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The map label for this gene is dhaT [H]

Identifier: 77461342

GI number: 77461342

Start: 5753505

End: 5754653

Strand: Reverse

Name: dhaT [H]

Synonym: Pfl01_5121

Alternate gene names: 77461342

Gene position: 5754653-5753505 (Counterclockwise)

Preceding gene: 77461343

Following gene: 77461341

Centisome position: 89.38

GC content: 63.62

Gene sequence:

>1149_bases
ATGAGTCTTTCCTCGTTCAAGATCGCTCACAAACTGATCACCGGCGCCGGGGCCATCGAGCAACTGGCGGCCGAACTCAC
GCGGCTGGACATCGACAACCCGCTGATCGTCACCGATGCCGCGCTGGTCAAGTCCGGCACGGTGGAGCTGGCGCTGGCGC
AGATCGGCGAGCGCGAGTACGAAATCTTCGACCGGGTATTGCCGGATCCGGAAATCGCCATCGTCGAGGATTGCATGCGC
GTCTACCGCGAAGGCGGGCATGACGGTCTGATTGGCCTCGGTGGCGGCAGTGCCATCGACATCGCCAAGAGCGTCGCGGC
GTACGCCGGCTATCACGGTGCGCTGGAAGATCTGTTCGGCGTCGATCAGGTGCCGCGCAAAGGCCCACCGTTGATTGCGA
TCCCGACCACTGCCGGCACCGGTTCTGAAGTGACCAACGTCGCCATCCTTTCGGACAAGGTCGCCCAACTGAAGAAAGGC
ATCGTCAGCGATTACCTGTTGCCGGACGTGGCGCTGGTCAGTCCGCAGATGACCCTGACCTGCCCGCGCAGTGTCACCGC
CGCCAGTGGCGTCGATGCGCTGGTGCATGCCATCGAATCCTATCTGTCACTGAATGCCTCGCCGATCACCGATTCGCTGG
CCATCGGCGCAATCAAGTTGATCGCCCGGTCCTTGCCCAAGGCCTACGCGAACCCCTCCAACCTGCAGGCCAGGGAAGAC
ATGGCCACTGCCAGCCTGATGGCCGGCATGGCGTTCGGCAATGCCGGGGTCGGCGCGGTGCATGCGCTGGCGTATCCGCT
GGGCGGGCGATTCAACATTGCTCACGGCGTCAGCAATGCGTTGCTGCTGCCGTATGTCATGACCTGGAACAAGATGGCCT
GCGTCGAACGGATGCAGGATATCGCCGAAGCCATGGGGGTGAAGACCGCTCATCTGAGTCTCAATGAAGCGGCCGACAGC
GCCGTCGCCGCGATGACCGAGCTCTGTGCGGCGGTGGAAATCCCGCTGGGTCTGCGCAGTTTCGGCGTGCCCGAAGAAGC
GATCCCGGCCATGGCCGTGGAGGCAGCGGGAATCGAGCGCCTGATGCGCAACAACCCGCGCAAGCTCAGCGCCGCCGACA
TCGAGAAGATCTACCGGGCGGCGTACTGA

Upstream 100 bases:

>100_bases
CAATCCGGGTTGTCTGCCATTCATGCGCTGAATGACAGACAACCCGATTTCCCCAGCTACGCTTGTGCTCAGCTCCCACA
TCTATAAGAGGCTGCGCACG

Downstream 100 bases:

>100_bases
GAACCCGCCGGTCATCGGTCATGGCACAACCCAATCATCGCGGTCACGGTGCGCGCGCGGAAACTTGAGGTATACAATGC
GCGCCATCGTGATTTAGCTC

Product: Iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: 1,3-propanediol oxidoreductase; 3-hydroxypropionaldehyde reductase [H]

Number of amino acids: Translated: 382; Mature: 381

Protein sequence:

>382_residues
MSLSSFKIAHKLITGAGAIEQLAAELTRLDIDNPLIVTDAALVKSGTVELALAQIGEREYEIFDRVLPDPEIAIVEDCMR
VYREGGHDGLIGLGGGSAIDIAKSVAAYAGYHGALEDLFGVDQVPRKGPPLIAIPTTAGTGSEVTNVAILSDKVAQLKKG
IVSDYLLPDVALVSPQMTLTCPRSVTAASGVDALVHAIESYLSLNASPITDSLAIGAIKLIARSLPKAYANPSNLQARED
MATASLMAGMAFGNAGVGAVHALAYPLGGRFNIAHGVSNALLLPYVMTWNKMACVERMQDIAEAMGVKTAHLSLNEAADS
AVAAMTELCAAVEIPLGLRSFGVPEEAIPAMAVEAAGIERLMRNNPRKLSAADIEKIYRAAY

Sequences:

>Translated_382_residues
MSLSSFKIAHKLITGAGAIEQLAAELTRLDIDNPLIVTDAALVKSGTVELALAQIGEREYEIFDRVLPDPEIAIVEDCMR
VYREGGHDGLIGLGGGSAIDIAKSVAAYAGYHGALEDLFGVDQVPRKGPPLIAIPTTAGTGSEVTNVAILSDKVAQLKKG
IVSDYLLPDVALVSPQMTLTCPRSVTAASGVDALVHAIESYLSLNASPITDSLAIGAIKLIARSLPKAYANPSNLQARED
MATASLMAGMAFGNAGVGAVHALAYPLGGRFNIAHGVSNALLLPYVMTWNKMACVERMQDIAEAMGVKTAHLSLNEAADS
AVAAMTELCAAVEIPLGLRSFGVPEEAIPAMAVEAAGIERLMRNNPRKLSAADIEKIYRAAY
>Mature_381_residues
SLSSFKIAHKLITGAGAIEQLAAELTRLDIDNPLIVTDAALVKSGTVELALAQIGEREYEIFDRVLPDPEIAIVEDCMRV
YREGGHDGLIGLGGGSAIDIAKSVAAYAGYHGALEDLFGVDQVPRKGPPLIAIPTTAGTGSEVTNVAILSDKVAQLKKGI
VSDYLLPDVALVSPQMTLTCPRSVTAASGVDALVHAIESYLSLNASPITDSLAIGAIKLIARSLPKAYANPSNLQAREDM
ATASLMAGMAFGNAGVGAVHALAYPLGGRFNIAHGVSNALLLPYVMTWNKMACVERMQDIAEAMGVKTAHLSLNEAADSA
VAAMTELCAAVEIPLGLRSFGVPEEAIPAMAVEAAGIERLMRNNPRKLSAADIEKIYRAAY

Specific function: Most active with substrates containing two primary alcohol groups separated by one or two carbon atoms. In the physiological direction, 3-hydroxypropionaldehyde is the preferred substrate [H]

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=409, Percent_Identity=29.8288508557457, Blast_Score=152, Evalue=4e-37,
Organism=Escherichia coli, GI48994951, Length=383, Percent_Identity=38.9033942558747, Blast_Score=249, Evalue=2e-67,
Organism=Escherichia coli, GI1789163, Length=376, Percent_Identity=38.563829787234, Blast_Score=230, Evalue=1e-61,
Organism=Escherichia coli, GI87082107, Length=381, Percent_Identity=37.7952755905512, Blast_Score=218, Evalue=5e-58,
Organism=Escherichia coli, GI1787493, Length=347, Percent_Identity=32.8530259365994, Blast_Score=152, Evalue=5e-38,
Organism=Escherichia coli, GI1789386, Length=392, Percent_Identity=26.530612244898, Blast_Score=103, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17537053, Length=396, Percent_Identity=29.7979797979798, Blast_Score=145, Evalue=5e-35,
Organism=Saccharomyces cerevisiae, GI6321181, Length=389, Percent_Identity=37.2750642673522, Blast_Score=219, Evalue=4e-58,
Organism=Drosophila melanogaster, GI24657991, Length=405, Percent_Identity=29.3827160493827, Blast_Score=146, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.202 [H]

Molecular weight: Translated: 39989; Mature: 39857

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSSFKIAHKLITGAGAIEQLAAELTRLDIDNPLIVTDAALVKSGTVELALAQIGEREY
CCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEECHHHHHCCCHHHHHHHHCCHHH
EIFDRVLPDPEIAIVEDCMRVYREGGHDGLIGLGGGSAIDIAKSVAAYAGYHGALEDLFG
HHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHCCHHHHHHHHC
VDQVPRKGPPLIAIPTTAGTGSEVTNVAILSDKVAQLKKGIVSDYLLPDVALVSPQMTLT
CCCCCCCCCCEEEECCCCCCCCHHHEEHHHHHHHHHHHHHHHHHHHCCCHHHCCCCEEEE
CPRSVTAASGVDALVHAIESYLSLNASPITDSLAIGAIKLIARSLPKAYANPSNLQARED
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
MATASLMAGMAFGNAGVGAVHALAYPLGGRFNIAHGVSNALLLPYVMTWNKMACVERMQD
HHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEHHHCCCCHHHHHHHHHHHHHHHHHHHHH
IAEAMGVKTAHLSLNEAADSAVAAMTELCAAVEIPLGLRSFGVPEEAIPAMAVEAAGIER
HHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHH
LMRNNPRKLSAADIEKIYRAAY
HHHCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
SLSSFKIAHKLITGAGAIEQLAAELTRLDIDNPLIVTDAALVKSGTVELALAQIGEREY
CCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEECHHHHHCCCHHHHHHHHCCHHH
EIFDRVLPDPEIAIVEDCMRVYREGGHDGLIGLGGGSAIDIAKSVAAYAGYHGALEDLFG
HHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHCCHHHHHHHHC
VDQVPRKGPPLIAIPTTAGTGSEVTNVAILSDKVAQLKKGIVSDYLLPDVALVSPQMTLT
CCCCCCCCCCEEEECCCCCCCCHHHEEHHHHHHHHHHHHHHHHHHHCCCHHHCCCCEEEE
CPRSVTAASGVDALVHAIESYLSLNASPITDSLAIGAIKLIARSLPKAYANPSNLQARED
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
MATASLMAGMAFGNAGVGAVHALAYPLGGRFNIAHGVSNALLLPYVMTWNKMACVERMQD
HHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEHHHCCCCHHHHHHHHHHHHHHHHHHHHH
IAEAMGVKTAHLSLNEAADSAVAAMTELCAAVEIPLGLRSFGVPEEAIPAMAVEAAGIER
HHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHH
LMRNNPRKLSAADIEKIYRAAY
HHHCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7721705 [H]