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The map label for this gene is creB [H]

Identifier: 162138532

GI number: 162138532

Start: 3428858

End: 3429550

Strand: Reverse

Name: creB [H]

Synonym: XCV3015

Alternate gene names: 162138532

Gene position: 3429550-3428858 (Counterclockwise)

Preceding gene: 78048582

Following gene: 78048570

Centisome position: 66.23

GC content: 69.84

Gene sequence:

>693_bases
ATGTCCGAGTCTGCCGCCCGCGTGCTCGTCGTCGAAGACGAAGCCGCCATTGCCGATACCGTGCTCTACGCACTACGCAG
CGAGGGCTATGCACCTGAGCATTGCCTGCTGGGCCGCGATGCGCTGACGCGTCTGCGCGCCGATCCGGCCGATGTGGTGG
TCCTCGATGTGGGCCTGCCGGACATCAACGGGTTCGAGGTGTGCCGCACGTTGCGCAGTTTCAGCCAGGTGCCGGTGATC
TTCCTGACCGCGCGCAACGACGAGATCGACCGCGTGCTCGGCCTGGAGCTGGGCGCCGACGATTACATGGCCAAGCCGTT
CTCGCCGCGCGAGCTGGTGGCGCGCGTGCGTGCGCGCCTGCGCCGACGCCATGCCGGCGCGCCGGCCGAATCGGGCTGGC
AGCCGCACGGCGCGTTTGCGATCGACCGCGAGGGCAGCCGCATCCGCTATGGCGAGACCCTGCTGCCGCTGACACGCTAC
GAATACGCGCTGCTGGCAGCGTTGCTGCAGCGCCCCGGTGCGATCCTGAGCCGTGCGCAGCTGATGGACCGCGGTTGGGA
CGCCAGCGCCGACAGTGCCGACCGCACCGTCGACACCCATATCAAGACGCTGCGCGGCAAGCTGCGCCTGGCCGGCGTGC
CGGCCGACCCGATCCGCACCCACCGGGGCCTTGGCTACGCGCTGGAGGTATAG

Upstream 100 bases:

>100_bases
GCGATGCCGCGAGCAATGCGGCGTGTGCGCCCGTCGTGCCACGCCATGGGGGATCACCTCGACCTGTAGGCCGTGCCCGC
ATGCCGGTATGCTGCGCGGC

Downstream 100 bases:

>100_bases
GCATGCGCCGGCACGCATTTGGTGAACTGAGCGAGGCCGCGGGCTGACATGCGGCTTGGTCTCAAGCTGTTCCTGGGCTT
CTTCCTGATCGTGGGCCTGG

Product: DNA-binding response regulator CreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MSESAARVLVVEDEAAIADTVLYALRSEGYAPEHCLLGRDALTRLRADPADVVVLDVGLPDINGFEVCRTLRSFSQVPVI
FLTARNDEIDRVLGLELGADDYMAKPFSPRELVARVRARLRRRHAGAPAESGWQPHGAFAIDREGSRIRYGETLLPLTRY
EYALLAALLQRPGAILSRAQLMDRGWDASADSADRTVDTHIKTLRGKLRLAGVPADPIRTHRGLGYALEV

Sequences:

>Translated_230_residues
MSESAARVLVVEDEAAIADTVLYALRSEGYAPEHCLLGRDALTRLRADPADVVVLDVGLPDINGFEVCRTLRSFSQVPVI
FLTARNDEIDRVLGLELGADDYMAKPFSPRELVARVRARLRRRHAGAPAESGWQPHGAFAIDREGSRIRYGETLLPLTRY
EYALLAALLQRPGAILSRAQLMDRGWDASADSADRTVDTHIKTLRGKLRLAGVPADPIRTHRGLGYALEV
>Mature_229_residues
SESAARVLVVEDEAAIADTVLYALRSEGYAPEHCLLGRDALTRLRADPADVVVLDVGLPDINGFEVCRTLRSFSQVPVIF
LTARNDEIDRVLGLELGADDYMAKPFSPRELVARVRARLRRRHAGAPAESGWQPHGAFAIDREGSRIRYGETLLPLTRYE
YALLAALLQRPGAILSRAQLMDRGWDASADSADRTVDTHIKTLRGKLRLAGVPADPIRTHRGLGYALEV

Specific function: Member of the two-component regulatory system CreC/CreB involved in catabolic regulation [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=52.914798206278, Blast_Score=220, Evalue=8e-59,
Organism=Escherichia coli, GI1788394, Length=229, Percent_Identity=38.8646288209607, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=39.1111111111111, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI87082012, Length=222, Percent_Identity=37.3873873873874, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=36.4444444444444, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1789809, Length=232, Percent_Identity=38.3620689655172, Blast_Score=123, Evalue=8e-30,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=38.2222222222222, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1790552, Length=223, Percent_Identity=35.4260089686099, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI1787229, Length=226, Percent_Identity=34.9557522123894, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1789402, Length=225, Percent_Identity=36.4444444444444, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1790863, Length=232, Percent_Identity=31.8965517241379, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI2367329, Length=182, Percent_Identity=41.2087912087912, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1787375, Length=225, Percent_Identity=31.5555555555556, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI145693140, Length=194, Percent_Identity=30.9278350515464, Blast_Score=78, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25338; Mature: 25207

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSESAARVLVVEDEAAIADTVLYALRSEGYAPEHCLLGRDALTRLRADPADVVVLDVGLP
CCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCHHHCCHHHHHHHCCCCCCEEEEECCCC
DINGFEVCRTLRSFSQVPVIFLTARNDEIDRVLGLELGADDYMAKPFSPRELVARVRARL
CCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHCEECCCHHHCCCCCHHHHHHHHHHHH
RRRHAGAPAESGWQPHGAFAIDREGSRIRYGETLLPLTRYEYALLAALLQRPGAILSRAQ
HHHHCCCCCCCCCCCCCCEEECCCCCEEECCCCCCCHHHHHHHHHHHHHHCCHHHHHHHH
LMDRGWDASADSADRTVDTHIKTLRGKLRLAGVPADPIRTHRGLGYALEV
HHHCCCCCCCCCCCHHHHHHHHHHHCCEEEECCCCCHHHHHCCCCEEECC
>Mature Secondary Structure 
SESAARVLVVEDEAAIADTVLYALRSEGYAPEHCLLGRDALTRLRADPADVVVLDVGLP
CCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCHHHCCHHHHHHHCCCCCCEEEEECCCC
DINGFEVCRTLRSFSQVPVIFLTARNDEIDRVLGLELGADDYMAKPFSPRELVARVRARL
CCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHCEECCCHHHCCCCCHHHHHHHHHHHH
RRRHAGAPAESGWQPHGAFAIDREGSRIRYGETLLPLTRYEYALLAALLQRPGAILSRAQ
HHHHCCCCCCCCCCCCCCEEECCCCCEEECCCCCCCHHHHHHHHHHHHHHCCHHHHHHHH
LMDRGWDASADSADRTVDTHIKTLRGKLRLAGVPADPIRTHRGLGYALEV
HHHCCCCCCCCCCCHHHHHHHHHHHCCEEEECCCCCHHHHHCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3531171; 7610040; 9278503 [H]