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The map label for this gene is ade2

Identifier: 78044033

GI number: 78044033

Start: 613682

End: 615394

Strand: Direct

Name: ade2

Synonym: CHY_0699

Alternate gene names: 78044033

Gene position: 613682-615394 (Clockwise)

Preceding gene: 78043497

Following gene: 78043987

Centisome position: 25.55

GC content: 47.81

Gene sequence:

>1713_bases
ATGAAACCGATAAAGGATTTGGTGGAAGTAGCGTTGGGGAAAAAGCCTGCGGACCTGGTTTTAAAAAATGCTCAAGTGTT
TAATAGCTTTACGGGAGAGTTTGTTACCGGCGATGTAGCGGTGGTGGCTGGCTACATCGCCGGCACTGGTGAATATGAAG
GAAAGACTACCTACGATTTACAGGGAGCGTATGTCACCCCGGGATTCATTGACGGGCACGTGCACATTGAAAGTTCTATG
GTGGCGCCGGCAGAGTTTGCCCGGGCGTTGGTACCGGCCGGCACCCTTACAGCCGTGGTGGATCCCCATGAAATAGCCAA
CGTTAGCGGAACTGCGGGAATTCGGTACATGCTGGAAGCAAGCAGTAATCTTCCGATAAACATTTATCTGATGCTTCCTT
CATGCGTTCCGGCAACTTCGCTGGAAACGGCCGGAGCAGTATTAACCGCCCGGGAGCTTTCGGAATTTATCAATCACCCG
CGGGTTTTAGGGTTAGGGGAGCTGATGGATTATCCTGGCGTCTTAAATACTCATGAGGAAATGCTGAAAAAATTAGCTGT
GACAGAAGGAAAGCTAATAGACGGCCATGCCCCGGGGATTTCCGGAAAAGAGCTTACTGCTTATATAGCTGCCGGTGTAA
ATTCGGAGCATGAGTGCACCACCGCTGAAGAGGCTCGGGAAAGATTATCCCGGGGGATGTACTTAATGCTCCGGGAAGGT
TCGGCGACGAAAAATTTATTGGACCTTTTACCGGCGGTAGACCGTTATACTGCTTCTCGCTGTTTCTTTGTTACCGATGA
CCGGCATCCGGAAGATTTAATTAAACTTGGTTCTATTAATCACATGGTTAAATTGGCGGTTTCGGCTGGAGCGGATTTGC
CAACGGTTTTGCAGATGGCAACCATCAATGCCGCCAATTACTTTAGACTGTACGACTTAGGTGCTATTGCTCCTGGTTAT
CGGGCTGATATTTTAGTATTTGAAGATTTACAAGAATTCAAGCCCAAGTATGTGTTTAAAGATGGTAAATTAGTAGCGGA
AAACGGAAAGCCGCTTTTTACCGGCTATCCGGTGGACGACCGGGCTGTTCGGAATACGATGCGCTTAAAAGAAATCAACC
CGGAAAAACTAAAAATACCTGCTAAATCCAACAGGGCCCGGGTCATAGGGTTAATTCCTCACCAAATTGTCACCAAAAAG
TTAGAATTAGAGGTTCCGGTGGAGGGAGGATACTTTAAAACTTCAACGGAAAAGGATATTGCCAAACTGGCAGTTTTTGA
ACGGCACAATTATACCGGTAATGTTGGGGTGGGGTTAATCCACGGCCTGGGGCTTAAAAAAGGAGCTATTGCCTCCACCG
TTGCTCATGACTCCCACAACTTGGTGGTAGCCGGAATGAGCGATGAAGATATTATTGCCGCGGTGGAGGAACTAAAGCGC
ATTGGCGGTGGGCTCACGGTTGTTGCCGATGGCCAGGTCTTGGGAAGTTTGCCGCTTCCCATTGCCGGTTTAATGTCCGA
CCGCACCCTTTATGAAGTCCAGGAAGAACTGGAGAAACTTCACCGCATAGTAAGAAACCTTGGCGTTTCTGAAAATTACG
ACCCATTTATGACCTTAGCCTTTTTAAGCCTTCCGGTGATACCGGAATTAAAACTTACGGACCTAGGTTTAGTTGATGTC
TCTACTTTTTCGGTAGTTCCCGTATCCCTGTAA

Upstream 100 bases:

>100_bases
CTTAAAGACCATGGATGAGGTGGAAGTACGCCGGAAAGCCAACGAAAGCTTAAAACGAGTAGCTGACCGGGTTGGGGTTA
GCTTAGAATAGGTGAGAGCG

Downstream 100 bases:

>100_bases
AAGGACGGTAGAGAAAAGATGGATTTACTGGATATCATAGGGCCGGTGATGATTGGGCCCTCCAGCTCCCATACTGCCGG
AGCGGTGCGGTTAGGGAGGG

Product: adenine deaminase

Products: NA

Alternate protein names: Adenase 2; Adenine aminase 2

Number of amino acids: Translated: 570; Mature: 570

Protein sequence:

