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The map label for this gene is argA [H]

Identifier: 77461640

GI number: 77461640

Start: 6083858

End: 6085156

Strand: Reverse

Name: argA [H]

Synonym: Pfl01_5419

Alternate gene names: 77461640

Gene position: 6085156-6083858 (Counterclockwise)

Preceding gene: 77461641

Following gene: 77461638

Centisome position: 94.51

GC content: 63.13

Gene sequence:

>1299_bases
ATGCCCGAATACGTCAATTGGCTTCGCCACGCGTCTCCTTATATCAATGCTCACCGCGATTGCACCTTCGTCGTCATGCT
TCCGGGCGACGGCGTCGAGCATCCGAATTTCGGCAACATCGTCCATGACATCGTATTGCTGCACAGCCTCGGCGTGCGGC
TGGTGCTGGTTCACGGTTCCCGTCCTCAGATCGAAACTCGCCTTGCCGCCCGTGGCCTGACCCCGCATTACCACCACGGC
ATGCGCATCACCGATGCCGCGACGCTGGAGTGCGTGATCGATGCGGTCGGCCAGTTGCGCATCGCCATCGAAGCGCGATT
GTCGATGGACATGGCCTCGTCGCCGATGCAGGGCTCGCGTCTGCGGGTGGCCAGCGGCAACCTCGTGACGGCCCGGCCGA
TCGGCGTGCTGGAAGGTGTCGACTATCACCACACCGGCGAAGTGCGCCGGGTCGACCGCAAAGGCATCAACCGTCTGCTC
GACGAGCGCTCCATCGTGCTGCTGTCGCCGCTGGGTTATTCGCCGACCGGCGAGATCTTCAACCTGGCCTGCGAAGACGT
CGCCACCCGTGCCGCCATCGATCTGGGCGCCGACAAGCTGCTGCTGTTCGGCGCCGACCTCGGTCTGATCGACGAAAACG
GCAAACTGGTGCGCGAACTGCGTCCGCAACAGGTGCCGGCACATCTGCAGCGTCTGGGCAGCAACTATCAGGCGGAACTG
CTGGATGCCGCCGCCGAAGCCTGTCGTGGCGGCGTGGCACGCAGCCATATCGTCAGTTATGCCGAGGATGGTGCGCTGCT
GACCGAACTGTTCACCCGTGACGGTGGCGGTACGCTGGTGGCCCAGGAGCAATTCGAACTGGTGCGCGAGGCGGCGATTG
AAGACGTCGGTGGCTTGCTTGACCTGATCAGTCCGCTGGAAGAGCAGGGGATTCTGGTGCGTCGCTCGCGCGAAGTGCTG
GAGCGTGAGATCGAGCAGTTCAGTGTGGTCGAGCGTGAAGGGATGATCATCGCCTGTGCGGCGCTGTATCAGATTGCCGA
TTCGGATGCCGGTGAACTGGCGTGCCTGGCGGTGAATCCCGAGTATCGCCATGGCGGTCGCGGCGACGAATTGCTCGAGC
GCATCGAGACCCGTGCCCGGGCGCAGGGCCTGAAGACTTTGTTCGTCCTCACCACCCGCACTGCCCACTGGTTCCGCGAG
CGCGGTTTCGAGCCGAGCAGCGTTGAACGCCTGCCGGCGGCGCGGGCTTCTCTCTATAACTATCAGCGCAATTCAAAGAT
CTTCGAAAAGTCTCTGTGA

Upstream 100 bases:

>100_bases
CGCGCGTGTCGCCAAGCCTGTTCCGACGATAACCATCAGCCCGCTGTGCGTTTTCCGTTCTGCCCTTTTTCCGGCTGCTA
TTTATTACAGGCCCAGGTTC

Downstream 100 bases:

>100_bases
TATGCGATTGCCCCCACGGGATGCGTGGGGGCAATTTGTTTACTCCGCTACAAACTTCGCACTGACGTACGGCGAGTAGT
CAGGCAAAACGCTTTCGACC

Product: N-acetylglutamate synthase

Products: NA

Alternate protein names: N-acetylglutamate synthase; AGS; NAGS [H]

Number of amino acids: Translated: 432; Mature: 431

Protein sequence:

>432_residues
MPEYVNWLRHASPYINAHRDCTFVVMLPGDGVEHPNFGNIVHDIVLLHSLGVRLVLVHGSRPQIETRLAARGLTPHYHHG
MRITDAATLECVIDAVGQLRIAIEARLSMDMASSPMQGSRLRVASGNLVTARPIGVLEGVDYHHTGEVRRVDRKGINRLL
DERSIVLLSPLGYSPTGEIFNLACEDVATRAAIDLGADKLLLFGADLGLIDENGKLVRELRPQQVPAHLQRLGSNYQAEL
LDAAAEACRGGVARSHIVSYAEDGALLTELFTRDGGGTLVAQEQFELVREAAIEDVGGLLDLISPLEEQGILVRRSREVL
EREIEQFSVVEREGMIIACAALYQIADSDAGELACLAVNPEYRHGGRGDELLERIETRARAQGLKTLFVLTTRTAHWFRE
RGFEPSSVERLPAARASLYNYQRNSKIFEKSL

Sequences:

>Translated_432_residues
MPEYVNWLRHASPYINAHRDCTFVVMLPGDGVEHPNFGNIVHDIVLLHSLGVRLVLVHGSRPQIETRLAARGLTPHYHHG
MRITDAATLECVIDAVGQLRIAIEARLSMDMASSPMQGSRLRVASGNLVTARPIGVLEGVDYHHTGEVRRVDRKGINRLL
DERSIVLLSPLGYSPTGEIFNLACEDVATRAAIDLGADKLLLFGADLGLIDENGKLVRELRPQQVPAHLQRLGSNYQAEL
LDAAAEACRGGVARSHIVSYAEDGALLTELFTRDGGGTLVAQEQFELVREAAIEDVGGLLDLISPLEEQGILVRRSREVL
EREIEQFSVVEREGMIIACAALYQIADSDAGELACLAVNPEYRHGGRGDELLERIETRARAQGLKTLFVLTTRTAHWFRE
RGFEPSSVERLPAARASLYNYQRNSKIFEKSL
>Mature_431_residues
PEYVNWLRHASPYINAHRDCTFVVMLPGDGVEHPNFGNIVHDIVLLHSLGVRLVLVHGSRPQIETRLAARGLTPHYHHGM
RITDAATLECVIDAVGQLRIAIEARLSMDMASSPMQGSRLRVASGNLVTARPIGVLEGVDYHHTGEVRRVDRKGINRLLD
ERSIVLLSPLGYSPTGEIFNLACEDVATRAAIDLGADKLLLFGADLGLIDENGKLVRELRPQQVPAHLQRLGSNYQAELL
DAAAEACRGGVARSHIVSYAEDGALLTELFTRDGGGTLVAQEQFELVREAAIEDVGGLLDLISPLEEQGILVRRSREVLE
REIEQFSVVEREGMIIACAALYQIADSDAGELACLAVNPEYRHGGRGDELLERIETRARAQGLKTLFVLTTRTAHWFRER
GFEPSSVERLPAARASLYNYQRNSKIFEKSL

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI1789181, Length=435, Percent_Identity=51.0344827586207, Blast_Score=457, Evalue=1e-130,
Organism=Saccharomyces cerevisiae, GI6320913, Length=294, Percent_Identity=23.1292517006803, Blast_Score=67, Evalue=7e-12,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR001048
- InterPro:   IPR010167 [H]

Pfam domain/function: PF00696 AA_kinase; PF00583 Acetyltransf_1 [H]

EC number: =2.3.1.1 [H]

Molecular weight: Translated: 47698; Mature: 47567

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEYVNWLRHASPYINAHRDCTFVVMLPGDGVEHPNFGNIVHDIVLLHSLGVRLVLVHGS
CCHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCEEEEEEECC
RPQIETRLAARGLTPHYHHGMRITDAATLECVIDAVGQLRIAIEARLSMDMASSPMQGSR
CCCHHHHHHHCCCCCCHHCCEEEECHHHHHHHHHHHHHEEEEEEHHHHHHHCCCCCCCCE
LRVASGNLVTARPIGVLEGVDYHHTGEVRRVDRKGINRLLDERSIVLLSPLGYSPTGEIF
EEEECCCEEEECCCHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHH
NLACEDVATRAAIDLGADKLLLFGADLGLIDENGKLVRELRPQQVPAHLQRLGSNYQAEL
HHHHHHHHHHHHHHCCCCEEEEEECCCCEECCCCHHHHHCCCCHHHHHHHHHCCCHHHHH
LDAAAEACRGGVARSHIVSYAEDGALLTELFTRDGGGTLVAQEQFELVREAAIEDVGGLL
HHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHH
DLISPLEEQGILVRRSREVLEREIEQFSVVEREGMIIACAALYQIADSDAGELACLAVNP
HHHHHHHHCCEEHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHCCCCCCEEEEEECC
EYRHGGRGDELLERIETRARAQGLKTLFVLTTRTAHWFRERGFEPSSVERLPAARASLYN
CCCCCCCHHHHHHHHHHHHHHHCCEEEEEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
YQRNSKIFEKSL
HHHCCCHHHHCC
>Mature Secondary Structure 
PEYVNWLRHASPYINAHRDCTFVVMLPGDGVEHPNFGNIVHDIVLLHSLGVRLVLVHGS
CHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCEEEEEEECC
RPQIETRLAARGLTPHYHHGMRITDAATLECVIDAVGQLRIAIEARLSMDMASSPMQGSR
CCCHHHHHHHCCCCCCHHCCEEEECHHHHHHHHHHHHHEEEEEEHHHHHHHCCCCCCCCE
LRVASGNLVTARPIGVLEGVDYHHTGEVRRVDRKGINRLLDERSIVLLSPLGYSPTGEIF
EEEECCCEEEECCCHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHH
NLACEDVATRAAIDLGADKLLLFGADLGLIDENGKLVRELRPQQVPAHLQRLGSNYQAEL
HHHHHHHHHHHHHHCCCCEEEEEECCCCEECCCCHHHHHCCCCHHHHHHHHHCCCHHHHH
LDAAAEACRGGVARSHIVSYAEDGALLTELFTRDGGGTLVAQEQFELVREAAIEDVGGLL
HHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHH
DLISPLEEQGILVRRSREVLEREIEQFSVVEREGMIIACAALYQIADSDAGELACLAVNP
HHHHHHHHCCEEHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHCCCCCCEEEEEECC
EYRHGGRGDELLERIETRARAQGLKTLFVLTTRTAHWFRERGFEPSSVERLPAARASLYN
CCCCCCCHHHHHHHHHHHHHHHCCEEEEEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
YQRNSKIFEKSL
HHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA