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The map label for this gene is paaK1 [H]

Identifier: 78044039

GI number: 78044039

Start: 102483

End: 103799

Strand: Direct

Name: paaK1 [H]

Synonym: CHY_0120

Alternate gene names: 78044039

Gene position: 102483-103799 (Clockwise)

Preceding gene: 78045189

Following gene: 78043951

Centisome position: 4.27

GC content: 50.42

Gene sequence:

>1317_bases
TTGGGGTTTATCTGGAACAGAGAAAGAGAATGCATGTCCAGGAAGGACCTGGAAGAACTCCAGCTTGCGCGATTGAAGGC
CCAGGTGAAAAGAGCTTATGAAAAAGTCCCCTTTTATCGCGAGAAATTAGAAAAGGCCGGGATTTACCCCGAAAAAATAA
AGACGTTAAAGGATGTGCGGTATCTACCGGTAACGACCAAGGATGATCTCAGGGATAATTATCCCTTTGGTTTGTTTGCC
GAGCCCAAGAAAAATTTGGTGCGGCTTCACGCTTCCAGCGGCACCACCGGTCGGCCCACGGTGGTGGGCTATACCCGGGG
GGATCTGGAAGTCTGGGCTGAGGTGGTGGCCCGGATTGTAACCATGGCCGGTGTTACCGACGAAGATACCGCCCAGATTG
CCTTTGGCTACGGCCTTTTTACGGGAGCTTTTGGGCTTCACTATGGGTTAGAAAAAGTGGGGGCGCTGGTGGTGCCCATT
TCGGTGGGGAATTCCCGCCGGCAGATTCAGCTAATGCGTGATTTCGGTACCACCGCTTTAATTTGCACTCCCTCTTATTC
TTTGCATCTGGCGGAAACAGCCCGGGAACTGGGGATAGAGCCCAGGAGCTTGGGGCTCAAGTGGGGACTTTTTGGTTCGG
AGCCCTGGACGGAAGAAATGCGGGCGGAAATTGAAAAGCAGTGGGGAATTGTGGCAACGGACAATTATGGCTTGTCGGAA
ATTATCGGACCCGGAGTTTCGGGGGAGTGTTTGGAGCGGGAAGGACTTCACATTAACGAAGATCATTTTTTAGTAGAAGT
GGTGGACCCCGAAACCCTGGAGCCCAAAGAACCGGGAGAAGAAGGGGAGTTAATCATTACCCCTTTAACCAAAGAAGCTC
TGCCCCTTTTGCGCTACCGTACCCGGGACATCAGTAAAATTAATCCCGAGCCCTGCCGCTGTGGCCGGACTACCACCCGG
ATGCAGCGGGTAAAAGGGAGAACCGATGATATGTTAATTATCCGGGGGGTCAATGTTTTTCCCTCGCAAATTGAAAGCGT
CCTAATGGAAATTGAAGGCACAGCTCCCCATTATCAGCTCATAGTTTCCAAACGGGGATATCTGGACGAGTTAGAAGTTC
AGGTGGAAATCGAAGAAAAGTTCTTTACCGGAAAGTTTAAAGACTTGGAACAACTAACCCGCACTATAGAAGAACGTCTT
GCTTCAACTCTGCAGATTTCCGCCAAGGTAAAGCTTTTGGAACCAAGGTCCCTGGAGCGCTCCGAAGGTAAAGCCAAACG
AGTAATAGATTTAAGAAATAGCGGAGAAAGGGGATAG

Upstream 100 bases:

>100_bases
TTGTGGTTGTACCTCTGGTAAGTTTATTAGTGCCGCTAAAAGAAAGCAAGACGGTGAAACTTTTATTTGAAGAATAGCGG
GATGGAAGGGGAGGAGAACT

Downstream 100 bases:

>100_bases
AGAATGGCCAGGTTAATGACCGGAAACGAAGCGATTGCCCGGGGTGCTTTTGAAGCGGGGGTAAAAATTGGGGTGGGCTA
TCCCGGTACTCCCAGTACGG

Product: phenylacetate-coenzyme A ligase

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 438; Mature: 437

Protein sequence:

>438_residues
MGFIWNRERECMSRKDLEELQLARLKAQVKRAYEKVPFYREKLEKAGIYPEKIKTLKDVRYLPVTTKDDLRDNYPFGLFA
EPKKNLVRLHASSGTTGRPTVVGYTRGDLEVWAEVVARIVTMAGVTDEDTAQIAFGYGLFTGAFGLHYGLEKVGALVVPI
SVGNSRRQIQLMRDFGTTALICTPSYSLHLAETARELGIEPRSLGLKWGLFGSEPWTEEMRAEIEKQWGIVATDNYGLSE
IIGPGVSGECLEREGLHINEDHFLVEVVDPETLEPKEPGEEGELIITPLTKEALPLLRYRTRDISKINPEPCRCGRTTTR
MQRVKGRTDDMLIIRGVNVFPSQIESVLMEIEGTAPHYQLIVSKRGYLDELEVQVEIEEKFFTGKFKDLEQLTRTIEERL
ASTLQISAKVKLLEPRSLERSEGKAKRVIDLRNSGERG

Sequences:

>Translated_438_residues
MGFIWNRERECMSRKDLEELQLARLKAQVKRAYEKVPFYREKLEKAGIYPEKIKTLKDVRYLPVTTKDDLRDNYPFGLFA
EPKKNLVRLHASSGTTGRPTVVGYTRGDLEVWAEVVARIVTMAGVTDEDTAQIAFGYGLFTGAFGLHYGLEKVGALVVPI
SVGNSRRQIQLMRDFGTTALICTPSYSLHLAETARELGIEPRSLGLKWGLFGSEPWTEEMRAEIEKQWGIVATDNYGLSE
IIGPGVSGECLEREGLHINEDHFLVEVVDPETLEPKEPGEEGELIITPLTKEALPLLRYRTRDISKINPEPCRCGRTTTR
MQRVKGRTDDMLIIRGVNVFPSQIESVLMEIEGTAPHYQLIVSKRGYLDELEVQVEIEEKFFTGKFKDLEQLTRTIEERL
ASTLQISAKVKLLEPRSLERSEGKAKRVIDLRNSGERG
>Mature_437_residues
GFIWNRERECMSRKDLEELQLARLKAQVKRAYEKVPFYREKLEKAGIYPEKIKTLKDVRYLPVTTKDDLRDNYPFGLFAE
PKKNLVRLHASSGTTGRPTVVGYTRGDLEVWAEVVARIVTMAGVTDEDTAQIAFGYGLFTGAFGLHYGLEKVGALVVPIS
VGNSRRQIQLMRDFGTTALICTPSYSLHLAETARELGIEPRSLGLKWGLFGSEPWTEEMRAEIEKQWGIVATDNYGLSEI
IGPGVSGECLEREGLHINEDHFLVEVVDPETLEPKEPGEEGELIITPLTKEALPLLRYRTRDISKINPEPCRCGRTTTRM
QRVKGRTDDMLIIRGVNVFPSQIESVLMEIEGTAPHYQLIVSKRGYLDELEVQVEIEEKFFTGKFKDLEQLTRTIEERLA
STLQISAKVKLLEPRSLERSEGKAKRVIDLRNSGERG

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=426, Percent_Identity=51.1737089201878, Blast_Score=436, Evalue=1e-123,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 49603; Mature: 49471

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFIWNRERECMSRKDLEELQLARLKAQVKRAYEKVPFYREKLEKAGIYPEKIKTLKDVR
CCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHCE
YLPVTTKDDLRDNYPFGLFAEPKKNLVRLHASSGTTGRPTVVGYTRGDLEVWAEVVARIV
EECCCCHHHHCCCCCCCEEECCCCCEEEEECCCCCCCCCEEEEEECCCHHHHHHHHHHHH
TMAGVTDEDTAQIAFGYGLFTGAFGLHYGLEKVGALVVPISVGNSRRQIQLMRDFGTTAL
HHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCHHHHEEECCCCEEE
ICTPSYSLHLAETARELGIEPRSLGLKWGLFGSEPWTEEMRAEIEKQWGIVATDNYGLSE
EECCCCCEEHHHHHHHHCCCHHHCCEEEECCCCCCHHHHHHHHHHHHCCEEEECCCCHHH
IIGPGVSGECLEREGLHINEDHFLVEVVDPETLEPKEPGEEGELIITPLTKEALPLLRYR
HHCCCCCCHHHHCCCCEECCCCEEEEEECCCCCCCCCCCCCCCEEEECCCHHHHHHHHHH
TRDISKINPEPCRCGRTTTRMQRVKGRTDDMLIIRGVNVFPSQIESVLMEIEGTAPHYQL
HCCCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCEEE
IVSKRGYLDELEVQVEIEEKFFTGKFKDLEQLTRTIEERLASTLQISAKVKLLEPRSLER
EEECCCCCEEEEEEEEEECHHHCCCHHHHHHHHHHHHHHHHHHEEEEEEEEEECCCCCCC
SEGKAKRVIDLRNSGERG
CCCCHHEEEEECCCCCCC
>Mature Secondary Structure 
GFIWNRERECMSRKDLEELQLARLKAQVKRAYEKVPFYREKLEKAGIYPEKIKTLKDVR
CCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHCE
YLPVTTKDDLRDNYPFGLFAEPKKNLVRLHASSGTTGRPTVVGYTRGDLEVWAEVVARIV
EECCCCHHHHCCCCCCCEEECCCCCEEEEECCCCCCCCCEEEEEECCCHHHHHHHHHHHH
TMAGVTDEDTAQIAFGYGLFTGAFGLHYGLEKVGALVVPISVGNSRRQIQLMRDFGTTAL
HHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCHHHHEEECCCCEEE
ICTPSYSLHLAETARELGIEPRSLGLKWGLFGSEPWTEEMRAEIEKQWGIVATDNYGLSE
EECCCCCEEHHHHHHHHCCCHHHCCEEEECCCCCCHHHHHHHHHHHHCCEEEECCCCHHH
IIGPGVSGECLEREGLHINEDHFLVEVVDPETLEPKEPGEEGELIITPLTKEALPLLRYR
HHCCCCCCHHHHCCCCEECCCCEEEEEECCCCCCCCCCCCCCCEEEECCCHHHHHHHHHH
TRDISKINPEPCRCGRTTTRMQRVKGRTDDMLIIRGVNVFPSQIESVLMEIEGTAPHYQL
HCCCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCEEE
IVSKRGYLDELEVQVEIEEKFFTGKFKDLEQLTRTIEERLASTLQISAKVKLLEPRSLER
EEECCCCCEEEEEEEEEECHHHCCCHHHHHHHHHHHHHHHHHHEEEEEEEEEECCCCCCC
SEGKAKRVIDLRNSGERG
CCCCHHEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]