>570_residues
MKPIKDLVEVALGKKPADLVLKNAQVFNSFTGEFVTGDVAVVAGYIAGTGEYEGKTTYDLQGAYVTPGFIDGHVHIESSM
VAPAEFARALVPAGTLTAVVDPHEIANVSGTAGIRYMLEASSNLPINIYLMLPSCVPATSLETAGAVLTARELSEFINHP
RVLGLGELMDYPGVLNTHEEMLKKLAVTEGKLIDGHAPGISGKELTAYIAAGVNSEHECTTAEEARERLSRGMYLMLREG
SATKNLLDLLPAVDRYTASRCFFVTDDRHPEDLIKLGSINHMVKLAVSAGADLPTVLQMATINAANYFRLYDLGAIAPGY
RADILVFEDLQEFKPKYVFKDGKLVAENGKPLFTGYPVDDRAVRNTMRLKEINPEKLKIPAKSNRARVIGLIPHQIVTKK
LELEVPVEGGYFKTSTEKDIAKLAVFERHNYTGNVGVGLIHGLGLKKGAIASTVAHDSHNLVVAGMSDEDIIAAVEELKR
IGGGLTVVADGQVLGSLPLPIAGLMSDRTLYEVQEELEKLHRIVRNLGVSENYDPFMTLAFLSLPVIPELKLTDLGLVDV
STFSVVPVSL

Sequences:

>Translated_570_residues
MKPIKDLVEVALGKKPADLVLKNAQVFNSFTGEFVTGDVAVVAGYIAGTGEYEGKTTYDLQGAYVTPGFIDGHVHIESSM
VAPAEFARALVPAGTLTAVVDPHEIANVSGTAGIRYMLEASSNLPINIYLMLPSCVPATSLETAGAVLTARELSEFINHP
RVLGLGELMDYPGVLNTHEEMLKKLAVTEGKLIDGHAPGISGKELTAYIAAGVNSEHECTTAEEARERLSRGMYLMLREG
SATKNLLDLLPAVDRYTASRCFFVTDDRHPEDLIKLGSINHMVKLAVSAGADLPTVLQMATINAANYFRLYDLGAIAPGY
RADILVFEDLQEFKPKYVFKDGKLVAENGKPLFTGYPVDDRAVRNTMRLKEINPEKLKIPAKSNRARVIGLIPHQIVTKK
LELEVPVEGGYFKTSTEKDIAKLAVFERHNYTGNVGVGLIHGLGLKKGAIASTVAHDSHNLVVAGMSDEDIIAAVEELKR
IGGGLTVVADGQVLGSLPLPIAGLMSDRTLYEVQEELEKLHRIVRNLGVSENYDPFMTLAFLSLPVIPELKLTDLGLVDV
STFSVVPVSL
>Mature_570_residues
MKPIKDLVEVALGKKPADLVLKNAQVFNSFTGEFVTGDVAVVAGYIAGTGEYEGKTTYDLQGAYVTPGFIDGHVHIESSM
VAPAEFARALVPAGTLTAVVDPHEIANVSGTAGIRYMLEASSNLPINIYLMLPSCVPATSLETAGAVLTARELSEFINHP
RVLGLGELMDYPGVLNTHEEMLKKLAVTEGKLIDGHAPGISGKELTAYIAAGVNSEHECTTAEEARERLSRGMYLMLREG
SATKNLLDLLPAVDRYTASRCFFVTDDRHPEDLIKLGSINHMVKLAVSAGADLPTVLQMATINAANYFRLYDLGAIAPGY
RADILVFEDLQEFKPKYVFKDGKLVAENGKPLFTGYPVDDRAVRNTMRLKEINPEKLKIPAKSNRARVIGLIPHQIVTKK
LELEVPVEGGYFKTSTEKDIAKLAVFERHNYTGNVGVGLIHGLGLKKGAIASTVAHDSHNLVVAGMSDEDIIAAVEELKR
IGGGLTVVADGQVLGSLPLPIAGLMSDRTLYEVQEELEKLHRIVRNLGVSENYDPFMTLAFLSLPVIPELKLTDLGLVDV
STFSVVPVSL

Specific function: Unknown

COG id: COG1001

COG function: function code F; Adenine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenine deaminase family

Homologues:

Organism=Escherichia coli, GI1790098, Length=575, Percent_Identity=37.9130434782609, Blast_Score=367, Evalue=1e-103,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ADEC2_CARHZ (Q3AE81)

Other databases:

- EMBL:   CP000141
- RefSeq:   YP_359553.1
- ProteinModelPortal:   Q3AE81
- STRING:   Q3AE81
- GeneID:   3727148
- GenomeReviews:   CP000141_GR
- KEGG:   chy:CHY_0699
- NMPDR:   fig|246194.3.peg.615
- TIGR:   CHY_0699
- eggNOG:   COG1001
- HOGENOM:   HBG725357
- OMA:   VGLGEMM
- BioCyc:   CHYD246194:CHY_0699-MONOMER
- HAMAP:   MF_01518
- InterPro:   IPR006679
- InterPro:   IPR006680
- InterPro:   IPR011059
- TIGRFAMs:   TIGR01178

