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The map label for this gene is ndoA [H]

Identifier: 78043692

GI number: 78043692

Start: 633465

End: 633815

Strand: Direct

Name: ndoA [H]

Synonym: CHY_0716

Alternate gene names: 78043692

Gene position: 633465-633815 (Clockwise)

Preceding gene: 78042806

Following gene: 78043532

Centisome position: 26.38

GC content: 43.3

Gene sequence:

>351_bases
ATGGAGATCAGACGGGGAGATATTTTTTACGCGAATTTAAGCCCCGTAGTTGGTTCGGAACAGGGCGGTACCCGTCCGGT
GTTAATTTTGCAAAATGATATCGGCAATTTGTACAGCCCAACTACCATTATTGCCGCAATAACTTCCCAAATTAACAAAG
CCAAGCTGCCAACCCATGTAGAAATCTCGGCGGAGGAATCCGGGTTGGAAAAAGATTCGGTAATATTACTGGAGCAGATT
CGCACCATAGACAAAAGCCGTCTTAAAGAAAAGGTTTCTTCATTAAATAAGGAATTAATGCGGAAGGTCAATCAAGCACT
GGAAATAAGCCTCGGACTGGTGGAAATTTAG

Upstream 100 bases:

>100_bases
AAGAGATGATTAAGGGCTATAAGGAAATGGCCAAGATCAACCTGAACTTAGCTTTAGAAGGTTTTTATTACGAAGCGGAC
GGTTATATGGAGGTTAAATA

Downstream 100 bases:

>100_bases
CCTTTTTCCGGGGCTTTATTTTTTTAGGGAGGGGGCCCCATGTATATAGGAATTCCTGTCTGGCCGGAGGACGGTTTTTA
TAAAATCCGCCAGAGTTACG

Product: PemK family regulatory protein

Products: NA

Alternate protein names: Endoribonuclease EndoA; Toxin EndoA [H]

Number of amino acids: Translated: 116; Mature: 116

Protein sequence:

>116_residues
MEIRRGDIFYANLSPVVGSEQGGTRPVLILQNDIGNLYSPTTIIAAITSQINKAKLPTHVEISAEESGLEKDSVILLEQI
RTIDKSRLKEKVSSLNKELMRKVNQALEISLGLVEI

Sequences:

>Translated_116_residues
MEIRRGDIFYANLSPVVGSEQGGTRPVLILQNDIGNLYSPTTIIAAITSQINKAKLPTHVEISAEESGLEKDSVILLEQI
RTIDKSRLKEKVSSLNKELMRKVNQALEISLGLVEI
>Mature_116_residues
MEIRRGDIFYANLSPVVGSEQGGTRPVLILQNDIGNLYSPTTIIAAITSQINKAKLPTHVEISAEESGLEKDSVILLEQI
RTIDKSRLKEKVSSLNKELMRKVNQALEISLGLVEI

Specific function: Part of a toxin-antitoxin (TA) module. Has specificity for UAC sequences, yielding cleavage products with 3' phosphate and 5' hydroxyl groups. Overexpression is toxic for cell growth, probably by inhibiting protein synthesis through the cleavage of single

COG id: COG2337

COG function: function code T; Growth inhibitor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PemK/MazF family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003477
- InterPro:   IPR011067 [H]

Pfam domain/function: PF02452 PemK [H]

EC number: NA

Molecular weight: Translated: 12800; Mature: 12800

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIRRGDIFYANLSPVVGSEQGGTRPVLILQNDIGNLYSPTTIIAAITSQINKAKLPTHV
CCCCCCCEEEEECCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCEE
EISAEESGLEKDSVILLEQIRTIDKSRLKEKVSSLNKELMRKVNQALEISLGLVEI
EEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEC
>Mature Secondary Structure
MEIRRGDIFYANLSPVVGSEQGGTRPVLILQNDIGNLYSPTTIIAAITSQINKAKLPTHV
CCCCCCCEEEEECCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCEE
EISAEESGLEKDSVILLEQIRTIDKSRLKEKVSSLNKELMRKVNQALEISLGLVEI
EEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]