNDPDLVAALTEQAGKLWHTSNVFF
SAPPLKLAEELVSASRFAHKVFLCNSGTEANEAAIKLVRKWASSQGRPADKRVIVTFRGSFHGRTLASVTATAQPKYQEG
YEPLPGGFRYVDFNDVAALEAAMAGGDVAAVMVEPIQGEGGVMPAAPGFLSRVRALCDQHDALLVLDEIQCGMGRTGTLF
AHWQEQVTPDIVTLAKALGGGFPIGAMLAGPKVAETMQFGAHGTTFGGNPLAAAVARVALRKLASPQIADNVVRQSAALR
AGLEALNADFGLFAQIRGRGLMLGAVLAPAHAGQAGAILDLAATHGLLLLQAGPDVLRFVPALNLTDAELADGLARLRLA
IAEYVAQA
>Mature_407_residues
STAADSPLSLAHYYLPVYRPRQVVLERGQGSRVWDDAGREYLDLSSGIAVSGLGHNDPDLVAALTEQAGKLWHTSNVFFS
APPLKLAEELVSASRFAHKVFLCNSGTEANEAAIKLVRKWASSQGRPADKRVIVTFRGSFHGRTLASVTATAQPKYQEGY
EPLPGGFRYVDFNDVAALEAAMAGGDVAAVMVEPIQGEGGVMPAAPGFLSRVRALCDQHDALLVLDEIQCGMGRTGTLFA
HWQEQVTPDIVTLAKALGGGFPIGAMLAGPKVAETMQFGAHGTTFGGNPLAAAVARVALRKLASPQIADNVVRQSAALRA
GLEALNADFGLFAQIRGRGLMLGAVLAPAHAGQAGAILDLAATHGLLLLQAGPDVLRFVPALNLTDAELADGLARLRLAI
AEYVAQA

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=388, Percent_Identity=38.659793814433, Blast_Score=253, Evalue=2e-67,
Organism=Homo sapiens, GI284507298, Length=302, Percent_Identity=38.7417218543046, Blast_Score=200, Evalue=2e-51,
Organism=Homo sapiens, GI13994255, Length=453, Percent_Identity=28.2560706401766, Blast_Score=172, Evalue=7e-43,
Organism=Homo sapiens, GI37574042, Length=426, Percent_Identity=26.9953051643192, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI226442705, Length=426, Percent_Identity=26.2910798122066, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI226442709, Length=393, Percent_Identity=26.7175572519084, Blast_Score=122, Evalue=9e-28,
Organism=Homo sapiens, GI24119277, Length=400, Percent_Identity=27.5, Blast_Score=115, Evalue=7e-26,
Organism=Escherichia coli, GI1788044, Length=398, Percent_Identity=46.9849246231156, Blast_Score=375, Evalue=1e-105,
Organism=Escherichia coli, GI1789759, Length=390, Percent_Identity=47.9487179487179, Blast_Score=371, Evalue=1e-104,
Organism=Escherichia coli, GI145693181, Length=325, Percent_Identity=38.7692307692308, Blast_Score=212, Evalue=4e-56,
Organism=Escherichia coli, GI1789016, Length=397, Percent_Identity=34.2569269521411, Blast_Score=205, Evalue=5e-54,
Organism=Escherichia coli, GI1787560, Length=403, Percent_Identity=30.7692307692308, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1786991, Length=358, Percent_Identity=33.2402234636872, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1786349, Length=344, Percent_Identity=29.3604651162791, Blast_Score=118, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI25144271, Length=391, Percent_Identity=35.2941176470588, Blast_Score=245, Evalue=4e-65,
Organism=Caenorhabditis elegans, GI32564660, Length=439, Percent_Identity=28.7015945330296, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI25144274, Length=280, Percent_Identity=35, Blast_Score=180, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI71992977, Length=431, Percent_Identity=24.8259860788863, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17541228, Length=427, Percent_Identity=28.3372365339578, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI71981843, Length=159, Percent_Identity=33.9622641509434, Blast_Score=94, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6324432, Length=395, Percent_Identity=38.4810126582278, Blast_Score=281, Evalue=2e-76,
Organism=Saccharomyces cerevisiae, GI6323470, Length=402, Percent_Identity=33.3333333333333, Blast_Score=218, Evalue=2e-57,
Organism=Saccharomyces cerevisiae, GI6324386, Length=359, Percent_Identity=27.8551532033426, Blast_Score=102, Evalue=9e-23,
Organism=Saccharomyces cerevisiae, GI6321456, Length=362, Percent_Identity=25.414364640884, Blast_Score=94, Evalue=5e-20,
Organism=Drosophila melanogaster, GI21357415, Length=385, Percent_Identity=38.1818181818182, Blast_Score=254, Evalue=7e-68,
Organism=Drosophila melanogaster, GI28574759, Length=448, Percent_Identity=29.9107142857143, Blast_Score=185, Evalue=5e-47,
Organism=Drosophila melanogaster, GI161085790, Length=453, Percent_Identity=28.9183222958057, Blast_Score=180, Evalue=2e-45,
Organism=Drosophila melanogaster, GI21356575, Length=404, Percent_Identity=27.4752475247525, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI281366494, Length=435, Percent_Identity=24.8275862068966, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24667139, Length=435, Percent_Identity=24.8275862068966, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24667143, Length=435, Percent_Identity=24.8275862068966, Blast_Score=103, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 42861; Mature: 42729

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTAADSPLSLAHYYLPVYRPRQVVLERGQGSRVWDDAGREYLDLSSGIAVSGLGHNDPD
CCCCCCCCHHHHHHHCCCCCCHHHHHCCCCCCCCHHHHCCHHEECCCCCEEECCCCCCHH
LVAALTEQAGKLWHTSNVFFSAPPLKLAEELVSASRFAHKVFLCNSGTEANEAAIKLVRK
HHHHHHHHHCCEEECCCEEEECCCHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHH
WASSQGRPADKRVIVTFRGSFHGRTLASVTATAQPKYQEGYEPLPGGFRYVDFNDVAALE
HHCCCCCCCCCEEEEEEECCCCCCCCEEEEECCCCCHHCCCCCCCCCEEEECCCHHHHHH
AAMAGGDVAAVMVEPIQGEGGVMPAAPGFLSRVRALCDQHDALLVLDEIQCGMGRTGTLF
HHHCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECHHCCCCCCCCEE
AHWQEQVTPDIVTLAKALGGGFPIGAMLAGPKVAETMQFGAHGTTFGGNPLAAAVARVAL
EHHHHHCCHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
RKLASPQIADNVVRQSAALRAGLEALNADFGLFAQIRGRGLMLGAVLAPAHAGQAGAILD
HHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHEECCCCCEEEEHHHCCCCCCCCCCEEE
LAATHGLLLLQAGPDVLRFVPALNLTDAELADGLARLRLAIAEYVAQA
HHHHCCEEEEECCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
STAADSPLSLAHYYLPVYRPRQVVLERGQGSRVWDDAGREYLDLSSGIAVSGLGHNDPD
CCCCCCCHHHHHHHCCCCCCHHHHHCCCCCCCCHHHHCCHHEECCCCCEEECCCCCCHH
LVAALTEQAGKLWHTSNVFFSAPPLKLAEELVSASRFAHKVFLCNSGTEANEAAIKLVRK
HHHHHHHHHCCEEECCCEEEECCCHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHH
WASSQGRPADKRVIVTFRGSFHGRTLASVTATAQPKYQEGYEPLPGGFRYVDFNDVAALE
HHCCCCCCCCCEEEEEEECCCCCCCCEEEEECCCCCHHCCCCCCCCCEEEECCCHHHHHH
AAMAGGDVAAVMVEPIQGEGGVMPAAPGFLSRVRALCDQHDALLVLDEIQCGMGRTGTLF
HHHCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECHHCCCCCCCCEE
AHWQEQVTPDIVTLAKALGGGFPIGAMLAGPKVAETMQFGAHGTTFGGNPLAAAVARVAL
EHHHHHCCHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
RKLASPQIADNVVRQSAALRAGLEALNADFGLFAQIRGRGLMLGAVLAPAHAGQAGAILD
HHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHEECCCCCEEEEHHHCCCCCCCCCCEEE
LAATHGLLLLQAGPDVLRFVPALNLTDAELADGLARLRLAIAEYVAQA
HHHHCCEEEEECCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]