Pfam domain/function: PF01979 Amidohydro_1; SSF51338 Metalo_hydrolase

EC number: =3.5.4.2

Molecular weight: Translated: 61601; Mature: 61601

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPIKDLVEVALGKKPADLVLKNAQVFNSFTGEFVTGDVAVVAGYIAGTGEYEGKTTYDL
CCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEECCHHHEEEHHCCCCCCCCCEEEEE
QGAYVTPGFIDGHVHIESSMVAPAEFARALVPAGTLTAVVDPHEIANVSGTAGIRYMLEA
CCCEECCCEEECEEEECCCCCCHHHHHHHHCCCCCEEEEECCHHHCCCCCCCCEEEEEEC
SSNLPINIYLMLPSCVPATSLETAGAVLTARELSEFINHPRVLGLGELMDYPGVLNTHEE
CCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEHHHHHCCCCCCCCHHH
MLKKLAVTEGKLIDGHAPGISGKELTAYIAAGVNSEHECTTAEEARERLSRGMYLMLREG
HHHHHHHCCCCEEECCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHCCEEEEEECC
SATKNLLDLLPAVDRYTASRCFFVTDDRHPEDLIKLGSINHMVKLAVSAGADLPTVLQMA
CCHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHCCHHHEEEEEECCCCCCHHHHHHH
TINAANYFRLYDLGAIAPGYRADILVFEDLQEFKPKYVFKDGKLVAENGKPLFTGYPVDD
EECCCCEEEEEECCCCCCCCCEEEEEEHHHHHCCCCEEEECCEEEECCCCEEEECCCCCH
RAVRNTMRLKEINPEKLKIPAKSNRARVIGLIPHQIVTKKLELEVPVEGGYFKTSTEKDI
HHHHHHHHHHCCCCCCEECCCCCCCCEEEEECCHHHHCEEEEEEECCCCCEEECCCHHHH
AKLAVFERHNYTGNVGVGLIHGLGLKKGAIASTVAHDSHNLVVAGMSDEDIIAAVEELKR
HHHHHHHCCCCCCCCCHHHHCCCCCCCCCHHHHEEECCCCEEEEECCCCHHHHHHHHHHH
IGGGLTVVADGQVLGSLPLPIAGLMSDRTLYEVQEELEKLHRIVRNLGVSENYDPFMTLA
HCCCEEEEECCCEECCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
FLSLPVIPELKLTDLGLVDVSTFSVVPVSL
HHHCCCCCCCEECCCCEEEECEEEEEEECC
>Mature Secondary Structure
MKPIKDLVEVALGKKPADLVLKNAQVFNSFTGEFVTGDVAVVAGYIAGTGEYEGKTTYDL
CCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEECCHHHEEEHHCCCCCCCCCEEEEE
QGAYVTPGFIDGHVHIESSMVAPAEFARALVPAGTLTAVVDPHEIANVSGTAGIRYMLEA
CCCEECCCEEECEEEECCCCCCHHHHHHHHCCCCCEEEEECCHHHCCCCCCCCEEEEEEC
SSNLPINIYLMLPSCVPATSLETAGAVLTARELSEFINHPRVLGLGELMDYPGVLNTHEE
CCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEHHHHHCCCCCCCCHHH
MLKKLAVTEGKLIDGHAPGISGKELTAYIAAGVNSEHECTTAEEARERLSRGMYLMLREG
HHHHHHHCCCCEEECCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHCCEEEEEECC
SATKNLLDLLPAVDRYTASRCFFVTDDRHPEDLIKLGSINHMVKLAVSAGADLPTVLQMA
CCHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHCCHHHEEEEEECCCCCCHHHHHHH
TINAANYFRLYDLGAIAPGYRADILVFEDLQEFKPKYVFKDGKLVAENGKPLFTGYPVDD
EECCCCEEEEEECCCCCCCCCEEEEEEHHHHHCCCCEEEECCEEEECCCCEEEECCCCCH
RAVRNTMRLKEINPEKLKIPAKSNRARVIGLIPHQIVTKKLELEVPVEGGYFKTSTEKDI
HHHHHHHHHHCCCCCCEECCCCCCCCEEEEECCHHHHCEEEEEEECCCCCEEECCCHHHH
AKLAVFERHNYTGNVGVGLIHGLGLKKGAIASTVAHDSHNLVVAGMSDEDIIAAVEELKR
HHHHHHHCCCCCCCCCHHHHCCCCCCCCCHHHHEEECCCCEEEEECCCCHHHHHHHHHHH
IGGGLTVVADGQVLGSLPLPIAGLMSDRTLYEVQEELEKLHRIVRNLGVSENYDPFMTLA
HCCCEEEEECCCEECCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
FLSLPVIPELKLTDLGLVDVSTFSVVPVSL
HHHCCCCCCCEECCCCEEEECEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA