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The map label for this gene is argE [H]

Identifier: 77461641

GI number: 77461641

Start: 6085292

End: 6086440

Strand: Reverse

Name: argE [H]

Synonym: Pfl01_5420

Alternate gene names: 77461641

Gene position: 6086440-6085292 (Counterclockwise)

Preceding gene: 77461643

Following gene: 77461640

Centisome position: 94.53

GC content: 63.27

Gene sequence:

>1149_bases
ATGCCTTTGCCGTCCATGCAAGACCAGTTCGCTGCACTGATCGCAGCGCCGTCGGTCAGCTGCACCCAGCCGGGCCTCGA
CCAGTCCAACCGGGCGGTGATCGATCTGCTTGCGGGCTGGCTCGGCGACCTCGGCTTCAGCTGCGACATCCAGCAGGTCA
GTCCCGGCAAATTCAATCTGCTCGCCAGTTTCGGCAGTGGCCCCGGCGGGCTGGTGCTGGCCGGGCACAGCGACACGGTG
CCCTACGACGATGCGTTGTGGAAAACCGATCCGCTGAAACTCACCGAAGTCGATGGCCGCTGGGTCGGTCTCGGCAGTTG
CGACATGAAGGGCTTCTTCGCCCTGATCATCGAAGCCGTGCAACCGCTGCTCGCTCAACCGTTCAAGCAGCCGCTGCTGA
TCCTCGCCACCTGCGATGAAGAAAGCTCGATGTCCGGTGCCCGGGCGCTGGCCGAAGCGGGGCGCCCGCTGGGCCGGGCG
GCCGTGATCGGCGAGCCGACCGGGCTCAAGCCGATCCGCATGCACAAGGGCATCATGATGGAGCGCATCGATATCCTCGG
GCAGAGCGGCCATTCGTCGGATCCGCGCCTGGGGCACAGCGCCCTCGAAGCGATGCACGATGCCATCGGCGAACTGCGCG
GCCTGCGCCTGTTGTGGCAGCGTGAATTCAACAACCCGCAGTTCAGCGTGCCGCAGCCGACCATGAACTTCGGCTGTATC
CACGGTGGCGACAACCCCAACCGTATCTGCGGCCAGTGTTCACTGGAGTTCGACCTGCGGCCGTTGCCGGGGATGGACCC
GAAAATCTTGCGCAGCGAGATTCTGCGCAAGCTCAACCCGGTCGCCGAACGGCATAAAGTGAAGATCGATTACGCGCCGC
TGTTTCCCGAAGTGCCGCCGTTCGAGCAGGCCGAAGACGCGGAGCTGGTGCGAATTGCCGAAAAACTCACCGGCCACACG
GCCGAAGCGGTAGCGTTCGGCACCGAAGCGCCTTATCTTCAGCGCCTTGGCTGCGAAACCATCGTGCTCGGCCCCGGCGA
CATCGCCTGTGCGCACCAGCCGGACGAGTACCTCGAAATGTCACGTTTGCAGCCTACCGTGCATCTATTGCGGCAGTTGA
TCGAACATTACTGTCTCAAAACTGTATAA

Upstream 100 bases:

>100_bases
GTGCAGTGTACAGGACTGAACCTTCCTACGCTTTGCGGCGGTTTATTCTCGGCGCCGGATGGTTCTATGATGAACCTCAA
TCCGGGAGTTGGAGTCAGCG

Downstream 100 bases:

>100_bases
ATTGCCCATACACCCACCCGTATTCATGAGGAGAGCGCGCGTGTCGCCAAGCCTGTTCCGACGATAACCATCAGCCCGCT
GTGCGTTTTCCGTTCTGCCC

Product: acetylornithine deacetylase

Products: NA

Alternate protein names: AO; Acetylornithinase; N-acetylornithinase; NAO [H]

Number of amino acids: Translated: 382; Mature: 381

Protein sequence:

>382_residues
MPLPSMQDQFAALIAAPSVSCTQPGLDQSNRAVIDLLAGWLGDLGFSCDIQQVSPGKFNLLASFGSGPGGLVLAGHSDTV
PYDDALWKTDPLKLTEVDGRWVGLGSCDMKGFFALIIEAVQPLLAQPFKQPLLILATCDEESSMSGARALAEAGRPLGRA
AVIGEPTGLKPIRMHKGIMMERIDILGQSGHSSDPRLGHSALEAMHDAIGELRGLRLLWQREFNNPQFSVPQPTMNFGCI
HGGDNPNRICGQCSLEFDLRPLPGMDPKILRSEILRKLNPVAERHKVKIDYAPLFPEVPPFEQAEDAELVRIAEKLTGHT
AEAVAFGTEAPYLQRLGCETIVLGPGDIACAHQPDEYLEMSRLQPTVHLLRQLIEHYCLKTV

Sequences:

>Translated_382_residues
MPLPSMQDQFAALIAAPSVSCTQPGLDQSNRAVIDLLAGWLGDLGFSCDIQQVSPGKFNLLASFGSGPGGLVLAGHSDTV
PYDDALWKTDPLKLTEVDGRWVGLGSCDMKGFFALIIEAVQPLLAQPFKQPLLILATCDEESSMSGARALAEAGRPLGRA
AVIGEPTGLKPIRMHKGIMMERIDILGQSGHSSDPRLGHSALEAMHDAIGELRGLRLLWQREFNNPQFSVPQPTMNFGCI
HGGDNPNRICGQCSLEFDLRPLPGMDPKILRSEILRKLNPVAERHKVKIDYAPLFPEVPPFEQAEDAELVRIAEKLTGHT
AEAVAFGTEAPYLQRLGCETIVLGPGDIACAHQPDEYLEMSRLQPTVHLLRQLIEHYCLKTV
>Mature_381_residues
PLPSMQDQFAALIAAPSVSCTQPGLDQSNRAVIDLLAGWLGDLGFSCDIQQVSPGKFNLLASFGSGPGGLVLAGHSDTVP
YDDALWKTDPLKLTEVDGRWVGLGSCDMKGFFALIIEAVQPLLAQPFKQPLLILATCDEESSMSGARALAEAGRPLGRAA
VIGEPTGLKPIRMHKGIMMERIDILGQSGHSSDPRLGHSALEAMHDAIGELRGLRLLWQREFNNPQFSVPQPTMNFGCIH
GGDNPNRICGQCSLEFDLRPLPGMDPKILRSEILRKLNPVAERHKVKIDYAPLFPEVPPFEQAEDAELVRIAEKLTGHTA
EAVAFGTEAPYLQRLGCETIVLGPGDIACAHQPDEYLEMSRLQPTVHLLRQLIEHYCLKTV

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. ArgE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=378, Percent_Identity=50.5291005291005, Blast_Score=369, Evalue=1e-103,
Organism=Escherichia coli, GI1788816, Length=389, Percent_Identity=23.9074550128535, Blast_Score=79, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17551016, Length=360, Percent_Identity=25.2777777777778, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010169
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.16 [H]

Molecular weight: Translated: 41592; Mature: 41461

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS00759 ARGE_DAPE_CPG2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLPSMQDQFAALIAAPSVSCTQPGLDQSNRAVIDLLAGWLGDLGFSCDIQQVSPGKFNL
CCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEE
LASFGSGPGGLVLAGHSDTVPYDDALWKTDPLKLTEVDGRWVGLGSCDMKGFFALIIEAV
EEECCCCCCCEEEECCCCCCCCCCCCCCCCCEEEEECCCCEEECCCCCHHHHHHHHHHHH
QPLLAQPFKQPLLILATCDEESSMSGARALAEAGRPLGRAAVIGEPTGLKPIRMHKGIMM
HHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHH
ERIDILGQSGHSSDPRLGHSALEAMHDAIGELRGLRLLWQREFNNPQFSVPQPTMNFGCI
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEE
HGGDNPNRICGQCSLEFDLRPLPGMDPKILRSEILRKLNPVAERHKVKIDYAPLFPEVPP
ECCCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHCHHHHHHEEEEEECCCCCCCCC
FEQAEDAELVRIAEKLTGHTAEAVAFGTEAPYLQRLGCETIVLGPGDIACAHQPDEYLEM
CCCCCCHHHHHHHHHHCCCCHHHEEECCCCHHHHHCCCCEEEECCCCEEECCCCHHHHHH
SRLQPTVHLLRQLIEHYCLKTV
HHCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PLPSMQDQFAALIAAPSVSCTQPGLDQSNRAVIDLLAGWLGDLGFSCDIQQVSPGKFNL
CCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEE
LASFGSGPGGLVLAGHSDTVPYDDALWKTDPLKLTEVDGRWVGLGSCDMKGFFALIIEAV
EEECCCCCCCEEEECCCCCCCCCCCCCCCCCEEEEECCCCEEECCCCCHHHHHHHHHHHH
QPLLAQPFKQPLLILATCDEESSMSGARALAEAGRPLGRAAVIGEPTGLKPIRMHKGIMM
HHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHH
ERIDILGQSGHSSDPRLGHSALEAMHDAIGELRGLRLLWQREFNNPQFSVPQPTMNFGCI
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEE
HGGDNPNRICGQCSLEFDLRPLPGMDPKILRSEILRKLNPVAERHKVKIDYAPLFPEVPP
ECCCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHCHHHHHHEEEEEECCCCCCCCC
FEQAEDAELVRIAEKLTGHTAEAVAFGTEAPYLQRLGCETIVLGPGDIACAHQPDEYLEM
CCCCCCHHHHHHHHHHCCCCHHHEEECCCCHHHHHCCCCEEEECCCCEEECCCCHHHHHH
SRLQPTVHLLRQLIEHYCLKTV
HHCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA