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The map label for this gene is hgdC [H]

Identifier: 78044518

GI number: 78044518

Start: 1262823

End: 1263773

Strand: Direct

Name: hgdC [H]

Synonym: CHY_1411

Alternate gene names: 78044518

Gene position: 1262823-1263773 (Clockwise)

Preceding gene: 78043931

Following gene: 78043849

Centisome position: 52.58

GC content: 42.8

Gene sequence:

>951_bases
ATGGACCTATATCTTGGAATTGATGTGGGCTCGGTAAGTACAAATCTTGTTTTAATTGATGAAGAAAATAACGTTCATGA
AAGCTTATATTTAAGGACCAGAGGACAACCAATTCGAGTAATAAAGGAAGGAATGCAAATCCTTAAAGAAAAATATGAAA
ATAAAGTAACAATAAAAGGAGTTGGTACTACAGGAAGCGGTCGCTATTTAGCCGGCGTTATCGTTGGTGCCGATATAGTT
AAAAATGAAATTACGGCTCATGCCATAGCTACCACCACTTTTGTCCCCGAGGTCCAGACAATAATTGAAATAGGCGGACA
GGACTCAAAAATAATCATCATCCGGGATGGCGTAGTAACTGATTTTGCTATGAATACCGTTTGCGCTGCTGGTACCGGTT
CTTTCTTGGACCAGCAGGCGTCCCGTTTAAATATTCCCATTGAACAGTTTGGCGAATTAGCCTTAAAATCTACCGTCCCG
GTGCGTATCGCCGGTCGCTGTACGGTATTTGCCGAATCGGATATGATCCATAAACAGCAATTAGGATACAAAATCGAAGA
TATCATCAATGGATTATGTGAAGCTTTAGTAAGAAACTACTTAAACAACGTTGGGAAAAATAAAGAAATCCTTCCTCCCA
TCGTTTTCCAGGGAGGTGTTGCCGCCAACCGTGGTATTCGGGAGGCGTTTGCCCGCGCTTTAGGGCAGGACATTATCGTA
CCAAAACATTATAATGTTATGGGAGCAATAGGAGCTGCCATTTTAGCCAGGGAAGCAACCAACGGGCAAAAAACCAACTT
TAAAGGTTTTGCCATTGCCGATTATAATTACGAAACTCGCAGCTTTGAATGCACTTACTGCCCCAACCATTGCGAAATCG
CCGAAATTTCCGAGGAAGGAAAAGTTATTGGTCGTTGGGGAGGTCGTTGCCCGCGCTGGGAGGTAATTTAG

Upstream 100 bases:

>100_bases
CGGGCAAAGCCGGAATGGAAACCCGTTTAGAAGCATTTATTGACCTTTTAAAAAGAAAAAAACTTCAAAAACTTAGCAAA
AGCTAAAGGGGGCAAGATAA

Downstream 100 bases:

>100_bases
GTAAAACCACTGTAAATTTTGCCCCCCCTTCGGGATTATTCCGGGCAAAGATTTGCCCCCCATGGGCTTCCACAATCGAT
TTCGTTATGGCCAATCCAAG

Product: CoA-substrate-specific enzyme activase domain-containing protein

Products: NA

Alternate protein names: 2-hydroxyglutaryl-CoA dehydratase component A [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MDLYLGIDVGSVSTNLVLIDEENNVHESLYLRTRGQPIRVIKEGMQILKEKYENKVTIKGVGTTGSGRYLAGVIVGADIV
KNEITAHAIATTTFVPEVQTIIEIGGQDSKIIIIRDGVVTDFAMNTVCAAGTGSFLDQQASRLNIPIEQFGELALKSTVP
VRIAGRCTVFAESDMIHKQQLGYKIEDIINGLCEALVRNYLNNVGKNKEILPPIVFQGGVAANRGIREAFARALGQDIIV
PKHYNVMGAIGAAILAREATNGQKTNFKGFAIADYNYETRSFECTYCPNHCEIAEISEEGKVIGRWGGRCPRWEVI

Sequences:

>Translated_316_residues
MDLYLGIDVGSVSTNLVLIDEENNVHESLYLRTRGQPIRVIKEGMQILKEKYENKVTIKGVGTTGSGRYLAGVIVGADIV
KNEITAHAIATTTFVPEVQTIIEIGGQDSKIIIIRDGVVTDFAMNTVCAAGTGSFLDQQASRLNIPIEQFGELALKSTVP
VRIAGRCTVFAESDMIHKQQLGYKIEDIINGLCEALVRNYLNNVGKNKEILPPIVFQGGVAANRGIREAFARALGQDIIV
PKHYNVMGAIGAAILAREATNGQKTNFKGFAIADYNYETRSFECTYCPNHCEIAEISEEGKVIGRWGGRCPRWEVI
>Mature_316_residues
MDLYLGIDVGSVSTNLVLIDEENNVHESLYLRTRGQPIRVIKEGMQILKEKYENKVTIKGVGTTGSGRYLAGVIVGADIV
KNEITAHAIATTTFVPEVQTIIEIGGQDSKIIIIRDGVVTDFAMNTVCAAGTGSFLDQQASRLNIPIEQFGELALKSTVP
VRIAGRCTVFAESDMIHKQQLGYKIEDIINGLCEALVRNYLNNVGKNKEILPPIVFQGGVAANRGIREAFARALGQDIIV
PKHYNVMGAIGAAILAREATNGQKTNFKGFAIADYNYETRSFECTYCPNHCEIAEISEEGKVIGRWGGRCPRWEVI

Specific function: Required for the activation of (R)-2-hydroxyglutaryl-CoA dehydratase. This protein is extremely sensitive towards oxygen [H]

COG id: COG1924

COG function: function code I; Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli yjiL and M.jannaschii MJ0004 and MJ0800 [H]

Homologues:

Organism=Escherichia coli, GI87082426, Length=263, Percent_Identity=33.0798479087452, Blast_Score=116, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002731
- InterPro:   IPR008275 [H]

Pfam domain/function: PF01869 BcrAD_BadFG [H]

EC number: NA

Molecular weight: Translated: 34563; Mature: 34563

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLYLGIDVGSVSTNLVLIDEENNVHESLYLRTRGQPIRVIKEGMQILKEKYENKVTIKG
CEEEEEEEECCCEEEEEEEECCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCEEEEEE
VGTTGSGRYLAGVIVGADIVKNEITAHAIATTTFVPEVQTIIEIGGQDSKIIIIRDGVVT
ECCCCCCCEEEEEEECHHHHHHHHHHHHEEEHHHHHHHHHHHHCCCCCCEEEEEECCCCH
DFAMNTVCAAGTGSFLDQQASRLNIPIEQFGELALKSTVPVRIAGRCTVFAESDMIHKQQ
HHHHHHECCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEECEEEEEECCCCHHHHH
LGYKIEDIINGLCEALVRNYLNNVGKNKEILPPIVFQGGVAANRGIREAFARALGQDIIV
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCHHHHHHHHCCCCCCC
PKHYNVMGAIGAAILAREATNGQKTNFKGFAIADYNYETRSFECTYCPNHCEIAEISEEG
CCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCEEEEEECCCCCEEEEECCCC
KVIGRWGGRCPRWEVI
CEEEECCCCCCCCCCC
>Mature Secondary Structure
MDLYLGIDVGSVSTNLVLIDEENNVHESLYLRTRGQPIRVIKEGMQILKEKYENKVTIKG
CEEEEEEEECCCEEEEEEEECCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCEEEEEE
VGTTGSGRYLAGVIVGADIVKNEITAHAIATTTFVPEVQTIIEIGGQDSKIIIIRDGVVT
ECCCCCCCEEEEEEECHHHHHHHHHHHHEEEHHHHHHHHHHHHCCCCCCEEEEEECCCCH
DFAMNTVCAAGTGSFLDQQASRLNIPIEQFGELALKSTVPVRIAGRCTVFAESDMIHKQQ
HHHHHHECCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEECEEEEEECCCCHHHHH
LGYKIEDIINGLCEALVRNYLNNVGKNKEILPPIVFQGGVAANRGIREAFARALGQDIIV
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCHHHHHHHHCCCCCCC
PKHYNVMGAIGAAILAREATNGQKTNFKGFAIADYNYETRSFECTYCPNHCEIAEISEEG
CCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCEEEEEECCCCCEEEEECCCC
KVIGRWGGRCPRWEVI
CEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8365476; 2659350; 7607244; 11106419; 11243821 [H]