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The map label for this gene is quiP [H]

Identifier: 77461619

GI number: 77461619

Start: 6059650

End: 6062061

Strand: Direct

Name: quiP [H]

Synonym: Pfl01_5398

Alternate gene names: 77461619

Gene position: 6059650-6062061 (Clockwise)

Preceding gene: 77461615

Following gene: 77461621

Centisome position: 94.12

GC content: 64.39

Gene sequence:

>2412_bases
ATGAAAAAAGGCCTGACCGTACTTGCGTTGCTGATCGTCATTCCCGCCATCGGGGTCGGCGGTTACCTCTACAGCAAGCA
ACCGACGCGTCAGGGCCAGGTGGAGTTACGCAACCTGCAAGGCTCGGTGACCGTGCGTTACGACGAGCGCGGAGTGCCGC
ACATCCGGGCCGAAAACGAGATCGACCTCTACCGCGCCCTCGGCTATGTGCACGCCCAGGACCGACTGTTCCAGATGGAG
GCCATGCGCCGTCTCGCCCGTGGCGAACTGGCCGAAGTGCTCGGGCCGAAACTGCTCGACACCGACAAGTTGTTCCGCAG
CCTGCGCATCCGCGAGCGGGCCGCCAGTTACGTGGCCGGCCTCGACAAGCAGTCGCCCGCGTGGAAAGGCCTGCAAGCCT
ATCTGGACGGCATTAACCAGTATCAGGACTCGCACGCCGCCCCCGTCGAGTTCGACGTGCTGGGCATCCCCAAGCGGCCG
TTCACCGCCGAGGACAGCATCAGCGTCGCCGGCTACATGGCCTACAGCTTTGCCGCCGCGTTTCGCACCGAACCGCTCCT
GACCTACGTACGCGATCAACTGGGCGCCGATTACCTCAACGTGTTCGACCTCGACTGGCAACCCAAGGGCGTGCTCGCCA
AGGGCCACGCCGGCACCGCACCGGCCCTCGCTGCCGAAGACTGGAAAGACCTGAACACCCTCGCCCGCGTCAGCGAGCAG
GCATTGATCGACAACGGTCTGCCGCAGTTCGAAGGCAGCAACGCCTGGGTGATCGCCGGCAGCCACAGCAAGAGCGCCAA
GCCTTTGCTGGCCGGCGATCCGCACATTCGTTTTTCGGTGCCGTCGGTGTGGTACGAGGCGCAGTTGTCGGCGCCGGGTT
TTGAACTCTACGGCCATCATCAGGCGCTGGTGCCGTTCGCGTTTCTCGGCCACAACCTGGATTTCGGCTGGAGCCTGACC
ATGTTCCAGAACGACGACCTCGATCTGATCGCCGAGAAGGTCAATCCGGACAACCCGGATCAGGTCTGGTATCGCGGCCA
GTGGACCGACATGGTCAAGACCGAGCAGCAGATCGCGGTGAAAGGCCAGGCCCCGATGTCCATCACGTTGCGCCAGTCGC
CCCACGGCCCAATCGTCAACGACGCCCTCGGTACAGCCGCAGGGAAAACCCCGATTGCGATGTGGTGGGCGTTCCTCGAA
ACACCGAACCCGATCCTCGAAGGTTTTTACCAGCTCAACCGCGCCGACACCCTGGCCAAGGCCCGCGCCGCAGCGGCCAA
GGTGCAGGCACCGGGGCTGAACATCGTCTACGCCAACGCCAAGGGCGATATCGCGTGGTGGGCCTCGGCGCTGCTGCCCA
AACGGCCGGCCGGGGTGAAGCCTGGGTTCATTCTCGACGGCAGCGGCAATCAGGCGGACAAGGACGGCTACTTCCCGTTC
AGCGCCAACCCGCAGGAAGAGAACCCGGCGCGGGGCTATATCGTCTCGGCCAACTTCCAGCCCGTGTCGCCGACCGGCAT
GGAGATTCCCGGTTATTACAACCTCGCCGACCGTGGCCAGCAGCTCAACCGCCAGCTCGCCGACAAGAACGTGAAATGGG
ACAACGAGGCCAACCAGAAGCTGCAACTGGGCACCACCACCGGTTACGGTCCGCGTCTGCTGGCGCCGTTGCTGCCGGTG
CTGCGTGAAGTGGCGGGCAATCCCGCCGAGCAGAAGCTGATCGAGCAACTGGCCCAGTGGCAAGGCGACTATCCGCTGGA
TTCGGTCAGTGCGACGGTGTTCAACCAGTTCCTGTTCAACCTCGCCGACGCGGCAATGCGCGATGAGCTGGGCAATGATT
TCTTCGAAACCCTGCTGTCGACCCGGGTGATCGATGCGGCACTGCCCCGGCTCGCGGCGAATGCCGATTCACCGTGGTGG
GACAACCGCAGCACGCCGAACAAGGAGACCCGCGTCGACACCGTGCGCGCCGCGTGGCAGGCGAGCATGGCCCACCTGAA
GTCGACCCTCGGCGACGACGCTTCCGGCTGGCAATGGGGCAAGGCGCATACGCTGACCCATGGTCATCCGCTGGGTCAGC
AGAAGCCGCTGGATCGCATTTTCAACGTCGGCCCCTTCGCCGCACCGGGCTCCCATGAAGTGCCGAACAACCTCTCGGCG
AAGATCGGCCCGGCGCCGTGGCCGGTGACCTACGGCCCGTCGACCCGGCGCTTGGTGGACTTCGCTGATCCGGCTCACAG
CCTGACCATCAACCCGGTGGGCCAGAGCGGCGTGCCGTTCGACAGCCACTATGACGATCAGGCAGAGGCGTATGTGGACG
GGATGTATGTGCAGGCGCATTTCAGTGAGGAAGAGGTGACGGCGAATACGCGCAGTACCTTGAAGCTGTTGCCGGCGCGA
GCGGCGCAATAA

Upstream 100 bases:

>100_bases
TTCAAGAAATACTGTGTTATGAAATCCCGGTTGCGATCTTCAACTAGATCAGCAGCATCAATGCCTTCATATAAATAGAA
CGACAGGGAGCAGATTTTTC

Downstream 100 bases:

>100_bases
GCGCCGCTCAAACCATCGCCGCAAAATTCAGCCGGAACTGCTGCGGCGTCACCCCCAGCCGCCGGTTGAACACACTGCGC
ATATGTTGCGCATCGCGAAA

Product: penicillin amidase

Products: NA

Alternate protein names: AHL acylase quiP; Acyl-HSL acylase quiP; Quorum signal utilization and inactivation protein; Acyl-HSL acylase quiP subunit alpha; Acyl-HSL acylase quiP subunit beta [H]

Number of amino acids: Translated: 803; Mature: 803

Protein sequence:

>803_residues
MKKGLTVLALLIVIPAIGVGGYLYSKQPTRQGQVELRNLQGSVTVRYDERGVPHIRAENEIDLYRALGYVHAQDRLFQME
AMRRLARGELAEVLGPKLLDTDKLFRSLRIRERAASYVAGLDKQSPAWKGLQAYLDGINQYQDSHAAPVEFDVLGIPKRP
FTAEDSISVAGYMAYSFAAAFRTEPLLTYVRDQLGADYLNVFDLDWQPKGVLAKGHAGTAPALAAEDWKDLNTLARVSEQ
ALIDNGLPQFEGSNAWVIAGSHSKSAKPLLAGDPHIRFSVPSVWYEAQLSAPGFELYGHHQALVPFAFLGHNLDFGWSLT
MFQNDDLDLIAEKVNPDNPDQVWYRGQWTDMVKTEQQIAVKGQAPMSITLRQSPHGPIVNDALGTAAGKTPIAMWWAFLE
TPNPILEGFYQLNRADTLAKARAAAAKVQAPGLNIVYANAKGDIAWWASALLPKRPAGVKPGFILDGSGNQADKDGYFPF
SANPQEENPARGYIVSANFQPVSPTGMEIPGYYNLADRGQQLNRQLADKNVKWDNEANQKLQLGTTTGYGPRLLAPLLPV
LREVAGNPAEQKLIEQLAQWQGDYPLDSVSATVFNQFLFNLADAAMRDELGNDFFETLLSTRVIDAALPRLAANADSPWW
DNRSTPNKETRVDTVRAAWQASMAHLKSTLGDDASGWQWGKAHTLTHGHPLGQQKPLDRIFNVGPFAAPGSHEVPNNLSA
KIGPAPWPVTYGPSTRRLVDFADPAHSLTINPVGQSGVPFDSHYDDQAEAYVDGMYVQAHFSEEEVTANTRSTLKLLPAR
AAQ

Sequences:

>Translated_803_residues
MKKGLTVLALLIVIPAIGVGGYLYSKQPTRQGQVELRNLQGSVTVRYDERGVPHIRAENEIDLYRALGYVHAQDRLFQME
AMRRLARGELAEVLGPKLLDTDKLFRSLRIRERAASYVAGLDKQSPAWKGLQAYLDGINQYQDSHAAPVEFDVLGIPKRP
FTAEDSISVAGYMAYSFAAAFRTEPLLTYVRDQLGADYLNVFDLDWQPKGVLAKGHAGTAPALAAEDWKDLNTLARVSEQ
ALIDNGLPQFEGSNAWVIAGSHSKSAKPLLAGDPHIRFSVPSVWYEAQLSAPGFELYGHHQALVPFAFLGHNLDFGWSLT
MFQNDDLDLIAEKVNPDNPDQVWYRGQWTDMVKTEQQIAVKGQAPMSITLRQSPHGPIVNDALGTAAGKTPIAMWWAFLE
TPNPILEGFYQLNRADTLAKARAAAAKVQAPGLNIVYANAKGDIAWWASALLPKRPAGVKPGFILDGSGNQADKDGYFPF
SANPQEENPARGYIVSANFQPVSPTGMEIPGYYNLADRGQQLNRQLADKNVKWDNEANQKLQLGTTTGYGPRLLAPLLPV
LREVAGNPAEQKLIEQLAQWQGDYPLDSVSATVFNQFLFNLADAAMRDELGNDFFETLLSTRVIDAALPRLAANADSPWW
DNRSTPNKETRVDTVRAAWQASMAHLKSTLGDDASGWQWGKAHTLTHGHPLGQQKPLDRIFNVGPFAAPGSHEVPNNLSA
KIGPAPWPVTYGPSTRRLVDFADPAHSLTINPVGQSGVPFDSHYDDQAEAYVDGMYVQAHFSEEEVTANTRSTLKLLPAR
AAQ
>Mature_803_residues
MKKGLTVLALLIVIPAIGVGGYLYSKQPTRQGQVELRNLQGSVTVRYDERGVPHIRAENEIDLYRALGYVHAQDRLFQME
AMRRLARGELAEVLGPKLLDTDKLFRSLRIRERAASYVAGLDKQSPAWKGLQAYLDGINQYQDSHAAPVEFDVLGIPKRP
FTAEDSISVAGYMAYSFAAAFRTEPLLTYVRDQLGADYLNVFDLDWQPKGVLAKGHAGTAPALAAEDWKDLNTLARVSEQ
ALIDNGLPQFEGSNAWVIAGSHSKSAKPLLAGDPHIRFSVPSVWYEAQLSAPGFELYGHHQALVPFAFLGHNLDFGWSLT
MFQNDDLDLIAEKVNPDNPDQVWYRGQWTDMVKTEQQIAVKGQAPMSITLRQSPHGPIVNDALGTAAGKTPIAMWWAFLE
TPNPILEGFYQLNRADTLAKARAAAAKVQAPGLNIVYANAKGDIAWWASALLPKRPAGVKPGFILDGSGNQADKDGYFPF
SANPQEENPARGYIVSANFQPVSPTGMEIPGYYNLADRGQQLNRQLADKNVKWDNEANQKLQLGTTTGYGPRLLAPLLPV
LREVAGNPAEQKLIEQLAQWQGDYPLDSVSATVFNQFLFNLADAAMRDELGNDFFETLLSTRVIDAALPRLAANADSPWW
DNRSTPNKETRVDTVRAAWQASMAHLKSTLGDDASGWQWGKAHTLTHGHPLGQQKPLDRIFNVGPFAAPGSHEVPNNLSA
KIGPAPWPVTYGPSTRRLVDFADPAHSLTINPVGQSGVPFDSHYDDQAEAYVDGMYVQAHFSEEEVTANTRSTLKLLPAR
AAQ

Specific function: Catalyzes the deacylation of acyl-homoserine lactone (AHL or acyl-HSL), releasing homoserine lactone (HSL) and the corresponding fatty acid. Possesses a specificity for the degradation of long-chain acyl-HSLs (side chains of seven or more carbons in lengt

COG id: COG2366

COG function: function code R; Protein related to penicillin acylase

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S45 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014395
- InterPro:   IPR002692 [H]

Pfam domain/function: PF01804 Penicil_amidase [H]

EC number: =3.5.1.97 [H]

Molecular weight: Translated: 88245; Mature: 88245

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS00599 AA_TRANSFER_CLASS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKGLTVLALLIVIPAIGVGGYLYSKQPTRQGQVELRNLQGSVTVRYDERGVPHIRAENE
CCCCHHHHHHHHHHHHHCCCCEEECCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCCCC
IDLYRALGYVHAQDRLFQMEAMRRLARGELAEVLGPKLLDTDKLFRSLRIRERAASYVAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHC
LDKQSPAWKGLQAYLDGINQYQDSHAAPVEFDVLGIPKRPFTAEDSISVAGYMAYSFAAA
CCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHH
FRTEPLLTYVRDQLGADYLNVFDLDWQPKGVLAKGHAGTAPALAAEDWKDLNTLARVSEQ
HHCCHHHHHHHHHHCCCEEEEEECCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHH
ALIDNGLPQFEGSNAWVIAGSHSKSAKPLLAGDPHIRFSVPSVWYEAQLSAPGFELYGHH
HHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCEEEECCCEEEEEECCCCCCEECCCC
QALVPFAFLGHNLDFGWSLTMFQNDDLDLIAEKVNPDNPDQVWYRGQWTDMVKTEQQIAV
HHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHCCCCCCCCEEECCCCHHHHHCCHHEEE
KGQAPMSITLRQSPHGPIVNDALGTAAGKTPIAMWWAFLETPNPILEGFYQLNRADTLAK
ECCCCEEEEEECCCCCCCCHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
ARAAAAKVQAPGLNIVYANAKGDIAWWASALLPKRPAGVKPGFILDGSGNQADKDGYFPF
HHHHHHHCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCC
SANPQEENPARGYIVSANFQPVSPTGMEIPGYYNLADRGQQLNRQLADKNVKWDNEANQK
CCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCE
LQLGTTTGYGPRLLAPLLPVLREVAGNPAEQKLIEQLAQWQGDYPLDSVSATVFNQFLFN
EEECCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
LADAAMRDELGNDFFETLLSTRVIDAALPRLAANADSPWWDNRSTPNKETRVDTVRAAWQ
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHH
ASMAHLKSTLGDDASGWQWGKAHTLTHGHPLGQQKPLDRIFNVGPFAAPGSHEVPNNLSA
HHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCC
KIGPAPWPVTYGPSTRRLVDFADPAHSLTINPVGQSGVPFDSHYDDQAEAYVDGMYVQAH
CCCCCCCCCCCCCCCCEEEEECCCCCEEEECCCCCCCCCCCCCCCCHHHHHHCCEEEEEE
FSEEEVTANTRSTLKLLPARAAQ
CCCHHHCCCCHHHHHHCCCCCCC
>Mature Secondary Structure
MKKGLTVLALLIVIPAIGVGGYLYSKQPTRQGQVELRNLQGSVTVRYDERGVPHIRAENE
CCCCHHHHHHHHHHHHHCCCCEEECCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCCCC
IDLYRALGYVHAQDRLFQMEAMRRLARGELAEVLGPKLLDTDKLFRSLRIRERAASYVAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHC
LDKQSPAWKGLQAYLDGINQYQDSHAAPVEFDVLGIPKRPFTAEDSISVAGYMAYSFAAA
CCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHH
FRTEPLLTYVRDQLGADYLNVFDLDWQPKGVLAKGHAGTAPALAAEDWKDLNTLARVSEQ
HHCCHHHHHHHHHHCCCEEEEEECCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHH
ALIDNGLPQFEGSNAWVIAGSHSKSAKPLLAGDPHIRFSVPSVWYEAQLSAPGFELYGHH
HHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCEEEECCCEEEEEECCCCCCEECCCC
QALVPFAFLGHNLDFGWSLTMFQNDDLDLIAEKVNPDNPDQVWYRGQWTDMVKTEQQIAV
HHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHCCCCCCCCEEECCCCHHHHHCCHHEEE
KGQAPMSITLRQSPHGPIVNDALGTAAGKTPIAMWWAFLETPNPILEGFYQLNRADTLAK
ECCCCEEEEEECCCCCCCCHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
ARAAAAKVQAPGLNIVYANAKGDIAWWASALLPKRPAGVKPGFILDGSGNQADKDGYFPF
HHHHHHHCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCC
SANPQEENPARGYIVSANFQPVSPTGMEIPGYYNLADRGQQLNRQLADKNVKWDNEANQK
CCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCE
LQLGTTTGYGPRLLAPLLPVLREVAGNPAEQKLIEQLAQWQGDYPLDSVSATVFNQFLFN
EEECCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
LADAAMRDELGNDFFETLLSTRVIDAALPRLAANADSPWWDNRSTPNKETRVDTVRAAWQ
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHH
ASMAHLKSTLGDDASGWQWGKAHTLTHGHPLGQQKPLDRIFNVGPFAAPGSHEVPNNLSA
HHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCC
KIGPAPWPVTYGPSTRRLVDFADPAHSLTINPVGQSGVPFDSHYDDQAEAYVDGMYVQAH
CCCCCCCCCCCCCCCCEEEEECCCCCEEEECCCCCCCCCCCCCCCCHHHHHHCCEEEEEE
FSEEEVTANTRSTLKLLPARAAQ
CCCHHHCCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]