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The map label for this gene is recG [H]

Identifier: 77461780

GI number: 77461780

Start: 6226121

End: 6228196

Strand: Direct

Name: recG [H]

Synonym: Pfl01_5559

Alternate gene names: 77461780

Gene position: 6226121-6228196 (Clockwise)

Preceding gene: 77461779

Following gene: 77461781

Centisome position: 96.7

GC content: 66.04

Gene sequence:

>2076_bases
ATGACGGAGCTGTCGCAGGTGTCGGTCACCGCACTCAAGGGTGTCGGTGAAGCCATGGCCGAGAAACTGGCCAAGGTCGG
TCTGGAAAACCTCCAGGACGTGCTGTTCCACCTGCCGCTGCGTTATCAGGATCGCACCCGCGTGGTGCCGATCGGCGCGT
TGCGGCCGGGACAGGACGCCGTGGTCGAAGGCACCGTCAGCGGTGCCGACGTGGTCATGGGCCGGCGCCGCAGCCTCGTC
GTGCGCTTGCAGGACGGCACCGGCGGCTTGAGCCTGCGCTTCTACCATTTCAGCAACGCGCAGAAAGAAGGCCTCAAGCG
CGGCACGCGGATTCGCTGCTACGGCGAAGCCCGGCCCGGAGCCTCGGGGCTGGAGATCTACCACCCGGAATACCGCGCCA
TCAATGGCGACGAACCGCCGCCGGTGGATGAAACCCTGACCCCGGTCTACCCACTGACCGAAGGCCTGACCCAGGCGCGC
CTGCGCCAGTTGTGCATGCAGACGCTGACCCTGCTCAAGCCGGCCACCCTGCCCGACTGGTTGCCGACCGAGCTGGCCCG
CGACTACCAACTGGCGCCGCTGGCCGACGCGATCCGCTACCTGCACAACCCGCCCGCCGATGCCGACGTCGACGAACTCG
CCCTCGGCCATCACTGGGCCCAGCATCGCCTCGCTTTCGAAGAACTACTGACTCACCAGCTATCTCAGCAACGCCTGCGC
GAAAGCATGCGTTCCCTGCGTGCACCGGCGATGCCGAAAGCCACCAAGCTGCCGGCGAAATACCTGGCCAACCTCGGCTT
CAACCCGACCGGCGCGCAACAGCGGGTCGGCAACGAAATCGCCTACGACCTCAGTCAGCACGAGCCGATGCTGCGGCTGA
TTCAGGGCGACGTCGGCGCGGGCAAAACCGTGGTCGCCGCCCTCGCTGCGCTGCAAGCGCTTGAGGCGGGTTATCAGGTC
GCACTGATGGCGCCGACCGAGATCCTCGCCGAGCAGCACTTCATCACCTTCAAACGCTGGCTCGAACCGCTGGGCATCGA
CGTGGCGTGGCTGGCCGGCAAGCTCAAGGGCAAGAACCGCGTCGCCGCGCTGGAACAGATCGCCAGCGGCACGCCGATGG
TGGTCGGCACCCACGCGCTGTTCCAGGACGAAGTGCAGTTCAAGAACCTCGCGCTGGTGATCATCGACGAACAACACCGC
TTCGGCGTGCAGCAACGTCTGGCGCTGCGGCAGAAAGGCGTCGGCGGGCGCATGTGTCCGCATCAACTGATCATGACCGC
CACACCGATTCCGCGGACGCTGGCGATGAGCGCCTACGCCGACCTCGACACCTCGATCCTCGACGAACTGCCGCCCGGCC
GAACTCCGGTCAACACCGTGCTGGTCACCGACACCCGCCGCGTCGAAGTCATCGAACGGGTGCGCAGCGCCTGCGCCGAA
GGCCGTCAGGCCTACTGGGTGTGCACGCTGATCGAAGAGTCCGAAGAGCTGACCTGCCAGGCCGCCGAAACCACTTTCGA
AGACCTGACCGCCGCCCTCGGCGAGTTGAAGGTCGGGCTGATCCACGGCCGCATGAAACCTGCCGAAAAAGCCGCCGTCA
TGGCCGAATTCAAGGCCGGCAACCTGCAACTGCTGGTCGCCACCACCGTGATCGAAGTCGGCGTCGACGTACCCAACGCC
AGCCTGATGATCATCGAGAACCCTGAGCGTCTCGGCCTTGCGCAACTGCACCAGTTGCGCGGTCGTGTCGGCCGGGGCAG
CGCGGTCAGCCATTGCGTGCTGCTCTACCATCCGCCGCTGTCGCAGATCGGTCGCCAGCGCCTGGGCATCATGCGCGAGA
CCAACGACGGTTTCGTCATCGCCGAAAAAGACCTCGAACTGCGCGGCCCCGGCGAAATGCTCGGCACCCGCCAGACCGGC
CTGCTGCAATTCAAGGTCGCGGACCTTATGCGCGACGCCGATTTGTTGCCTGCCGTGCGCGATGCCGCCCAGGCCTTGCT
CGAACGCTGGCCTACCCACGTCAGCCCGTTGCTCGACCGCTGGCTGCGACACGGGCAGCAATACGGCCAAGTGTGA

Upstream 100 bases:

>100_bases
CTTCCCACGGCCGAAAGCCATCGAGATCCTCGCCGATTCCATACGCCTGTGCTCGGTCGCCAAGCCTGCCGCGCCGGTCA
CGGCCGGTTAAGCCAGCGTC

Downstream 100 bases:

>100_bases
GCACCGTCGCAGTTTCTGACAGCTCGTTCCAACCAAGCTGGTTATACTCCAGCAATTGTTTCAAAAACGGATACAGACCA
TGACCGAAGCTGCTCTCGCC

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 691; Mature: 690

Protein sequence:

>691_residues
MTELSQVSVTALKGVGEAMAEKLAKVGLENLQDVLFHLPLRYQDRTRVVPIGALRPGQDAVVEGTVSGADVVMGRRRSLV
VRLQDGTGGLSLRFYHFSNAQKEGLKRGTRIRCYGEARPGASGLEIYHPEYRAINGDEPPPVDETLTPVYPLTEGLTQAR
LRQLCMQTLTLLKPATLPDWLPTELARDYQLAPLADAIRYLHNPPADADVDELALGHHWAQHRLAFEELLTHQLSQQRLR
ESMRSLRAPAMPKATKLPAKYLANLGFNPTGAQQRVGNEIAYDLSQHEPMLRLIQGDVGAGKTVVAALAALQALEAGYQV
ALMAPTEILAEQHFITFKRWLEPLGIDVAWLAGKLKGKNRVAALEQIASGTPMVVGTHALFQDEVQFKNLALVIIDEQHR
FGVQQRLALRQKGVGGRMCPHQLIMTATPIPRTLAMSAYADLDTSILDELPPGRTPVNTVLVTDTRRVEVIERVRSACAE
GRQAYWVCTLIEESEELTCQAAETTFEDLTAALGELKVGLIHGRMKPAEKAAVMAEFKAGNLQLLVATTVIEVGVDVPNA
SLMIIENPERLGLAQLHQLRGRVGRGSAVSHCVLLYHPPLSQIGRQRLGIMRETNDGFVIAEKDLELRGPGEMLGTRQTG
LLQFKVADLMRDADLLPAVRDAAQALLERWPTHVSPLLDRWLRHGQQYGQV

Sequences:

>Translated_691_residues
MTELSQVSVTALKGVGEAMAEKLAKVGLENLQDVLFHLPLRYQDRTRVVPIGALRPGQDAVVEGTVSGADVVMGRRRSLV
VRLQDGTGGLSLRFYHFSNAQKEGLKRGTRIRCYGEARPGASGLEIYHPEYRAINGDEPPPVDETLTPVYPLTEGLTQAR
LRQLCMQTLTLLKPATLPDWLPTELARDYQLAPLADAIRYLHNPPADADVDELALGHHWAQHRLAFEELLTHQLSQQRLR
ESMRSLRAPAMPKATKLPAKYLANLGFNPTGAQQRVGNEIAYDLSQHEPMLRLIQGDVGAGKTVVAALAALQALEAGYQV
ALMAPTEILAEQHFITFKRWLEPLGIDVAWLAGKLKGKNRVAALEQIASGTPMVVGTHALFQDEVQFKNLALVIIDEQHR
FGVQQRLALRQKGVGGRMCPHQLIMTATPIPRTLAMSAYADLDTSILDELPPGRTPVNTVLVTDTRRVEVIERVRSACAE
GRQAYWVCTLIEESEELTCQAAETTFEDLTAALGELKVGLIHGRMKPAEKAAVMAEFKAGNLQLLVATTVIEVGVDVPNA
SLMIIENPERLGLAQLHQLRGRVGRGSAVSHCVLLYHPPLSQIGRQRLGIMRETNDGFVIAEKDLELRGPGEMLGTRQTG
LLQFKVADLMRDADLLPAVRDAAQALLERWPTHVSPLLDRWLRHGQQYGQV
>Mature_690_residues
TELSQVSVTALKGVGEAMAEKLAKVGLENLQDVLFHLPLRYQDRTRVVPIGALRPGQDAVVEGTVSGADVVMGRRRSLVV
RLQDGTGGLSLRFYHFSNAQKEGLKRGTRIRCYGEARPGASGLEIYHPEYRAINGDEPPPVDETLTPVYPLTEGLTQARL
RQLCMQTLTLLKPATLPDWLPTELARDYQLAPLADAIRYLHNPPADADVDELALGHHWAQHRLAFEELLTHQLSQQRLRE
SMRSLRAPAMPKATKLPAKYLANLGFNPTGAQQRVGNEIAYDLSQHEPMLRLIQGDVGAGKTVVAALAALQALEAGYQVA
LMAPTEILAEQHFITFKRWLEPLGIDVAWLAGKLKGKNRVAALEQIASGTPMVVGTHALFQDEVQFKNLALVIIDEQHRF
GVQQRLALRQKGVGGRMCPHQLIMTATPIPRTLAMSAYADLDTSILDELPPGRTPVNTVLVTDTRRVEVIERVRSACAEG
RQAYWVCTLIEESEELTCQAAETTFEDLTAALGELKVGLIHGRMKPAEKAAVMAEFKAGNLQLLVATTVIEVGVDVPNAS
LMIIENPERLGLAQLHQLRGRVGRGSAVSHCVLLYHPPLSQIGRQRLGIMRETNDGFVIAEKDLELRGPGEMLGTRQTGL
LQFKVADLMRDADLLPAVRDAAQALLERWPTHVSPLLDRWLRHGQQYGQV

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=689, Percent_Identity=59.2162554426705, Blast_Score=775, Evalue=0.0,
Organism=Escherichia coli, GI1787357, Length=389, Percent_Identity=35.4755784061697, Blast_Score=216, Evalue=5e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 76126; Mature: 75995

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTELSQVSVTALKGVGEAMAEKLAKVGLENLQDVLFHLPLRYQDRTRVVPIGALRPGQDA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCC
VVEGTVSGADVVMGRRRSLVVRLQDGTGGLSLRFYHFSNAQKEGLKRGTRIRCYGEARPG
EEECCCCCHHHHHCCCCEEEEEEECCCCCEEEEEEECCCHHHHHHCCCCEEEEEECCCCC
ASGLEIYHPEYRAINGDEPPPVDETLTPVYPLTEGLTQARLRQLCMQTLTLLKPATLPDW
CCCCEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
LPTELARDYQLAPLADAIRYLHNPPADADVDELALGHHWAQHRLAFEELLTHQLSQQRLR
CHHHHHCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESMRSLRAPAMPKATKLPAKYLANLGFNPTGAQQRVGNEIAYDLSQHEPMLRLIQGDVGA
HHHHHHCCCCCCCHHCCCHHHHHHCCCCCCCHHHHHCCHHHHHHHCCCHHHHHHHCCCCC
GKTVVAALAALQALEAGYQVALMAPTEILAEQHFITFKRWLEPLGIDVAWLAGKLKGKNR
CHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHH
VAALEQIASGTPMVVGTHALFQDEVQFKNLALVIIDEQHRFGVQQRLALRQKGVGGRMCP
HHHHHHHHCCCCEEEECHHHHHHHHHHCCEEEEEEECHHHHCHHHHHHHHHCCCCCCCCC
HQLIMTATPIPRTLAMSAYADLDTSILDELPPGRTPVNTVLVTDTRRVEVIERVRSACAE
HHHHEECCCCCHHHHHHHHHCCCHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHC
GRQAYWVCTLIEESEELTCQAAETTFEDLTAALGELKVGLIHGRMKPAEKAAVMAEFKAG
CCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHEECCC
NLQLLVATTVIEVGVDVPNASLMIIENPERLGLAQLHQLRGRVGRGSAVSHCVLLYHPPL
CEEEEEEHHHHHHCCCCCCCEEEEEECCHHCCHHHHHHHHCCCCCCCHHCEEEEEECCCH
SQIGRQRLGIMRETNDGFVIAEKDLELRGPGEMLGTRQTGLLQFKVADLMRDADLLPAVR
HHHHHHHHCCEEECCCCEEEEECCCCCCCCHHHHCCCCCCEEEEHHHHHHHCHHHHHHHH
DAAQALLERWPTHVSPLLDRWLRHGQQYGQV
HHHHHHHHHCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TELSQVSVTALKGVGEAMAEKLAKVGLENLQDVLFHLPLRYQDRTRVVPIGALRPGQDA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCC
VVEGTVSGADVVMGRRRSLVVRLQDGTGGLSLRFYHFSNAQKEGLKRGTRIRCYGEARPG
EEECCCCCHHHHHCCCCEEEEEEECCCCCEEEEEEECCCHHHHHHCCCCEEEEEECCCCC
ASGLEIYHPEYRAINGDEPPPVDETLTPVYPLTEGLTQARLRQLCMQTLTLLKPATLPDW
CCCCEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
LPTELARDYQLAPLADAIRYLHNPPADADVDELALGHHWAQHRLAFEELLTHQLSQQRLR
CHHHHHCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESMRSLRAPAMPKATKLPAKYLANLGFNPTGAQQRVGNEIAYDLSQHEPMLRLIQGDVGA
HHHHHHCCCCCCCHHCCCHHHHHHCCCCCCCHHHHHCCHHHHHHHCCCHHHHHHHCCCCC
GKTVVAALAALQALEAGYQVALMAPTEILAEQHFITFKRWLEPLGIDVAWLAGKLKGKNR
CHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHH
VAALEQIASGTPMVVGTHALFQDEVQFKNLALVIIDEQHRFGVQQRLALRQKGVGGRMCP
HHHHHHHHCCCCEEEECHHHHHHHHHHCCEEEEEEECHHHHCHHHHHHHHHCCCCCCCCC
HQLIMTATPIPRTLAMSAYADLDTSILDELPPGRTPVNTVLVTDTRRVEVIERVRSACAE
HHHHEECCCCCHHHHHHHHHCCCHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHC
GRQAYWVCTLIEESEELTCQAAETTFEDLTAALGELKVGLIHGRMKPAEKAAVMAEFKAG
CCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHEECCC
NLQLLVATTVIEVGVDVPNASLMIIENPERLGLAQLHQLRGRVGRGSAVSHCVLLYHPPL
CEEEEEEHHHHHHCCCCCCCEEEEEECCHHCCHHHHHHHHCCCCCCCHHCEEEEEECCCH
SQIGRQRLGIMRETNDGFVIAEKDLELRGPGEMLGTRQTGLLQFKVADLMRDADLLPAVR
HHHHHHHHCCEEECCCCEEEEECCCCCCCCHHHHCCCCCCEEEEHHHHHHHCHHHHHHHH
DAAQALLERWPTHVSPLLDRWLRHGQQYGQV
HHHHHHHHHCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]